Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | Serotonin receptor | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.9606 | 0.9606 |
Brugia malayi | Dopamine receptor | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | Serotonin receptor | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | AKH receptor | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | G protein-coupled receptor | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | sulfakinin receptor protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | putative neuropeptide receptor | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | G-protein coupled receptor | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | RE15519p | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | larval opioid receptor | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | Dopamine receptor protein 1 | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Schistosoma mansoni | lamin | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Onchocerca volvulus | 0.0026 | 1 | 1 | |
Echinococcus multilocularis | lamin | 0.0026 | 1 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | Melatonin receptor type 1A | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | neuropeptide F receptor | 0.0019 | 0.4237 | 0.4237 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 1 | 1 |
Onchocerca volvulus | 0.0026 | 1 | 1 | |
Brugia malayi | Dopamine receptor protein 2 | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Schistosoma mansoni | lamin | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | neuropeptide F receptor | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | GnHR receptor homolog | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | ORL1-like opioid receptor | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0019 | 0.4237 | 0.4237 |
Brugia malayi | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Echinococcus multilocularis | musashi | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Echinococcus granulosus | lamin | 0.0026 | 1 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.4237 | 0.4237 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.