Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0004 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Toxoplasma gondii | carbonyl reductase 1, putative | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Leishmania major | quinonoid dihydropteridine reductase | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain membrane-associated dehydrogenase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | dehydrogenases, short chain protein 2 | 0.0004 | 0.5 | 0.5 |
Mycobacterium leprae | Probable oxidoreductase | 0.0004 | 0.5 | 0.5 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | dehydrogenase | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | dehydrogenase | 0.0004 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | epidermal retinal dehydrogenase 2 | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 1 homolog | 0.0004 | 0.5 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Brugia malayi | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | retinol dehydrogenase 11 | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | retinol dehydrogenase 13 | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0004 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, putative | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | estradiol 17 beta dehydrogenase 12 | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Leishmania major | short chain dehydrogenase/reductase, putative | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | oxidoreductase short chain dehydrogenase/reductase family | 0.0004 | 0.5 | 0.5 |
Leishmania major | short chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Trichomonas vaginalis | hydroxyacyl dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Entamoeba histolytica | short chain dehydrogenase family protein | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible short-chain dehydrogenase EphD | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Leishmania major | pteridine reductase 1 | 0.0004 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | Dehydrogenase:reductase SDR family | 0.0004 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Schistosoma mansoni | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | carveol-like dehydrogenase | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | dehydrogenase/decarboxylase protein | 0.0004 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Trypanosoma brucei | 3-ketoacyl-CoA reductase, putative | 0.0004 | 0.5 | 0.5 |
Entamoeba histolytica | short chain dehydrogenase family protein | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | Dehydrogenases, short chain protein 30 | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | 3 ketodihydrosphingosine reductase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Leishmania major | dehydrogenase-like protein | 0.0004 | 0.5 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Brugia malayi | D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Toxoplasma gondii | sterol carrier protein-2 HAD-2SCP-2 | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Trypanosoma brucei | 3-keto-dihydrosphingosine reductase | 0.0004 | 0.5 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | carbonyl reductase | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Mycobacterium ulcerans | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase 2 | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Mycobacterium leprae | PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | retinal dehydrogenase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Leishmania major | short chain dehydrogenase/reductase, putative | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Leishmania major | oxidoreductase-like protein | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0004 | 0.5 | 0.5 |
Giardia lamblia | Oxidoreductase, short chain dehydrogenase/reductase family | 0.0004 | 0.5 | 0.5 |
Mycobacterium leprae | ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | 0.0004 | 0.5 | 0.5 |
Brugia malayi | Hypothetical oxidoreductase F56D1.5 | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0004 | 0.5 | 0.5 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0004 | 0.5 | 0.5 |
Plasmodium falciparum | steroid dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Brugia malayi | Retinol dehydrogenase 12 | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type oxidoreductase | 0.0004 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenases/reductase, putative | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | retinol dehydrogenase 11 | 0.0004 | 0.5 | 0.5 |
Trichomonas vaginalis | steroid dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | carbonyl reductase | 0.0004 | 0.5 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | carbonyl reductase | 0.0004 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Leishmania major | short chain dehydrogenase-like protein | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | 3 ketodihydrosphingosine reductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium leprae | Possible short-chain dehydrogenase EphD | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0004 | 0.5 | 0.5 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0004 | 0.5 | 0.5 |
Toxoplasma gondii | 3-ketoacyl-CoA reductase, putative | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, putative | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible ketoacyl reductase | 0.0004 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Decaprenylphosphoryl-D-2-keto erythro pentose reductase | 0.0004 | 0.5 | 0.5 |
Entamoeba histolytica | oxidoreductase, short chain dehydrogenase/reductase family | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | Sepiapterin reductase homolog | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | 3-keto-dihydrosphingosine reductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Plasmodium vivax | steroid dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible iron-regulated short-chain dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Leishmania major | 3-keto-dihydrosphingosine reductase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | epidermal retinal dehydrogenase 2 | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | quinonoid dihydropteridine reductase, putative | 0.0004 | 0.5 | 0.5 |
Brugia malayi | dehydrogenases, short chain protein 9 | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Echinococcus multilocularis | Dehydrogenase:reductase SDR family | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0004 | 0.5 | 0.5 |
Trypanosoma brucei | beta-D-hydroxybutyrate dehydrogenase | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0004 | 0.5 | 0.5 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase 3, putative | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Echinococcus multilocularis | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Trichomonas vaginalis | estradiol 17 beta-dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short chain alcohol dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0004 | 0.5 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Brugia malayi | Dehydrogenases, short chain protein 2 | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible fatty acyl-CoA reductase | 0.0004 | 0.5 | 0.5 |
Plasmodium falciparum | oxidoreductase, short-chain dehydrogenase family, putative | 0.0004 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Mycobacterium ulcerans | dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable shortchain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Giardia lamblia | Short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Leishmania major | short chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | WW domain containing oxidoreductase | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0004 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short-chain dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0004 | 0.5 | 0.5 |
Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | short chain dehydrogenase/reductase family oxidoreductase | 0.0004 | 0.5 | 0.5 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Entamoeba histolytica | 3-ketodihydrosphingosine reductase protein, putative | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0004 | 0.5 | 0.5 | |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Giardia lamblia | Reductase, putative | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type oxidoreductase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0004 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0004 | 0.5 | 0.5 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0004 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0004 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0004 | 0.5 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0004 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 0 % | Inhibition of Mycobacterium tuberculosis recombinant PKnG expressed in Escherichia coli BL21 (DE3) cells using myelin basic protein substrate at 3.125 uM by luciferase activity based ADP-Glo-luminescent kinase assay | ChEMBL. | 22854194 |
Inhibition (binding) | = 7 % | Inhibition of Mycobacterium tuberculosis recombinant PKnG expressed in Escherichia coli BL21 (DE3) cells using myelin basic protein substrate at 25 uM by luciferase activity based ADP-Glo-luminescent kinase assay | ChEMBL. | 22854194 |
Inhibition (binding) | = 9 % | Inhibition of Mycobacterium tuberculosis recombinant PKnG expressed in Escherichia coli BL21 (DE3) cells using myelin basic protein substrate at 6.25 uM by luciferase activity based ADP-Glo-luminescent kinase assay | ChEMBL. | 22854194 |
Inhibition (binding) | = 11 % | Inhibition of Mycobacterium tuberculosis recombinant PKnG expressed in Escherichia coli BL21 (DE3) cells using myelin basic protein substrate at 12.5 uM by luciferase activity based ADP-Glo-luminescent kinase assay | ChEMBL. | 22854194 |
Inhibition (binding) | = 25 % | Inhibition of Mycobacterium tuberculosis recombinant PKnG expressed in Escherichia coli BL21 (DE3) cells using myelin basic protein substrate at 50 uM by luciferase activity based ADP-Glo-luminescent kinase assay | ChEMBL. | 22854194 |
Inhibition (binding) | = 35 % | Inhibition of Mycobacterium tuberculosis recombinant PKnG expressed in Escherichia coli BL21 (DE3) cells using myelin basic protein substrate at 100 uM by luciferase activity based ADP-Glo-luminescent kinase assay | ChEMBL. | 22854194 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.