Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3612 | 0.4346 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0126 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.8311 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0111 | 0.8311 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.8311 | 0.5 |
Brugia malayi | RNA binding protein | 0.0067 | 0.3612 | 0.3612 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.4189 | 0.504 |
Schistosoma mansoni | hypothetical protein | 0.0111 | 0.8311 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0111 | 0.8311 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0067 | 0.3612 | 0.3612 |
Brugia malayi | TAR-binding protein | 0.0067 | 0.3612 | 0.3612 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3612 | 0.4346 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0072 | 0.4189 | 0.4189 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0067 | 0.3612 | 0.3612 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0106 | 0.7798 | 0.7798 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.7798 | 0.7798 |
Echinococcus multilocularis | tar DNA binding protein | 0.0067 | 0.3612 | 0.4346 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.8311 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0126 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3612 | 0.4346 |
Brugia malayi | hypothetical protein | 0.0111 | 0.8311 | 0.8311 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3612 | 0.4346 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0106 | 0.7798 | 0.7798 |
Entamoeba histolytica | hypothetical protein | 0.0111 | 0.8311 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.4189 | 0.4189 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0067 | 0.3612 | 0.3612 |
Loa Loa (eye worm) | TAR-binding protein | 0.0067 | 0.3612 | 0.3612 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0111 | 0.8311 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.3612 | 0.4346 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0106 | 0.7798 | 0.7798 |
Echinococcus granulosus | tar DNA binding protein | 0.0067 | 0.3612 | 0.4346 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.