Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0051 | 0.0173 | 0.0219 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0166 | 0.0627 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.0446 | 0.0566 |
Trypanosoma brucei | ISWI complex protein | 0.0097 | 0.0448 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.0229 | 0.0133 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.026 | 0.1447 | 0.1835 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0163 | 0.0852 | 0.1081 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0041 | 0.0109 | 0.0014 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0249 | 0.138 | 0.5961 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.004 | 0.0104 | 0.0088 |
Toxoplasma gondii | WD domain, G-beta repeat-containing protein | 0.004 | 0.0104 | 0.0034 |
Trypanosoma brucei | trypanothione reductase | 0.0041 | 0.0106 | 0.0153 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0188 | 0.1009 | 0.4334 |
Plasmodium vivax | SET domain protein, putative | 0.0188 | 0.1009 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0061 | 0.0229 | 0.0133 |
Brugia malayi | hypothetical protein | 0.0095 | 0.0438 | 0.0556 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Plasmodium vivax | hypothetical protein, conserved | 0.0123 | 0.0609 | 0.5591 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0173 | 0.0219 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0041 | 0.0106 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0173 | 0.0657 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0061 | 0.0229 | 0.5129 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0229 | 0.029 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0208 | 0.1126 | 0.1144 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0182 | 0.0967 | 0.1419 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0142 | 0.0728 | 0.0633 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0229 | 0.029 |
Brugia malayi | Heterochromatin protein 1 | 0.037 | 0.212 | 0.2689 |
Brugia malayi | PHD-finger family protein | 0.0157 | 0.0819 | 0.1039 |
Echinococcus multilocularis | chromobox protein 2 | 0.0061 | 0.0229 | 0.0129 |
Echinococcus multilocularis | GPCR, family 2 | 0.0051 | 0.0173 | 0.0073 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.0229 | 0.0133 |
Loa Loa (eye worm) | helicase | 0.0061 | 0.0229 | 0.029 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.1667 | 0.2115 |
Toxoplasma gondii | chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 | 0.0061 | 0.0229 | 0.1408 |
Echinococcus multilocularis | Chromo domain | 0.0061 | 0.0229 | 0.0129 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0111 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0173 | 0.0657 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0101 | 0.0128 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0152 | 0.0788 | 0.3359 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Plasmodium vivax | glutathione reductase, putative | 0.0041 | 0.0106 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0852 | 0.1081 |
Plasmodium falciparum | phd finger protein, putative | 0.0123 | 0.0609 | 1 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0111 | 0.001 |
Brugia malayi | glutathione reductase | 0.0041 | 0.0106 | 0.0135 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.0446 | 0.0349 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0108 | 0.0516 | 0.042 |
Echinococcus granulosus | Chromo domain | 0.0061 | 0.0229 | 0.021 |
Brugia malayi | Pre-SET motif family protein | 0.1314 | 0.7882 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.1039 | 0.6206 | 0.6167 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0051 | 0.0173 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0229 | 0.029 |
Onchocerca volvulus | 0.0061 | 0.0229 | 0.0254 | |
Plasmodium vivax | hypothetical protein, conserved | 0.0061 | 0.0229 | 0.1408 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0023 | 0.003 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.0229 | 0.0133 |
Entamoeba histolytica | hypothetical protein | 0.0061 | 0.0229 | 0.5129 |
Trichomonas vaginalis | chromobox protein, putative | 0.0061 | 0.0229 | 0.0133 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.037 | 0.212 | 0.2689 |
Loa Loa (eye worm) | glutathione reductase | 0.0041 | 0.0106 | 0.0135 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.041 | 0.0313 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0041 | 0.0106 | 0.2182 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.0229 | 0.0133 |
Onchocerca volvulus | 0.0163 | 0.0852 | 0.0948 | |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0103 | 0.0486 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0041 | 0.0106 | 0.0153 |
Trypanosoma cruzi | ISWI complex protein | 0.0097 | 0.0448 | 1 |
Trypanosoma cruzi | ISWI complex protein | 0.0097 | 0.0448 | 1 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0102 | 0.0343 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0061 | 0.0229 | 0.5129 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0052 | 0.0174 | 0.0074 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0041 | 0.0106 | 0.0135 |
Schistosoma mansoni | phosphatidylserine receptor | 0.004 | 0.0101 | 0.034 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0296 | 0.1667 | 0.7225 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0092 | 0.0423 | 0.8704 |
Brugia malayi | jmjC domain containing protein | 0.004 | 0.0101 | 0.0128 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0123 | 0.0609 | 0.0772 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0223 | 0.1222 | 0.136 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.0229 | 0.0133 |
Plasmodium falciparum | conserved Plasmodium membrane protein, unknown function | 0.004 | 0.0104 | 0.006 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0061 | 0.0229 | 0.029 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.0173 | 0.0073 |
Brugia malayi | PHD-finger family protein | 0.0123 | 0.0609 | 0.0772 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0163 | 0.0852 | 0.1081 |
Schistosoma mansoni | hypothetical protein | 0.0111 | 0.0538 | 0.2261 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0229 | 0.029 |
Brugia malayi | chromobox protein homolog 3 | 0.0208 | 0.1126 | 0.1429 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0111 | 0.014 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0173 | 0.0657 |
Brugia malayi | MH2 domain containing protein | 0.026 | 0.1447 | 0.1835 |
Brugia malayi | CHD4 protein | 0.0073 | 0.0302 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0167 | 0.0212 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0059 | 0.022 | 0.0279 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0073 | 0.0302 | 0.1226 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0 | 0.5 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0 | 0.5 |
Schistosoma mansoni | chromobox protein | 0.037 | 0.212 | 0.9216 |
Echinococcus granulosus | jumonji domain containing protein | 0.0171 | 0.0903 | 0.1313 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.1126 | 0.1429 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.0173 | 0.0073 |
Echinococcus granulosus | chromobox protein 2 | 0.0061 | 0.0229 | 0.021 |
Schistosoma mansoni | jumonji domain containing protein | 0.032 | 0.1811 | 0.7857 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0123 | 0.0609 | 0.0832 |
Echinococcus granulosus | Chromobox protein 3 | 0.0061 | 0.0229 | 0.021 |
Echinococcus granulosus | chromobox protein 1 | 0.037 | 0.212 | 0.3307 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0102 | 0.0343 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0166 | 0.0066 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0061 | 0.0229 | 0.0902 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0092 | 0.0423 | 0.8704 |
Schistosoma mansoni | hypothetical protein | 0.0097 | 0.0448 | 0.1868 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0061 | 0.0229 | 0.0902 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0438 | 0.0556 |
Echinococcus granulosus | zinc finger protein | 0.0124 | 0.0613 | 0.084 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0171 | 0.0903 | 0.081 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.026 | 0.1447 | 0.1835 |
Brugia malayi | jmjC domain containing protein | 0.004 | 0.0101 | 0.0128 |
Echinococcus multilocularis | zinc finger protein | 0.0124 | 0.0613 | 0.0518 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0103 | 0.0486 | 1 |
Brugia malayi | AF-10 protein | 0.004 | 0.0104 | 0.0132 |
Schistosoma mansoni | chromobox protein | 0.0061 | 0.0229 | 0.0902 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0146 | 0.0046 |
Schistosoma mansoni | hypothetical protein | 0.0061 | 0.0229 | 0.0902 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.0609 | 0.2573 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.004 | 0.0101 | 0.0128 |
Brugia malayi | Pre-SET motif family protein | 0.0188 | 0.1009 | 0.1281 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0102 | 0.0343 |
Entamoeba histolytica | hypothetical protein | 0.0061 | 0.0229 | 0.5129 |
Toxoplasma gondii | 'chromo' (CHRromatin Organization MOdifier) domain-containing protein | 0.0061 | 0.0229 | 0.1408 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0061 | 0.0229 | 0.0129 |
Entamoeba histolytica | hypothetical protein | 0.0061 | 0.0229 | 0.5129 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0098 | 0.0455 | 0.1897 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0112 | 0.054 | 0.0685 |
Trichomonas vaginalis | chromobox protein, putative | 0.0061 | 0.0229 | 0.0133 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0073 | 0.0302 | 0.0204 |
Brugia malayi | M-phase phosphoprotein, mpp8 | 0.0061 | 0.0229 | 0.029 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0103 | 0.0486 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0166 | 0.0627 |
Giardia lamblia | PHD finger protein 15 | 0.0123 | 0.0609 | 0.5 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0052 | 0.0174 | 0.0121 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0163 | 0.0852 | 0.1081 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0161 | 0.084 | 0.3591 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0229 | 0.029 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0061 | 0.0229 | 0.5129 |
Onchocerca volvulus | 0.0152 | 0.0788 | 0.0876 | |
Schistosoma mansoni | eyes absent homolog | 0.0095 | 0.0438 | 0.1824 |
Onchocerca volvulus | 0.1495 | 0.8991 | 1 | |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0092 | 0.0423 | 0.8704 |
Loa Loa (eye worm) | hypothetical protein | 0.0211 | 0.1145 | 0.1452 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0166 | 0.0107 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0254 | 0.1408 | 0.1786 |
Brugia malayi | SET domain containing protein | 0.0068 | 0.0271 | 0.0344 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0446 | 0.0566 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0161 | 0.084 | 0.1211 |
Trichomonas vaginalis | chromobox protein, putative | 0.037 | 0.212 | 0.2263 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.004 | 0.0101 | 0.0128 |
Schistosoma mansoni | bromodomain containing protein | 0.0399 | 0.2298 | 1 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0104 | 0.0353 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0377 | 0.216 | 0.3373 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0402 | 0.2316 | 0.3628 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.1314 | 0.7882 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0296 | 0.1667 | 0.2565 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.0654 | 0.2772 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0166 | 0.0211 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0137 | 0.0698 | 0.0603 |
Echinococcus granulosus | tumor protein p63 | 0.1039 | 0.6206 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0097 | 0.0448 | 0.1868 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0188 | 0.1009 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0227 | 0.1244 | 0.1872 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0173 | 0.0657 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0149 | 0.0767 | 0.0673 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0227 | 0.1244 | 0.1155 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.0229 | 0.0133 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0166 | 0.0627 |
Trichomonas vaginalis | hypothetical protein | 0.0061 | 0.0229 | 0.0133 |
Trichomonas vaginalis | Heterochromatin protein, putative | 0.0061 | 0.0229 | 0.0133 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0377 | 0.216 | 0.208 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Schistosoma mansoni | protein phosphatase 2C | 0.004 | 0.0101 | 0.034 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0296 | 0.1667 | 0.1582 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0103 | 0.0486 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0051 | 0.0173 | 0.0219 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0208 | 0.1126 | 0.1253 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0137 | 0.0698 | 0.0978 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0161 | 0.084 | 0.1066 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0852 | 0.1081 |
Schistosoma mansoni | jumonji domain containing protein | 0.004 | 0.0101 | 0.034 |
Schistosoma mansoni | chromobox protein | 0.0061 | 0.0229 | 0.0902 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.0173 | 0.0118 |
Brugia malayi | Bromodomain containing protein | 0.0242 | 0.1335 | 0.1694 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0041 | 0.0109 | 0.0009 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0123 | 0.0609 | 0.0513 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0142 | 0.0728 | 0.1027 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0123 | 0.0609 | 0.2573 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0147 | 0.0756 | 0.0727 |
Toxoplasma gondii | thioredoxin reductase | 0.0041 | 0.0106 | 0.0059 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0402 | 0.2316 | 0.2237 |
Brugia malayi | Protein cec-1. | 0.0061 | 0.0229 | 0.029 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Brugia malayi | jmjC domain containing protein | 0.004 | 0.0101 | 0.0128 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0111 | 0.014 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0108 | 0.0516 | 0.2165 |
Echinococcus granulosus | GPCR family 2 | 0.0051 | 0.0173 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.0788 | 0.0999 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0092 | 0.0423 | 0.8704 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0061 | 0.0229 | 0.2518 |
Echinococcus granulosus | chromobox protein 1 | 0.037 | 0.212 | 0.3307 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0111 | 0.001 |
Brugia malayi | Bromodomain containing protein | 0.0473 | 0.275 | 0.3489 |
Brugia malayi | jmjC domain containing protein | 0.0402 | 0.2316 | 0.2938 |
Onchocerca volvulus | 0.0061 | 0.0229 | 0.0254 | |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0061 | 0.0229 | 0.0902 |
Brugia malayi | PHD-finger family protein | 0.0052 | 0.0177 | 0.0225 |
Brugia malayi | jmjC domain containing protein | 0.0161 | 0.084 | 0.1066 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0296 | 0.1667 | 0.7225 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Mycobacterium tuberculosis | Probable reductase | 0.0092 | 0.0423 | 0.8704 |
Echinococcus multilocularis | chromobox protein 1 | 0.037 | 0.212 | 0.204 |
Brugia malayi | Bromodomain containing protein | 0.0138 | 0.07 | 0.0888 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0108 | 0.0516 | 0.068 |
Leishmania major | trypanothione reductase | 0.0041 | 0.0106 | 0.2365 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0061 | 0.0229 | 0.0133 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.0173 | 0.0118 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0166 | 0.0066 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0111 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.1338 | 0.1697 |
Schistosoma mansoni | chromobox protein | 0.037 | 0.212 | 0.9216 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0142 | 0.0728 | 0.3096 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0061 | 0.0229 | 0.0129 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0147 | 0.0756 | 0.0727 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0123 | 0.0609 | 0.5591 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0111 | 0.0383 |
Trichomonas vaginalis | chromobox protein, putative | 0.0223 | 0.1222 | 0.1252 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0161 | 0.084 | 0.3591 |
Echinococcus multilocularis | peregrin | 0.0138 | 0.07 | 0.0605 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.004 | 0.0101 | 0.034 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.0538 | 0.0682 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0061 | 0.0229 | 0.029 |
Brugia malayi | Valyl-tRNA synthetase | 0.0061 | 0.0229 | 0.029 |
Plasmodium falciparum | heterochromatin protein 1 | 0.0061 | 0.0229 | 0.2518 |
Trichomonas vaginalis | set domain proteins, putative | 0.1495 | 0.8991 | 1 |
Plasmodium vivax | heterochromatin protein 1, putative | 0.0061 | 0.0229 | 0.1408 |
Trichomonas vaginalis | chromobox protein, putative | 0.0223 | 0.1222 | 0.1252 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.0446 | 1 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0102 | 0.0343 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 0.1503 | 0.1907 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0073 | 0.0302 | 0.0384 |
Plasmodium falciparum | chromodomain-helicase-DNA-binding protein 1 homolog, putative | 0.0061 | 0.0229 | 0.2518 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0 | 0.5 |
Toxoplasma gondii | 'chromo' (CHRromatin Organization MOdifier) domain-containing protein | 0.0061 | 0.0229 | 0.1408 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.0446 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.1429 | 0.1813 |
Leishmania major | hypothetical protein, conserved | 0.0097 | 0.0448 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0041 | 0.0106 | 0.0105 |
Brugia malayi | hypothetical protein | 0.0061 | 0.0229 | 0.029 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0092 | 0.0423 | 0.8704 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.004 | 0.0104 | 0.0034 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0092 | 0.0423 | 0.8704 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0229 | 0.029 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0111 | 0.0538 | 0.0682 |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.041 | 0.0507 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0166 | 0.0107 |
Loa Loa (eye worm) | PHD-finger family protein | 0.013 | 0.0654 | 0.083 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0208 | 0.1126 | 0.1144 |
Plasmodium vivax | hypothetical protein, conserved | 0.004 | 0.0104 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0177 | 0.0225 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0166 | 0.0211 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0073 | 0.0302 | 0.033 |
Plasmodium vivax | hypothetical protein, conserved | 0.0061 | 0.0229 | 0.1408 |
Schistosoma mansoni | phd/f-box containing protein | 0.004 | 0.0101 | 0.034 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.004 | 0.0104 | 0.0088 |
Onchocerca volvulus | 0.0249 | 0.138 | 0.1534 | |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0061 | 0.0229 | 0.021 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.0229 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0438 | 0.0556 |
Loa Loa (eye worm) | hypothetical protein | 0.0446 | 0.2585 | 0.328 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0229 | 0.029 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0188 | 0.1009 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0101 | 0.0128 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.0229 | 0.0133 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0123 | 0.0609 | 0.5591 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.004 | 0.0101 | 0.0128 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.0609 | 0.0772 |
Brugia malayi | jmjC domain containing protein | 0.004 | 0.0101 | 0.0128 |
Leishmania major | hypothetical protein, conserved | 0.004 | 0.0101 | 0.2247 |
Onchocerca volvulus | Alhambra homolog | 0.0123 | 0.0609 | 0.0677 |
Schistosoma mansoni | zinc finger protein | 0.0124 | 0.0613 | 0.2593 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0108 | 0.0516 | 0.2165 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0047 | 0.0146 | 0.0539 |
Trichomonas vaginalis | chromobox protein, putative | 0.037 | 0.212 | 0.2263 |
Plasmodium falciparum | thioredoxin reductase | 0.0041 | 0.0106 | 0.0105 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.0229 | 0.0133 |
Brugia malayi | Thioredoxin reductase | 0.0041 | 0.0106 | 0.0135 |
Echinococcus multilocularis | chromobox protein 1 | 0.037 | 0.212 | 0.204 |
Echinococcus granulosus | peregrin | 0.0138 | 0.07 | 0.0982 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0111 | 0.014 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Change in reaction time (functional) | = 20 % | Analgesic activity of the compound (0.5ug icv) tested after 60min, in mice tail-flick test | ChEMBL. | 3339602 |
Change in reaction time (functional) | = 22 % | Analgesic activity of the compound (0.5ug icv) tested after 30min, in mice tail-flick test | ChEMBL. | 3339602 |
Change in reaction time (functional) | = 37 % | Analgesic activity of the compound (0.5ug icv) tested after 5min, in mice tail-flick test | ChEMBL. | 3339602 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.