Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | cyclin D, putative | 0.005 | 0.0299 | 0.0656 |
Schistosoma mansoni | Cyclin fold protein | 0.005 | 0.0299 | 0.02 |
Trichomonas vaginalis | cyclins, putative | 0.005 | 0.0299 | 0.0656 |
Schistosoma mansoni | g1/s-specific cyclin C | 0.005 | 0.0299 | 0.02 |
Entamoeba histolytica | cyclin, domain containing protein | 0.005 | 0.0299 | 0.0823 |
Leishmania major | mitotic cyclin, putative | 0.005 | 0.0299 | 0.0516 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.004 | 0.004 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0374 | 0.0275 |
Onchocerca volvulus | Cyclin L homolog | 0.005 | 0.0299 | 0.1316 |
Trichomonas vaginalis | cyclins, putative | 0.0208 | 0.1607 | 0.7973 |
Brugia malayi | hypothetical protein | 0.0075 | 0.0507 | 0.0507 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0252 | 0.1969 | 0.1969 |
Giardia lamblia | Kinase, CMGC CLK | 0.0059 | 0.0372 | 0.1331 |
Brugia malayi | Protein kinase domain containing protein | 0.0059 | 0.0372 | 0.0372 |
Schistosoma mansoni | cyclin G2 | 0.005 | 0.0299 | 0.02 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0036 | 0.0182 | 0.0082 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.005 | 0.0299 | 0.0299 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.005 | 0.0299 | 0.0299 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0036 | 0.0182 | 0.0082 |
Giardia lamblia | Hypothetical protein | 0.005 | 0.0299 | 0.0823 |
Trichomonas vaginalis | cyclin D, putative | 0.0208 | 0.1607 | 0.7973 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.004 | 0.004 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0208 | 0.1607 | 0.1607 |
Echinococcus granulosus | cyclin G2 | 0.005 | 0.0299 | 0.02 |
Toxoplasma gondii | cell-cycle-associated protein kinase CLK, putative | 0.0059 | 0.0372 | 0.0152 |
Toxoplasma gondii | hypothetical protein | 0.0158 | 0.1191 | 0.1872 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.005 | 0.0299 | 0.0299 |
Schistosoma mansoni | camp-regulated phosphoprotein | 0.0165 | 0.1244 | 0.1154 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.004 | 0.004 |
Echinococcus granulosus | cyclin A3 4 | 0.005 | 0.0299 | 0.02 |
Brugia malayi | Dihydrofolate reductase | 0.1224 | 1 | 1 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.1224 | 1 | 1 |
Loa Loa (eye worm) | CYL-1 protein | 0.005 | 0.0299 | 0.0299 |
Trypanosoma brucei | cyclin dependent kinase-binding protein, putative | 0.005 | 0.0299 | 0.0516 |
Echinococcus granulosus | dual specificity protein kinase clk2 | 0.0059 | 0.0372 | 0.0273 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0299 | 0.0299 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0166 | 0.1252 | 0.7643 |
Echinococcus multilocularis | cyclin G2 | 0.005 | 0.0299 | 0.02 |
Schistosoma mansoni | cyclin G | 0.005 | 0.0299 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.1607 | 0.1607 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0101 | 0.0101 |
Trypanosoma brucei | mitotic cyclin | 0.005 | 0.0299 | 0.0516 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.0208 | 0.1607 | 0.1521 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.005 | 0.0299 | 0.0516 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.1969 | 1 |
Echinococcus multilocularis | cyclin B | 0.0208 | 0.1607 | 0.1521 |
Trypanosoma cruzi | cyclin 9, putative | 0.005 | 0.0299 | 0.0516 |
Trichomonas vaginalis | cyclins, putative | 0.0208 | 0.1607 | 0.7973 |
Echinococcus multilocularis | cyclin B3 1 | 0.0208 | 0.1607 | 0.1521 |
Echinococcus granulosus | cyclin y | 0.005 | 0.0299 | 0.02 |
Echinococcus multilocularis | oligomeric golgi complex subunit 3 | 0.005 | 0.0299 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0299 | 0.0299 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0059 | 0.0372 | 0.0661 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 0.0372 | 0.1061 |
Entamoeba histolytica | hypothetical protein | 0.005 | 0.0299 | 0.0823 |
Onchocerca volvulus | 0.005 | 0.0299 | 0.1316 | |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0036 | 0.0182 | 0.0283 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0208 | 0.1607 | 1 |
Leishmania major | cyclin | 0.0208 | 0.1607 | 0.3119 |
Onchocerca volvulus | Cyclin L homolog | 0.005 | 0.0299 | 0.1316 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.005 | 0.0299 | 0.0299 |
Trichomonas vaginalis | cyclin B, putative | 0.0208 | 0.1607 | 0.7973 |
Echinococcus granulosus | cyclin b3 | 0.0208 | 0.1607 | 0.1521 |
Echinococcus multilocularis | cyclins | 0.0208 | 0.1607 | 0.1521 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0101 | 0.0101 |
Brugia malayi | thymidylate synthase | 0.0159 | 0.1195 | 0.1195 |
Trichomonas vaginalis | cyclin B, putative | 0.005 | 0.0299 | 0.0656 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0374 | 0.0335 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0059 | 0.0372 | 0.0661 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.0182 | 0.0283 |
Echinococcus granulosus | camp regulated phosphoprotein | 0.0165 | 0.1244 | 0.1154 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0299 | 0.0656 |
Trypanosoma cruzi | mitotic cyclin, putative | 0.005 | 0.0299 | 0.0516 |
Trichomonas vaginalis | cyclin D, putative | 0.0208 | 0.1607 | 0.7973 |
Schistosoma mansoni | cyclin d | 0.005 | 0.0299 | 0.02 |
Trichomonas vaginalis | cyclin A, putative | 0.0208 | 0.1607 | 0.7973 |
Trypanosoma brucei | kinetoplastid kinetochore protein 10 | 0.0059 | 0.0372 | 0.0661 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0036 | 0.0182 | 0.0082 |
Echinococcus multilocularis | cyclins | 0.0208 | 0.1607 | 0.1521 |
Schistosoma mansoni | cyclins | 0.0208 | 0.1607 | 0.1521 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0299 | 0.0656 |
Echinococcus multilocularis | cyclins | 0.0208 | 0.1607 | 0.1521 |
Trypanosoma brucei | kinetoplastid kinetochore protein 19 | 0.0059 | 0.0372 | 0.0661 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.005 | 0.0299 | 0.02 |
Echinococcus multilocularis | dihydrofolate reductase | 0.1224 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.005 | 0.0299 | 0.0656 |
Echinococcus multilocularis | cyclin b3 | 0.0208 | 0.1607 | 0.1521 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0075 | 0.0507 | 0.093 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.1252 | 0.5987 |
Trichomonas vaginalis | cyclin B, putative | 0.0208 | 0.1607 | 0.7973 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0036 | 0.0182 | 0.0082 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.005 | 0.0299 | 0.0299 |
Echinococcus multilocularis | cAMP regulated phosphoprotein 19 | 0.0165 | 0.1244 | 0.1154 |
Brugia malayi | cyclin fold protein 1 variant b | 0.005 | 0.0299 | 0.0299 |
Echinococcus multilocularis | cyclin A3 4 | 0.005 | 0.0299 | 0.02 |
Echinococcus granulosus | cyclin t1 | 0.005 | 0.0299 | 0.02 |
Leishmania major | cyclin 9, putative | 0.005 | 0.0299 | 0.0516 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0299 | 0.0656 |
Leishmania major | protein kinase, putative | 0.0059 | 0.0372 | 0.0661 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.005 | 0.0299 | 0.02 |
Entamoeba histolytica | cyclin, domain containing protein | 0.005 | 0.0299 | 0.0823 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0208 | 0.1607 | 0.1607 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0374 | 0.0275 |
Trypanosoma brucei | cyclin 3 | 0.005 | 0.0299 | 0.0516 |
Trichomonas vaginalis | cyclin A, putative | 0.005 | 0.0299 | 0.0656 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0123 | 0.0123 |
Echinococcus granulosus | cyclin B | 0.0208 | 0.1607 | 0.1521 |
Echinococcus multilocularis | cyclin y | 0.005 | 0.0299 | 0.02 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.1969 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0299 | 0.0656 |
Echinococcus granulosus | Cyclin L1 | 0.005 | 0.0299 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.1607 | 0.1607 |
Echinococcus granulosus | cAMP regulated phosphoprotein 19 | 0.0165 | 0.1244 | 0.1154 |
Brugia malayi | hypothetical protein | 0.005 | 0.0299 | 0.0299 |
Plasmodium falciparum | cyclin | 0.0208 | 0.1607 | 0.2745 |
Entamoeba histolytica | cyclin, putative | 0.0208 | 0.1607 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0059 | 0.0372 | 0.0273 |
Echinococcus multilocularis | dual specificity protein kinase clk2 | 0.0059 | 0.0372 | 0.0273 |
Leishmania major | protein kinase, putative | 0.0059 | 0.0372 | 0.0661 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.1252 | 0.5987 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.005 | 0.0299 | 0.0299 |
Trichomonas vaginalis | cyclin B, putative | 0.0208 | 0.1607 | 0.7973 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0299 | 0.02 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0627 | 0.5063 | 1 |
Leishmania major | mitotic cyclin, putative | 0.005 | 0.0299 | 0.0516 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.0182 | 0.0283 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0101 | 0.0101 |
Trichomonas vaginalis | cyclin B, putative | 0.0208 | 0.1607 | 0.7973 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0368 | 0.0368 |
Trichomonas vaginalis | cyclins, putative | 0.005 | 0.0299 | 0.0656 |
Echinococcus multilocularis | thymidylate synthase | 0.0159 | 0.1195 | 0.1105 |
Echinococcus granulosus | cyclins | 0.0208 | 0.1607 | 0.1521 |
Echinococcus granulosus | cyclin y | 0.005 | 0.0299 | 0.02 |
Trypanosoma cruzi | mitotic cyclin, putative | 0.005 | 0.0299 | 0.0516 |
Schistosoma mansoni | camp-regulated phosphoprotein | 0.0165 | 0.1244 | 0.1154 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0208 | 0.1607 | 0.7973 |
Onchocerca volvulus | 0.0159 | 0.1195 | 0.7263 | |
Echinococcus granulosus | cdk5 and abl1 enzyme substrate 1 | 0.005 | 0.0299 | 0.02 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.005 | 0.0299 | 0.02 |
Entamoeba histolytica | cyclin family protein | 0.0208 | 0.1607 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.005 | 0.0299 | 0.0299 |
Giardia lamblia | Cyclin A | 0.0208 | 0.1607 | 1 |
Loa Loa (eye worm) | CMGC/CLK protein kinase | 0.0059 | 0.0372 | 0.0372 |
Trichomonas vaginalis | cyclin B3, putative | 0.005 | 0.0299 | 0.0656 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0208 | 0.1607 | 0.3119 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0159 | 0.1195 | 0.0853 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0101 | 0.0101 |
Echinococcus multilocularis | cyclin y | 0.005 | 0.0299 | 0.02 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0299 | 0.02 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0208 | 0.1607 | 0.3119 |
Echinococcus granulosus | cyclin | 0.005 | 0.0299 | 0.02 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0208 | 0.1607 | 0.1607 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.1969 | 1 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0036 | 0.0182 | 0.0082 |
Trichomonas vaginalis | cyclin B, putative | 0.0208 | 0.1607 | 0.7973 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0097 | 0.0097 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.1252 | 0.5987 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0627 | 0.5063 | 1 |
Echinococcus granulosus | cyclins | 0.005 | 0.0299 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0101 | 0.0101 |
Onchocerca volvulus | Protein CNPPD1 homolog | 0.005 | 0.0299 | 0.1316 |
Mycobacterium ulcerans | thymidylate synthase | 0.0159 | 0.1195 | 0.1159 |
Trypanosoma cruzi | cyclin 6, putative | 0.0208 | 0.1607 | 0.3119 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0123 | 0.0123 |
Schistosoma mansoni | cyclin l | 0.005 | 0.0299 | 0.02 |
Plasmodium falciparum | protein serine/threonine kinase-1 | 0.0059 | 0.0372 | 0.0152 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0252 | 0.1969 | 0.1969 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0075 | 0.0507 | 0.0139 |
Trichomonas vaginalis | cyclin B3, putative | 0.0208 | 0.1607 | 0.7973 |
Echinococcus granulosus | oligomeric golgi complex subunit 3 | 0.005 | 0.0299 | 0.02 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.005 | 0.0299 | 0.0299 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.005 | 0.0299 | 0.0299 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.0182 | 0.0283 |
Echinococcus granulosus | dihydrofolate reductase | 0.1224 | 1 | 1 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.1224 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0182 | 0.0182 |
Trichomonas vaginalis | cyclins, putative | 0.005 | 0.0299 | 0.0656 |
Entamoeba histolytica | cyclin C, putative | 0.005 | 0.0299 | 0.0823 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0627 | 0.5063 | 1 |
Echinococcus multilocularis | cyclins | 0.0208 | 0.1607 | 0.1521 |
Loa Loa (eye worm) | cyclin fold protein 1 variant b | 0.005 | 0.0299 | 0.0299 |
Echinococcus multilocularis | cyclins | 0.0208 | 0.1607 | 0.1521 |
Echinococcus multilocularis | cdk5 and abl1 enzyme substrate 1 | 0.005 | 0.0299 | 0.02 |
Giardia lamblia | Cyclin B-like protein | 0.005 | 0.0299 | 0.0823 |
Brugia malayi | cAMP-regulated phosphoprotein/endosulfine conserved region containing protein | 0.004 | 0.0216 | 0.0216 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.0208 | 0.1607 | 0.1521 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0174 | 0.1325 | 0.6399 |
Trichomonas vaginalis | cyclins, putative | 0.0208 | 0.1607 | 0.7973 |
Echinococcus multilocularis | cyclins | 0.0208 | 0.1607 | 0.1521 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.0374 | 0.0275 |
Echinococcus granulosus | cyclin G2 | 0.005 | 0.0299 | 0.02 |
Echinococcus granulosus | cyclins | 0.0208 | 0.1607 | 0.1521 |
Brugia malayi | hypothetical protein | 0.005 | 0.0299 | 0.0299 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0208 | 0.1607 | 0.3119 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0627 | 0.5063 | 1 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0627 | 0.5063 | 1 |
Echinococcus multilocularis | 0.0059 | 0.0368 | 0.027 | |
Trichomonas vaginalis | cyclins, putative | 0.0208 | 0.1607 | 0.7973 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.1969 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0174 | 0.1325 | 0.6399 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0216 | 0.0216 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0627 | 0.5063 | 1 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.1224 | 1 | 1 |
Entamoeba histolytica | cyclin, putative | 0.0208 | 0.1607 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.1252 | 0.5987 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.0374 | 0.0665 |
Giardia lamblia | Hypothetical protein | 0.0208 | 0.1607 | 1 |
Echinococcus granulosus | cyclins | 0.0208 | 0.1607 | 0.1521 |
Schistosoma mansoni | dihydrofolate reductase | 0.1224 | 1 | 1 |
Trypanosoma brucei | cyclin 9 | 0.005 | 0.0299 | 0.0516 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.005 | 0.0299 | 0.0299 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.1252 | 0.5987 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0075 | 0.0507 | 0.182 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.1252 | 0.5987 |
Echinococcus multilocularis | camp regulated phosphoprotein | 0.0165 | 0.1244 | 0.1154 |
Echinococcus granulosus | thymidylate synthase | 0.0159 | 0.1195 | 0.1105 |
Echinococcus multilocularis | cyclin t1 | 0.005 | 0.0299 | 0.02 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.004 | 0.004 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.1969 | 1 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0036 | 0.0182 | 0.0082 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.1969 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0019 | 0.004 | 0.004 |
Echinococcus multilocularis | cyclins | 0.0208 | 0.1607 | 0.1521 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0036 | 0.0182 | 0.0082 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.0374 | 0.0156 |
Echinococcus multilocularis | cyclin | 0.005 | 0.0299 | 0.02 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0159 | 0.1195 | 0.1105 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.0374 | 0.0275 |
Echinococcus granulosus | cyclins | 0.0208 | 0.1607 | 0.1521 |
Trichomonas vaginalis | cyclin B3, putative | 0.005 | 0.0299 | 0.0656 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0036 | 0.0182 | 0.0182 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0374 | 0.0335 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0166 | 0.1252 | 0.5987 |
Schistosoma mansoni | cyclin B3 | 0.0208 | 0.1607 | 0.1521 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.005 | 0.0299 | 0.0299 |
Loa Loa (eye worm) | cyclin C | 0.005 | 0.0299 | 0.0299 |
Giardia lamblia | Hypothetical protein | 0.005 | 0.0299 | 0.0823 |
Echinococcus multilocularis | cyclin G2 | 0.005 | 0.0299 | 0.02 |
Trypanosoma cruzi | cyclin, putative | 0.0208 | 0.1607 | 0.3119 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0059 | 0.0372 | 0.0273 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.1224 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0059 | 0.0368 | 0.027 |
Entamoeba histolytica | cyclin family protein | 0.0208 | 0.1607 | 1 |
Brugia malayi | Cyclin C | 0.005 | 0.0299 | 0.0299 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.005 | 0.0299 | 0.0299 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0059 | 0.0372 | 0.0661 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0059 | 0.0372 | 0.0661 |
Echinococcus granulosus | cyclins | 0.0208 | 0.1607 | 0.1521 |
Echinococcus multilocularis | Cyclin L1 | 0.005 | 0.0299 | 0.02 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0374 | 0.0335 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0036 | 0.0182 | 0.0082 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0208 | 0.1607 | 0.1607 |
Trichomonas vaginalis | cyclins, putative | 0.0208 | 0.1607 | 0.7973 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.005 | 0.0299 | 0.0299 |
Schistosoma mansoni | cyclin B | 0.0208 | 0.1607 | 0.1521 |
Schistosoma mansoni | camp-regulated phosphoprotein | 0.0165 | 0.1244 | 0.1154 |
Loa Loa (eye worm) | thymidylate synthase | 0.0159 | 0.1195 | 0.1195 |
Onchocerca volvulus | 0.0208 | 0.1607 | 1 | |
Trypanosoma cruzi | cyclin, putative | 0.0208 | 0.1607 | 0.3119 |
Chlamydia trachomatis | dihydrofolate reductase | 0.1224 | 1 | 0.5 |
Echinococcus granulosus | cyclin k | 0.005 | 0.0299 | 0.02 |
Giardia lamblia | Cyclin fold protein 1, putative | 0.005 | 0.0299 | 0.0823 |
Echinococcus granulosus | cyclin B3 1 | 0.0208 | 0.1607 | 0.1521 |
Plasmodium vivax | serine/threonine kinase-1, putative | 0.0059 | 0.0372 | 0.0152 |
Echinococcus multilocularis | cyclin k | 0.005 | 0.0299 | 0.02 |
Schistosoma mansoni | cyclin k | 0.005 | 0.0299 | 0.02 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | uM | Effective concentration that gives maximal stimulation of cyclic AMP production over the concentration range tested; b=Inactive | ChEMBL. | 6317860 |
IC50 (binding) | = 99.1 uM | Concentration of the compound that produces 50 % displacement of specific [3H]-spiroperidol binding to rat caudate membrane preparations. | ChEMBL. | 6317860 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.