Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0094 | 0.2302 | 0.2292 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0282 | 0.1159 |
Echinococcus granulosus | GPCR family 2 | 0.0066 | 0.1457 | 0.1445 |
Echinococcus multilocularis | protein dispatched 1 | 0.0068 | 0.1528 | 0.1517 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0163 | 0.4367 | 0.436 |
Plasmodium falciparum | thioredoxin reductase | 0.0049 | 0.0961 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0282 | 0.0373 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0112 | 0.2849 | 0.4276 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0078 | 0.1813 | 1 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0018 | 0.0017 | 0.0004 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.057 | 0.3079 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0219 | 0.0456 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0034 | 0.0509 | 0.0497 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0034 | 0.0509 | 0.1113 |
Brugia malayi | N-terminal motif family protein | 0.0188 | 0.5114 | 0.7088 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0068 | 0.1528 | 0.8414 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0609 | 0.0827 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0112 | 0.2849 | 0.8752 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0609 | 0.1304 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0034 | 0.0509 | 0.0497 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0018 | 0.0005 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0899 | 0.0887 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0094 | 0.2302 | 0.2292 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0112 | 0.2849 | 0.4276 |
Brugia malayi | MH2 domain containing protein | 0.0258 | 0.7214 | 1 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0034 | 0.0509 | 0.0497 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0188 | 0.5114 | 1 |
Echinococcus multilocularis | caspase | 0.0018 | 0.0017 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0188 | 0.5114 | 0.7083 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0018 | 0.0005 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0899 | 0.0887 |
Schistosoma mansoni | patched 1 | 0.0068 | 0.1528 | 0.1517 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.0165 | 0.4444 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0219 | 0.042 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.1457 | 0.1445 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0207 | 0.5712 | 0.7918 |
Schistosoma mansoni | hypothetical protein | 0.035 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0163 | 0.4367 | 0.436 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.1457 | 0.1445 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0282 | 0.2807 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0018 | 0.0018 | 0.0005 |
Mycobacterium tuberculosis | Probable reductase | 0.0112 | 0.2849 | 0.4276 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.0165 | 0.4444 | 0.4437 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0219 | 0.0323 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0142 | 0.3743 | 0.5188 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0683 | 0.093 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.4444 | 0.6153 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0609 | 0.2591 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0034 | 0.0509 | 0.1113 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0068 | 0.1528 | 0.1517 |
Leishmania major | trypanothione reductase | 0.0049 | 0.0961 | 0.2132 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0219 | 0.042 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0609 | 0.091 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.057 | 0.3079 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0066 | 0.1457 | 0.2004 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0721 | 0.0999 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0609 | 0.1338 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.0165 | 0.4444 | 0.6161 |
Plasmodium vivax | glutathione reductase, putative | 0.0049 | 0.0961 | 1 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0068 | 0.1528 | 0.1517 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0282 | 0.2807 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.057 | 0.1962 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.057 | 0.3079 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0219 | 0.042 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0239 | 0.6657 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0207 | 0.5712 | 0.7918 |
Schistosoma mansoni | bromodomain containing protein | 0.0066 | 0.1459 | 0.1448 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1457 | 0.2004 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0219 | 0.0285 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.5712 | 0.7914 |
Onchocerca volvulus | 0.0037 | 0.0609 | 0.0797 | |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0189 | 0.0176 |
Onchocerca volvulus | 0.0037 | 0.0609 | 0.0797 | |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0018 | 0.0018 | 0.0005 |
Echinococcus multilocularis | caspase 2 | 0.0059 | 0.1251 | 0.1239 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0219 | 0.042 |
Brugia malayi | CHE-14 protein | 0.0068 | 0.1528 | 0.2118 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0899 | 0.0887 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0125 | 0.3224 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0609 | 0.091 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0609 | 0.091 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0219 | 0.042 |
Schistosoma mansoni | hypothetical protein | 0.0142 | 0.3743 | 0.3734 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0609 | 0.1338 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.057 | 0.0773 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0018 | 0.0017 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0609 | 0.0827 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0899 | 0.0887 |
Trypanosoma brucei | trypanothione reductase | 0.0049 | 0.0961 | 0.2132 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0066 | 0.1457 | 0.1445 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1691 | 0.233 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0018 | 0.0017 | 0.0004 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0609 | 0.091 |
Schistosoma mansoni | hypothetical protein | 0.035 | 1 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0112 | 0.2849 | 0.4276 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0034 | 0.0509 | 0.0497 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0816 | 0.1115 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0609 | 0.0844 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0609 | 0.0597 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0068 | 0.1528 | 0.1517 |
Echinococcus multilocularis | protein patched | 0.0068 | 0.1528 | 0.1517 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0609 | 0.1299 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0112 | 0.2849 | 0.4276 |
Echinococcus granulosus | caspase | 0.0018 | 0.0017 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.1251 | 0.1719 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0609 | 0.0597 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0097 | 0.0084 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0165 | 0.4444 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0219 | 0.042 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.0165 | 0.4444 | 0.4437 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0028 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0097 | 0.0084 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0066 | 0.1457 | 0.1445 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0609 | 0.0827 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0018 | 0.0018 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0028 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0066 | 0.1457 | 0.1445 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0049 | 0.0961 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0066 | 0.1457 | 0.2019 |
Echinococcus multilocularis | caspase 8 | 0.0018 | 0.0017 | 0.0004 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0059 | 0.1251 | 0.2109 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0049 | 0.0961 | 0.2132 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0125 | 0.3224 | 0.484 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0609 | 0.0827 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.057 | 0.242 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0034 | 0.0509 | 0.0497 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0018 | 0.0017 | 0.0004 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0037 | 0.0034 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0609 | 0.0597 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0028 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0084 | 0.2008 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0757 | 0.1032 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0207 | 0.5712 | 0.7914 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0219 | 0.0456 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0609 | 0.091 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0028 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0609 | 0.1304 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0049 | 0.0961 | 0.1438 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0609 | 0.3298 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0034 | 0.5 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0094 | 0.2302 | 0.2292 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0034 | 0.0509 | 0.1113 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0219 | 0.0456 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0609 | 0.1338 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.1457 | 0.1445 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0068 | 0.1528 | 0.2103 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0609 | 0.091 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0165 | 0.4444 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0607 | 0.0594 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0068 | 0.1528 | 0.1517 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0084 | 0.2008 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0163 | 0.4367 | 0.436 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0282 | 0.0598 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0609 | 0.091 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0609 | 0.0844 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0609 | 0.3298 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0282 | 0.0598 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0721 | 0.0983 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0609 | 0.0827 |
Echinococcus multilocularis | GPCR, family 2 | 0.0066 | 0.1457 | 0.1445 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.057 | 0.0557 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0609 | 0.1304 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0094 | 0.2302 | 0.2292 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0189 | 0.0176 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0263 | 0.0365 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0018 | 0.0007 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0094 | 0.2302 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0609 | 0.3298 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0125 | 0.3224 | 0.484 |
Brugia malayi | Smad1 | 0.0018 | 0.0013 | 0.0018 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0034 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.2008 | 0.277 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0189 | 0.0176 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0899 | 0.1246 |
Plasmodium falciparum | glutathione reductase | 0.0049 | 0.0961 | 1 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0034 | 0.0509 | 0.076 |
Onchocerca volvulus | 0.0037 | 0.0609 | 0.0797 | |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0219 | 0.0323 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.3688 | 0.3679 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0082 | 0.1959 | 0.1949 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0609 | 0.0827 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0609 | 0.3298 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.013 | 0.0117 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0609 | 0.091 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0078 | 0.1813 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0049 | 0.0961 | 0.1316 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0165 | 0.4444 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0018 | 0.0013 | 0.0018 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0899 | 0.0887 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0899 | 0.123 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0017 | 0.0005 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.057 | 0.3079 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0219 | 0.042 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0034 | 0.0509 | 0.5219 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0018 | 0.0017 | 0.0004 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.057 | 0.3079 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0609 | 0.0844 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.057 | 0.3079 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0034 | 0.0509 | 0.0497 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0609 | 0.1338 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0899 | 0.0887 |
Brugia malayi | Thioredoxin reductase | 0.0049 | 0.0961 | 0.1332 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.057 | 0.3079 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0066 | 0.1457 | 0.2019 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0097 | 0.0084 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0034 | 0.0179 |
Brugia malayi | Isocitrate dehydrogenase | 0.0034 | 0.0509 | 0.0706 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0258 | 0.7214 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0258 | 0.7214 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0609 | 0.3298 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0609 | 0.1299 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0219 | 0.0285 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0034 | 0.0509 | 0.0689 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0078 | 0.1813 | 1 |
Echinococcus granulosus | caspase 8 | 0.0018 | 0.0017 | 0.0004 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0018 | 0.0018 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1528 | 0.2103 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0282 | 0.0598 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0282 | 0.0598 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.057 | 0.1249 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0062 | 0.1348 | 0.1336 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0163 | 0.4367 | 0.6046 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0082 | 0.1959 | 0.2716 |
Onchocerca volvulus | 0.0094 | 0.2309 | 0.4271 | |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.0681 | 0.0943 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0899 | 0.0887 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.057 | 0.1249 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0041 | 0.0721 | 0.0709 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0066 | 0.1457 | 0.1445 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0082 | 0.1959 | 0.2702 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.057 | 0.1962 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0165 | 0.4444 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.057 | 0.3079 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0219 | 0.0303 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0034 | 0.0179 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0034 | 0.0509 | 0.2156 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.3688 | 0.3679 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0282 | 0.2807 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0609 | 0.3298 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0609 | 0.1304 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0219 | 0.0285 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.2302 | 0.3178 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0609 | 0.091 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.0165 | 0.4444 | 0.4437 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0034 | 0.0509 | 0.5219 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0028 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.057 | 0.1249 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0609 | 0.1304 |
Echinococcus granulosus | caspase 2 | 0.0059 | 0.1251 | 0.1239 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0082 | 0.1959 | 0.1949 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0049 | 0.0961 | 0.0949 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0609 | 0.0827 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0282 | 0.0391 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0018 | 0.0005 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.013 | 0.0162 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0163 | 0.4367 | 0.6053 |
Onchocerca volvulus | 0.0041 | 0.0721 | 0.1026 | |
Brugia malayi | isocitrate dehydrogenase | 0.0034 | 0.0509 | 0.0706 |
Brugia malayi | MH2 domain containing protein | 0.0018 | 0.0013 | 0.0018 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0059 | 0.1251 | 0.1239 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0112 | 0.2849 | 0.4276 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0068 | 0.1528 | 0.1517 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0609 | 0.6275 |
Brugia malayi | Bromodomain containing protein | 0.0078 | 0.1824 | 0.2529 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0041 | 0.0721 | 0.0709 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0219 | 0.0303 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0094 | 0.2302 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0125 | 0.3224 | 0.484 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0609 | 0.0827 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.057 | 0.0557 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0721 | 0.0709 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0068 | 0.1528 | 0.1517 |
Echinococcus multilocularis | geminin | 0.035 | 1 | 1 |
Brugia malayi | glutathione reductase | 0.0049 | 0.0961 | 0.1332 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0609 | 0.091 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0034 | 0.0509 | 0.0497 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0049 | 0.0961 | 0.0949 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0219 | 0.0303 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0062 | 0.1348 | 0.1336 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0034 | 0.0509 | 0.2156 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0607 | 0.0594 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.057 | 0.1249 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0609 | 0.0597 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.057 | 0.0557 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0018 | 0.0005 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.057 | 0.3079 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0034 | 0.0509 | 0.1113 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0049 | 0.0961 | 0.1316 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0609 | 0.0844 |
Brugia malayi | MH1 domain containing protein | 0.0018 | 0.0013 | 0.0018 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0034 | 0.0509 | 0.1113 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.3743 | 0.5179 |
Brugia malayi | MH2 domain containing protein | 0.0018 | 0.0013 | 0.0018 |
Toxoplasma gondii | thioredoxin reductase | 0.0049 | 0.0961 | 0.413 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.1457 | 0.1445 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0018 | 0.0017 | 0.0023 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0094 | 0.2302 | 0.2292 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.057 | 0.079 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0219 | 0.042 |
Brugia malayi | Cell death protein 3 precursor | 0.0059 | 0.1251 | 0.1734 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 3 nM | In vitro inhibition of solubilized HMG-CoA reductase in rat liver. | ChEMBL. | 1656041 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.