Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.027 | 0.0767 |
Onchocerca volvulus | Peroxidasin homolog | 0.0222 | 0.3525 | 1 |
Schistosoma mansoni | peroxidasin | 0.0222 | 0.3525 | 0.3525 |
Onchocerca volvulus | 0.0222 | 0.3525 | 1 | |
Plasmodium falciparum | LCCL domain-containing protein | 0.0083 | 0.027 | 0.5 |
Onchocerca volvulus | 0.0222 | 0.3525 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Echinococcus multilocularis | RUN | 0.0083 | 0.027 | 0.027 |
Onchocerca volvulus | Peroxidasin homolog | 0.0222 | 0.3525 | 1 |
Brugia malayi | Peroxidasin | 0.0222 | 0.3525 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0083 | 0.027 | 0.5 |
Schistosoma mansoni | loxhd1 | 0.0083 | 0.027 | 0.027 |
Entamoeba histolytica | phospholipase D, putative | 0.012 | 0.1135 | 1 |
Schistosoma mansoni | rab6-interacting | 0.0083 | 0.027 | 0.027 |
Schistosoma mansoni | lipoxygenase | 0.0348 | 0.6485 | 0.6485 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0222 | 0.3525 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0222 | 0.3525 | 0.3525 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Onchocerca volvulus | 0.0222 | 0.3525 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.027 | 0.0767 |
Echinococcus multilocularis | phospholipase D1 | 0.012 | 0.1135 | 0.1135 |
Entamoeba histolytica | phospholipase D, putative | 0.012 | 0.1135 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0222 | 0.3525 | 1 |
Echinococcus granulosus | phospholipase D | 0.0106 | 0.0806 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0222 | 0.3525 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0083 | 0.027 | 0.027 |
Onchocerca volvulus | Dual oxidase homolog | 0.0222 | 0.3525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0222 | 0.3525 | 1 |
Schistosoma mansoni | peroxidasin | 0.0222 | 0.3525 | 0.3525 |
Brugia malayi | Animal haem peroxidase family protein | 0.0222 | 0.3525 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0083 | 0.027 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0684 | 0.194 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0083 | 0.027 | 0.027 |
Brugia malayi | Animal haem peroxidase family protein | 0.0222 | 0.3525 | 1 |
Brugia malayi | hypothetical protein | 0.0083 | 0.027 | 0.0767 |
Onchocerca volvulus | Peroxidase homolog | 0.0222 | 0.3525 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0498 | 1 | 1 |
Onchocerca volvulus | 0.0083 | 0.027 | 0.0767 | |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0222 | 0.3525 | 1 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0083 | 0.027 | 0.027 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.027 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0152 | 0.0433 |
Echinococcus granulosus | RUN | 0.0083 | 0.027 | 0.027 |
Echinococcus multilocularis | phospholipase D | 0.0106 | 0.0806 | 0.0806 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0072 | 0 | 0.5 |
Loa Loa (eye worm) | doublecortin family protein | 0.0083 | 0.027 | 0.0767 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0222 | 0.3525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0684 | 0.194 |
Brugia malayi | Phospholipase d protein 1 | 0.012 | 0.1135 | 0.322 |
Schistosoma mansoni | phospholipase D | 0.012 | 0.1135 | 0.1135 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0222 | 0.3525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0222 | 0.3525 | 1 |
Schistosoma mansoni | polycystin 1-related | 0.0083 | 0.027 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0222 | 0.3525 | 1 |
Brugia malayi | Doublecortin family protein | 0.0083 | 0.027 | 0.0767 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Brugia malayi | hypothetical protein | 0.0083 | 0.027 | 0.0767 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0498 | 1 | 1 |
Echinococcus granulosus | phospholipase D1 | 0.012 | 0.1135 | 0.1135 |
Brugia malayi | hypothetical protein | 0.0222 | 0.3525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0152 | 0.0433 |
Brugia malayi | Animal haem peroxidase family protein | 0.0222 | 0.3525 | 1 |
Onchocerca volvulus | 0.0083 | 0.027 | 0.0767 | |
Schistosoma mansoni | rab6-interacting | 0.0083 | 0.027 | 0.027 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0083 | 0.027 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0083 | 0.027 | 0.027 |
Echinococcus granulosus | peroxidasin | 0.0222 | 0.3525 | 0.3525 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.3525 | 1 |
Giardia lamblia | High cysteine protein | 0.0072 | 0 | 0.5 |
Onchocerca volvulus | Peroxidase homolog | 0.0222 | 0.3525 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.