TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 424.516 | Formula: C22H24N4O3S
H donors: 0 H acceptors: 3 LogP: 3.07 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: CC(=O)N1CC2C(C1)CN(C2)CCOc1ccc(cc1)Oc1nc2c(s1)cccn2
InChi: 1S/C22H24N4O3S/c1-15(27)26-13-16-11-25(12-17(16)14-26)9-10-28-18-4-6-19(7-5-18)29-22-24-21-20(30-22)3-2-8-23-21/h2-8,16-17H,9-14H2,1H3
InChiKey: IDNQVNKCKNBLIA-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	potassium voltage-gated channel, subfamily H (eag-related), member 2	Starlite/ChEMBL	References
Homo sapiens	leukotriene A4 hydrolase	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma mansoni	voltage-gated potassium channel	Get druggable targets OG5_128858	All targets in OG5_128858
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	Get druggable targets OG5_128858	All targets in OG5_128858
Candida albicans	leukotriene A4 hydrolase/leucyl aminopeptidase	Get druggable targets OG5_129538	All targets in OG5_129538
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_128858	All targets in OG5_128858
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	Get druggable targets OG5_128858	All targets in OG5_128858
Loa Loa (eye worm)	voltage and ligand gated potassium channel	Get druggable targets OG5_128858	All targets in OG5_128858
Schistosoma mansoni	leukotriene A4 hydrolase (M01 family)	Get druggable targets OG5_129538	All targets in OG5_129538
Schistosoma japonicum	ko:K04910 potassium voltage-gated channel, Eag-related subfamily H, member 7, putative	Get druggable targets OG5_128858	All targets in OG5_128858
Schistosoma mansoni	voltage-gated potassium channel	Get druggable targets OG5_128858	All targets in OG5_128858
Schistosoma japonicum	ko:K04910 potassium voltage-gated channel, Eag-related subfamily H, member 7, putative	Get druggable targets OG5_128858	All targets in OG5_128858
Candida albicans	leukotriene A4 hydrolase/leucyl aminopeptidase	Get druggable targets OG5_129538	All targets in OG5_129538
Loa Loa (eye worm)	leukotriene A4 hydrolase	Get druggable targets OG5_129538	All targets in OG5_129538
Echinococcus multilocularis	leukotriene A 4 hydrolase	Get druggable targets OG5_129538	All targets in OG5_129538
Echinococcus granulosus	potassium voltage gated channel subfamily H	Get druggable targets OG5_128858	All targets in OG5_128858
Echinococcus granulosus	leukotriene A 4 hydrolase	Get druggable targets OG5_129538	All targets in OG5_129538
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	Get druggable targets OG5_128858	All targets in OG5_128858
Schistosoma japonicum	ko:K01254 leukotriene-A4 hydrolase [EC3.3.2.6], putative	Get druggable targets OG5_129538	All targets in OG5_129538
Schistosoma japonicum	Potassium voltage-gated channel subfamily H member 2, putative	Get druggable targets OG5_128858	All targets in OG5_128858
Echinococcus multilocularis	potassium voltage gated channel subfamily H	Get druggable targets OG5_128858	All targets in OG5_128858

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Leishmania major	aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1	leukotriene A4 hydrolase	611 aa	508 aa	22.8 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0049	0.131	0.3051
Trypanosoma cruzi	puromycin-sensitive aminopeptidase-like protein, putative	0.0015	0	0.5
Plasmodium falciparum	M1-family alanyl aminopeptidase	0.0015	0	0.5
Trypanosoma cruzi	metallo-peptidase, clan MA(E), family M1, putative	0.0015	0	0.5
Trypanosoma brucei	aminopeptidase, putative	0.0015	0	0.5
Schistosoma mansoni	voltage-gated potassium channel	0.0049	0.1281	0.1281
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0049	0.131	0.3051
Loa Loa (eye worm)	leukotriene A4 hydrolase	0.0279	1	1
Brugia malayi	orphan nuclear receptor NR2E1	0.0023	0.0322	0.0749
Toxoplasma gondii	aminopeptidase N protein	0.0015	0	0.5
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0049	0.131	0.131
Trypanosoma cruzi	metallo-peptidase, clan MA(E), family M1, putative	0.0015	0	0.5
Entamoeba histolytica	aminopeptidase, putative	0.0015	0	0.5
Trypanosoma cruzi	Aminopeptidase M1, putative	0.0015	0	0.5
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0023	0.0322	0.0322
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0026	0.0428	0.0428
Echinococcus multilocularis	FTZ F1 alpha	0.0049	0.131	0.131
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0045	0.1126	0.1126
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0023	0.0322	0.2455
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0049	0.131	0.131
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0049	0.131	0.131
Schistosoma mansoni	thyroid hormone receptor	0.0049	0.131	0.131
Leishmania major	puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1	0.0015	0	0.5
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0049	0.131	0.131
Loa Loa (eye worm)	hypothetical protein	0.0049	0.131	0.131
Schistosoma mansoni	thyroid hormone receptor	0.0049	0.131	0.131
Schistosoma mansoni	nuclear hormone receptor	0.0023	0.0322	0.0322
Brugia malayi	hypothetical protein	0.0023	0.0322	0.0749
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Onchocerca volvulus		0.0023	0.0322	0.2455
Brugia malayi	tailless protein	0.0023	0.0322	0.0749
Echinococcus granulosus	FTZ F1 alpha	0.0049	0.131	0.131
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0045	0.1126	0.1126
Brugia malayi	ecdysteroid receptor	0.0049	0.131	0.3051
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0042	0.1015	1
Brugia malayi	hypothetical protein	0.0023	0.0322	0.0749
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0049	0.131	0.131
Plasmodium falciparum	M1-family alanyl aminopeptidase, putative	0.0015	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0428	0.0428
Echinococcus multilocularis	nuclear receptor nhr 48	0.0023	0.0322	0.0322
Brugia malayi	Nuclear hormone receptor-like 1	0.0026	0.0428	0.0996
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0049	0.131	0.131
Leishmania major	aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1	0.0015	0	0.5
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0023	0.0322	0.0322
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0049	0.131	0.131
Brugia malayi	Steroid receptor seven-up type 2	0.0049	0.131	0.3051
Leishmania major	aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1	0.0015	0	0.5
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0023	0.0322	0.0322
Brugia malayi	nuclear hormone receptor	0.0049	0.131	0.3051
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0049	0.131	0.131
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0049	0.131	0.131
Trypanosoma cruzi	aminopeptidase, putative	0.0015	0	0.5
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0049	0.131	0.3051
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0049	0.131	0.3051
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0049	0.131	0.3051
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0428	0.0428
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0049	0.131	0.131
Schistosoma mansoni	nuclear receptor	0.0023	0.0322	0.0322
Brugia malayi	nuclear hormone receptor	0.0023	0.0322	0.0749
Schistosoma mansoni	RAR-like nuclear receptor	0.0049	0.131	0.131
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.0023	0.0322	0.0322
Schistosoma mansoni	nuclear receptor	0.0023	0.0322	0.0322
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Brugia malayi	Nuclear hormone receptor E75	0.0023	0.0322	0.0749
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.0023	0.0322	0.0322
Onchocerca volvulus	Protein ultraspiracle homolog	0.0049	0.131	1
Echinococcus multilocularis	ecdysone induced protein 78C	0.0049	0.131	0.131
Brugia malayi	Nuclear hormone receptor-like 1	0.0049	0.131	0.3051
Brugia malayi	Nuclear hormone receptor E75	0.0023	0.0322	0.0749
Schistosoma mansoni	leukotriene A4 hydrolase (M01 family)	0.0279	1	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0049	0.131	0.3051
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.0023	0.0322	0.0749
Echinococcus granulosus	ecdysone induced protein 78C	0.0049	0.131	0.131
Trypanosoma cruzi	aminopeptidase, putative	0.0015	0	0.5
Trypanosoma cruzi	puromycin-sensitive aminopeptidase-like protein, putative	0.0015	0	0.5
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0049	0.131	0.131
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.0023	0.0322	0.0322
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0023	0.0322	0.2455
Plasmodium vivax	M1-family alanyl aminopeptidase, putative	0.0015	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Echinococcus granulosus	thyroid hormone receptor alpha	0.0023	0.0322	0.0322
Onchocerca volvulus		0.0023	0.0322	0.2455
Loa Loa (eye worm)	hypothetical protein	0.0049	0.131	0.131
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0049	0.131	0.3051
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0049	0.131	0.131
Brugia malayi	nuclear receptor RXR	0.0023	0.0322	0.0749
Brugia malayi	nuclear receptor NHR-67	0.0023	0.0322	0.0749
Brugia malayi	nuclear hormone receptor family member nhr-6	0.0023	0.0322	0.0749
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0049	0.131	0.131
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Trypanosoma cruzi	metallo-peptidase, Clan MA(E) Family M1	0.0015	0	0.5
Brugia malayi	nuclear receptor NHR-88	0.0049	0.131	0.3051
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0026	0.0428	0.0428
Loa Loa (eye worm)	hypothetical protein	0.0049	0.131	0.131
Mycobacterium ulcerans	aminopeptidase N PepN	0.0015	0	0.5
Loa Loa (eye worm)	DR-78	0.0023	0.0322	0.0322
Schistosoma mansoni	nuclear hormone receptor	0.0023	0.0322	0.0322
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0049	0.131	0.3051
Brugia malayi	ecdysone receptor	0.0023	0.0322	0.0749
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0023	0.0322	0.0322
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0049	0.131	0.131
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0042	0.1015	1
Onchocerca volvulus	Bile acid receptor homolog	0.0049	0.131	1
Schistosoma mansoni	nuclear hormone receptor	0.0049	0.131	0.131
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0049	0.131	0.3051
Schistosoma mansoni	voltage-gated potassium channel	0.0049	0.1281	0.1281
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0049	0.131	0.131
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0049	0.131	0.131
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0049	0.131	0.131
Trypanosoma brucei	metallo-peptidase, Clan MA(E) Family M1	0.0015	0	0.5
Loa Loa (eye worm)	steroid hormone receptor	0.0049	0.131	0.131
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.0023	0.0322	0.0322
Schistosoma mansoni	coup transcription factor	0.0049	0.131	0.131
Brugia malayi	nuclear receptor NHR-88	0.0023	0.0322	0.0749
Loa Loa (eye worm)	hypothetical protein	0.0049	0.131	0.131
Plasmodium vivax	M1-family alanyl aminopeptidase, putative	0.0015	0	0.5
Brugia malayi	nuclear receptor RXR	0.0026	0.0428	0.0996
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0023	0.0322	0.0322
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0049	0.131	0.131
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0049	0.131	0.3051
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0045	0.1126	0.2622
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0428	0.0428
Brugia malayi	steroid hormone receptor	0.0049	0.131	0.3051
Trypanosoma brucei	Aminopeptidase M1, putative	0.0015	0	0.5
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0049	0.131	0.3051
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0049	0.131	0.131
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0049	0.131	1
Leishmania major	aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1	0.0015	0	0.5
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0049	0.131	0.131
Brugia malayi	Nuclear hormone receptor-like 1	0.0026	0.0428	0.0996
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0023	0.0322	0.0322
Echinococcus multilocularis	leukotriene A 4 hydrolase	0.0279	1	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0049	0.131	0.131
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0049	0.131	0.131
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0026	0.0428	0.0428
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0045	0.1126	0.1126
Schistosoma mansoni	retinoic acid receptor RXR	0.0049	0.131	0.131
Brugia malayi	conserved hypotetical protein	0.0023	0.0322	0.0749
Echinococcus granulosus	nuclear receptor nhr 48	0.0023	0.0322	0.0322
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0049	0.131	0.131
Mycobacterium ulcerans	aminopeptidase N PepN	0.0015	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0049	0.131	0.131
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0428	0.0428
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Schistosoma mansoni	zinc finger protein	0.0023	0.0322	0.0322
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0049	0.131	0.131
Loa Loa (eye worm)	nuclear hormone receptor	0.0023	0.0322	0.0322
Loa Loa (eye worm)	nuclear receptor NHR-67	0.0023	0.0322	0.0322
Brugia malayi	nuclear hormone receptor family member odr-7	0.0023	0.0322	0.0749
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Toxoplasma gondii	aminopeptidase n, putative	0.0015	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Brugia malayi	hypothetical protein	0.0026	0.0428	0.0996
Toxoplasma gondii	aminopeptidase N, putative	0.0015	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0049	0.131	0.131
Trypanosoma brucei	Aminopeptidase M1, putative	0.0015	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0049	0.131	0.3051
Schistosoma mansoni	nuclear receptor nhr-48	0.0023	0.0322	0.0322
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.0023	0.0322	0.0322
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0322	0.0322
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0049	0.131	0.131
Brugia malayi	hypothetical protein	0.0026	0.0428	0.0996
Loa Loa (eye worm)	hypothetical protein	0.0049	0.131	0.131
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.0023	0.0322	0.0322
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0049	0.131	0.131
Loa Loa (eye worm)	hypothetical protein	0.0049	0.131	0.131
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0026	0.0428	0.0428
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0049	0.131	0.3051
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0049	0.131	0.131
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0026	0.0428	0.0428
Brugia malayi	photoreceptor-specific nuclear receptor	0.0049	0.131	0.3051
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0903	0.0903
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0428	0.0428
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0049	0.131	0.131
Brugia malayi	hypothetical protein	0.0128	0.4294	1
Onchocerca volvulus		0.0049	0.131	1

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 7 nM	Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior to substrate addition measured after 10 to 30 mins by enzyme immunoassay	ChEMBL.	23127888
IC50 (functional)	= 30 nM	Ex vivo inhibition of LTA4 hydrolase in po dosed Balb/c mouse whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production incubated for 4 hrs prior to calcium ionophore A23187 induction measured after 10 to 30 mins by enzyme immunoassay	ChEMBL.	23127888
IC50 (binding)	> 10 uM	Inhibition of dofetilide binding to human ERG by patch clamp assay	ChEMBL.	23127888
Inhibition (functional)	= 86 %	Ex vivo inhibition of MPO in arachidonic acid-induced ear inflammation Balb/c mouse model assessed as neutrophil influx at 30 mg/kg, po after 3 hrs	ChEMBL.	23127888

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Mus musculus	ChEMBL23	23127888

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2207739

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1686908