Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4688 | 0.4688 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.2153 | 0.1681 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.2153 | 0.2203 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.7469 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.8077 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0127 | 0.0127 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2153 | 0.2153 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2153 | 0.2153 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Onchocerca volvulus | 0.0029 | 0.4403 | 0.5 | |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.2153 | 0.2203 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0956 | 0.0446 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.7469 | 0.9149 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.7469 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.4403 | 0.4856 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.7469 | 1 |
Plasmodium falciparum | zinc finger protein, putative | 0.0003 | 0 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.2153 | 0.1704 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2153 | 0.2153 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.4403 | 0.4403 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.5335 | 0.616 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0651 | 0.0651 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.8077 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0956 | 0.0446 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.4688 | 0.5921 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.2153 | 0.1681 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.2153 | 0.2203 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.7469 | 0.7469 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.5335 | 0.5335 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4688 | 0.4688 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.2153 | 0.2203 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.2153 | 0.2203 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.7469 | 0.9146 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.2153 | 0.1704 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.7469 | 0.7469 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.5335 | 0.615 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2153 | 0.2153 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.4403 | 0.4842 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.8077 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.2153 | 0.2203 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.7469 | 0.7469 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.4688 | 0.5921 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.8077 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.8869 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.7469 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.