Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0143 | 0.5 |
Echinococcus multilocularis | muscleblind protein | 0.0152 | 0.2075 | 0.3376 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0143 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0046 | 0.052 | 0.0744 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0021 | 0.017 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.1083 | 0.0953 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0021 | 0.017 | 0.0042 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.004 | 0.0437 | 0.3124 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0207 | 0.0146 |
Brugia malayi | nuclear receptor RXR | 0.0024 | 0.0207 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.017 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.017 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0207 | 0.0065 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0143 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0046 | 0.052 | 0.0886 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.004 | 0.0437 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0046 | 0.052 | 0.0865 |
Echinococcus multilocularis | geminin | 0.0179 | 0.2457 | 0.4045 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0207 | 0.0146 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0021 | 0.017 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0697 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0151 | 0.0008 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0143 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0148 | 0.2009 | 0.3426 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0143 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0046 | 0.052 | 0.0865 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0046 | 0.052 | 0.0382 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0046 | 0.052 | 0.0658 |
Brugia malayi | conserved hypotetical protein | 0.0021 | 0.017 | 0.006 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0046 | 0.052 | 0.0886 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0207 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.017 | 0.0027 |
Brugia malayi | nuclear receptor RXR | 0.0021 | 0.017 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0207 | 0.0065 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0143 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0024 | 0.0207 | 0.0126 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0046 | 0.052 | 0.0658 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0046 | 0.052 | 0.0865 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0046 | 0.052 | 0.0382 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0143 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.017 | 0.0027 |
Onchocerca volvulus | 0.0021 | 0.017 | 0.0042 | |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0021 | 0.017 | 0.0046 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0046 | 0.052 | 0.0658 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0151 | 0.0258 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.0437 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0046 | 0.052 | 0.0382 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0257 | 0.3592 | 0.7925 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0021 | 0.017 | 0.0027 |
Brugia malayi | Muscle positioning protein 4 | 0.002 | 0.0151 | 0.0018 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.017 | 0.0052 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0084 | 0.1083 | 1 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0367 | 0.5201 | 0.8841 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.2457 | 0.4191 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0046 | 0.052 | 0.0658 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0024 | 0.0207 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.017 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.017 | 0.0027 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0021 | 0.017 | 0.0042 |
Loa Loa (eye worm) | acetyltransferase | 0.0148 | 0.2009 | 0.1893 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0046 | 0.052 | 0.0865 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.052 | 0.0382 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0046 | 0.052 | 0.0658 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0046 | 0.052 | 0.0744 |
Brugia malayi | nuclear receptor NHR-67 | 0.0021 | 0.017 | 0.006 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0021 | 0.017 | 0.006 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0143 | 1 |
Echinococcus granulosus | geminin | 0.0179 | 0.2457 | 0.4575 |
Brugia malayi | hypothetical protein | 0.0021 | 0.017 | 0.006 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0143 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0046 | 0.052 | 0.0744 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0143 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0413 | 0.5864 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.017 | 0.0027 |
Brugia malayi | ecdysone receptor | 0.0021 | 0.017 | 0.006 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0046 | 0.052 | 0.0382 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0021 | 0.017 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.052 | 0.0382 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0021 | 0.017 | 0.006 |
Schistosoma mansoni | nuclear receptor | 0.0021 | 0.017 | 0.0289 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0046 | 0.052 | 0.0886 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0046 | 0.052 | 0.0865 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.049 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0278 | 0.3905 | 0.8644 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0148 | 0.2009 | 0.4287 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0046 | 0.052 | 0.0848 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0143 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.049 | 0.5 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0021 | 0.017 | 0.0289 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2075 | 0.1959 |
Loa Loa (eye worm) | DOMON domain-containing protein | 0.002 | 0.0151 | 0.0008 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0021 | 0.017 | 0.0289 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2075 | 0.1959 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0046 | 0.052 | 0.0744 |
Brugia malayi | SEA domain containing protein | 0.002 | 0.0151 | 0.0018 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0046 | 0.052 | 0.0886 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.017 | 0.0027 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0143 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0046 | 0.052 | 0.0865 |
Schistosoma mansoni | hypothetical protein | 0.0367 | 0.5201 | 0.887 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0046 | 0.052 | 0.0848 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0143 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0257 | 0.3592 | 0.7925 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0021 | 0.017 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.017 | 0.0027 |
Brugia malayi | steroid hormone receptor | 0.0046 | 0.052 | 0.0865 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0207 | 0.0065 |
Brugia malayi | nuclear hormone receptor | 0.0046 | 0.052 | 0.0865 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0084 | 0.1083 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0143 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.0143 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0021 | 0.017 | 0.0289 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.017 | 0.0289 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.049 | 0.0685 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0046 | 0.052 | 0.0658 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0021 | 0.017 | 0.0046 |
Loa Loa (eye worm) | DR-78 | 0.0021 | 0.017 | 0.0027 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.049 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0151 | 0.0008 |
Brugia malayi | hypothetical protein | 0.0021 | 0.017 | 0.006 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0021 | 0.017 | 0.0046 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0021 | 0.017 | 0.006 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0046 | 0.052 | 0.0382 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.052 | 0.0382 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0024 | 0.0207 | 0.0353 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.017 | 0.0027 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0046 | 0.052 | 0.0382 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0046 | 0.052 | 0.0865 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0046 | 0.052 | 0.0658 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.017 | 0.0046 |
Echinococcus granulosus | FTZ F1 alpha | 0.0046 | 0.052 | 0.0744 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.017 | 0.006 |
Brugia malayi | tailless protein | 0.0021 | 0.017 | 0.006 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0046 | 0.052 | 0.0886 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0046 | 0.052 | 0.0886 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0143 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0046 | 0.052 | 0.0382 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.049 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.017 | 0.0289 |
Brugia malayi | ecdysteroid receptor | 0.0046 | 0.052 | 0.0865 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0046 | 0.052 | 0.0865 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0046 | 0.052 | 0.0865 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.052 | 0.0382 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0046 | 0.052 | 0.0865 |
Onchocerca volvulus | 0.0046 | 0.052 | 0.0848 | |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.052 | 0.0382 |
Brugia malayi | nuclear receptor NHR-88 | 0.0046 | 0.052 | 0.0865 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.052 | 0.0382 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0046 | 0.052 | 0.0886 |
Schistosoma mansoni | thyroid hormone receptor | 0.0413 | 0.5864 | 1 |
Onchocerca volvulus | 0.0319 | 0.4495 | 1 | |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0046 | 0.052 | 0.0744 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.0143 | 0.0245 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0144 | 0.1948 | 0.3569 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0021 | 0.017 | 0.0052 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0021 | 0.017 | 0.0052 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0021 | 0.017 | 0.0046 |
Brugia malayi | hypothetical protein | 0.0319 | 0.4495 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0046 | 0.052 | 0.0382 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0143 | 0.0245 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0021 | 0.017 | 0.006 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0143 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0152 | 0.2075 | 0.3376 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0148 | 0.2009 | 0.3261 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.017 | 0.006 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.0143 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0207 | 0.0065 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0046 | 0.052 | 0.0886 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0143 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0046 | 0.052 | 0.0744 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.017 | 0.0289 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0021 | 0.017 | 0.0289 |
Onchocerca volvulus | 0.0021 | 0.017 | 0.0042 | |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0143 | 0.0245 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0257 | 0.3592 | 0.3499 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.049 | 0.5 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0046 | 0.052 | 0.0865 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0024 | 0.0207 | 0.0353 |
Brugia malayi | Muscleblind-like protein | 0.0152 | 0.2075 | 0.4438 |
Loa Loa (eye worm) | hypothetical protein | 0.0319 | 0.4495 | 0.4415 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0046 | 0.052 | 0.0848 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0143 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0143 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0046 | 0.052 | 0.0865 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0046 | 0.052 | 0.0865 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.052 | 0.0382 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0367 | 0.5201 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0152 | 0.2075 | 0.3819 |
Schistosoma mansoni | nuclear hormone receptor | 0.0046 | 0.052 | 0.0886 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0021 | 0.017 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.017 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.052 | 0.0382 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0046 | 0.052 | 0.0886 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.0143 | 0.5 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0143 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0413 | 0.5864 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0046 | 0.052 | 0.0744 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0021 | 0.017 | 0.0046 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0046 | 0.052 | 0.0865 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0143 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.3555 | 0.3461 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0143 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.017 | 0.0027 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0143 | 0.5 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0021 | 0.017 | 0.006 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0046 | 0.052 | 0.0744 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0046 | 0.052 | 0.0886 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0046 | 0.052 | 0.0658 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0046 | 0.052 | 0.0865 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.2457 | 0.4191 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0021 | 0.017 | 0.0027 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0143 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 5.6 % | Activity of human recombinant acid ceramidase expressed in baculovirus infected Sf9 cells assessed as hydrolysis at 20 uM after 150 mins by TLC-based fluorescence imaging | ChEMBL. | 22989909 |
Activity (binding) | = 6.2 % | Activity of human recombinant neutral ceramidase assessed as hydrolysis at 20 uM after 60 mins by TLC-based fluorescence imaging | ChEMBL. | 22989909 |
Kcat (binding) | = 0.244 pmol/min | Activity of human recombinant acid ceramidase expressed in baculovirus infected Sf9 cells assessed per ug of protein after 150 mins by Lineweaver-Burk plot analysis | ChEMBL. | 22989909 |
Kcat (binding) | = 1.6 pmol/min | Activity of human recombinant neutral ceramidase assessed per ng of protein after 60 mins by Lineweaver-Burk plot analysis | ChEMBL. | 22989909 |
Km (binding) | = 192.9 uM | Activity of human recombinant neutral ceramidase after 60 mins by Lineweaver-Burk plot analysis | ChEMBL. | 22989909 |
Km (binding) | = 203.6 uM | Activity of human recombinant acid ceramidase expressed in baculovirus infected Sf9 cells after 150 mins by Lineweaver-Burk plot analysis | ChEMBL. | 22989909 |
Vmax (binding) | = 12.2 pmol/min | Activity of human recombinant acid ceramidase expressed in baculovirus infected Sf9 cells after 150 mins by Lineweaver-Burk plot analysis | ChEMBL. | 22989909 |
Vmax (binding) | = 31.8 pmol/min | Activity of human recombinant neutral ceramidase after 60 mins by Lineweaver-Burk plot analysis | ChEMBL. | 22989909 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.