Detailed information for compound 1662075

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 328.323 | Formula: C16H16N4O4
  • H donors: 3 H acceptors: 4 LogP: 1.92 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(cc1)N/N=C/1\CC[C@@H](n2c1ncc(c2=O)C(=O)O)C
  • InChi: 1S/C16H16N4O4/c1-9-2-7-13(19-18-10-3-5-11(21)6-4-10)14-17-8-12(16(23)24)15(22)20(9)14/h3-6,8-9,18,21H,2,7H2,1H3,(H,23,24)/b19-13+/t9-/m0/s1
  • InChiKey: NSPASPOEVWQKMJ-STJSCAKDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0067 0.0081
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.007 0.0236 0.0213
Echinococcus multilocularis somatostatin receptor 0.0066 0.0215 0.0214
Wolbachia endosymbiont of Brugia malayi thymidylate kinase 0.0156 0.0711 1
Echinococcus granulosus tm gpcr rhodopsin 0.0066 0.0215 0.0214
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0167 0.0131
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0037 0.0199
Echinococcus granulosus neuropeptide s receptor 0.0066 0.0215 0.0214
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Brugia malayi AKH receptor 0.0066 0.0215 0.1674
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.0186 0.0701
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0067 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0197 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0236 0.0213
Brugia malayi hypothetical protein 0.0066 0.0215 0.1674
Mycobacterium leprae probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) 0.0156 0.0711 0.9885
Loa Loa (eye worm) G-protein coupled receptor 0.0066 0.0215 0.1753
Schistosoma mansoni hypothetical protein 0.0353 0.18 0.179
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.0983 0.8044
Trypanosoma brucei thymidylate kinase, putative 0.0156 0.0711 0.0851
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.007 0.0236 0.0213
Onchocerca volvulus 0.0066 0.0215 0.1796
Echinococcus multilocularis neuropeptides capa receptor 0.0066 0.0215 0.0214
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0061 0.0186 0.0153
Echinococcus multilocularis GPCR, family 2 0.0034 0.0037 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0215 0.0203
Schistosoma mansoni neuropeptide F-like receptor 0.0066 0.0215 0.0203
Echinococcus multilocularis G protein coupled receptor 139 0.0066 0.0215 0.0214
Trichomonas vaginalis thymidylate kinase, putative 0.0156 0.0711 0.0786
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0115 0.0484 0.6453
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0241 0.1184 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0115 0.0484 0.6685
Trichomonas vaginalis ribonuclease H1, putative 0.0068 0.0225 0.02
Onchocerca volvulus 0.0066 0.0215 0.1796
Loa Loa (eye worm) hypothetical protein 0.0107 0.044 0.3593
Echinococcus granulosus sex peptide receptor 0.0066 0.0215 0.0214
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0107 0.044 0.3593
Treponema pallidum ribonuclease H (rnhA) 0.0068 0.0225 0.0735
Schistosoma mansoni lamin 0.0057 0.0163 0.015
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.0253 0.1989
Schistosoma mansoni inositol monophosphatase 0.0115 0.0484 0.0472
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0067 0.001
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0157 0.0718 0.0795
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0059 0.0046
Echinococcus multilocularis neuropeptide receptor A26 0.0066 0.0215 0.0214
Echinococcus multilocularis orexin receptor type 2 0.0066 0.0215 0.0214
Loa Loa (eye worm) G-protein coupled receptor 0.0066 0.0215 0.1753
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0013 0.0012
Onchocerca volvulus 0.0057 0.0163 0.1334
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0066 0.0215 0.1674
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0215 0.0203
Echinococcus multilocularis G-protein coupled receptor, putative 0.0066 0.0215 0.0214
Schistosoma mansoni hypothetical protein 0.0066 0.0215 0.0203
Loa Loa (eye worm) hypothetical protein 0.0039 0.0067 0.0541
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0037 0.0036
Trichomonas vaginalis inositol monophosphatase, putative 0.0115 0.0484 0.0513
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1702 0.9251 0.9251
Leishmania major cathepsin L-like protease 0.0063 0.0197 0.0167
Entamoeba histolytica Thymidylate kinase, putative 0.0156 0.0711 0.0786
Schistosoma mansoni biogenic amine receptor 0.0066 0.0215 0.0203
Echinococcus granulosus inositol monophosphatase 1 0.0115 0.0484 0.0483
Echinococcus multilocularis ribonuclease H1 0.0068 0.0225 0.0223
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Schistosoma mansoni hypothetical protein 0.0034 0.0037 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0197 0.0237
Trypanosoma cruzi thymidylate kinase, putative 0.0156 0.0711 0.0786
Brugia malayi Tachykinin-like peptides receptor 99D 0.0066 0.0215 0.1674
Schistosoma mansoni opsin-like receptor 0.0066 0.0215 0.0203
Onchocerca volvulus 0.0066 0.0215 0.1796
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0197 0.0237
Schistosoma mansoni hypothetical protein 0.0404 0.2085 0.2075
Plasmodium falciparum thymidylate kinase 0.0156 0.0711 0.9867
Echinococcus multilocularis neuropeptide receptor 0.0066 0.0215 0.0214
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0067 0.0066
Loa Loa (eye worm) hypothetical protein 0.0034 0.0037 0.0291
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0066 0.0215 0.0203
Mycobacterium tuberculosis Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) 0.0156 0.0711 0.5794
Echinococcus granulosus g protein coupled receptor 0.0066 0.0215 0.0214
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0143 0.0638 0.0637
Schistosoma mansoni phosphoglucomutase 0.0068 0.0225 0.0212
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0059 0.0058
Brugia malayi hypothetical protein 0.0075 0.0263 0.2073
Schistosoma mansoni amine GPCR 0.0066 0.0215 0.0203
Mycobacterium ulcerans thymidylate kinase 0.0156 0.0711 0.9885
Echinococcus multilocularis thyroid hormone receptor alpha 0.0162 0.0743 0.0742
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus granulosus 7TM GPCR rhodopsin 0.0066 0.0215 0.0214
Schistosoma mansoni growth hormone secretagogue receptor 0.0066 0.0215 0.0203
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0067 0.001
Brugia malayi hypothetical protein 0.0066 0.0215 0.1674
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus multilocularis allatostatin A receptor 0.0066 0.0215 0.0214
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0066 0.0215 0.1796
Echinococcus multilocularis neuropeptide Y receptor 0.0066 0.0215 0.0214
Brugia malayi putative neuropeptide receptor NPR1 0.0066 0.0215 0.1674
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0104 0.0091
Loa Loa (eye worm) thymidylate kinase 0.0156 0.0711 0.5816
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0061 0.0186 0.0137
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0146 0.0105
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0215 0.0203
Schistosoma mansoni neuropeptide receptor 0.0066 0.0215 0.0203
Giardia lamblia Glycogen phosphorylase 0.0106 0.0437 0.0426
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0157 0.0718 0.0795
Onchocerca volvulus 0.0057 0.0163 0.1334
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus multilocularis neuropeptide Y receptor 0.0066 0.0215 0.0214
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0066 0.0215 0.1753
Onchocerca volvulus 0.0066 0.0215 0.1796
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0197 0.0237
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0186 0.1127
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0066 0.0215 0.0214
Brugia malayi putative neuropeptide receptor 0.0066 0.0215 0.1674
Echinococcus granulosus somatostatin receptor 0.0066 0.0215 0.0214
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0197 0.0237
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus multilocularis g protein coupled receptor 0.0066 0.0215 0.0214
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0474
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0146 0.1888
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0474
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0075 0.0263 0.0246
Schistosoma mansoni hypothetical protein 0.0156 0.0711 0.0699
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus granulosus tachykinin peptides receptor 99D 0.0066 0.0215 0.0214
Giardia lamblia CDC8 0.0156 0.0711 0.0742
Echinococcus granulosus biogenic amine 5HT receptor 0.0066 0.0215 0.0214
Onchocerca volvulus 0.0066 0.0215 0.1796
Echinococcus granulosus neuropeptide receptor 0.0066 0.0215 0.0214
Echinococcus multilocularis musashi 0.0057 0.0163 0.0162
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0066 0.0215 0.0203
Schistosoma mansoni glycogen phosphorylase 0.0106 0.0437 0.0424
Echinococcus granulosus tm gpcr rhodopsin 0.0066 0.0215 0.0214
Brugia malayi RNase H family protein 0.0068 0.0225 0.1754
Echinococcus multilocularis lamin dm0 0.0057 0.0163 0.0162
Loa Loa (eye worm) hypothetical protein 0.0056 0.0157 0.1279
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0186 0.0185
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Schistosoma mansoni lipoxygenase 0.0058 0.017 0.0158
Schistosoma mansoni amine GPCR 0.0066 0.0215 0.0203
Echinococcus multilocularis neuropeptide receptor 0.0066 0.0215 0.0214
Schistosoma mansoni thymidylate kinase 0.0156 0.0711 0.0699
Echinococcus granulosus g-protein coupled receptor 0.0066 0.0215 0.0214
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0066 0.0215 0.0214
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0059 0.0046
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0157 0.0718 0.0706
Leishmania major cathepsin L-like protease 0.0063 0.0197 0.0167
Onchocerca volvulus 0.0233 0.1139 1
Brugia malayi neuropeptide F receptor 0.0066 0.0215 0.1674
Entamoeba histolytica hypothetical protein 0.007 0.0236 0.0213
Trichomonas vaginalis thymidine kinase, putative 0.1539 0.835 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus granulosus dna polymerase eta 0.0039 0.0067 0.0066
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0066 0.0215 0.0203
Echinococcus granulosus dna polymerase kappa 0.0039 0.0067 0.0066
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0104 0.0679
Mycobacterium ulcerans thymidylate synthase 0.0157 0.0718 1
Trypanosoma cruzi thymidylate kinase, putative 0.0156 0.0711 0.0786
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Entamoeba histolytica hypothetical protein 0.007 0.0236 0.0213
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.007 0.0236 0.0213
Onchocerca volvulus Putative thymidylate kinase 0.0156 0.0711 0.6197
Echinococcus multilocularis thymidine kinase 0.1837 1 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0066 0.0215 0.1753
Echinococcus multilocularis neuropeptides capa receptor 0.0066 0.0215 0.0214
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0215 0.0203
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0059 0.0058
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0067 0.0081
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0066 0.0215 0.1753
Trypanosoma cruzi UMP-CMP kinase, mitochondrial, putative 0.0061 0.0188 0.0156
Loa Loa (eye worm) neuropeptide F receptor 0.0066 0.0215 0.1753
Toxoplasma gondii ABC1 family protein 0.0038 0.0059 0.0656
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0067 0.0541
Brugia malayi hypothetical protein 0.0066 0.0215 0.1674
Schistosoma mansoni hypothetical protein 0.0073 0.0253 0.0241
Echinococcus granulosus neuropeptide Y receptor 0.0066 0.0215 0.0214
Brugia malayi GnHR receptor homolog 0.0066 0.0215 0.1674
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0059 0.0474
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0066 0.0215 0.0214
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0067 0.001
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.0484 0.0513
Brugia malayi thymidylate synthase 0.0157 0.0718 0.5839
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0157 0.0718 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0381 0.0369
Echinococcus multilocularis glycogen phosphorylase 0.0106 0.0437 0.0435
Loa Loa (eye worm) hypothetical protein 0.0029 0.0013 0.0094
Brugia malayi hypothetical protein 0.0066 0.0215 0.1674
Entamoeba histolytica glycogen phosphorylase, putative 0.0106 0.0437 0.0456
Echinococcus granulosus intermediate filament protein 0.0057 0.0163 0.0162
Loa Loa (eye worm) glycogen phosphorylase 0.0106 0.0437 0.3569
Brugia malayi hypothetical protein 0.0066 0.0215 0.1674
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0018 0.0136
Loa Loa (eye worm) thymidylate synthase 0.0157 0.0718 0.5878
Onchocerca volvulus 0.0066 0.0215 0.1796
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0066 0.0215 0.0214
Onchocerca volvulus 0.0051 0.013 0.1041
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0115 0.0484 0.5687
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0058 0.017 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0081
Onchocerca volvulus Ribonuclease H1 homolog 0.0068 0.0225 0.1881
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0067 0.0124
Trypanosoma brucei ingi protein (ORF1) 0.0077 0.0275 0.033
Echinococcus multilocularis thymidylate synthase 0.0157 0.0718 0.0717
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.0186 0.0153
Onchocerca volvulus 0.0157 0.0718 0.6265
Brugia malayi hypothetical protein 0.0248 0.1221 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0013 0.0012
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0186 0.0173
Trypanosoma brucei RNA helicase, putative 0.0404 0.2085 0.2497
Schistosoma mansoni hypothetical protein 0.0143 0.0638 0.0626
Loa Loa (eye worm) hypothetical protein 0.0073 0.0253 0.2065
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0186 0.0185
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0066 0.0215 0.0214
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0104 0.0054
Echinococcus multilocularis neuropeptide FF receptor 2 0.0066 0.0215 0.0214
Brugia malayi Dopamine receptor protein 1 0.0066 0.0215 0.1674
Entamoeba histolytica hypothetical protein 0.007 0.0236 0.0213
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0067 0.0451
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0067 0.0072
Echinococcus granulosus glycogen phosphorylase 0.0106 0.0437 0.0435
Echinococcus multilocularis glycogen phosphorylase 0.0106 0.0437 0.0435
Echinococcus multilocularis g-protein coupled receptor 0.0066 0.0215 0.0214
Echinococcus multilocularis g protein coupled receptor 0.0066 0.0215 0.0214
Trichomonas vaginalis thymidine kinase, putative 0.1539 0.835 1
Trypanosoma cruzi thymidine kinase, putative 0.1539 0.835 1
Brugia malayi Dopamine receptor protein 2 0.0066 0.0215 0.1674
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0066 0.0215 0.0203
Brugia malayi larval opioid receptor 0.0066 0.0215 0.1674
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0061 0.0186 0.0153
Echinococcus granulosus glycogen phosphorylase 0.0106 0.0437 0.0435
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0081
Giardia lamblia Hypothetical protein 0.007 0.0236 0.0194
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0067 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0215 0.0203
Onchocerca volvulus 0.0066 0.0215 0.1796
Brugia malayi Pre-SET motif family protein 0.0205 0.0983 0.8026
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.0484 0.0513
Leishmania major DNA polymerase kappa, putative 0.0039 0.0067 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Leishmania major ribonuclease H1, putative 0.0068 0.0225 0.02
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0163 0.1326
Schistosoma mansoni thymidine kinase 0.1837 1 1
Echinococcus multilocularis dna polymerase eta 0.0039 0.0067 0.0066
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Schistosoma mansoni phosphoglucomutase 0.0068 0.0225 0.0212
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0115 0.0484 0.0513
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0066 0.0215 0.0214
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Onchocerca volvulus 0.0038 0.0059 0.0411
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0197 0.0167
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0157 0.0718 0.5861
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0081
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0066 0.0215 0.0203
Trichomonas vaginalis thymidine kinase, putative 0.1539 0.835 1
Entamoeba histolytica thymidine kinase, putative 0.1539 0.835 1
Trypanosoma brucei unspecified product 0.0077 0.0275 0.033
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0066 0.0215 0.0203
Echinococcus granulosus thymidylate kinase 0.0156 0.0711 0.0709
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0123 0.0077
Schistosoma mansoni thymidylate kinase 0.0156 0.0711 0.0699
Brugia malayi follicle stimulating hormone receptor 0.0066 0.0215 0.1674
Schistosoma mansoni glycogen phosphorylase 0.0106 0.0437 0.0424
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0115 0.0484 0.0513
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0197 0.0237
Schistosoma mansoni alpha-1 adrenergic receptor 0.0066 0.0215 0.0203
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0474
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0067 0.001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0474
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0115 0.0484 0.0513
Leishmania major hypothetical protein, conserved 0.0054 0.0146 0.0105
Schistosoma mansoni inositol monophosphatase 0.0115 0.0484 0.0472
Trichomonas vaginalis glycogen phosphorylase, putative 0.0106 0.0437 0.0455
Schistosoma mansoni hypothetical protein 0.0066 0.0215 0.0203
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0061 0.0186 0.0223
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0263 0.0246
Echinococcus multilocularis NADH ubiquinone oxidoreductase 42 kDa subunit 0.007 0.0236 0.0235
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0107 0.044 0.3532
Entamoeba histolytica hypothetical protein 0.007 0.0236 0.0213
Brugia malayi Melatonin receptor type 1A 0.0066 0.0215 0.1674
Echinococcus granulosus hypothetical protein 0.0066 0.0215 0.0214
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0059 0.0071
Schistosoma mansoni opsin-like receptor 0.0066 0.0215 0.0203
Echinococcus granulosus G protein coupled receptor 139 0.0066 0.0215 0.0214
Leishmania major thymidine kinase, putative 0.1539 0.835 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0066 0.0215 0.0203
Trypanosoma brucei unspecified product 0.0039 0.0067 0.0081
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0059 0.0383
Echinococcus granulosus dro:myosuppressin receptor 0.0066 0.0215 0.0214
Brugia malayi Calcitonin receptor-like protein seb-1 0.0107 0.044 0.3532
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0104 0.0054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0197 0.0237
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0474
Onchocerca volvulus 0.0066 0.0215 0.1796
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0157 0.0718 1
Echinococcus multilocularis fmrfamide receptor 0.0066 0.0215 0.0214
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0474
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0067 0.0055
Treponema pallidum thymidylate kinase (tmk) 0.0156 0.0711 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0061 0.0186 0.1129
Giardia lamblia Deoxynucleoside kinase 0.1608 0.8734 1
Brugia malayi hypothetical protein 0.0066 0.0215 0.1674
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0066 0.0215 0.1753
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Schistosoma mansoni biogenic amine (5HT) receptor 0.0066 0.0215 0.0203
Brugia malayi exodeoxyribonuclease III family protein 0.0061 0.0186 0.1435
Echinococcus granulosus peptide allatostatin:somatostatin 0.0066 0.0215 0.0214
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0215 0.0203
Brugia malayi RNase H family protein 0.0068 0.0225 0.1754
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0157 0.0718 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0061 0.0186 0.1515
Loa Loa (eye worm) hypothetical protein 0.0054 0.0146 0.1186
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0066 0.0215 0.1674
Echinococcus multilocularis Glycosyl transferase, family 35 0.0106 0.0437 0.0435
Schistosoma mansoni amine GPCR 0.0066 0.0215 0.0203
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0081
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0037 0.0036
Schistosoma mansoni histamine h1 receptor 0.0066 0.0215 0.0203
Trypanosoma cruzi thymidine kinase, putative 0.1539 0.835 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0215 0.0203
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0067 0.0055
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0077 0.0275 0.033
Entamoeba histolytica hypothetical protein 0.007 0.0236 0.0213
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0104 0.0054
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0197 0.0167
Loa Loa (eye worm) beta-lactamase 0.0038 0.0059 0.0474
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus granulosus fmrfamide receptor 0.0066 0.0215 0.0214
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0018 0.0042
Echinococcus multilocularis thymidylate kinase 0.0156 0.0711 0.0709
Echinococcus granulosus thymidylate synthase 0.0157 0.0718 0.0717
Echinococcus granulosus 7tm_1 domain containing protein 0.0066 0.0215 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0081
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0381 0.305
Schistosoma mansoni hypothetical protein 0.0034 0.0037 0.0024
Schistosoma mansoni hypothetical protein 0.0034 0.0037 0.0024
Echinococcus granulosus g protein coupled receptor 0.0066 0.0215 0.0214
Echinococcus multilocularis thymidine kinase 0.1837 1 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0061 0.0186 0.0153
Brugia malayi ORL1-like opioid receptor 0.0066 0.0215 0.1674
Echinococcus multilocularis neuropeptide s receptor 0.0066 0.0215 0.0214
Entamoeba histolytica hypothetical protein 0.007 0.0236 0.0213
Onchocerca volvulus 0.0066 0.0215 0.1796
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Onchocerca volvulus 0.0066 0.0215 0.1796
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Giardia lamblia Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative 0.007 0.0236 0.0194
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0081
Trichomonas vaginalis set domain proteins, putative 0.0233 0.1139 0.1302
Onchocerca volvulus 0.0066 0.0215 0.1796
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0067 0.001
Schistosoma mansoni opsin-like receptor 0.0066 0.0215 0.0203
Onchocerca volvulus Glycogen phosphorylase homolog 0.0106 0.0437 0.3764
Plasmodium vivax thymidylate kinase, putative 0.0156 0.0711 0.9892
Brugia malayi hypothetical protein 0.0035 0.0041 0.0235
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Onchocerca volvulus 0.0066 0.0215 0.1796
Echinococcus multilocularis serotonin receptor 0.0066 0.0215 0.0214
Brugia malayi RNase H family protein 0.0068 0.0225 0.1754
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0067 0.0066
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0037 0.0199
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0066 0.0215 0.0203
Brugia malayi Dopamine receptor 0.0066 0.0215 0.1674
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0067 0.0451
Schistosoma mansoni thyroid hormone receptor 0.0162 0.0743 0.0731
Trypanosoma brucei thymidine kinase 0.1539 0.835 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.013 0.097
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.0484 0.058
Brugia malayi Serotonin receptor 0.0066 0.0215 0.1674
Schistosoma mansoni hypothetical protein 0.0164 0.0755 0.0743
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0157 0.0718 1
Chlamydia trachomatis thymidylate kinase 0.0156 0.0711 1
Trypanosoma cruzi UMP-CMP kinase, mitochondrial, putative 0.0061 0.0188 0.0156
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0066 0.0215 0.1674
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Schistosoma mansoni DNA polymerase eta 0.0039 0.0067 0.0055
Echinococcus multilocularis fmrfamide receptor 0.0066 0.0215 0.0214
Mycobacterium tuberculosis Hypothetical protein 0.0075 0.0263 0.1816
Schistosoma mansoni amine GPCR 0.0066 0.0215 0.0203
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0066 0.0215 0.0203
Brugia malayi hypothetical protein 0.0054 0.0146 0.1102
Trypanosoma cruzi ribonuclease H1, putative 0.0068 0.0225 0.02
Schistosoma mansoni intermediate filament proteins 0.0057 0.0163 0.015
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0067 0.0124
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0067 0.0066
Schistosoma mansoni hypothetical protein 0.0034 0.0037 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0197 0.0237
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0143 0.0638 0.0637
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0066 0.0215 0.0214
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0066 0.0215 0.1753
Echinococcus granulosus ribonuclease H1 0.0068 0.0225 0.0223
Schistosoma mansoni biogenic amine (5HT) receptor 0.0066 0.0215 0.0203
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0067 0.0081
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0066 0.0215 0.0214
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0197 0.0237
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0081
Brugia malayi G-protein coupled receptor 0.0066 0.0215 0.1674
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Giardia lamblia Thymidine kinase 0.1539 0.835 0.9557
Echinococcus granulosus lamin 0.0057 0.0163 0.0162
Brugia malayi hypothetical protein 0.0066 0.0215 0.1674
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0381 0.3116
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0186 0.1923
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0061 0.0186 0.0185
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0066 0.0215 0.0214
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0215 0.0203
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0104 0.0398
Brugia malayi Inositol-1 0.0115 0.0484 0.3903
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0236 0.0213
Echinococcus granulosus neuropeptide receptor A26 0.0066 0.0215 0.0214
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0381 0.0369
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Entamoeba histolytica hypothetical protein 0.007 0.0236 0.0213
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0081
Brugia malayi G-protein coupled receptor 0.0066 0.0215 0.1674
Echinococcus granulosus geminin 0.0353 0.18 0.1799
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0059 0.0656
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0197 0.0237
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0103 0.0418 0.3191
Echinococcus multilocularis transfer RNA-Ile 0.1837 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0066 0.0215 0.0214
Echinococcus multilocularis dro:myosuppressin receptor 0.0066 0.0215 0.0214
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0186 0.0153
Schistosoma mansoni myosin xvIII 0.0066 0.0215 0.0203
Schistosoma mansoni neuropeptide receptor 0.0066 0.0215 0.0203
Echinococcus granulosus neuropeptide FF receptor 2 0.0066 0.0215 0.0214
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0066 0.0215 0.0214
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Entamoeba histolytica hypothetical protein 0.007 0.0236 0.0213
Echinococcus multilocularis inositol monophosphatase 1 0.0115 0.0484 0.0483
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0146 0.1888
Schistosoma mansoni hypothetical protein 0.0353 0.18 0.179
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0037 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0236 0.0213
Echinococcus granulosus lamin dm0 0.0057 0.0163 0.0162
Schistosoma mansoni phosphoglucomutase 0.0068 0.0225 0.0212
Echinococcus multilocularis serotonin receptor 0.0066 0.0215 0.0214
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0066 0.0215 0.0214
Brugia malayi Deoxynucleoside kinase family protein 0.007 0.0236 0.1846
Loa Loa (eye worm) TYRA-2 protein 0.0066 0.0215 0.1753
Echinococcus granulosus Glycosyl transferase family 35 0.0106 0.0437 0.0435
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Brugia malayi RE15519p 0.0066 0.0215 0.1674
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0013 0.0012
Schistosoma mansoni thyroid hormone receptor 0.0162 0.0743 0.0731
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0275 0.033
Trichomonas vaginalis thymidylate kinase, putative 0.0156 0.0711 0.0786
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus granulosus g protein coupled receptor 0.0066 0.0215 0.0214
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0215 0.0203
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.007 0.0236 0.0223
Brugia malayi sulfakinin receptor protein 0.0066 0.0215 0.1674
Schistosoma mansoni hypothetical protein 0.0066 0.0215 0.0203
Schistosoma mansoni hypothetical protein 0.0051 0.013 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0236 0.0213
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0037 0.0291
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0197 0.0237
Trypanosoma brucei ribonuclease H1 0.0068 0.0225 0.0269
Schistosoma mansoni neuropeptide receptor 0.0066 0.0215 0.0203
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0157 0.0718 0.086
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0381 0.0369
Echinococcus multilocularis lamin 0.0057 0.0163 0.0162
Schistosoma mansoni amine GPCR 0.0066 0.0215 0.0203
Onchocerca volvulus Neuropeptide F receptor homolog 0.0066 0.0215 0.1796
Echinococcus granulosus neuropeptide receptor 0.0066 0.0215 0.0214
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0197 0.0167
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0066 0.0215 0.1674
Onchocerca volvulus 0.0066 0.0215 0.1796
Onchocerca volvulus 0.0066 0.0215 0.1796
Schistosoma mansoni ap endonuclease 0.0061 0.0186 0.0174
Schistosoma mansoni hypothetical protein 0.0066 0.0215 0.0203
Echinococcus granulosus GPCR family 2 0.0034 0.0037 0.0036
Schistosoma mansoni biogenic amine receptor 0.0066 0.0215 0.0203
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0381 0.038
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Echinococcus granulosus survival motor neuron protein 1 0.0248 0.1221 0.122
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.0186 0.0153
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0059 0.0058
Brugia malayi beta-lactamase family protein 0.0038 0.0059 0.0383
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0081
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0061 0.0186 0.0185
Toxoplasma gondii thymidylate kinase 0.0156 0.0711 0.9892
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0067 0.001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0061 0.0186 0.0153
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0066 0.0215 0.0203
Trypanosoma brucei ingi protein (ORF1) 0.0077 0.0275 0.033
Echinococcus granulosus NADH ubiquinone oxidoreductase 42 kDa subunit 0.007 0.0236 0.0235
Trypanosoma cruzi ribonuclease H1, putative 0.0068 0.0225 0.02
Echinococcus granulosus tm gpcr rhodopsin 0.0066 0.0215 0.0214
Loa Loa (eye worm) hypothetical protein 0.0057 0.0163 0.1326
Schistosoma mansoni lamin 0.0057 0.0163 0.015
Schistosoma mansoni neuropeptide receptor 0.0066 0.0215 0.0203
Schistosoma mansoni neuropeptide f receptor 76f 0.0066 0.0215 0.0203
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0066 0.0215 0.0214
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0215 0.0214
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0058 0.017 0.0169
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0037 0.0036
Brugia malayi hypothetical protein 0.0038 0.0059 0.0382
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0186 0.2453
Loa Loa (eye worm) inositol-1 0.0115 0.0484 0.3961
Loa Loa (eye worm) hypothetical protein 0.0248 0.1221 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0381 0.038
Trypanosoma brucei thymidylate kinase, putative 0.0156 0.0711 0.0851
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0066 0.0215 0.0214
Brugia malayi intermediate filament protein 0.0057 0.0163 0.1243
Onchocerca volvulus 0.0038 0.0059 0.0411
Echinococcus multilocularis sex peptide receptor 0.0066 0.0215 0.0214
Brugia malayi carbohydrate phosphorylase 0.0106 0.0437 0.3508
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0067 0.001
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0186 0.0173
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0067 0.0081
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.007 0.0236 0.0213
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0186 0.1923
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.0186 0.2457
Entamoeba histolytica hypothetical protein 0.007 0.0236 0.0213
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0381 0.038
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0066 0.0215 0.0203
Schistosoma mansoni adenoreceptor 0.0066 0.0215 0.0203
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0059 0.0058
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0066 0.0215 0.0214
Brugia malayi G protein-coupled receptor 0.0066 0.0215 0.1674
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0066 0.0215 0.1674
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Leishmania major thymidylate kinase-like protein 0.0156 0.0711 0.0786
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Loa Loa (eye worm) deoxynucleoside kinase 0.007 0.0236 0.1923
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0236 0.0213
Brugia malayi thymidylate kinase 0.0156 0.0711 0.5776
Onchocerca volvulus 0.0066 0.0215 0.1796
Brugia malayi Serotonin receptor 0.0066 0.0215 0.1674
Schistosoma mansoni survival motor neuron protein 0.0051 0.013 0.0117
Brugia malayi neuropeptide F receptor 0.0066 0.0215 0.1674
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0067 0.001
Trichomonas vaginalis glycogen phosphorylase, putative 0.0106 0.0437 0.0455
Echinococcus granulosus neuropeptides capa receptor 0.0066 0.0215 0.0214
Brugia malayi G protein-coupled receptor F59B2.13 0.0066 0.0215 0.1674
Echinococcus granulosus orexin receptor type 2 0.0066 0.0215 0.0214
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0066 0.0215 0.1753
Echinococcus granulosus serotonin receptor 0.0066 0.0215 0.0214
Toxoplasma gondii ribonuclease HI protein 0.0068 0.0225 0.3003
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Brugia malayi hypothetical protein 0.0066 0.0215 0.1674
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0163 0.1326
Giardia lamblia Hypothetical protein 0.007 0.0236 0.0194
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0066 0.0215 0.0214
Onchocerca volvulus 0.0066 0.0215 0.1796
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0066 0.0215 0.0203
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0186 0.1923
Schistosoma mansoni ap endonuclease 0.0061 0.0186 0.0174
Entamoeba histolytica glycogen phosphorylase, putative 0.0106 0.0437 0.0456
Echinococcus multilocularis g protein coupled receptor 0.0066 0.0215 0.0214
Schistosoma mansoni biogenic amine receptor 0.0066 0.0215 0.0203
Schistosoma mansoni neuropeptide F-like receptor 0.0066 0.0215 0.0203
Brugia malayi beta-lactamase family protein 0.0038 0.0059 0.0383
Schistosoma mansoni hypothetical protein 0.0038 0.0059 0.0046
Echinococcus granulosus biogenic amine 5HT receptor 0.0066 0.0215 0.0214
Loa Loa (eye worm) neuropeptide F receptor 0.0066 0.0215 0.1753
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0115 0.0484 0.0513
Onchocerca volvulus 0.0066 0.0215 0.1796
Brugia malayi hypothetical protein 0.0066 0.0215 0.1674
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0059 0.0046
Echinococcus granulosus allatostatin A receptor 0.0066 0.0215 0.0214
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0197 0.0167
Echinococcus granulosus neuropeptides capa receptor 0.0066 0.0215 0.0214
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0066 0.0215 0.0214
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0068 0.0225 0.0735
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0381 0.038
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0066 0.0215 0.0203
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0103 0.0418 0.5445
Echinococcus granulosus Thymidine kinase 2 mitochondrial 0.1837 1 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0066 0.0215 0.0214
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0061 0.0186 0.1927
Echinococcus granulosus thymidine kinase 0.1837 1 1
Leishmania major cathepsin L-like protease 0.0063 0.0197 0.0167
Onchocerca volvulus 0.0038 0.0059 0.0411
Toxoplasma gondii exonuclease III APE 0.0061 0.0186 0.2457
Brugia malayi hypothetical protein 0.0066 0.0215 0.1674
Leishmania major hypothetical protein, conserved 0.0061 0.0188 0.0156
Brugia malayi beta-lactamase 0.0038 0.0059 0.0383
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0146 0.0105
Giardia lamblia Ribonuclease H 0.0068 0.0225 0.0182
Echinococcus multilocularis geminin 0.0353 0.18 0.1799
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0066 0.0215 0.0214
Leishmania major DNA polymerase eta, putative 0.0039 0.0067 0.001
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0066 0.0215 0.0214
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0066 0.0215 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0067 0.0081
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0163 0.1243
Loa Loa (eye worm) hypothetical protein 0.0066 0.0215 0.1753
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0066 0.0215 0.0214
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0146 0.0175
Echinococcus multilocularis survival motor neuron protein 1 0.0248 0.1221 0.122

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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