Detailed information for compound 16750

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 341.858 | Formula: C19H22ClN4+
  • H donors: 1 H acceptors: 1 LogP: 3.52 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)N1CC[NH+](CC1)Cc1cnn2c1cccc2C
  • InChi: 1S/C19H21ClN4/c1-15-3-2-4-19-16(13-21-24(15)19)14-22-9-11-23(12-10-22)18-7-5-17(20)6-8-18/h2-8,13H,9-12,14H2,1H3/p+1
  • InChiKey: UIYATCKYXWPCQG-UHFFFAOYSA-O  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0011 0.0015 0.0015
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0146 0.1056
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0057 0.0202 0.0202
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Brugia malayi hypothetical protein 0.0033 0.0103 0.0103
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0042 0.0141 0.0141
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.0101 0.0101
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0242 0.1754
Schistosoma mansoni ferritin 0.001 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0023 0.0063 0.0063
Brugia malayi conserved hypotetical protein 0.0027 0.0078 0.0078
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.2437 0.9989 1
Brugia malayi Hsp90 protein 0.0016 0.0032 0.0032
Echinococcus granulosus neuropeptide receptor A26 0.0011 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0402 0.1621 0.1621
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0032 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0146 0.0146
Echinococcus granulosus neuropeptides capa receptor 0.0011 0.0015 0.0015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.001 0.0011 0.0011
Echinococcus granulosus serine:threonine protein kinase SMG1 0.001 0.0009 0.0009
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0017 0.0017
Brugia malayi larval opioid receptor 0.0011 0.0015 0.0015
Onchocerca volvulus Bile acid receptor homolog 0.0057 0.0202 0.1462
Trypanosoma cruzi DNA polymerase eta, putative 0.0017 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0402 0.1621 0.1621
Schistosoma mansoni hypothetical protein 0.0343 0.1378 0.1378
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0011 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0015 0.0015
Echinococcus multilocularis fmrfamide receptor 0.0011 0.0015 0.0015
Trypanosoma brucei cytochrome P450, putative 0.0029 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Echinococcus granulosus hypothetical protein 0.0011 0.0015 0.0015
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0017 0.0017
Brugia malayi hypothetical protein 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0008 0.0002 0.0002
Plasmodium vivax splicing factor 3B subunit 3, putative 0.0033 0.0103 0.0103
Echinococcus granulosus G protein coupled receptor 139 0.0011 0.0015 0.0015
Schistosoma mansoni neuropeptide receptor 0.0011 0.0015 0.0015
Leishmania major serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0313 0.1254 0.1256
Loa Loa (eye worm) G-protein coupled receptor 0.0011 0.0015 0.0015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0283 0.0283
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0011 0.0015 0.0015
Mycobacterium ulcerans beta-lactamase 0.0043 0.0146 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0185 0.0185
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0017 0.0038 0.0038
Echinococcus granulosus tm gpcr rhodopsin 0.0011 0.0015 0.0015
Echinococcus multilocularis g protein coupled receptor 0.0011 0.0015 0.0015
Schistosoma mansoni amine GPCR 0.0011 0.0015 0.0015
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0057 0.0202 0.0202
Loa Loa (eye worm) steroid hormone receptor 0.0057 0.0202 0.0202
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.003 0.0093 0.0675
Schistosoma mansoni biogenic amine receptor 0.0011 0.0015 0.0015
Echinococcus multilocularis cpg binding protein 0.0036 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0041 0.0041
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0011 0.0015 0.0015
Toxoplasma gondii Hsp90 domain-containing protein 0.0016 0.0032 0.0235
Trypanosoma cruzi cysteine protease, putative 0.001 0.0011 0.0011
Onchocerca volvulus 0.0344 0.1381 1
Echinococcus granulosus cathepsin L cysteine protease 0.001 0.0011 0.0011
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0057 0.0202 0.0202
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0008 0.0002 0.0002
Echinococcus multilocularis g protein coupled receptor 0.0011 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0015 0.0015
Schistosoma mansoni endoplasmin 0.0038 0.0125 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0098 0.0098
Onchocerca volvulus 0.0027 0.0078 0.0567
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0146 0.0146
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0063 0.0063
Schistosoma mansoni cytochrome P450 0.0008 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0098 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0009 0.0009
Echinococcus granulosus allatostatin A receptor 0.0011 0.0015 0.0015
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0011 0.0015 0.0015
Brugia malayi sodium-independent organic anion transporter family protein 0.0033 0.0103 0.0103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0283 0.0283
Brugia malayi Serine/threonine protein phosphatase 2B catalytic subunit 2 0.0313 0.1254 0.1256
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0096 0.0096
Brugia malayi PXA domain containing protein 0.0023 0.0063 0.0063
Loa Loa (eye worm) nuclear hormone receptor 0.0027 0.0078 0.0078
Trichomonas vaginalis heat shock protein, putative 0.0016 0.0032 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0048 0.0048
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0129 0.013
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0053 0.0185 0.0185
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0011 0.0015 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Onchocerca volvulus 0.0011 0.0015 0.0111
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0033 0.0103 0.0103
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0151 0.0589 0.0589
Leishmania major cytochrome p450-like protein 0.0008 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Plasmodium vivax heat shock protein, putative 0.0016 0.0032 0.0032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0078 0.0078
Echinococcus multilocularis cysteine protease 0.002 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0146 0.0146
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0063 0.0063
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0053 0.0185 0.0185
Brugia malayi cathepsin L-like precursor 0.0013 0.0023 0.0023
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0008 0.0002 0.0002
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0051 0.0051
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0008 0.0002 0.0016
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0053 0.0185 0.0185
Loa Loa (eye worm) CXXC zinc finger family protein 0.0034 0.011 0.011
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0061 0.0061
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0053 0.0185 0.0185
Mycobacterium ulcerans bacterioferritin BfrA 0.001 0.0009 0.0009
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0002 0.0002
Mycobacterium tuberculosis Conserved protein 0.0043 0.0146 0.1056
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0008 0.0002 0.0002
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0051 0.0051
Loa Loa (eye worm) G-protein coupled receptor 0.0011 0.0015 0.0015
Leishmania major DNA polymerase eta, putative 0.0017 0.0038 0.0038
Onchocerca volvulus 0.002 0.0051 0.0366
Schistosoma mansoni terminal deoxycytidyl transferase 0.0017 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0057 0.0202 0.0202
Brugia malayi neuropeptide F receptor 0.0011 0.0015 0.0015
Brugia malayi nuclear hormone receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.0063 0.0063
Treponema pallidum bacterioferrin (TpF1) 0.001 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0023 0.0063 0.0063
Trypanosoma cruzi cruzipain precursor, putative 0.0076 0.0283 0.0283
Trypanosoma cruzi Heat shock protein 83, putative 0.0038 0.0125 0.0125
Schistosoma mansoni nuclear receptor 0.0027 0.0078 0.0078
Trichomonas vaginalis fk506-binding protein, putative 0.2437 0.9989 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0057 0.0202 0.0202
Echinococcus granulosus splicing factor 3b subunit 3 0.0033 0.0103 0.0103
Brugia malayi Cathepsin L-like precursor 0.0013 0.0023 0.0023
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0063 0.0063
Echinococcus multilocularis 0.0392 0.158 0.158
Toxoplasma gondii heat shock protein HSP90 0.0038 0.0125 0.0907
Onchocerca volvulus 0.0011 0.0015 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0146 0.0146
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0063 0.0063
Brugia malayi nuclear hormone receptor family member nhr-6 0.0027 0.0078 0.0078
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis dro:myosuppressin receptor 0.0011 0.0015 0.0015
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0041 0.0041
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0025 0.007 0.0506
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0002 0.0002
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.003 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0022 0.006 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.0032
Echinococcus multilocularis heat shock protein 90 0.0038 0.0125 0.0125
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0057 0.0202 0.0202
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Schistosoma mansoni zinc finger protein 0.0027 0.0078 0.0078
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.244 1 1
Echinococcus granulosus expressed protein 0.0448 0.1808 0.1808
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0063 0.0063
Brugia malayi neuropeptide F receptor 0.0011 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0029 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.0063 0.0063
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0011 0.0015 0.0015
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0392 0.158 0.1581
Echinococcus granulosus cathepsin l1 0.002 0.0051 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0085 0.0085
Trypanosoma brucei heat shock protein, putative 0.0038 0.0125 0.0125
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.244 1 1
Echinococcus multilocularis neuropeptides capa receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0022 0.006 0.006
Echinococcus granulosus g protein coupled receptor 0.0011 0.0015 0.0015
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0011 0.0015 0.0015
Trypanosoma cruzi cysteine proteinase, putative 0.001 0.0011 0.0011
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0032 0.0032
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0033 0.0103 0.0103
Onchocerca volvulus 0.0011 0.0015 0.0111
Trichomonas vaginalis heat shock protein, putative 0.003 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0023 0.0063 0.0063
Trypanosoma cruzi MFS transporter, putative 0.0033 0.0103 0.0103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0015 0.0015
Onchocerca volvulus 0.0011 0.0015 0.0111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0283 0.0283
Echinococcus granulosus dnaJ subfamily B 0.049 0.1985 0.1985
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Onchocerca volvulus 0.0033 0.0103 0.0743
Trichomonas vaginalis heat shock protein, putative 0.0038 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0023 0.0063 0.0063
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0063 0.0063
Trichomonas vaginalis heat shock protein, putative 0.003 0.0093 0.0093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0283 0.0283
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0057 0.0202 0.0202
Onchocerca volvulus 0.0011 0.0015 0.0111
Brugia malayi nuclear receptor RXR 0.0027 0.0078 0.0078
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0118 0.0118
Brugia malayi hypothetical protein 0.0011 0.0015 0.0015
Schistosoma mansoni biogenic amine receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.0063 0.0063
Schistosoma mansoni RAR-like nuclear receptor 0.0057 0.0202 0.0202
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0185 0.0185
Trypanosoma brucei heat shock protein, putative 0.0038 0.0125 0.0125
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0038 0.0038
Brugia malayi G protein-coupled receptor F59B2.13 0.0011 0.0015 0.0015
Schistosoma mansoni alpha-1 adrenergic receptor 0.0011 0.0015 0.0015
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Schistosoma mansoni opsin-like receptor 0.0011 0.0015 0.0015
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0023 0.0023
Echinococcus granulosus thyroid hormone receptor alpha 0.0027 0.0078 0.0078
Mycobacterium ulcerans hypothetical protein 0.0392 0.158 0.1581
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0092
Brugia malayi hypothetical protein 0.0011 0.0015 0.0015
Echinococcus granulosus heat shock protein 90 0.003 0.0093 0.0093
Brugia malayi polk-prov protein 0.0036 0.0118 0.0118
Entamoeba histolytica cysteine proteinase 1, putative 0.001 0.0011 0.0011
Schistosoma mansoni follistatin 0.0022 0.006 0.006
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Leishmania major DNA polymerase kappa, putative 0.0025 0.007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0011 0.0015 0.0015
Leishmania major hypothetical protein, conserved 0.0043 0.0146 0.0146
Loa Loa (eye worm) CYP4Cod1 0.0029 0.0087 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0057 0.0202 0.0202
Echinococcus granulosus orexin receptor type 2 0.0011 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0023 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0043 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0092
Brugia malayi nuclear receptor NHR-88 0.0027 0.0078 0.0078
Schistosoma mansoni fkbp-rapamycin associated protein 0.001 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0057 0.0202 0.0202
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0033 0.0103 0.0103
Echinococcus multilocularis g protein coupled receptor 0.0011 0.0015 0.0015
Onchocerca volvulus Cathepsin L homolog 0.002 0.0051 0.0366
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0008 0.0002 0.0016
Trypanosoma cruzi DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0008 0.0002 0.0016
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0011 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Schistosoma mansoni retinoic acid receptor RXR 0.0057 0.0202 0.0202
Echinococcus granulosus alpha 1A adrenergic receptor 0.0011 0.0015 0.0015
Echinococcus granulosus neuropeptide Y receptor 0.0011 0.0015 0.0015
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0063 0.0063
Echinococcus granulosus peptide allatostatin:somatostatin 0.0011 0.0015 0.0015
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.006 0.006
Trypanosoma brucei heat shock protein, putative 0.0038 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0051 0.0051
Trypanosoma cruzi heat shock protein, putative 0.0016 0.0032 0.0032
Toxoplasma gondii FATC domain-containing protein 0.001 0.0009 0.0066
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.0101 0.0101
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0151 0.0589 0.0589
Toxoplasma gondii protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein 0.0313 0.1254 0.9103
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0008 0.0002 0.0002
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0057 0.0202 0.0202
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0051
Brugia malayi ORL1-like opioid receptor 0.0011 0.0015 0.0015
Echinococcus granulosus ecdysone induced protein 78C 0.0057 0.0202 0.0202
Echinococcus multilocularis neuropeptide Y receptor 0.0011 0.0015 0.0015
Schistosoma mansoni cpg binding protein 0.0034 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0032 0.0101 0.0101
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0071 0.0071
Onchocerca volvulus Putative organic anion transporter 0.0033 0.0103 0.0743
Brugia malayi orphan nuclear receptor NR2E1 0.0027 0.0078 0.0078
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.003 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Brugia malayi Tachykinin-like peptides receptor 99D 0.0011 0.0015 0.0015
Brugia malayi hypothetical protein 0.0011 0.0015 0.0015
Onchocerca volvulus 0.002 0.0051 0.0366
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0283 0.0283
Echinococcus multilocularis allatostatin A receptor 0.0011 0.0015 0.0015
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.001 0.0009 0.0009
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0146 0.0146
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0008 0.0002 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0141 0.0141
Brugia malayi Cytochrome P450 family protein 0.0008 0.0002 0.0002
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0313 0.1254 0.1254
Trichomonas vaginalis fk506-binding protein, putative 0.0343 0.1378 0.138
Loa Loa (eye worm) hypothetical protein 0.0057 0.0202 0.0202
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0039 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Onchocerca volvulus 0.0043 0.0146 0.1054
Onchocerca volvulus 0.0011 0.0015 0.0111
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.2437 0.9989 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0011 0.0015 0.0015
Schistosoma mansoni ap endonuclease 0.0023 0.0061 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0011 0.0011
Schistosoma mansoni amine GPCR 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0051
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0011 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0015 0.0015
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.006 0.006
Schistosoma mansoni adenoreceptor 0.0011 0.0015 0.0015
Schistosoma mansoni nuclear hormone receptor 0.0057 0.0202 0.0202
Brugia malayi nuclear receptor NHR-88 0.0057 0.0202 0.0202
Schistosoma mansoni coup transcription factor 0.0057 0.0202 0.0202
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0313 0.1254 0.1254
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0008 0.0002 0.0002
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0343 0.1378 1
Trypanosoma brucei Heat shock protein 83, putative 0.0038 0.0125 0.0125
Schistosoma mansoni microtubule-associated protein tau 0.0827 0.337 0.337
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0051 0.0051
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0011 0.0015 0.0111
Loa Loa (eye worm) heat shock protein 75 0.0016 0.0032 0.0032
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0008 0.0002 0.0002
Brugia malayi Dopamine receptor protein 1 0.0011 0.0015 0.0015
Onchocerca volvulus 0.0022 0.006 0.0434
Loa Loa (eye worm) hypothetical protein 0.0033 0.0103 0.0103
Onchocerca volvulus Putative organic anion transporter 0.0033 0.0103 0.0743
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Echinococcus multilocularis expressed protein 0.001 0.0009 0.0009
Echinococcus multilocularis serotonin receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) heat shock protein 90 0.0038 0.0125 0.0125
Plasmodium falciparum cysteine proteinase falcipain 1 0.001 0.0011 0.0011
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0343 0.1378 0.138
Schistosoma mansoni heat shock protein 0.0038 0.0125 0.0125
Trypanosoma cruzi cysteine proteinase, putative 0.001 0.0011 0.0011
Schistosoma mansoni amine GPCR 0.0011 0.0015 0.0015
Echinococcus multilocularis 0.0008 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0023 0.0063 0.0063
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0392 0.158 0.158
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Onchocerca volvulus 0.002 0.0051 0.0366
Schistosoma mansoni opsin-like receptor 0.0011 0.0015 0.0015
Echinococcus granulosus cytochrome P450 2K1 0.0008 0.0002 0.0002
Brugia malayi Cytochrome P450 family protein 0.0029 0.0087 0.0087
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0063 0.0063
Toxoplasma gondii protease inhibitor PI2 0.0022 0.006 0.0435
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0313 0.1254 0.1254
Entamoeba histolytica cysteine proteinase 2 0.001 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0308 0.1236 0.1238
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0061 0.0061
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0008 0.0002 0.0016
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.2437 0.9989 1
Echinococcus multilocularis dna polymerase eta 0.0017 0.0038 0.0038
Trichomonas vaginalis heat shock protein, putative 0.0023 0.0064 0.0064
Trypanosoma cruzi cysteine peptidase, putative 0.001 0.0011 0.0011
Schistosoma mansoni DNA polymerase eta 0.0017 0.0038 0.0038
Echinococcus multilocularis geminin 0.0402 0.1621 0.1621
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0343 0.1378 0.138
Trypanosoma brucei heat shock protein, putative 0.0038 0.0125 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0057 0.0202 0.0202
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.001 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0343 0.1378 0.138
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.003 0.0093 0.0675
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0011 0.0014 0.01
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Schistosoma mansoni organic anion transporter 0.0033 0.0103 0.0103
Brugia malayi nuclear hormone receptor family member odr-7 0.0027 0.0078 0.0078
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0118 0.0118
Onchocerca volvulus 0.0011 0.0015 0.0111
Schistosoma mansoni intermediate filament proteins 0.0032 0.0101 0.0101
Schistosoma mansoni heat shock protein 0.0038 0.0125 0.0125
Echinococcus multilocularis neuropeptide receptor 0.0011 0.0015 0.0015
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Onchocerca volvulus 0.002 0.0051 0.0366
Echinococcus multilocularis g-protein coupled receptor 0.0011 0.0015 0.0015
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0063 0.0063
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.2437 0.9989 1
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0008 0.0002 0.0002
Echinococcus granulosus dna polymerase eta 0.0017 0.0038 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0041 0.0041
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0025 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0022 0.006 0.006
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0036 0.0118 0.0118
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0048 0.0048
Schistosoma mansoni ferritin 0.001 0.0009 0.0009
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0041 0.0041
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0118 0.0118
Loa Loa (eye worm) nuclear receptor NHR-67 0.0027 0.0078 0.0078
Echinococcus granulosus cathepsin l1 0.0013 0.0023 0.0023
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0051 0.0051
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0016 0.0032 0.0032
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0343 0.1378 0.138
Schistosoma mansoni apoferritin-2 0.001 0.0009 0.0009
Brugia malayi GnHR receptor homolog 0.0011 0.0015 0.0015
Schistosoma mansoni lamin 0.0032 0.0101 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0053 0.0185 0.0185
Echinococcus granulosus heat shock protein 90 0.0038 0.0125 0.0125
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0313 0.1254 0.1254
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Leishmania major cathepsin L-like protease 0.0076 0.0283 0.0283
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0057 0.0202 0.0202
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0008 0.0002 0.0002
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0098 0.0098
Trypanosoma cruzi heat shock protein 90, putative 0.0038 0.0125 0.0125
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.006 0.0435
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0011 0.0015 0.0015
Mycobacterium ulcerans heat shock protein 90 0.003 0.0093 0.0093
Trichomonas vaginalis fk506 binding protein, putative 0.0343 0.1378 0.138
Echinococcus granulosus microtubule associated protein 2 0.0827 0.337 0.337
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0009 0.0009
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Toxoplasma gondii heat shock protein 90, putative 0.0038 0.0125 0.0907
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0011 0.0011
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0146 0.1056
Loa Loa (eye worm) endoplasmin 0.0038 0.0125 0.0125
Loa Loa (eye worm) agrin synaptic family protein 0.0022 0.006 0.006
Brugia malayi PXA domain containing protein 0.0023 0.0063 0.0063
Treponema pallidum heat shock protein 90 0.003 0.0093 0.0093
Trypanosoma cruzi target of rapamycin kinase 3 0.0042 0.0141 0.0141
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Schistosoma mansoni ferritin 0.001 0.0009 0.0009
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0051 0.0051
Mycobacterium leprae Conserved hypothetical protein 0.0008 0.0002 0.0016
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0009 0.0009
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0011 0.0015 0.0015
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0057 0.0202 0.0202
Brugia malayi follicle stimulating hormone receptor 0.0011 0.0015 0.0015
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0027 0.0078 0.0567
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Trypanosoma cruzi heat shock protein 85, putative 0.0038 0.0125 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0015 0.0015
Trypanosoma cruzi DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0343 0.1378 0.138
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.006 0.006
Plasmodium vivax vivapain-2 0.002 0.0051 0.0051
Loa Loa (eye worm) RGS-3 protein 0.0023 0.0063 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0129 0.013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0343 0.1378 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Brugia malayi hypothetical protein 0.0011 0.0015 0.0015
Toxoplasma gondii exonuclease III APE 0.0023 0.0061 0.0441
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0.0015 0.0015
Trypanosoma cruzi heat shock protein 90, putative 0.0023 0.0061 0.0061
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0011 0.0015 0.0015
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.2437 0.9989 0.9997
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0011 0.0015 0.0015
Brugia malayi G protein-coupled receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.0063 0.0063
Echinococcus granulosus neuropeptide s receptor 0.0011 0.0015 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0008 0.0002 0.0002
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0027 0.0078 0.0078
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.2437 0.9989 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0041 0.0041
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0033 0.0103 0.0103
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0011 0.0015 0.0015
Schistosoma mansoni apoferritin-2 0.001 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0118 0.0118
Onchocerca volvulus 0.0285 0.1139 0.8249
Brugia malayi hypothetical protein 0.0023 0.0063 0.0063
Trichomonas vaginalis ferritin, putative 0.001 0.0009 0.0009
Plasmodium vivax vivapain-1 0.001 0.0011 0.0011
Schistosoma mansoni neuropeptide f receptor 76f 0.0011 0.0015 0.0015
Echinococcus multilocularis serotonin receptor 0.0011 0.0015 0.0015
Brugia malayi sodium-independent organic anion transporter family protein 0.0033 0.0103 0.0103
Trypanosoma brucei heat shock protein, putative 0.0038 0.0125 0.0125
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0008 0.0002 0.0002
Onchocerca volvulus 0.0011 0.0015 0.0111
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0343 0.1378 0.138
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0017 0.0017
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0057 0.0202 0.0202
Giardia lamblia Hypothetical protein 0.0343 0.1378 0.138
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0008 0.0002 0.0016
Echinococcus multilocularis serine protein kinase ATM 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.011 0.011
Onchocerca volvulus 0.0057 0.0202 0.1462
Loa Loa (eye worm) hypothetical protein 0.0043 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0343 0.1378 0.138
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.003 0.0092 0.0092
Brugia malayi hypothetical protein 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0343 0.1378 0.138
Schistosoma mansoni neuropeptide receptor 0.0011 0.0015 0.0015
Brugia malayi RE15519p 0.0011 0.0015 0.0015
Echinococcus granulosus neuropeptide FF receptor 2 0.0011 0.0015 0.0015
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0011 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0343 0.1378 0.138
Brugia malayi CXXC zinc finger family protein 0.0034 0.011 0.011
Schistosoma mansoni neuropeptide receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0033 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0057 0.0202 0.0202
Leishmania major heat shock protein, putative 0.0016 0.0032 0.0032
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0.0015 0.0015
Plasmodium falciparum serine/threonine protein phosphatase 2B catalytic subunit A 0.0313 0.1254 0.1256
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0011 0.0011
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.003 0.0093 0.0675
Brugia malayi photoreceptor-specific nuclear receptor 0.0057 0.0202 0.0202
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.001 0.0009 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0283 0.0283
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Onchocerca volvulus 0.0011 0.0015 0.0111
Trichomonas vaginalis spliceosomal protein sap, putative 0.0033 0.0103 0.0103
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.2437 0.9989 1
Onchocerca volvulus 0.002 0.0051 0.0366
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0011 0.0011
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0343 0.1378 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0061 0.0218 0.0218
Echinococcus granulosus 7tm_1 domain containing protein 0.0011 0.0015 0.0015
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.001 0.0009 0.0065
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0343 0.1378 0.1378
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0057 0.0202 0.0202
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Echinococcus granulosus geminin 0.0402 0.1621 0.1621
Onchocerca volvulus 0.002 0.0051 0.0366
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0057 0.0202 0.0202
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0027 0.0078 0.0078
Schistosoma mansoni amine GPCR 0.0011 0.0015 0.0015
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0041 0.0041
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0011 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0063 0.0063
Brugia malayi hypothetical protein 0.0011 0.0015 0.0015
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.2437 0.9989 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0015 0.0015
Trypanosoma brucei heat shock protein 90, putative 0.0038 0.0125 0.0125
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.001 0.0011 0.0011
Onchocerca volvulus 0.0027 0.0078 0.0567
Schistosoma mansoni protein phosphatase-2b 0.0313 0.1254 0.1254
Onchocerca volvulus 0.0011 0.0015 0.0111
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0057 0.0202 0.0202
Entamoeba histolytica cysteine protease, putative 0.002 0.0051 0.0051
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0313 0.1254 0.1254
Echinococcus multilocularis heat shock protein 0.0038 0.0125 0.0125
Echinococcus granulosus dna polymerase kappa 0.0048 0.0166 0.0166
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0057 0.0202 0.1462
Brugia malayi Dopamine receptor protein 2 0.0011 0.0015 0.0015
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0146 0.1056
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0008 0.0002 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0129 0.013
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0313 0.1254 0.1254
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0146 0.0146
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0057 0.0202 0.0202
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0185 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0041 0.0041
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0063 0.0063
Schistosoma mansoni immunophilin 0.2097 0.859 0.859
Mycobacterium ulcerans bacterioferritin BfrB 0.001 0.0009 0.0009
Echinococcus multilocularis lamin dm0 0.0032 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0033 0.0103 0.0103
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0041 0.0041
Loa Loa (eye worm) cysteine protease 0.002 0.0051 0.0051
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0008 0.0002 0.0016
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0063 0.0063
Onchocerca volvulus 0.0033 0.0103 0.0743
Loa Loa (eye worm) hypothetical protein 0.0022 0.006 0.006
Plasmodium vivax unspecified product 0.001 0.0011 0.0011
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0061 0.0061
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0051
Echinococcus multilocularis cysteine protease 0.002 0.0051 0.0051
Brugia malayi Papain family cysteine protease containing protein 0.001 0.0011 0.0011
Echinococcus multilocularis cathepsin L 0.001 0.0011 0.0011
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.0063 0.0063
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.2437 0.9989 1
Echinococcus granulosus endoplasmin 0.003 0.0093 0.0093
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0008 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0129 0.013
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.244 1 1
Loa Loa (eye worm) fibroinase 0.002 0.0051 0.0051
Brugia malayi hypothetical protein 0.003 0.0092 0.0092
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0343 0.1378 0.138
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0063 0.0063
Onchocerca volvulus 0.0037 0.0118 0.0857
Echinococcus granulosus tachykinin peptides receptor 99D 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0037 0.0118 0.0118
Brugia malayi Nuclear hormone receptor E75 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Mycobacterium leprae putative cytochrome p450 0.0008 0.0002 0.0016
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0017 0.0038 0.0038
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0343 0.1378 0.1378
Mycobacterium tuberculosis Conserved protein 0.0043 0.0146 0.1056
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0343 0.1378 0.138
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0011 0.0015 0.0015
Schistosoma mansoni neuropeptide F-like receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0015 0.003 0.003
Onchocerca volvulus 0.0013 0.0023 0.0169
Schistosoma mansoni nuclear receptor 0.0027 0.0078 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0283 0.0283
Onchocerca volvulus Cathepsin F homolog 0.002 0.0051 0.0366
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0051 0.0051
Echinococcus multilocularis heat shock protein 90 0.003 0.0093 0.0093
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0274 0.0274
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0129 0.013
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0343 0.1378 1
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0011 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0146 0.1056
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0053 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Onchocerca volvulus Neuropeptide F receptor homolog 0.0011 0.0015 0.0111
Trypanosoma brucei DNA polymerase IV, putative 0.0048 0.0166 0.0166
Plasmodium vivax endoplasmin, putative 0.0038 0.0125 0.0125
Echinococcus granulosus somatostatin receptor 0.0011 0.0015 0.0015
Onchocerca volvulus 0.0343 0.1378 0.998
Echinococcus granulosus neuropeptide receptor 0.0011 0.0015 0.0015
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0346 0.1389 0.1389
Toxoplasma gondii transporter, major facilitator family protein 0.0033 0.0103 0.0745
Schistosoma mansoni hypothetical protein 0.0011 0.0015 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0008 0.0002 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0041 0.0041
Onchocerca volvulus 0.0032 0.0101 0.0732
Brugia malayi nuclear receptor NHR-67 0.0027 0.0078 0.0078
Trypanosoma brucei unspecified product 0.0012 0.0016 0.0016
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0063 0.0063
Brugia malayi Melatonin receptor type 1A 0.0011 0.0015 0.0015
Brugia malayi prostaglandin transporter 0.0033 0.0103 0.0103
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0008 0.0002 0.0016
Brugia malayi heat shock protein 90 0.0038 0.0125 0.0125
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0061 0.0441
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0134 0.0135
Leishmania major cytochrome p450-like protein 0.0008 0.0002 0.0002
Schistosoma mansoni ap endonuclease 0.0023 0.0061 0.0061
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0051 0.0051
Echinococcus granulosus heat shock protein 0.0038 0.0125 0.0125
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0008 0.0002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Echinococcus multilocularis orexin receptor type 2 0.0011 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0023 0.0023
Echinococcus granulosus cysteine protease 0.001 0.0011 0.0011
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0063 0.0063
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.0078 0.0078
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.001 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0283 0.0283
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.001 0.0009 0.0009
Echinococcus granulosus cathepsin L 0.001 0.0011 0.0011
Loa Loa (eye worm) neuropeptide F receptor 0.0011 0.0015 0.0015
Echinococcus granulosus neuropeptide Y receptor 0.0011 0.0015 0.0015
Echinococcus multilocularis sex peptide receptor 0.0011 0.0015 0.0015
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0008 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0008 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0023 0.0023
Trichomonas vaginalis endoplasmin, putative 0.0023 0.0064 0.0064
Toxoplasma gondii target of rapamycin (TOR), putative 0.0039 0.0129 0.0939
Echinococcus multilocularis microtubule associated protein 2 0.0827 0.337 0.337
Echinococcus multilocularis neuropeptide s receptor 0.0011 0.0015 0.0015
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0061 0.0061
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0011 0.0015 0.0015
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.2437 0.9989 1
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Onchocerca volvulus Putative organic anion transporter 0.0033 0.0103 0.0743
Trichomonas vaginalis esterase, putative 0.0043 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0057 0.0202 0.0202
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0146 0.0146
Trypanosoma cruzi DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.0255 0.0256
Trichomonas vaginalis immunophilin, putative 0.2437 0.9989 1
Giardia lamblia Grp94/Hsp90 0.003 0.0093 0.0093
Giardia lamblia Heat shock protein HSP 90-alpha 0.0038 0.0125 0.0125
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0063 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0283 0.0283
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0063 0.0063
Trypanosoma brucei unspecified product 0.0012 0.0016 0.0016
Trypanosoma cruzi heat shock protein 85, putative 0.0038 0.0125 0.0125
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0053 0.0185 0.0185
Entamoeba histolytica heat shock protein 90, putative 0.0038 0.0125 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0141 0.0141
Echinococcus granulosus fmrfamide receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0015 0.003 0.003
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0022 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Trypanosoma brucei protein phosphatase 2B, putative 0.0313 0.1254 0.1256
Onchocerca volvulus 0.0043 0.0146 0.1054
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0011 0.0015 0.0015
Trypanosoma brucei heat shock protein 84, putative 0.0016 0.0032 0.0032
Trichomonas vaginalis set domain proteins, putative 0.0285 0.1139 0.114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0041 0.0041
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0313 0.1254 0.1254
Brugia malayi AKH receptor 0.0011 0.0015 0.0015
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0392 0.158 0.1581
Brugia malayi Cytochrome P450 family protein 0.0008 0.0002 0.0002
Plasmodium falciparum heat shock protein 90, putative 0.0016 0.0032 0.0032
Brugia malayi Nuclear hormone receptor E75 0.0027 0.0078 0.0078
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.0078 0.0078
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0027 0.0078 0.0078
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Brugia malayi ecdysteroid receptor 0.0057 0.0202 0.0202
Echinococcus multilocularis agrin 0.0022 0.006 0.006
Echinococcus granulosus follistatin 0.0022 0.006 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0141 0.0141
Echinococcus multilocularis G-protein coupled receptor, putative 0.0011 0.0015 0.0015
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.2097 0.859 0.859
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0061 0.0441
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.0038 0.0275
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0008 0.0002 0.0016
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0057 0.0202 0.0202
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0015 0.0015
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.0063 0.0063
Echinococcus granulosus FTZ F1 alpha 0.0057 0.0202 0.0202
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0146 0.1056
Echinococcus granulosus intermediate filament protein 0.0032 0.0101 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0057 0.0202 0.0202
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0027 0.0078 0.0078
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0392 0.158 0.1581
Trypanosoma cruzi heat shock protein 85, putative 0.0038 0.0125 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0313 0.1254 0.1256
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0008 0.0002 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0043 0.0146 0.0146
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.006 0.0435
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0051 0.0051
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0011 0.0011
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0027 0.0078 0.0078
Entamoeba histolytica hypothetical protein 0.001 0.0009 0.0009
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0027 0.0078 0.0078
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0146 0.1056
Brugia malayi hypothetical protein 0.0011 0.0015 0.0015
Echinococcus multilocularis neuropeptides capa receptor 0.0011 0.0015 0.0015
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Schistosoma mansoni thyroid hormone receptor 0.0208 0.0822 0.0822
Onchocerca volvulus 0.0011 0.0015 0.0111
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.001 0.0009 0.0009
Brugia malayi G-protein coupled receptor 0.0011 0.0015 0.0015
Echinococcus granulosus g-protein coupled receptor 0.0011 0.0015 0.0015
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0343 0.1378 0.138
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0092
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0057 0.0202 0.0202
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0057 0.0202 0.0202
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0063 0.0063
Onchocerca volvulus 0.0011 0.0015 0.0111
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0008 0.0002 0.0002
Echinococcus granulosus lamin 0.0032 0.0101 0.0101
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.006 0.006
Schistosoma mansoni biogenic amine receptor 0.0011 0.0015 0.0015
Echinococcus multilocularis expressed protein 0.0022 0.006 0.006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0146 0.0146
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0118 0.0118
Echinococcus multilocularis fk506 binding protein 0.2437 0.9989 0.9989
Plasmodium vivax vivapain-3 0.001 0.0011 0.0011
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0061 0.0061
Plasmodium falciparum endoplasmin, putative 0.0023 0.0064 0.0064
Echinococcus multilocularis endoplasmin 0.003 0.0093 0.0093
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0092 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0051 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0129 0.013
Leishmania major serine/threonine protein phosphatase, putative 0.0313 0.1254 0.1256
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0972 0.3966 0.3966
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Trypanosoma brucei heat shock protein, putative 0.0038 0.0125 0.0125
Schistosoma mansoni ferritin light chain 0.001 0.0009 0.0009
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0051 0.0051
Loa Loa (eye worm) intermediate filament protein 0.0032 0.0101 0.0101
Brugia malayi steroid hormone receptor 0.0057 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0009
Trypanosoma cruzi DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0017 0.0038 0.0038
Brugia malayi nuclear hormone receptor 0.0057 0.0202 0.0202
Echinococcus multilocularis musashi 0.0032 0.0101 0.0101
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0011 0.0015 0.0015
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0051
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0061 0.0061
Leishmania major cytochrome p450-like protein 0.0029 0.0087 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0057 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0041 0.0041
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0061 0.0061
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0061 0.0061
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.0063 0.0063
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0017 0.0017
Leishmania major cathepsin L-like protease 0.0076 0.0283 0.0283
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Trypanosoma brucei heat shock protein 90, putative 0.0038 0.0125 0.0125
Brugia malayi Pre-SET motif family protein 0.0037 0.0118 0.0118
Brugia malayi ecdysone receptor 0.0027 0.0078 0.0078
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.2437 0.9989 1
Trypanosoma cruzi heat shock protein 85, putative 0.003 0.0093 0.0093
Brugia malayi hypothetical protein 0.003 0.0092 0.0092
Echinococcus multilocularis lamin 0.0032 0.0101 0.0101
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.2437 0.9989 1
Brugia malayi secreted modular calcium-binding protein 1 0.0022 0.006 0.006
Echinococcus multilocularis somatostatin receptor 0.0011 0.0015 0.0015
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0011 0.0015 0.0015
Brugia malayi sodium-independent organic anion transporter family protein 0.0033 0.0103 0.0103
Trypanosoma brucei hypothetical protein, conserved 0.0343 0.1378 0.138
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0011 0.0015 0.0015
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0051 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Echinococcus granulosus agrin 0.0022 0.006 0.006
Echinococcus multilocularis nuclear receptor nhr 48 0.0027 0.0078 0.0078
Brugia malayi hypothetical protein 0.0011 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0023 0.0023
Brugia malayi Endoplasmin precursor 0.0038 0.0125 0.0125
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0051
Echinococcus granulosus FK506 binding protein 2 0.0392 0.158 0.158
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0063 0.0063
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0085 0.0085
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0343 0.1378 0.138
Brugia malayi Cathepsin L-like precursor 0.0013 0.0023 0.0023
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.006 0.0435
Brugia malayi Cytochrome P450 family protein 0.0029 0.0087 0.0087
Mycobacterium ulcerans lipase LipD 0.0043 0.0146 0.0146
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0033 0.0103 0.0103
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0017 0.0038 0.0038
Toxoplasma gondii cathepsin CPL 0.002 0.0051 0.0367
Onchocerca volvulus 0.0011 0.0015 0.0111
Onchocerca volvulus 0.0033 0.0103 0.0743
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0146 0.1056
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0092
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) neuropeptide F receptor 0.0011 0.0015 0.0015
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.2437 0.9989 0.9989
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0051 0.0051
Onchocerca volvulus 0.0033 0.0103 0.0743
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0016 0.0032 0.0032
Brugia malayi nuclear receptor RXR 0.003 0.0092 0.0092
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0146 0.0146
Onchocerca volvulus Cathepsin L homolog 0.002 0.0051 0.0366
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0008 0.0002 0.0002
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0063 0.0063
Echinococcus granulosus 7TM GPCR rhodopsin 0.0011 0.0015 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0063 0.0063
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.2437 0.9989 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0118 0.0118
Schistosoma mansoni hypothetical protein 0.0151 0.0589 0.0589
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.0078 0.0078
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0051
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0011 0.0015 0.0015
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0058 0.0058
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Mycobacterium ulcerans DNA polymerase IV 0.0048 0.0166 0.0166
Brugia malayi cytochrome P450 0.0008 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Entamoeba histolytica CPSF A subunit region protein, putative 0.0033 0.0103 0.0103
Brugia malayi hypothetical protein 0.0023 0.0063 0.0063
Onchocerca volvulus 0.0033 0.0103 0.0743
Schistosoma mansoni myosin xvIII 0.0011 0.0015 0.0015
Schistosoma mansoni biogenic amine (5HT) receptor 0.0011 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0051
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0011 0.0015 0.0015
Onchocerca volvulus Protein ultraspiracle homolog 0.0057 0.0202 0.1462
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0118 0.0118
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.007 0.007
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0042 0.0141 0.0141
Giardia lamblia DINP protein human, muc B family 0.0025 0.007 0.007
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0057 0.0202 0.0202
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0118 0.0118
Leishmania major cysteine peptidase A (CPA) 0.002 0.0051 0.0051
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0011 0.0015 0.0015
Brugia malayi Serotonin receptor 0.0011 0.0015 0.0015
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.001 0.0009 0.0065
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0053 0.0185 0.0185
Brugia malayi hypothetical protein 0.0033 0.0103 0.0103
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0051
Echinococcus multilocularis thyroid hormone receptor alpha 0.0208 0.0822 0.0822
Brugia malayi Steroid receptor seven-up type 2 0.0057 0.0202 0.0202
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0008 0.0002 0.0002
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0343 0.1378 0.138
Trypanosoma brucei heat shock protein, putative 0.0038 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0033 0.0103 0.0103
Brugia malayi intermediate filament protein 0.0032 0.0101 0.0101
Echinococcus multilocularis neuropeptide receptor 0.0011 0.0015 0.0015
Brugia malayi Serotonin receptor 0.0011 0.0015 0.0015
Schistosoma mansoni thyroid hormone receptor 0.0208 0.0822 0.0822
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0063 0.0063
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0008 0.0002 0.0016
Echinococcus granulosus biogenic amine 5HT receptor 0.0011 0.0015 0.0015
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.001 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0051
Schistosoma mansoni growth hormone secretagogue receptor 0.0011 0.0015 0.0015
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.2437 0.9989 1
Echinococcus multilocularis ferritin 0.001 0.0009 0.0009
Brugia malayi beta-lactamase family protein 0.0043 0.0146 0.0146
Brugia malayi beta-lactamase 0.0043 0.0146 0.0146
Schistosoma mansoni protein phosphatase-2b 0.0313 0.1254 0.1254
Entamoeba histolytica protein kinase rad3, putative 0.001 0.0009 0.0009
Giardia lamblia GTOR 0.0053 0.0185 0.0185
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.2097 0.859 0.859
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0276 0.1102 0.7998
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0057 0.0202 0.0202
Toxoplasma gondii ABC1 family protein 0.0043 0.0146 0.1056
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0146 0.0146
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0057 0.0202 0.0202
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0008 0.0002 0.0016
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0063 0.0063
Leishmania major fk506-binding protein 1-like protein 0.2437 0.9989 1
Schistosoma mansoni nuclear receptor nhr-48 0.0027 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0114 0.0114
Brugia malayi Dopamine receptor 0.0011 0.0015 0.0015
Onchocerca volvulus 0.002 0.0051 0.0366
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0051
Entamoeba histolytica deoxycytidyl transferase, putative 0.0017 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0057 0.0202 0.0202
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0008 0.0002 0.0016
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0343 0.1378 0.138
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.003 0.0092 0.0092
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0033 0.0103 0.0103
Echinococcus multilocularis neuropeptide FF receptor 2 0.0011 0.0015 0.0015
Brugia malayi Pre-SET motif family protein 0.025 0.0997 0.0998
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0343 0.1378 0.138
Plasmodium vivax vivapain-2 0.002 0.0051 0.0051
Brugia malayi beta-lactamase family protein 0.0043 0.0146 0.0146
Schistosoma mansoni organic anion transporter 0.0033 0.0103 0.0103
Brugia malayi hypothetical protein 0.0011 0.0015 0.0015
Schistosoma mansoni opsin-like receptor 0.0011 0.0015 0.0015
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0057 0.0202 0.0202
Brugia malayi putative neuropeptide receptor 0.0011 0.0015 0.0015
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0027 0.0078 0.0567
Loa Loa (eye worm) hypothetical protein 0.0057 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0313 0.1254 0.1256
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.0063 0.0063
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0008 0.0002 0.0002
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0343 0.1378 1
Echinococcus multilocularis fmrfamide receptor 0.0011 0.0015 0.0015
Schistosoma mansoni endoplasmin 0.0038 0.0125 0.0125
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus granulosus expressed protein 0.001 0.0009 0.0009
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0039 0.0039
Schistosoma mansoni immunophilin 0.244 1 1
Toxoplasma gondii splicing factor 3b, subunit 3, putative 0.0033 0.0103 0.0744
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0051 0.0051
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0061 0.0061
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.001 0.0009 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0085 0.0085
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0008 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0043 0.0146 0.0146
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0343 0.1378 1
Echinococcus granulosus sex peptide receptor 0.0011 0.0015 0.0015
Schistosoma mansoni ferritin 0.001 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0057 0.0202 0.0202
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0041 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0085 0.0085
Echinococcus granulosus neuropeptide receptor 0.0011 0.0015 0.0015
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0063 0.0063
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0313 0.1254 0.1254
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0146 0.0146
Schistosoma mansoni cpg binding protein 0.0036 0.0118 0.0118
Echinococcus multilocularis G protein coupled receptor 139 0.0011 0.0015 0.0015
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0053 0.0185 0.0185
Echinococcus granulosus biogenic amine 5HT receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0087 0.0087
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0051
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0027 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0051
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni biogenic amine (5HT) receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0057 0.0202 0.0202
Plasmodium falciparum heat shock protein 90, putative 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0023 0.0063 0.0063
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0051 0.0051
Schistosoma mansoni hypothetical protein 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0043 0.0146 0.0146
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0087 0.0087
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0343 0.1378 0.1379
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Giardia lamblia Heat shock protein HSP 90-alpha 0.003 0.0093 0.0093
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.001 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Schistosoma mansoni histamine h1 receptor 0.0011 0.0015 0.0015
Plasmodium falciparum heat shock protein 90 0.0038 0.0125 0.0125
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0313 0.1254 0.1254
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0023
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0078 0.0078
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0008 0.0002 0.0002
Onchocerca volvulus 0.0032 0.0101 0.0732
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0011 0.0015 0.0015
Loa Loa (eye worm) ctsf protein 0.002 0.0051 0.0051
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.049 0.1985 0.1985
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0053 0.0185 0.0185
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Mycobacterium ulcerans DNA polymerase IV 0.0048 0.0166 0.0166
Echinococcus granulosus nuclear receptor nhr 48 0.0027 0.0078 0.0078
Schistosoma mansoni agrin 0.0022 0.006 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0166 0.0166
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0061 0.0061
Echinococcus granulosus cpg binding protein 0.0036 0.0118 0.0118
Plasmodium vivax heat shock protein 90, putative 0.0016 0.0032 0.0032
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0063 0.0063
Toxoplasma gondii cytochrome p450 superfamily protein 0.0008 0.0002 0.0016
Mycobacterium ulcerans hypothetical protein 0.0043 0.0146 0.0146
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0051 0.0051
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Trypanosoma brucei DNA polymerase eta, putative 0.0017 0.0038 0.0038
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0053 0.0185 0.0185
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0013 0.0022 0.0157
Trypanosoma cruzi major cysteine proteinase, putative 0.006 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Brugia malayi sulfakinin receptor protein 0.0011 0.0015 0.0015
Trypanosoma cruzi serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0313 0.1254 0.1256
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Brugia malayi splicing factor 3B subunit 3 0.0033 0.0103 0.0103
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0038 0.0038
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.003 0.0092 0.0092
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.0063 0.0063
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0051
Echinococcus granulosus g protein coupled receptor 0.0011 0.0015 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0057 0.0202 0.0202
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0008 0.0002 0.0002
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0063 0.0063
Echinococcus multilocularis dnaJ subfamily B 0.049 0.1985 0.1985
Schistosoma mansoni cpg binding protein 0.0036 0.0118 0.0118
Leishmania major cathepsin L-like protease 0.0076 0.0283 0.0283
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0008 0.0002 0.0002
Echinococcus multilocularis splicing factor 3b subunit 3 0.0033 0.0103 0.0103
Schistosoma mansoni hypothetical protein 0.0011 0.0015 0.0015
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0051
Echinococcus granulosus dro:myosuppressin receptor 0.0011 0.0015 0.0015
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0103 0.0103
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0008 0.0002 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0057 0.0202 0.0202
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.2437 0.9989 0.9989
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.0078 0.0078
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0048 0.0166 0.0166
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0087 0.0087
Echinococcus granulosus tm gpcr rhodopsin 0.0011 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0141 0.0141
Onchocerca volvulus 0.0011 0.0015 0.0111
Echinococcus multilocularis neuropeptide Y receptor 0.0011 0.0015 0.0015
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Plasmodium vivax heat shock protein 86, putative 0.0038 0.0125 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0129 0.013
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0053 0.0185 0.0185
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0061 0.0061
Mycobacterium tuberculosis Conserved protein 0.0043 0.0146 0.1056
Trichomonas vaginalis fk506-binding protein, putative 0.0343 0.1378 0.138
Echinococcus multilocularis ecdysone induced protein 78C 0.0057 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.002 0.0051 0.0051
Onchocerca volvulus 0.0034 0.011 0.0794
Echinococcus multilocularis expressed protein 0.0448 0.1808 0.1808
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0041 0.0041
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0343 0.1378 0.138
Echinococcus multilocularis dna polymerase kappa 0.0048 0.0166 0.0166
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Brugia malayi putative neuropeptide receptor NPR1 0.0011 0.0015 0.0015
Schistosoma mansoni heat shock protein 0.0016 0.0032 0.0032
Trichomonas vaginalis DNA polymerase eta, putative 0.0048 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0343 0.1378 0.138
Entamoeba histolytica cysteine protease, putative 0.001 0.0011 0.0011
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0283 0.0283
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0011 0.0015 0.0015
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0063 0.0063
Onchocerca volvulus 0.0011 0.0015 0.0111
Echinococcus granulosus g protein coupled receptor 0.0011 0.0015 0.0015
Trichomonas vaginalis heat shock protein, putative 0.003 0.0093 0.0093
Trypanosoma brucei unspecified product 0.004 0.0134 0.0135
Mycobacterium leprae Probable lipase LipE 0.0043 0.0146 0.1056
Echinococcus granulosus serine protein kinase ATM 0.001 0.0009 0.0009
Schistosoma mansoni fk506 binding protein 0.0343 0.1378 0.1378
Entamoeba histolytica heat shock protein 90, putative 0.0038 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0023 0.0063 0.0063
Echinococcus granulosus ferritin 0.001 0.0009 0.0009
Loa Loa (eye worm) TYRA-2 protein 0.0011 0.0015 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0015 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0146 0.0146
Brugia malayi Papain family cysteine protease containing protein 0.001 0.0011 0.0011
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0063 0.0063
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0063 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0283 0.0283
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.2437 0.9989 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Schistosoma mansoni lamin 0.0032 0.0101 0.0101
Trypanosoma brucei heat shock protein, putative 0.0038 0.0125 0.0125
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0146 0.0146
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0392 0.158 0.1581
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0011 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0057 0.0202 0.0202
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0011 0.0011
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0008 0.0002 0.0016
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0063 0.0063
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0146 0.1056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0085 0.0085
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0057 0.0202 0.0202
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0078 0.0078
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0008 0.0002 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0057 0.0202 0.0202
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0041 0.0041
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0118 0.0859
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Brugia malayi G-protein coupled receptor 0.0011 0.0015 0.0015
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0016 0.0032 0.0032
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0063 0.0063
Echinococcus granulosus lamin dm0 0.0032 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Schistosoma mansoni neuropeptide receptor 0.0011 0.0015 0.0015
Onchocerca volvulus 0.0011 0.0015 0.0111
Schistosoma mansoni ferritin light chain 0.001 0.0009 0.0009
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0313 0.1254 0.1254
Onchocerca volvulus 0.0011 0.0015 0.0111
Echinococcus granulosus neuropeptides capa receptor 0.0011 0.0015 0.0015
Brugia malayi SPARC precursor 0.0022 0.006 0.006
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0063 0.0063
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Plasmodium vivax SET domain protein, putative 0.0037 0.0118 0.0118
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0343 0.1378 0.1379
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0283 0.0283
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0063 0.0063
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0008 0.0002 0.0016
Echinococcus granulosus tm gpcr rhodopsin 0.0011 0.0015 0.0015
Echinococcus granulosus serotonin receptor 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0033 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.2095 0.8581 0.8591
Loa Loa (eye worm) hypothetical protein 0.0032 0.0099 0.0099
Loa Loa (eye worm) melatonin receptor type 1A 0.0011 0.0015 0.0015
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0011 0.0015 0.0015
Brugia malayi tailless protein 0.0027 0.0078 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0063 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0096 0.0096
Trypanosoma cruzi heat shock protein 90, putative 0.003 0.0093 0.0093
Loa Loa (eye worm) FKBP5 protein 0.2437 0.9989 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0057 0.0202 0.0202
Mycobacterium tuberculosis Bacterioferritin BfrB 0.001 0.0009 0.0065
Schistosoma mansoni amine GPCR 0.0011 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0141 0.0141
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0011 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0051
Trypanosoma brucei DNA polymerase IV, putative 0.0048 0.0166 0.0166
Loa Loa (eye worm) DR-78 0.0027 0.0078 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0118 0.0118
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) phosphatidylinositol 3 0.0053 0.0185 0.0185
Schistosoma mansoni immunophilin 0.244 1 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0202 0.0202
Loa Loa (eye worm) beta-lactamase 0.0043 0.0146 0.0146
Echinococcus multilocularis follistatin 0.0022 0.006 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0053
Onchocerca volvulus 0.0043 0.0146 0.1054
Leishmania major heat shock protein 83-1 0.0038 0.0125 0.0125
Toxoplasma gondii heat shock protein 75, putative 0.0016 0.0032 0.0235
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0015 0.0015
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0011 0.0015 0.0015
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.0063 0.0063
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0313 0.1254 0.1256
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0063 0.0063
Plasmodium vivax serine/threonine protein phosphatase 2B catalytic subunit A, putative 0.0313 0.1254 0.1256
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0057 0.0202 0.0202
Echinococcus granulosus Solute carrier organic anion transporter family 0.0033 0.0103 0.0103
Schistosoma mansoni neuropeptide F-like receptor 0.0011 0.0015 0.0015
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0343 0.1378 1
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0392 0.158 0.1581
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.2438 0.9991 1
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0343 0.1378 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0048 0.0048
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0008 0.0002 0.0002
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0057 0.0202 0.0202
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0057 0.0202 0.0202
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0051
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.2437 0.9989 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0017 0.0038 0.0038
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0011 0.0015 0.0015
Leishmania major peptidylprolyl isomerase-like protein 0.2437 0.9989 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0041 0.0041
Onchocerca volvulus 0.0033 0.0103 0.0743
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0051
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0057 0.0202 0.0202
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0343 0.1378 1
Echinococcus multilocularis neuropeptide receptor A26 0.0011 0.0015 0.0015
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.003 0.0093 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0057 0.0202 0.0202
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0092 0.0092
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0202 0.0202
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0092 0.0092
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0008 0.0002 0.0016
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0057 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Schistosoma mansoni steroid hormone receptor ad4bp 0.0057 0.0202 0.0202
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0146 0.0146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0015 0.0015
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0009 0.0009
Loa Loa (eye worm) cytochrome P450 0.0008 0.0002 0.0002
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0016 0.0032 0.0234
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0343 0.1378 0.138
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.025 0.0997 0.0998
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.006 0.0435
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0061 0.0061
Echinococcus multilocularis FTZ F1 alpha 0.0057 0.0202 0.0202
Plasmodium falciparum splicing factor 3B subunit 3, putative 0.0033 0.0103 0.0103

Activities

Activity type Activity value Assay description Source Reference
Log Ki (binding) = 8.57 D4 Ability to displace [3H]-spiperone from dopamine receptor D4.4 expressed in CHO-K1 cells ChEMBL. 11312915

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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