TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 342.871 | Formula: C14H27ClN8
H donors: 4 H acceptors: 3 LogP: -0.29 Rotable bonds: 11
Rule of 5 violations (Lipinski): 1
SMILES: NCCCNCCCNCCCn1cnc2c1ncnc2N.Cl
InChi: 1S/C14H26N8.ClH/c15-4-1-5-17-6-2-7-18-8-3-9-22-11-21-12-13(16)19-10-20-14(12)22;/h10-11,17-18H,1-9,15H2,(H2,16,19,20);1H
InChiKey: PBFDDJZKKGAUHG-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Onchocerca volvulus	Sepiapterin reductase homolog	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable dehydrogenase	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Trypanosoma brucei	beta-ketoacyl-ACP reductase 3, putative	0.0004	0.5	0.5
Toxoplasma gondii	2,4-dienoyl CoA reductase 2, peroxisomal family protein	0.0004	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Leishmania major	hypothetical protein, conserved	0.0004	0.5	0.5
Brugia malayi	hypothetical protein	0.0004	0.5	0.5
Plasmodium vivax	steroid dehydrogenase, putative	0.0004	0.5	0.5
Trypanosoma cruzi	NAD(P)-dependent oxidoreductase, putative	0.0004	0.5	0.5
Schistosoma mansoni	steroid dehydrogenase	0.0004	0.5	0.5
Trypanosoma cruzi	hypothetical protein, conserved	0.0004	0.5	0.5
Toxoplasma gondii	oxidoreductase, putative	0.0004	0.5	0.5
Loa Loa (eye worm)	oxidoreductase	0.0004	0.5	0.5
Plasmodium falciparum	steroid dehydrogenase, putative	0.0004	0.5	0.5
Giardia lamblia	Reductase, putative	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain dehydrogenase	0.0004	0.5	0.5
Entamoeba histolytica	estradiol 17-beta-dehydrogenase, putative	0.0004	0.5	0.5
Trypanosoma cruzi	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Trypanosoma brucei	3-ketoacyl-CoA reductase, putative	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable dehydrogenase/reductase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Leishmania major	quinonoid dihydropteridine reductase	0.0004	0.5	0.5
Mycobacterium ulcerans	dehydrogenase/decarboxylase protein	0.0004	0.5	0.5
Trypanosoma cruzi	3-keto-dihydrosphingosine reductase	0.0004	0.5	0.5
Trypanosoma cruzi	quinonoid dihydropteridine reductase, putative	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium leprae	PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE	0.0004	0.5	0.5
Leishmania major	3-keto-dihydrosphingosine reductase	0.0004	0.5	0.5
Toxoplasma gondii	3-ketoacyl-CoA reductase, putative	0.0004	0.5	0.5
Loa Loa (eye worm)	oxidoreductase	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable short-chain dehydrogenase/reductase	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Schistosoma mansoni	steroid dehydrogenase	0.0004	0.5	0.5
Leishmania major	hypothetical protein, conserved	0.0004	0.5	0.5
Mycobacterium ulcerans	3-ketoacyl-ACP reductase	0.0004	0.5	0.5
Toxoplasma gondii	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain dehydrogenase	0.0004	0.5	0.5
Trypanosoma cruzi	short chain dehydrogenase/reductase, putative	0.0004	0.5	0.5
Echinococcus granulosus	steroid dehydrogenase	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Trypanosoma cruzi	3-ketoacyl-CoA reductase, putative	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0004	0.5	0.5
Trypanosoma cruzi	beta-ketoacyl-ACP reductase 2, putative	0.0004	0.5	0.5
Plasmodium falciparum	oxidoreductase, short-chain dehydrogenase family, putative	0.0004	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0004	0.5	0.5
Echinococcus granulosus	hypothetical protein	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Mycobacterium leprae	Probable short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium tuberculosis	Possible fatty acyl-CoA reductase	0.0004	0.5	0.5
Echinococcus granulosus	carbonyl reductase 1	0.0004	0.5	0.5
Echinococcus multilocularis	carbonyl reductase 1	0.0004	0.5	0.5
Echinococcus multilocularis	Dehydrogenase:reductase SDR family	0.0004	0.5	0.5
Entamoeba histolytica	estradiol 17-beta-dehydrogenase, putative	0.0004	0.5	0.5
Brugia malayi	dehydrogenases, short chain protein 2	0.0004	0.5	0.5
Toxoplasma gondii	sterol carrier protein-2 HAD-2SCP-2	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable oxidoreductase	0.0004	0.5	0.5
Mycobacterium tuberculosis	Possible ketoacyl reductase	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Echinococcus multilocularis	estradiol 17 beta dehydrogenase 12	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0004	0.5	0.5
Toxoplasma gondii	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Plasmodium vivax	hypothetical protein, conserved	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Entamoeba histolytica	estradiol 17-beta-dehydrogenase, putative	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Echinococcus multilocularis	conserved hypothetical protein	0.0004	0.5	0.5
Loa Loa (eye worm)	oxidoreductase	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Giardia lamblia	Short-chain dehydrogenase, putative	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	ketoacyl reductase	0.0004	0.5	0.5
Trypanosoma brucei	3-keto-dihydrosphingosine reductase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Trypanosoma cruzi	oxidoreductase-like protein, putative	0.0004	0.5	0.5
Mycobacterium tuberculosis	Possible short-chain dehydrogenase EphD	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Echinococcus multilocularis	steroid dehydrogenase	0.0004	0.5	0.5
Trypanosoma brucei	beta-D-hydroxybutyrate dehydrogenase	0.0004	0.5	0.5
Loa Loa (eye worm)	oxidoreductase	0.0004	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0004	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Entamoeba histolytica	hypothetical protein, conserved	0.0004	0.5	0.5
Trichomonas vaginalis	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Entamoeba histolytica	oxidoreductase, short chain dehydrogenase/reductase family	0.0004	0.5	0.5
Trypanosoma brucei	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Schistosoma mansoni	steroid dehydrogenase	0.0004	0.5	0.5
Echinococcus granulosus	carbonyl reductase 1	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable dehydrogenase/reductase	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Leishmania major	short chain dehydrogenase-like protein	0.0004	0.5	0.5
Schistosoma mansoni	steroid dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable short-chain type oxidoreductase	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Echinococcus multilocularis	transient receptor potential cation channel	0.0004	0.5	0.5
Entamoeba histolytica	short chain dehydrogenase family protein	0.0004	0.5	0.5
Echinococcus granulosus	WW domain containing oxidoreductase	0.0004	0.5	0.5
Schistosoma mansoni	carbonyl reductase	0.0004	0.5	0.5
Echinococcus multilocularis	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0004	0.5	0.5
Trichomonas vaginalis	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable short chain alcohol dehydrogenase/reductase	0.0004	0.5	0.5
Brugia malayi	Retinol dehydrogenase 12	0.0004	0.5	0.5
Schistosoma mansoni	steroid dehydrogenase	0.0004	0.5	0.5
Echinococcus multilocularis	retinol dehydrogenase 11	0.0004	0.5	0.5
Trypanosoma brucei	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Schistosoma mansoni	3-keto-dihydrosphingosine reductase	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable oxidoreductase	0.0004	0.5	0.5
Trichomonas vaginalis	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Trichomonas vaginalis	estradiol 17 beta-dehydrogenase, putative	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Entamoeba histolytica	hypothetical protein, conserved	0.0004	0.5	0.5
Trypanosoma cruzi	hypothetical protein, conserved	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Schistosoma mansoni	steroid dehydrogenase	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0004	0.5	0.5
Echinococcus granulosus	epidermal retinal dehydrogenase 2	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Echinococcus multilocularis	retinol dehydrogenase 13	0.0004	0.5	0.5
Onchocerca volvulus	Dehydrogenase\/reductase SDR family member 13 homolog	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Trypanosoma brucei	beta-ketoacyl-ACP reductase 2	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Mycobacterium tuberculosis	Possible oxidoreductase	0.0004	0.5	0.5
Trypanosoma cruzi	hypothetical protein, conserved	0.0004	0.5	0.5
Mycobacterium ulcerans	3-alpha-hydroxysteroid dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	ketoacyl reductase	0.0004	0.5	0.5
Brugia malayi	hypothetical protein	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium leprae	ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE	0.0004	0.5	0.5
Trichomonas vaginalis	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Leishmania major	pteridine reductase 1	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable shortchain dehydrogenase	0.0004	0.5	0.5
Trypanosoma cruzi	hypothetical protein, conserved	0.0004	0.5	0.5
Trypanosoma cruzi	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable oxidoreductase	0.0004	0.5	0.5
Brugia malayi	D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Mycobacterium tuberculosis	Possible iron-regulated short-chain dehydrogenase/reductase	0.0004	0.5	0.5
Leishmania major	dehydrogenase-like protein	0.0004	0.5	0.5
Trypanosoma cruzi	3-keto-dihydrosphingosine reductase	0.0004	0.5	0.5
Trypanosoma cruzi	hypothetical protein, conserved	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Schistosoma mansoni	carbonyl reductase	0.0004	0.5	0.5
Leishmania major	quinonoid dihydropteridine reductase	0.0004	0.5	0.5
Entamoeba histolytica	short chain dehydrogenase family protein	0.0004	0.5	0.5
Mycobacterium tuberculosis	Possible oxidoreductase	0.0004	0.5	0.5
Trypanosoma brucei	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Mycobacterium ulcerans	ketoacyl reductase	0.0004	0.5	0.5
Schistosoma mansoni	3-hydroxyacyl-CoA dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain membrane-associated dehydrogenase	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Schistosoma mansoni	steroid dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Echinococcus multilocularis	carbonyl reductase 1	0.0004	0.5	0.5
Leishmania major	3-oxoacyl-(acyl-carrier protein) reductase, putative	0.0004	0.5	0.5
Echinococcus multilocularis	carbonyl reductase 1	0.0004	0.5	0.5
Leishmania major	short chain dehydrogenase/reductase, putative	0.0004	0.5	0.5
Trypanosoma cruzi	short chain dehydrogenase, putative	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Mycobacterium ulcerans	dehydrogenase/reductase	0.0004	0.5	0.5
Schistosoma mansoni	steroid dehydrogenase	0.0004	0.5	0.5
Schistosoma mansoni	short-chain dehydrogenase/reductase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Schistosoma mansoni	retinal dehydrogenase	0.0004	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable oxidoreductase	0.0004	0.5	0.5
Loa Loa (eye worm)	oxidoreductase	0.0004	0.5	0.5
Echinococcus multilocularis	oxidoreductase	0.0004	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0004	0.5	0.5
Loa Loa (eye worm)	oxidoreductase	0.0004	0.5	0.5
Leishmania major	hypothetical protein, conserved	0.0004	0.5	0.5
Onchocerca volvulus	Dehydrogenase\/reductase SDR family member 1 homolog	0.0004	0.5	0.5
Echinococcus granulosus	3 ketodihydrosphingosine reductase	0.0004	0.5	0.5
Brugia malayi	oxidoreductase	0.0004	0.5	0.5
Echinococcus multilocularis	carbonyl reductase 1	0.0004	0.5	0.5
Leishmania major	short chain dehydrogenase/reductase, putative	0.0004	0.5	0.5
Trypanosoma cruzi	oxidoreductase-like protein, putative	0.0004	0.5	0.5
Loa Loa (eye worm)	short chain dehydrogenase/reductase family oxidoreductase	0.0004	0.5	0.5
Loa Loa (eye worm)	oxidoreductase	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Trichomonas vaginalis	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Leishmania major	quinonoid dihydropteridine reductase	0.0004	0.5	0.5
Entamoeba histolytica	hypothetical protein	0.0004	0.5	0.5
Leishmania major	short chain dehydrogenase, putative	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	oxidoreductase	0.0004	0.5	0.5
Loa Loa (eye worm)	oxidoreductase	0.0004	0.5	0.5
Trichomonas vaginalis	short-chain dehydrogenases/reductase, putative	0.0004	0.5	0.5
Leishmania major	quinonoid dihydropteridine reductase	0.0004	0.5	0.5
Entamoeba histolytica	3-ketodihydrosphingosine reductase protein, putative	0.0004	0.5	0.5
Trypanosoma cruzi	short chain dehydrogenase/reductase, putative	0.0004	0.5	0.5
Loa Loa (eye worm)	oxidoreductase	0.0004	0.5	0.5
Trypanosoma cruzi	beta-ketoacyl-ACP reductase 2, putative	0.0004	0.5	0.5
Leishmania major	quinonoid dihydropteridine reductase	0.0004	0.5	0.5
Brugia malayi	Hypothetical oxidoreductase F56D1.5	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain dehydrogenase	0.0004	0.5	0.5
Giardia lamblia	Oxidoreductase, short chain dehydrogenase/reductase family	0.0004	0.5	0.5
Brugia malayi	Dehydrogenases, short chain protein 30	0.0004	0.5	0.5
Brugia malayi	3-hydroxyacyl-CoA dehydrogenase type II	0.0004	0.5	0.5
Toxoplasma gondii	oxidoreductase, putative	0.0004	0.5	0.5
Onchocerca volvulus	Dehydrogenase\/reductase SDR family member 13 homolog	0.0004	0.5	0.5
Echinococcus granulosus	Dehydrogenase:reductase SDR family	0.0004	0.5	0.5
Trichomonas vaginalis	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Toxoplasma gondii	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Brugia malayi	dehydrogenases, short chain protein 9	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Leishmania major	short chain dehydrogenase, putative	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain type oxidoreductase	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Trichomonas vaginalis	hydroxyacyl dehydrogenase, putative	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Echinococcus granulosus	retinol dehydrogenase 11	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Leishmania major	hypothetical protein, conserved	0.0004	0.5	0.5
Schistosoma mansoni	steroid dehydrogenase	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Brugia malayi	Dehydrogenases, short chain protein 2	0.0004	0.5	0.5
Giardia lamblia	Hypothetical protein	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Trypanosoma brucei	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Trichomonas vaginalis	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Toxoplasma gondii	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Trypanosoma cruzi	3-ketoacyl-CoA reductase, putative	0.0004	0.5	0.5
Loa Loa (eye worm)	dehydrogenase	0.0004	0.5	0.5
Echinococcus multilocularis	retinol dehydrogenase 11	0.0004	0.5	0.5
Echinococcus granulosus	oxidoreductase	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Trypanosoma brucei	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Toxoplasma gondii	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Mycobacterium tuberculosis	Decaprenylphosphoryl-D-2-keto erythro pentose reductase	0.0004	0.5	0.5
Trichomonas vaginalis	steroid dehydrogenase, putative	0.0004	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0004	0.5	0.5
Trypanosoma cruzi	NAD(P)-dependent oxidoreductase, putative	0.0004	0.5	0.5
Loa Loa (eye worm)	dehydrogenase	0.0004	0.5	0.5
Trichomonas vaginalis	short-chain dehydrogenase, putative	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable oxidoreductase	0.0004	0.5	0.5
Leishmania major	oxidoreductase-like protein	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Schistosoma mansoni	steroid dehydrogenase	0.0004	0.5	0.5
Leishmania major	hypothetical protein, conserved	0.0004	0.5	0.5
Mycobacterium leprae	Probable short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Echinococcus granulosus	carbonyl reductase 1	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0004	0.5	0.5
Echinococcus multilocularis	3 ketodihydrosphingosine reductase	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Schistosoma mansoni	oxidoreductase short chain dehydrogenase/reductase family	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Toxoplasma gondii	carbonyl reductase 1, putative	0.0004	0.5	0.5
Mycobacterium ulcerans	carveol-like dehydrogenase	0.0004	0.5	0.5
Mycobacterium leprae	Possible short-chain dehydrogenase EphD	0.0004	0.5	0.5
Echinococcus multilocularis	steroid dehydrogenase	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Echinococcus granulosus	hypothetical protein	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Mycobacterium ulcerans	oxidoreductase	0.0004	0.5	0.5
Echinococcus granulosus	carbonyl reductase 1	0.0004	0.5	0.5
Echinococcus multilocularis	epidermal retinal dehydrogenase 2	0.0004	0.5	0.5
Onchocerca volvulus		0.0004	0.5	0.5
Wolbachia endosymbiont of Brugia malayi	Short-chain alcohol dehydrogenase family enzyme	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Mycobacterium leprae	Probable oxidoreductase	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Mycobacterium tuberculosis	Probable oxidoreductase	0.0004	0.5	0.5
Echinococcus granulosus	retinol dehydrogenase 11	0.0004	0.5	0.5
Trypanosoma cruzi	short chain dehydrogenase, putative	0.0004	0.5	0.5
Trypanosoma brucei	oxidoreductase-like protein	0.0004	0.5	0.5
Schistosoma mansoni	short chain dehydrogenase	0.0004	0.5	0.5
Schistosoma mansoni	carbonyl reductase	0.0004	0.5	0.5
Leishmania major	quinonoid dihydropteridine reductase	0.0004	0.5	0.5
Leishmania major	quinonoid dihydropteridine reductase	0.0004	0.5	0.5
Mycobacterium ulcerans	dehydrogenase	0.0004	0.5	0.5
Mycobacterium ulcerans	short chain dehydrogenase	0.0004	0.5	0.5
Trypanosoma cruzi	hypothetical protein, conserved	0.0004	0.5	0.5
Mycobacterium tuberculosis	Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1	0.0004	0.5	0.5
Echinococcus granulosus	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0004	0.5	0.5
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0004	0.5	0.5
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0004	0.5	0.5

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2058845

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1660474