Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0114 | 0.0988 | 0.2622 | |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0151 | 0.1472 | 0.1851 |
Loa Loa (eye worm) | pyruvate kinase | 0.004 | 0.0037 | 0.0005 |
Brugia malayi | tailless protein | 0.0151 | 0.1472 | 0.1444 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0151 | 0.1472 | 0.1444 |
Onchocerca volvulus | 0.0151 | 0.1472 | 0.3958 | |
Echinococcus granulosus | jumonji domain containing protein | 0.0046 | 0.011 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.004 | 0.0037 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0169 | 0.1706 | 0.4613 |
Brugia malayi | hypothetical protein | 0.0169 | 0.1706 | 0.1679 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0151 | 0.1472 | 0.1444 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0151 | 0.1472 | 0.3966 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0321 | 0.3662 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0321 | 0.3662 | 0.3641 |
Schistosoma mansoni | alpha glucosidase | 0.0044 | 0.0081 | 0.0134 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0321 | 0.3662 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0325 | 0.0293 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0321 | 0.3662 | 0.3641 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0811 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0169 | 0.1706 | 0.1679 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0151 | 0.1472 | 0.1851 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0197 | 0.206 | 0.2034 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0044 | 0.0081 | 1 |
Onchocerca volvulus | 0.0321 | 0.3662 | 1 | |
Schistosoma mansoni | nuclear hormone receptor | 0.0151 | 0.1472 | 0.3966 |
Brugia malayi | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0321 | 0.3662 | 0.3641 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0321 | 0.3662 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0151 | 0.1472 | 0.1444 |
Schistosoma mansoni | nuclear receptor | 0.0151 | 0.1472 | 0.3966 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0169 | 0.1706 | 0.1679 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0151 | 0.1472 | 0.3966 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0055 | 0.0231 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.004 | 0.0037 | 0.0005 |
Brugia malayi | ecdysone receptor | 0.0151 | 0.1472 | 0.1444 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0169 | 0.1706 | 0.2152 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0057 | 0.4382 |
Brugia malayi | ecdysteroid receptor | 0.0321 | 0.3662 | 0.3641 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0151 | 0.1472 | 0.1444 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0321 | 0.3662 | 0.3641 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.004 | 0.0037 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0044 | 0.0081 | 0.0049 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0042 | 0.0057 | 0.4382 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0044 | 0.0081 | 1 |
Echinococcus granulosus | potassium channel KvQLT family member kqt 1 | 0.0139 | 0.1312 | 0.1646 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0231 | 0.0546 |
Trypanosoma brucei | glucosidase, putative | 0.0044 | 0.0081 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.0057 | 0.4382 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0321 | 0.3662 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0037 | 0.0005 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0151 | 0.1472 | 0.1851 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0247 | 0.0215 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0151 | 0.1472 | 0.3966 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0321 | 0.3662 | 0.4666 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0321 | 0.3662 | 0.3641 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0231 | 0.0546 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0321 | 0.3662 | 0.3641 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0231 | 0.0255 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0321 | 0.3662 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0044 | 0.0081 | 1 |
Brugia malayi | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Plasmodium vivax | pyruvate kinase, putative | 0.004 | 0.0037 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0321 | 0.3662 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0151 | 0.1472 | 0.3966 |
Echinococcus multilocularis | potassium voltage gated channel subfamily KQT | 0.0062 | 0.0325 | 0.0805 |
Echinococcus granulosus | pyruvate kinase | 0.004 | 0.0037 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0321 | 0.3662 | 1 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0151 | 0.1472 | 0.3966 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0321 | 0.3662 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.3662 | 0.3641 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0321 | 0.3662 | 0.3641 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0321 | 0.3662 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0057 | 0.4382 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Echinococcus multilocularis | pyruvate kinase | 0.004 | 0.0037 | 0.0014 |
Loa Loa (eye worm) | inositol-1 | 0.0042 | 0.0057 | 0.0024 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0044 | 0.0081 | 0.0062 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0321 | 0.3662 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0151 | 0.1472 | 0.1444 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0321 | 0.3662 | 0.3641 |
Onchocerca volvulus | 0.0151 | 0.1472 | 0.3958 | |
Brugia malayi | Nuclear hormone receptor E75 | 0.0151 | 0.1472 | 0.1444 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0108 | 0.0912 | 0.2424 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0169 | 0.1706 | 0.1679 |
Brugia malayi | conserved hypotetical protein | 0.0151 | 0.1472 | 0.1444 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0044 | 0.0081 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1706 | 0.1679 |
Plasmodium falciparum | pyruvate kinase | 0.004 | 0.0037 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0231 | 0.0546 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0321 | 0.3662 | 0.3641 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0151 | 0.1472 | 0.1444 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0197 | 0.206 | 0.5586 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0151 | 0.1472 | 0.3966 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0151 | 0.1472 | 0.3958 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0321 | 0.3662 | 0.3641 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.3662 | 0.3641 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0321 | 0.3662 | 0.3641 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1706 | 0.1679 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0.0081 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0042 | 0.0057 | 0.0031 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0151 | 0.1472 | 0.3958 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0044 | 0.0081 | 1 |
Loa Loa (eye worm) | pyruvate kinase | 0.004 | 0.0037 | 0.0005 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0.0081 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0055 | 0.0231 | 0.0199 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0321 | 0.3662 | 0.3641 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0321 | 0.3662 | 0.3641 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0042 | 0.0057 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0151 | 0.1472 | 0.3966 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0151 | 0.1472 | 0.1851 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0044 | 0.0081 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0642 | 0.781 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0321 | 0.3662 | 0.3641 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0057 | 0.4382 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.004 | 0.0037 | 0.0005 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0231 | 0.0546 |
Brugia malayi | nuclear hormone receptor | 0.0151 | 0.1472 | 0.1444 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.0057 | 0.4382 |
Echinococcus granulosus | potassium voltage gated channel subfamily KQT | 0.0062 | 0.0325 | 0.0376 |
Schistosoma mansoni | thyroid hormone receptor | 0.0321 | 0.3662 | 1 |
Schistosoma mansoni | pyruvate kinase | 0.004 | 0.0037 | 0.0014 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0321 | 0.3662 | 1 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0042 | 0.0057 | 0.0066 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0169 | 0.1706 | 0.4613 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0.0081 | 1 |
Loa Loa (eye worm) | voltage-gated potassium channel | 0.0137 | 0.1282 | 0.1254 |
Brugia malayi | Inositol-1 | 0.0042 | 0.0057 | 0.0024 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0151 | 0.1472 | 0.3966 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0321 | 0.3662 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0321 | 0.3662 | 0.3641 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0151 | 0.1472 | 0.1444 |
Schistosoma mansoni | voltage-gated potassium channel KCNQ | 0.0139 | 0.1312 | 0.3527 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0042 | 0.0057 | 0.4382 |
Brugia malayi | nuclear receptor NHR-88 | 0.0151 | 0.1472 | 0.1444 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0321 | 0.3662 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0321 | 0.3662 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0151 | 0.1472 | 0.1444 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0169 | 0.1706 | 0.4613 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0068 | 0.0397 | 0.0365 |
Schistosoma mansoni | alpha-glucosidase | 0.0169 | 0.1706 | 0.461 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0046 | 0.011 | 0.0213 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0197 | 0.206 | 0.2034 |
Brugia malayi | hypothetical protein | 0.0169 | 0.1706 | 0.1679 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0321 | 0.3662 | 0.3641 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0044 | 0.0081 | 0.0134 |
Echinococcus multilocularis | potassium voltage gated channel subfamily KQT | 0.0139 | 0.1312 | 0.3527 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.0057 | 0.0066 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0321 | 0.3662 | 0.4666 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0197 | 0.206 | 0.2606 |
Brugia malayi | nuclear receptor NHR-67 | 0.0151 | 0.1472 | 0.1444 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0044 | 0.0081 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0.0081 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0151 | 0.1472 | 0.3966 |
Loa Loa (eye worm) | DR-78 | 0.0151 | 0.1472 | 0.1444 |
Schistosoma mansoni | thyroid hormone receptor | 0.0321 | 0.3662 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0151 | 0.1472 | 0.1444 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0321 | 0.3662 | 0.4666 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0321 | 0.3662 | 0.4666 |
Echinococcus granulosus | FTZ F1 alpha | 0.0321 | 0.3662 | 0.4666 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0321 | 0.3662 | 0.4666 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0042 | 0.0057 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0044 | 0.0081 | 1 |
Echinococcus multilocularis | pyruvate kinase | 0.004 | 0.0037 | 0.0014 |
Schistosoma mansoni | jumonji domain containing protein | 0.0086 | 0.0625 | 0.1634 |
Schistosoma mansoni | nuclear receptor | 0.0151 | 0.1472 | 0.3966 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.3662 | 0.3641 |
Schistosoma mansoni | alpha-glucosidase | 0.0169 | 0.1706 | 0.461 |
Loa Loa (eye worm) | potassium voltage-gated channel subfamily Q member 5 | 0.0062 | 0.0325 | 0.0293 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0197 | 0.206 | 0.5586 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0151 | 0.1472 | 0.1851 |
Giardia lamblia | Pyruvate kinase | 0.004 | 0.0037 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0321 | 0.3662 | 0.4666 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0108 | 0.0912 | 0.1131 |
Chlamydia trachomatis | pyruvate kinase | 0.004 | 0.0037 | 0.5 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0057 | 0.4382 |
Echinococcus granulosus | pyruvate kinase | 0.004 | 0.0037 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.3662 | 0.3641 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0231 | 0.0255 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.0057 | 0.0066 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0044 | 0.0081 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0321 | 0.3662 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0321 | 0.3662 | 0.3641 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1706 | 0.1679 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0044 | 0.0081 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0321 | 0.3662 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0044 | 0.0081 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1706 | 0.1679 |
Brugia malayi | nuclear hormone receptor | 0.0321 | 0.3662 | 0.3641 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0321 | 0.3662 | 0.3641 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.3662 | 0.3641 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0231 | 0.0546 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0.0081 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0321 | 0.3662 | 0.3641 |
Brugia malayi | jmjC domain containing protein | 0.0108 | 0.0912 | 0.0883 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.3662 | 0.3641 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0321 | 0.3662 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0321 | 0.3662 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0151 | 0.1472 | 0.3966 |
Brugia malayi | nuclear receptor NHR-88 | 0.0321 | 0.3662 | 0.3641 |
Loa Loa (eye worm) | pyruvate kinase | 0.004 | 0.0037 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Schistosoma mansoni | coup transcription factor | 0.0321 | 0.3662 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0151 | 0.1472 | 0.3966 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0321 | 0.3662 | 0.4666 |
Brugia malayi | Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog | 0.0139 | 0.1312 | 0.1284 |
Schistosoma mansoni | nuclear hormone receptor | 0.0321 | 0.3662 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1706 | 0.1679 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0321 | 0.3662 | 0.3641 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.3662 | 0.3641 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0321 | 0.3662 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0321 | 0.3662 | 0.3641 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0169 | 0.1706 | 0.1679 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0321 | 0.3662 | 0.4666 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.3662 | 0.3641 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1472 | 0.1444 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0321 | 0.3662 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0321 | 0.3662 | 0.3641 |
Schistosoma mansoni | pyruvate kinase | 0.004 | 0.0037 | 0.0014 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0321 | 0.3662 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0321 | 0.3662 | 0.3641 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0325 | 0.0293 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | > 30 uM | Agonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay | ChEMBL. | 22793372 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.