Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3241 | 0.3168 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0808 | 0.0824 |
Echinococcus multilocularis | geminin | 0.0165 | 1 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.145 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0162 | 0.9801 | 1 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0663 | 0.0676 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1313 | 0.134 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0808 | 0.0824 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.3241 | 0.3168 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.2352 | 0.24 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0808 | 0.0708 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.3241 | 0.3168 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0162 | 0.9801 | 0.9799 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0024 | 0.0663 | 0.0676 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.2352 | 0.24 |
Onchocerca volvulus | 0.0094 | 0.5276 | 1 | |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.3241 | 0.3307 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.145 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0107 | 0.0109 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.145 | 0.1357 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0808 | 0.0824 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3241 | 0.3168 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0808 | 0.0824 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.1313 | 0.134 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0107 | 0.0109 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0808 | 0.0708 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0107 | 0.0109 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.145 | 0.1479 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.145 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.145 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0162 | 0.9801 | 0.9799 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.3241 | 0.3307 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.145 | 1 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.145 | 0.1357 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3241 | 0.3168 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.2352 | 0.24 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0107 | 0.0109 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3241 | 0.3168 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.145 | 1 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0808 | 0.0824 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0663 | 0.0676 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0808 | 0.0708 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0024 | 0.0663 | 0.5 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0663 | 0.0562 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0024 | 0.0663 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.8306 | 0.8288 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3241 | 0.3168 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.145 | 1 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.3241 | 0.3307 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.3241 | 0.3307 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.8306 | 0.8288 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.145 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0162 | 0.9801 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.145 | 1 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0024 | 0.0663 | 0.0562 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.145 | 0.1357 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0024 | 0.0663 | 0.0562 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0808 | 0.0708 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.145 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.2352 | 0.24 |
Schistosoma mansoni | lamin | 0.0026 | 0.0808 | 0.0708 |
Schistosoma mansoni | lamin | 0.0026 | 0.0808 | 0.0708 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0808 | 0.0708 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0024 | 0.0663 | 0.5 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0162 | 0.9801 | 0.9799 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.145 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1313 | 0.1219 |
Echinococcus granulosus | lamin | 0.0026 | 0.0808 | 0.0708 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.145 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.145 | 0.1479 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0663 | 0.0562 |
Brugia malayi | RNA binding protein | 0.0063 | 0.3241 | 0.3307 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.3241 | 0.3307 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0776 | 0.0792 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0808 | 0.0708 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.145 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.145 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.145 | 1 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0663 | 0.0562 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.145 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.