Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0059 | 0.0181 |
Schistosoma mansoni | lipoxygenase | 0.0053 | 0.0231 | 0.0758 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0018 | 0.0016 |
Brugia malayi | glutathione reductase | 0.0083 | 0.042 | 0.1454 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0077 | 0.0382 | 0.0369 |
Brugia malayi | Pre-SET motif family protein | 0.0204 | 0.1182 | 0.4094 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0129 | 0.0711 | 0.2464 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0473 | 0.2888 | 0.2878 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0059 | 0.0205 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0185 | 0.1062 | 0.778 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.008 | 0.0398 | 0.0518 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0084 | 0.0423 | 0.041 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0084 | 0.0423 | 0.1425 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0059 | 0.0437 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.008 | 0.0398 | 0.0518 |
Schistosoma mansoni | tyrosine kinase | 0.017 | 0.0966 | 0.3316 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0029 | 0.0075 | 0.0215 |
Mycobacterium ulcerans | lipase LipD | 0.0185 | 0.1062 | 1 |
Treponema pallidum | NADH oxidase | 0.0029 | 0.0075 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0083 | 0.042 | 0.1414 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0189 | 0.1088 | 0.374 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0059 | 0.0181 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0075 | 0.0252 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0378 | 0.2286 | 0.7916 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.007 | 0.0199 |
Plasmodium falciparum | thioredoxin reductase | 0.0029 | 0.0075 | 0.152 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.2286 | 0.7907 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.008 | 0.0398 | 0.2834 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0077 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1062 | 0.365 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0029 | 0.0075 | 0.0252 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.008 | 0.0398 | 0.2834 |
Schistosoma mansoni | tyrosine kinase | 0.0171 | 0.0978 | 0.3356 |
Brugia malayi | Doublecortin family protein | 0.0019 | 0.0013 | 0.0046 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0185 | 0.1062 | 0.365 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0059 | 0.0159 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.0962 | 0.33 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1062 | 0.365 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0185 | 0.1062 | 1 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0018 | 0.0016 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0059 | 0.0181 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0185 | 0.1062 | 0.4605 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1062 | 0.365 |
Schistosoma mansoni | tyrosine kinase | 0.017 | 0.0966 | 0.3316 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.008 | 0.0398 | 0.134 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.008 | 0.0398 | 0.0386 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.019 | 0.1096 | 0.1466 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0053 | 0.0231 | 0.0218 |
Echinococcus granulosus | tar DNA binding protein | 0.0129 | 0.0711 | 0.2429 |
Schistosoma mansoni | acetylcholinesterase | 0.008 | 0.0398 | 0.134 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0473 | 0.2888 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0185 | 0.1062 | 0.1421 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.008 | 0.0398 | 0.0386 |
Plasmodium vivax | hypothetical protein, conserved | 0.0185 | 0.1062 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0185 | 0.1062 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.019 | 0.1096 | 0.1466 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0029 | 0.0075 | 0.0425 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0211 | 0.123 | 0.1649 |
Loa Loa (eye worm) | RNA binding protein | 0.0129 | 0.0711 | 0.2429 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0077 | 0.0268 |
Echinococcus multilocularis | 0.0099 | 0.0518 | 0.0505 | |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0398 | 0.134 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0018 | 0.0045 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.008 | 0.0398 | 0.134 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0083 | 0.042 | 0.1772 |
Onchocerca volvulus | 0.0232 | 0.136 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0398 | 0.134 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0711 | 0.2429 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.0962 | 0.33 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0029 | 0.0075 | 0.0252 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0185 | 0.1062 | 0.1421 |
Brugia malayi | Carboxylesterase family protein | 0.008 | 0.0398 | 0.138 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0102 | 0.0538 | 0.1825 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0319 | 0.1913 | 0.6609 |
Echinococcus granulosus | carboxylesterase 5A | 0.0473 | 0.2888 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0029 | 0.0075 | 0.0589 |
Echinococcus multilocularis | acetylcholinesterase | 0.0473 | 0.2888 | 0.2878 |
Schistosoma mansoni | gabp alpha | 0.0077 | 0.0382 | 0.1281 |
Brugia malayi | Ets-domain containing protein | 0.0077 | 0.0382 | 0.1321 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0077 | 0.0568 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0185 | 0.1062 | 0.365 |
Brugia malayi | beta-lactamase | 0.0185 | 0.1062 | 0.3679 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0185 | 0.1062 | 0.1421 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0029 | 0.0075 | 0.026 |
Schistosoma mansoni | tyrosine kinase | 0.0171 | 0.0978 | 0.3356 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.008 | 0.0398 | 0.134 |
Toxoplasma gondii | thioredoxin reductase | 0.0083 | 0.042 | 0.3847 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0075 | 0.0252 |
Loa Loa (eye worm) | carboxylesterase | 0.0473 | 0.2888 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0077 | 0.0223 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0029 | 0.0075 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0029 | 0.0075 | 1 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0319 | 0.1913 | 0.6625 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.019 | 0.1096 | 0.1466 |
Mycobacterium tuberculosis | Conserved protein | 0.0185 | 0.1062 | 0.1421 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0075 | 0.0252 |
Brugia malayi | Protein kinase domain containing protein | 0.0102 | 0.0538 | 0.1863 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0319 | 0.1913 | 0.1902 |
Loa Loa (eye worm) | carboxylesterase | 0.008 | 0.0398 | 0.134 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 0.136 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0275 | 0.246 |
Mycobacterium ulcerans | beta-lactamase | 0.0185 | 0.1062 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.008 | 0.0398 | 0.134 |
Schistosoma mansoni | tyrosine kinase | 0.017 | 0.0966 | 0.3316 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0029 | 0.0075 | 0.152 |
Brugia malayi | Carboxylesterase family protein | 0.0473 | 0.2888 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.019 | 0.1096 | 0.1986 |
Brugia malayi | RNA binding protein | 0.0129 | 0.0711 | 0.2464 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0189 | 0.1088 | 0.374 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0077 | 0.0064 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0378 | 0.2286 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0185 | 0.1062 | 0.1421 |
Loa Loa (eye worm) | TAR-binding protein | 0.0129 | 0.0711 | 0.2429 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0021 | 0.0027 | 0.0092 |
Echinococcus granulosus | acetylcholinesterase | 0.0473 | 0.2888 | 1 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.0018 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0473 | 0.2888 | 0.2878 |
Echinococcus granulosus | acetylcholinesterase | 0.0473 | 0.2888 | 1 |
Brugia malayi | Fli-1 protein | 0.0234 | 0.1378 | 0.4771 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0185 | 0.1062 | 0.4605 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0473 | 0.2888 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0185 | 0.1062 | 1 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0029 | 0.0075 | 0.0078 |
Onchocerca volvulus | 0.0151 | 0.0846 | 0.6183 | |
Loa Loa (eye worm) | fli-1 protein | 0.0234 | 0.1378 | 0.4747 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1062 | 0.365 |
Mycobacterium tuberculosis | Conserved protein | 0.0185 | 0.1062 | 0.1421 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0029 | 0.0075 | 0.0252 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0189 | 0.1088 | 0.374 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0077 | 0.0382 | 0.1281 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0018 | 0.0062 |
Loa Loa (eye worm) | beta-lactamase | 0.0185 | 0.1062 | 0.365 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.019 | 0.1096 | 0.1466 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0029 | 0.0075 | 0.0215 |
Mycobacterium tuberculosis | Probable reductase | 0.019 | 0.1096 | 0.1466 |
Brugia malayi | hypothetical protein | 0.008 | 0.0398 | 0.138 |
Brugia malayi | Carboxylesterase family protein | 0.008 | 0.0398 | 0.138 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0185 | 0.1062 | 0.3679 |
Loa Loa (eye worm) | hypothetical protein | 0.0473 | 0.2888 | 1 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0029 | 0.0075 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0275 | 0.246 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0207 | 0.0674 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0053 | 0.0231 | 0.0758 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0018 | 0.0116 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.008 | 0.0398 | 0.134 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0018 | 0.0016 |
Onchocerca volvulus | 0.008 | 0.0398 | 0.2859 | |
Echinococcus granulosus | BC026374 protein S09 family | 0.008 | 0.0398 | 0.134 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0275 | 0.091 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0107 | 0.0327 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0711 | 0.2429 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0398 | 0.134 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0211 | 0.123 | 0.1649 |
Brugia malayi | hypothetical protein | 0.0151 | 0.0846 | 0.293 |
Brugia malayi | beta-lactamase family protein | 0.0185 | 0.1062 | 0.3679 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0207 | 0.0717 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0013 | 0.0046 |
Onchocerca volvulus | 0.0185 | 0.1062 | 0.7787 | |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0077 | 0.061 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0275 | 0.246 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0189 | 0.1088 | 0.1076 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0185 | 0.1062 | 0.105 |
Onchocerca volvulus | 0.008 | 0.0398 | 0.2859 | |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0185 | 0.1062 | 0.1421 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.118 | 0.7367 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0185 | 0.1062 | 0.3679 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.008 | 0.0398 | 0.134 |
Schistosoma mansoni | tyrosine kinase | 0.0102 | 0.0538 | 0.1825 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0204 | 0.1182 | 0.4067 |
Loa Loa (eye worm) | glutathione reductase | 0.0083 | 0.042 | 0.1414 |
Echinococcus multilocularis | insulin receptor | 0.0102 | 0.0538 | 0.0525 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0029 | 0.0075 | 0.0252 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0189 | 0.1088 | 0.3768 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0171 | 0.0978 | 0.0966 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0107 | 0.0372 |
Plasmodium vivax | glutathione reductase, putative | 0.0083 | 0.042 | 0.3875 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.008 | 0.0398 | 0.3643 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1062 | 0.365 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0029 | 0.0075 | 0.0547 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0846 | 0.2898 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0077 | 0.0223 |
Echinococcus granulosus | neuroligin | 0.008 | 0.0398 | 0.134 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0275 | 0.035 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0059 | 0.1128 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0077 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0398 | 0.134 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0185 | 0.1062 | 0.365 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0171 | 0.0978 | 0.3356 |
Onchocerca volvulus | 0.0185 | 0.1062 | 0.7787 | |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0029 | 0.0075 | 0.0252 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0238 | 0.1402 | 0.483 |
Echinococcus granulosus | insulin receptor | 0.0102 | 0.0538 | 0.1825 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0029 | 0.0075 | 0.0547 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0018 | 0.0016 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0171 | 0.0978 | 0.3356 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.019 | 0.1096 | 0.1466 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0013 | 0.0046 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0189 | 0.1088 | 0.374 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0185 | 0.1062 | 0.778 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0185 | 0.1062 | 0.1421 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0311 | 0.1034 |
Brugia malayi | follicle stimulating hormone receptor | 0.0238 | 0.1402 | 0.4854 |
Onchocerca volvulus | 0.0029 | 0.0077 | 0.0475 | |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0275 | 0.091 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0029 | 0.0075 | 0.0252 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0021 | 0.0027 | 0.0092 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.008 | 0.0398 | 0.134 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0378 | 0.2286 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0185 | 0.1062 | 0.778 |
Schistosoma mansoni | tyrosine kinase | 0.0102 | 0.0538 | 0.1825 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0129 | 0.0711 | 0.2429 |
Brugia malayi | Ets-domain containing protein | 0.0077 | 0.0382 | 0.1321 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0102 | 0.0538 | 0.1825 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0185 | 0.1062 | 0.4605 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0189 | 0.1088 | 0.374 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0029 | 0.0075 | 0.0547 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.008 | 0.0398 | 0.0518 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0211 | 0.123 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0029 | 0.0075 | 0.152 |
Trypanosoma brucei | trypanothione reductase | 0.0083 | 0.042 | 0.1772 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0075 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0107 | 0.0327 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0319 | 0.1913 | 0.6609 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0083 | 0.042 | 0.3875 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0077 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1062 | 0.365 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0029 | 0.0075 | 0.0252 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0077 | 0.0382 | 0.1281 |
Brugia malayi | TAR-binding protein | 0.0129 | 0.0711 | 0.2464 |
Echinococcus multilocularis | geminin | 0.0169 | 0.0962 | 0.095 |
Brugia malayi | Carboxylesterase family protein | 0.0473 | 0.2888 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0473 | 0.2888 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0077 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0398 | 0.134 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.008 | 0.0398 | 0.0386 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0075 | 0.0252 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0029 | 0.0075 | 0.0252 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0018 | 0.0005 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0185 | 0.1062 | 0.778 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0185 | 0.1062 | 0.365 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0029 | 0.0075 | 0.0589 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0207 | 0.0674 |
Schistosoma mansoni | tyrosine kinase | 0.0319 | 0.1913 | 0.6609 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0075 | 0.0252 |
Leishmania major | hypothetical protein, conserved | 0.0185 | 0.1062 | 0.4605 |
Echinococcus granulosus | geminin | 0.0169 | 0.0962 | 0.33 |
Leishmania major | trypanothione reductase | 0.0083 | 0.042 | 0.1772 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0029 | 0.0075 | 0.0252 |
Plasmodium falciparum | glutathione reductase | 0.0083 | 0.042 | 1 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0029 | 0.0075 | 0.0547 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0275 | 0.246 |
Echinococcus multilocularis | tar DNA binding protein | 0.0129 | 0.0711 | 0.0699 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0059 | 0.1128 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0711 | 0.2429 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0275 | 0.1133 |
Onchocerca volvulus | 0.008 | 0.0398 | 0.2859 | |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0275 | 0.0262 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0207 | 0.0717 |
Schistosoma mansoni | gliotactin | 0.008 | 0.0398 | 0.134 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0275 | 0.091 |
Plasmodium falciparum | glutathione reductase | 0.0029 | 0.0075 | 0.152 |
Toxoplasma gondii | ABC1 family protein | 0.0185 | 0.1062 | 1 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0029 | 0.0075 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0059 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.1116 | 0.3835 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0059 | 0.0181 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0189 | 0.1088 | 0.1076 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0398 | 0.134 |
Brugia malayi | Thioredoxin reductase | 0.0083 | 0.042 | 0.1454 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0075 | 0.0252 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0029 | 0.0075 | 0.0547 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0711 | 0.2429 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0711 | 0.2429 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0083 | 0.042 | 0.0547 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0211 | 0.123 | 0.1649 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0185 | 0.1062 | 0.778 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0378 | 0.2286 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0185 | 0.1062 | 0.778 |
Onchocerca volvulus | 0.0185 | 0.1062 | 0.7787 | |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0398 | 0.134 |
Onchocerca volvulus | 0.008 | 0.0398 | 0.2859 | |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0185 | 0.1062 | 0.1421 |
Echinococcus multilocularis | neuroligin | 0.008 | 0.0398 | 0.0386 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0077 | 0.0223 |
Brugia malayi | Carboxylesterase family protein | 0.008 | 0.0398 | 0.138 |
Schistosoma mansoni | ets-related | 0.0234 | 0.1378 | 0.4747 |
Plasmodium falciparum | thioredoxin reductase | 0.0083 | 0.042 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0185 | 0.1062 | 0.1421 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0102 | 0.0538 | 0.0525 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0029 | 0.0075 | 0.0062 |
Brugia malayi | Carboxylesterase family protein | 0.008 | 0.0398 | 0.138 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0075 | 0.0252 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0029 | 0.0075 | 0.0425 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0189 | 0.1088 | 0.374 |
Onchocerca volvulus | 0.008 | 0.0398 | 0.2859 | |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.008 | 0.0398 | 0.134 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.