Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0231 | 0.8137 | 1 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0231 | 0.8137 | 1 |
Echinococcus granulosus | proteasome prosome macropain | 0.0231 | 0.8137 | 1 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0231 | 0.8137 | 1 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0231 | 0.8137 | 1 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0069 | 0.16 | 0.1966 |
Onchocerca volvulus | 0.0277 | 1 | 0.5 | |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0231 | 0.8137 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.1351 | 0.1351 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0231 | 0.8137 | 1 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0069 | 0.16 | 0.1966 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0091 | 0.2517 | 0.2517 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0231 | 0.8137 | 1 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0231 | 0.8137 | 0.8137 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0069 | 0.16 | 0.1966 |
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.1351 | 0.166 |
Mycobacterium ulcerans | proteasome PrcB | 0.0231 | 0.8137 | 0.5 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0069 | 0.16 | 0.1966 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0231 | 0.8137 | 1 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0231 | 0.8137 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0091 | 0.2517 | 0.2517 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0231 | 0.8137 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0277 | 1 | 1 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0231 | 0.8137 | 1 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0069 | 0.16 | 0.16 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0091 | 0.2517 | 0.2517 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0069 | 0.16 | 0.1966 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0069 | 0.16 | 0.1966 |
Echinococcus multilocularis | geminin | 0.0158 | 0.5211 | 0.6404 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0231 | 0.8137 | 1 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0231 | 0.8137 | 1 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0069 | 0.16 | 0.1966 |
Schistosoma mansoni | hypothetical protein | 0.0158 | 0.5211 | 0.6404 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0069 | 0.16 | 0.1966 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.2517 | 0.2517 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0231 | 0.8137 | 0.8137 |
Echinococcus granulosus | geminin | 0.0158 | 0.5211 | 0.6404 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0062 | 0.1351 | 0.1351 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0231 | 0.8137 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0158 | 0.5211 | 0.6404 |
Brugia malayi | proteasome subunit beta type 1 | 0.0069 | 0.16 | 0.16 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0069 | 0.16 | 0.1966 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0069 | 0.16 | 0.1966 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.