Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | vivapain-2 | 0.1413 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1413 | 0.4176 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2326 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0966 | 0.1329 | 0.1329 |
Loa Loa (eye worm) | hypothetical protein | 0.2326 | 1 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1413 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.1413 | 0.4176 | 1 | |
Leishmania major | cysteine peptidase A (CPA) | 0.1413 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1413 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.1413 | 0.4176 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1413 | 0.4176 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1413 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1413 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.1413 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1413 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1413 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1413 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0935 | 0.1126 | 0.1126 |
Leishmania major | cathepsin L-like protease | 0.1413 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1413 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.1413 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0966 | 0.1329 | 0.0228 |
Echinococcus multilocularis | cathepsin b | 0.2326 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.1413 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.1413 | 0.4176 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1413 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1413 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.1413 | 0.4176 | 1 | |
Leishmania major | cathepsin L-like protease | 0.1413 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1413 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.1413 | 0.4176 | 1 | |
Loa Loa (eye worm) | cysteine protease | 0.1413 | 0.4176 | 0.3437 |
Toxoplasma gondii | cathepsin CPL | 0.1413 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1413 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0966 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0935 | 0.1126 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0935 | 0.1126 | 0.2697 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1413 | 0.4176 | 0.4176 |
Echinococcus granulosus | cathepsin l1 | 0.0966 | 0.1329 | 0.1329 |
Leishmania major | cathepsin L-like protease | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0935 | 0.1126 | 0.2697 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0966 | 0.1329 | 0.3182 |
Onchocerca volvulus | 0.1413 | 0.4176 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1413 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1413 | 0.4176 | 1 |
Plasmodium vivax | vivapain-2 | 0.1413 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1413 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0935 | 0.1126 | 0.1126 |
Onchocerca volvulus | 0.1413 | 0.4176 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1413 | 0.4176 | 0.4176 |
Echinococcus multilocularis | cysteine protease | 0.1413 | 0.4176 | 0.4176 |
Leishmania major | cathepsin L-like protease | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0966 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1413 | 0.4176 | 0.3437 |
Echinococcus granulosus | cathepsin l1 | 0.1413 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2326 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2326 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0935 | 0.1126 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2326 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1413 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1413 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1413 | 0.4176 | 0.4176 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1413 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2326 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1413 | 0.4176 | 0.4176 |
Echinococcus granulosus | cathepsin b | 0.2326 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2326 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1413 | 0.4176 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0966 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0966 | 0.1329 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Onchocerca volvulus | 0.1413 | 0.4176 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1413 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | hypothetical protein | 0.0966 | 0.1329 | 0.0228 |
Onchocerca volvulus | Cathepsin L homolog | 0.1413 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0966 | 0.1329 | 0.1329 |
Leishmania major | cathepsin L-like protease | 0.1413 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1413 | 0.4176 | 0.4176 |
Giardia lamblia | Cathepsin B precursor | 0.0935 | 0.1126 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.1413 | 0.4176 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.1413 | 0.4176 | 0.3437 |
Echinococcus granulosus | cathepsin b | 0.2326 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1413 | 0.4176 | 1 |
Echinococcus multilocularis | cysteine protease | 0.1413 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.1413 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.1413 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1413 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1413 | 0.4176 | 1 |
Loa Loa (eye worm) | fibroinase | 0.1413 | 0.4176 | 0.3437 |
Loa Loa (eye worm) | hypothetical protein | 0.0966 | 0.1329 | 0.0228 |
Loa Loa (eye worm) | hypothetical protein | 0.1413 | 0.4176 | 0.3437 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1413 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0966 | 0.1329 | 0.1329 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0966 | 0.1329 | 0.3182 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1413 | 0.4176 | 0.3437 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1413 | 0.4176 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.