Detailed information for compound 1664707

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 505.566 | Formula: C27H31N5O5
  • H donors: 5 H acceptors: 6 LogP: 3.95 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCOc1nc(C)c2c(c1)cc(o2)c1c(C)nc(nc1N[C@@H]1C[C@@H]([C@H]([C@H]1O)O)CO)Nc1ccccc1
  • InChi: 1S/C27H31N5O5/c1-4-36-21-12-16-11-20(37-25(16)15(3)28-21)22-14(2)29-27(30-18-8-6-5-7-9-18)32-26(22)31-19-10-17(13-33)23(34)24(19)35/h5-9,11-12,17,19,23-24,33-35H,4,10,13H2,1-3H3,(H2,29,30,31,32)/t17-,19-,23-,24+/m1/s1
  • InChiKey: VBHIGOAEZZTVTN-WRGFRKCQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0044 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0395 0.3711
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.1001 0.2016
Mycobacterium ulcerans carboxylesterase, LipT 0.0067 0.0674 1
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1298 0.2613
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0149 0.1155
Trichomonas vaginalis chromobox protein, putative 0.0041 0.033 0.303
Mycobacterium tuberculosis Carboxylesterase LipT 0.0067 0.0674 1
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0067 0.0674 0.1357
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0033 0.0233 0.0516
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0044 0.0089
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0266 0.2366
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0377 0.0758
Schistosoma mansoni BC026374 protein (S09 family) 0.0067 0.0674 0.1357
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0038 0.0038
Echinococcus granulosus sodium channel protein 0.0037 0.0278 0.0559
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0044 0.0089
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0678 0.1364
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0266 0.0589
Loa Loa (eye worm) hypothetical protein 0.0049 0.043 0.0866
Echinococcus multilocularis muscleblind protein 1 0.0145 0.168 0.168
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0093 0.1001 0.2016
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0044 0.0097
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Schistosoma mansoni gliotactin 0.0067 0.0674 0.1357
Onchocerca volvulus 0.0067 0.0674 0.6074
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0089
Brugia malayi serine/threonine-protein kinase plk-2 0.0093 0.1001 0.2016
Schistosoma mansoni chromobox protein 0.0068 0.0678 0.1364
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0168 0.2973
Echinococcus multilocularis acetylcholinesterase 0.0399 0.4967 0.4967
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0044 0.0097
Loa Loa (eye worm) hypothetical protein 0.0067 0.0674 0.1357
Echinococcus granulosus BC026374 protein S09 family 0.0067 0.0674 0.1357
Trypanosoma brucei unspecified product 0.0019 0.0044 0.0097
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0312 0.0312
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.1001 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0168 0.0338
Brugia malayi jmjC domain containing protein 0.0034 0.0245 0.0493
Schistosoma mansoni acetylcholinesterase 0.0067 0.0674 0.1357
Loa Loa (eye worm) acetylcholinesterase 1 0.0399 0.4967 1
Brugia malayi Inositol-1 0.0036 0.0266 0.0535
Loa Loa (eye worm) hypothetical protein 0.0149 0.1724 0.3471
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0038 0.0084
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0168 0.2973
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0093 0.1001 0.2016
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0044 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1001 1
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0565 1
Plasmodium falciparum phd finger protein, putative 0.0028 0.0168 0.7217
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0377 0.0758
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0044 0.0653
Leishmania major C-8 sterol isomerase-like protein 0.0364 0.4514 1
Echinococcus multilocularis BC026374 protein (S09 family) 0.0067 0.0674 0.0674
Loa Loa (eye worm) inositol-1 0.0036 0.0266 0.0535
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.041 0.0825
Giardia lamblia PHD finger protein 15 0.0028 0.0168 0.1351
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0266 0.0589
Brugia malayi Carboxylesterase family protein 0.0067 0.0674 0.1357
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0038 0.0084
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0038 0.0076
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0093 0.1001 0.2218
Echinococcus multilocularis geminin 0.0169 0.1983 0.1983
Echinococcus granulosus acetylcholinesterase 0.0399 0.4967 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0168 0.0168
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1001 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0377 0.0758
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0037 0.0278 0.0559
Loa Loa (eye worm) carboxylesterase 0.0067 0.0674 0.1357
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0245 0.0245
Brugia malayi Latrophilin receptor protein 2 0.0047 0.041 0.0825
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.041 0.041
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0044 0.0089
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0399 0.4967 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0044 0.0064
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0217 0.5
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0565 0.1137
Loa Loa (eye worm) hypothetical protein 0.0186 0.221 0.445
Giardia lamblia DINP protein human, muc B family 0.0019 0.0044 0.0064
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0565 0.1137
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0067 0.0674 1
Loa Loa (eye worm) hypothetical protein 0.0145 0.168 0.3382
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.041 0.0825
Echinococcus granulosus geminin 0.0169 0.1983 0.3993
Toxoplasma gondii Erv1 / Alr family protein 0.0033 0.0233 0.412
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Schistosoma mansoni hypothetical protein 0.0028 0.0168 0.0338
Loa Loa (eye worm) hypothetical protein 0.0067 0.0674 0.1357
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0044 0.0064
Schistosoma mansoni inositol monophosphatase 0.0036 0.0266 0.0535
Echinococcus granulosus GPCR family 2 0.0047 0.041 0.0825
Echinococcus multilocularis chromobox protein 1 0.0068 0.0678 0.0678
Echinococcus granulosus chromobox protein 1 0.0068 0.0678 0.1364
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0266 0.2366
Leishmania major DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0245 0.0493
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.1724 0.3471
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0565 0.8285
Brugia malayi MH2 domain containing protein 0.0116 0.1298 0.2613
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0266 0.0589
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0245 0.0493
Echinococcus multilocularis sodium channel protein 0.0037 0.0278 0.0278
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0266 0.2366
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0266 0.0535
Loa Loa (eye worm) hypothetical protein 0.0067 0.0674 0.1357
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0266 0.0589
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0678 0.664
Schistosoma mansoni inositol monophosphatase 0.0036 0.0266 0.0535
Echinococcus multilocularis carboxylesterase 5A 0.0399 0.4967 0.4967
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0266 1
Schistosoma mansoni hypothetical protein 0.0047 0.041 0.0825
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1298 0.2613
Echinococcus multilocularis muscleblind protein 0.0145 0.168 0.168
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.041 0.0825
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0168 0.0338
Loa Loa (eye worm) hypothetical protein 0.0067 0.0674 0.1357
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0044 0.0097
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0067 0.0674 0.1357
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0038 0.0076
Schistosoma mansoni hypothetical protein 0.0047 0.041 0.0825
Toxoplasma gondii exonuclease III APE 0.0018 0.0038 0.067
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0038 0.1625
Schistosoma mansoni neuroligin 3 (S09 family) 0.0067 0.0674 0.1357
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0755 0.1521
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0067 0.0674 0.1357
Loa Loa (eye worm) hypothetical protein 0.0145 0.168 0.3382
Schistosoma mansoni kinase 0.0047 0.0411 0.0828
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0565 0.1137
Echinococcus multilocularis para nitrobenzyl esterase 0.0067 0.0674 0.0674
Onchocerca volvulus 0.0067 0.0674 0.6074
Brugia malayi Carboxylesterase family protein 0.0067 0.0674 0.1357
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0377 0.0758
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0037 0.0278 0.0616
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0044 0.0097
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0292 0.1494
Schistosoma mansoni hypothetical protein 0.0169 0.1983 0.3993
Echinococcus multilocularis dna polymerase eta 0.0019 0.0044 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0292 0.2643
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0033 0.0233 1
Echinococcus granulosus para nitrobenzyl esterase 0.0067 0.0674 0.1357
Brugia malayi Muscleblind-like protein 0.0145 0.168 0.3382
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0399 0.4967 1
Trypanosoma brucei C-8 sterol isomerase, putative 0.0364 0.4514 1
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0033 0.0233 0.0233
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0067 0.0674 0.6604
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0044 0.0097
Echinococcus granulosus acetylcholinesterase 0.0399 0.4967 1
Toxoplasma gondii Erv1 / Alr family protein 0.0033 0.0233 0.412
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0395 0.3711
Trypanosoma brucei polo-like protein kinase 0.0093 0.1001 0.2218
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0033 0.0233 0.0516
Echinococcus multilocularis GPCR, family 2 0.0047 0.041 0.041
Echinococcus granulosus neuroligin 0.0067 0.0674 0.1357
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0093 0.1001 0.1001
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1001 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0266 0.3583
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0565 0.8381
Brugia malayi PHD-finger family protein 0.0028 0.0168 0.0338
Onchocerca volvulus 0.0067 0.0674 0.6074
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.041 0.041
Echinococcus multilocularis neuroligin 0.0067 0.0674 0.0674
Loa Loa (eye worm) hypothetical protein 0.0028 0.0168 0.0338
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0565 0.8285
Echinococcus granulosus dna polymerase kappa 0.0019 0.0044 0.0089
Schistosoma mansoni ap endonuclease 0.0018 0.0038 0.0076
Loa Loa (eye worm) hypothetical protein 0.0067 0.0674 0.1357
Onchocerca volvulus 0.0067 0.0674 0.6074
Echinococcus granulosus carboxylesterase 5A 0.0399 0.4967 1
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0312 0.0627
Trichomonas vaginalis chromobox protein, putative 0.0041 0.033 0.303
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0217 0.3221
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0245 0.0493
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0377 0.0377
Leishmania major hypothetical protein, conserved 0.0033 0.0233 0.0516
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0038 0.0084
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0067 0.0674 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0067 0.0674 0.1357
Echinococcus granulosus chromobox protein 1 0.0068 0.0678 0.1364
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0044 0.0097
Giardia lamblia Kinase, PLK 0.0093 0.1001 1
Echinococcus granulosus dna polymerase eta 0.0019 0.0044 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0038 0.0561
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0038 0.0084
Brugia malayi Carboxylesterase family protein 0.0399 0.4967 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.1002 0.2018
Schistosoma mansoni hypothetical protein 0.0169 0.1983 0.3993
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0558 0.1124
Brugia malayi Carboxylesterase family protein 0.0067 0.0674 0.1357
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0033 0.0233 0.0469
Brugia malayi Carboxylesterase family protein 0.0399 0.4967 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.041 0.0825
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.1116 0.2246
Schistosoma mansoni chromobox protein 0.0068 0.0678 0.1364
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.1724 0.3471
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0038 0.5
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.033 0.1942
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0044 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Echinococcus multilocularis peregrin 0.0028 0.0168 0.0168
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1001 1
Echinococcus multilocularis chromobox protein 1 0.0068 0.0678 0.0678
Echinococcus granulosus lysine specific demethylase 5A 0.0034 0.0245 0.0493
Onchocerca volvulus 0.003 0.0186 0.0221
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0377 0.0758
Leishmania major DNA polymerase eta, putative 0.0019 0.0044 0.0097
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0364 0.4514 0.9089
Loa Loa (eye worm) carboxylesterase 0.0067 0.0674 0.1357
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.1001 0.2218
Echinococcus multilocularis acetylcholinesterase 0.0399 0.4967 0.4967
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0149 0.1155
Brugia malayi hypothetical protein 0.0067 0.0674 0.1357
Echinococcus granulosus peregrin 0.0028 0.0168 0.0338
Brugia malayi jmjC domain containing protein 0.0093 0.1002 0.2018
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0565 0.1251
Loa Loa (eye worm) hypothetical protein 0.0067 0.0674 0.1357
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0565 0.0565
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0044 0.0653
Loa Loa (eye worm) hypothetical protein 0.0102 0.1116 0.2246
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0038 0.0292 0.0589
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0266 0.2366
Schistosoma mansoni hypothetical protein 0.0102 0.1116 0.2246
Schistosoma mansoni ap endonuclease 0.0018 0.0038 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Brugia malayi Augmenter of liver regeneration 0.0033 0.0233 0.0469
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0565 0.8285
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0377 0.0758
Schistosoma mansoni hypothetical protein 0.0047 0.041 0.0825
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0044 0.0064
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.041 0.0825
Brugia malayi Bromodomain containing protein 0.0028 0.0168 0.0338
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.1001 0.2218
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0678 0.664
Onchocerca volvulus 0.0067 0.0674 0.6074
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0067 0.0674 0.0674
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1001 1
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0038 0.0076
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0364 0.4514 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0038 0.1625
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0266 0.0266
Loa Loa (eye worm) hypothetical protein 0.0067 0.0674 0.1357
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1001 1
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0292 0.2643
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0044 0.0089
Brugia malayi Heterochromatin protein 1 0.0068 0.0678 0.1364
Loa Loa (eye worm) hypothetical protein 0.0364 0.4514 0.9089
Loa Loa (eye worm) hypothetical protein 0.0399 0.4967 1
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0033 0.0233 1
Loa Loa (eye worm) carboxylesterase 0.0399 0.4967 1
Brugia malayi chromobox protein homolog 3 0.0038 0.0292 0.0589
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1001 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0186 0.0375
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0168 0.0338
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Onchocerca volvulus Serine\/threonine kinase homolog 0.0093 0.1001 1
Schistosoma mansoni hypothetical protein 0.0047 0.041 0.0825
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0377 0.0377
Schistosoma mansoni DNA polymerase eta 0.0019 0.0044 0.0089
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0266 0.4705
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0044 0.0089
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Loa Loa (eye worm) hepatopoietin HPO2 0.0033 0.0233 0.0469
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0033 0.0233 0.0516
Echinococcus granulosus muscleblind protein 0.0145 0.168 0.3382
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.1724 0.3471
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0033 0.0233 0.0516
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Brugia malayi Carboxylesterase family protein 0.0067 0.0674 0.1357
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0377 0.0758
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0044 0.0097
Trichomonas vaginalis spcc417.12 protein, putative 0.0067 0.0674 0.6604
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0168 0.7217
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.1002 0.1002

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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