Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0398 | 0.1384 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0071 | 0.2783 | 0.2783 |
Loa Loa (eye worm) | TAR-binding protein | 0.0071 | 0.2783 | 0.2783 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0398 | 0.1384 |
Brugia malayi | RNA binding protein | 0.0071 | 0.2783 | 0.2773 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0398 | 0.1384 |
Brugia malayi | Cytochrome P450 family protein | 0.0016 | 0.0318 | 0.0303 |
Echinococcus granulosus | tar DNA binding protein | 0.0071 | 0.2783 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0016 | 0.0318 | 0.5 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0016 | 0.0318 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0133 | 0.5594 | 0.5594 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0398 | 0.1384 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.2783 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0016 | 0.0318 | 0.0318 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0398 | 0.1384 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.2107 | 0.2107 |
Brugia malayi | TAR-binding protein | 0.0071 | 0.2783 | 0.2773 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0016 | 0.0318 | 0.0318 |
Brugia malayi | MH2 domain containing protein | 0.0133 | 0.5594 | 0.5587 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.2783 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0398 | 0.1384 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0133 | 0.5594 | 0.5594 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.2783 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.2783 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.2783 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0398 | 0.1384 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.1316 | 0.1303 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0071 | 0.2783 | 0.2773 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0398 | 0.0384 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0398 | 0.1384 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0016 | 0.0318 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.0015 | 0.0015 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.1316 | 0.4699 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0398 | 0.0398 |
Loa Loa (eye worm) | RNA binding protein | 0.0071 | 0.2783 | 0.2783 |
Brugia malayi | Cytochrome P450 family protein | 0.0016 | 0.0318 | 0.0303 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.0015 | 0.0015 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.2107 | 0.2095 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.2107 | 0.2107 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1316 | 0.1316 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0398 | 0.1384 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0398 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0398 | 0.0398 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0398 | 0.1384 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0016 | 0.0318 | 0.5 |
Leishmania major | cytochrome p450-like protein | 0.0016 | 0.0318 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.2107 | 0.2095 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0016 | 0.0318 | 0.0318 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0231 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0071 | 0.2783 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.