Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | quiescin q6-related sulfhydryl oxidase | 0.0005 | 0.0118 | 0.0081 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.006 | 0.3607 | 0.4022 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0033 | 0.1857 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.8791 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.8791 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0142 | 0.8791 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0142 | 0.8791 | 0.8776 |
Echinococcus granulosus | muscleblind protein | 0.0142 | 0.8791 | 0.8776 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0182 | 1 |
Brugia malayi | Augmenter of liver regeneration | 0.0033 | 0.1857 | 0.2005 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0182 | 1 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.022 | 0.0102 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0182 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0325 | 0.0209 |
Echinococcus multilocularis | tar DNA binding protein | 0.006 | 0.3607 | 0.353 |
Loa Loa (eye worm) | RNA binding protein | 0.006 | 0.3607 | 0.4022 |
Brugia malayi | RNA binding protein | 0.006 | 0.3607 | 0.4022 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.006 | 0.3607 | 0.4022 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 1 | 1 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0033 | 0.1857 | 1 |
Loa Loa (eye worm) | histone methyltransferase | 0.0008 | 0.0325 | 0.0238 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.1619 | 0.1518 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.3607 | 0.3582 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0182 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0052 | 0.3068 | 1 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0033 | 0.1857 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0142 | 0.8791 | 0.8776 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.1619 | 0.1587 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.022 | 0.0102 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.1619 | 0.1587 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.022 | 0.0102 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0027 | 0.152 | 0.1488 |
Echinococcus multilocularis | geminin | 0.0161 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.006 | 0.3607 | 0.353 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0182 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.3607 | 0.3582 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0033 | 0.1857 | 0.1759 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.3607 | 0.3582 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0033 | 0.1857 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.3607 | 0.3582 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0182 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0027 | 0.152 | 0.1617 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0033 | 0.1857 | 0.5893 |
Onchocerca volvulus | 0.0027 | 0.152 | 1 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.006 | 0.3607 | 0.4022 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0033 | 0.1857 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.022 | 0.0102 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0033 | 0.1857 | 0.1759 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0182 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0033 | 0.1857 | 0.5893 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0325 | 0.0209 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0182 | 1 |
Brugia malayi | TAR-binding protein | 0.006 | 0.3607 | 0.4022 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0182 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0033 | 0.1857 | 0.2005 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.1619 | 0.1518 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.022 | 0.0182 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0027 | 0.152 | 0.1617 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.3607 | 0.3582 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0033 | 0.1857 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0033 | 0.1857 | 0.5 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0008 | 0.0318 | 0.0231 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0058 | 0.346 | 0.3435 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.