Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0165 | 0.4923 | 1 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0128 | 0.357 | 0.7224 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0128 | 0.357 | 0.7224 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.0079 | 0.1777 | 0.3546 |
Brugia malayi | proteasome subunit beta type 2 | 0.0079 | 0.1777 | 0.3546 |
Echinococcus granulosus | Proteasome subunit alpha type 7 | 0.0032 | 0.0048 | 0.0048 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0079 | 0.1777 | 0.3546 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0128 | 0.357 | 0.7224 |
Echinococcus granulosus | proteasome subunit beta t family | 0.0032 | 0.0048 | 0.0048 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0128 | 0.357 | 0.7224 |
Loa Loa (eye worm) | proteasome subunit alpha type 7-1 | 0.0032 | 0.0048 | 0.0098 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0079 | 0.1777 | 0.1777 |
Echinococcus granulosus | proteasome subunit beta type 7 | 0.0032 | 0.0048 | 0.0048 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0165 | 0.4923 | 0.4923 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.0079 | 0.1777 | 0.3546 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0032 | 0.0048 | 0.0098 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.0079 | 0.1777 | 0.3546 |
Echinococcus multilocularis | subfamily T1A non peptidase ue | 0.0032 | 0.0048 | 0.0048 |
Echinococcus multilocularis | proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta | 0.0032 | 0.0048 | 0.0048 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0128 | 0.357 | 0.7224 |
Echinococcus multilocularis | Proteasome, subunit alpha beta | 0.0032 | 0.0048 | 0.0048 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0128 | 0.357 | 0.7224 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0079 | 0.1777 | 0.3546 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0165 | 0.4923 | 1 |
Echinococcus multilocularis | proteasome subunit alpha type 2 | 0.0032 | 0.0048 | 0.0048 |
Echinococcus granulosus | proteasome subunit alpha type 2 | 0.0032 | 0.0048 | 0.0048 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0128 | 0.357 | 0.7224 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0165 | 0.4923 | 1 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0165 | 0.4923 | 1 |
Echinococcus granulosus | proteasome prosome macropain | 0.0165 | 0.4923 | 0.4923 |
Loa Loa (eye worm) | proteasome subunit alpha type 2 | 0.0032 | 0.0048 | 0.0098 |
Echinococcus granulosus | proteasome prosome macropain subunit beta type | 0.0032 | 0.0048 | 0.0048 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.0079 | 0.1777 | 0.3546 |
Echinococcus multilocularis | proteasome (prosome macropain) subunit alpha | 0.0032 | 0.0048 | 0.0048 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0128 | 0.357 | 0.357 |
Loa Loa (eye worm) | 20S proteasome alpha5 subunit | 0.0032 | 0.0048 | 0.0098 |
Trypanosoma cruzi | 20S proteasome subunit | 0.0079 | 0.1777 | 0.3546 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0128 | 0.357 | 0.7224 |
Loa Loa (eye worm) | proteasome subunit alpha type 3 | 0.0032 | 0.0048 | 0.0098 |
Mycobacterium ulcerans | proteasome PrcB | 0.0165 | 0.4923 | 1 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0165 | 0.4923 | 1 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0079 | 0.1777 | 0.3546 |
Echinococcus multilocularis | proteasome subunit beta type 7 | 0.0032 | 0.0048 | 0.0048 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0032 | 0.0048 | 0.0098 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0165 | 0.4923 | 1 |
Echinococcus multilocularis | proteasome subunit alpha type 6 | 0.0032 | 0.0048 | 0.0048 |
Onchocerca volvulus | Notchless protein homolog | 0.0032 | 0.0048 | 0.5 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.0079 | 0.1777 | 0.3546 |
Echinococcus multilocularis | proteasome (prosome macropain) subunit beta type | 0.0032 | 0.0048 | 0.0048 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0165 | 0.4923 | 1 |
Echinococcus multilocularis | 20S proteasome subunit alpha 6 | 0.0032 | 0.0048 | 0.0048 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0079 | 0.1777 | 0.1777 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0128 | 0.357 | 0.357 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0128 | 0.357 | 0.7224 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0032 | 0.0048 | 0.0098 |
Echinococcus granulosus | Proteasome subunit alpha beta | 0.0032 | 0.0048 | 0.0048 |
Loa Loa (eye worm) | proteasome subunit alpha type 1 | 0.0032 | 0.0048 | 0.0098 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0165 | 0.4923 | 1 |
Echinococcus multilocularis | proteasome subunit beta type 6 | 0.0032 | 0.0048 | 0.0048 |
Echinococcus granulosus | proteasome subunit alpha type 6 | 0.0032 | 0.0048 | 0.0048 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0128 | 0.357 | 0.7224 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0165 | 0.4923 | 1 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0032 | 0.0048 | 0.0048 |
Giardia lamblia | Proteasome subunit beta type 2 | 0.0079 | 0.1777 | 0.3546 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0079 | 0.1777 | 0.3546 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0128 | 0.357 | 0.7251 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0079 | 0.1777 | 0.3609 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0303 | 1 | 1 |
Echinococcus granulosus | 20S proteasome subunit alpha 6 | 0.0032 | 0.0048 | 0.0048 |
Loa Loa (eye worm) | PAS-3 protein | 0.0032 | 0.0048 | 0.0098 |
Loa Loa (eye worm) | proteasome subunit beta type 3 | 0.0032 | 0.0048 | 0.0098 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0128 | 0.357 | 0.7224 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0032 | 0.0048 | 0.0048 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0032 | 0.0048 | 0.0048 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.0079 | 0.1777 | 0.3546 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0165 | 0.4923 | 1 |
Echinococcus granulosus | proteasome subunit beta type 6 | 0.0032 | 0.0048 | 0.0048 |
Echinococcus granulosus | proteasome prosome macropain subunit alpha | 0.0032 | 0.0048 | 0.0048 |
Loa Loa (eye worm) | proteasome subunit alpha type 6 | 0.0032 | 0.0048 | 0.0098 |
Brugia malayi | proteasome subunit beta type 1 | 0.0128 | 0.357 | 0.7224 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0079 | 0.1777 | 0.3546 |
Echinococcus granulosus | subfamily T1A non peptidase ue | 0.0032 | 0.0048 | 0.0048 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent protease peptidase subunit | 0.0032 | 0.0048 | 0.5 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0165 | 0.4923 | 1 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0165 | 0.4923 | 1 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0165 | 0.4923 | 1 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0165 | 0.4923 | 1 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0165 | 0.4923 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.