Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | TAR-binding protein | 0.0136 | 0.616 | 0.606 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0036 | 0.0725 | 0.0619 |
Onchocerca volvulus | Alhambra homolog | 0.0034 | 0.0619 | 0.5 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0034 | 0.0619 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0043 | 0.1119 | 0.0888 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0725 | 0.0725 |
Echinococcus granulosus | GPCR family 2 | 0.0036 | 0.0725 | 0.0619 |
Loa Loa (eye worm) | TAR-binding protein | 0.0136 | 0.616 | 0.616 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0077 | 0.2979 | 0.2797 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0043 | 0.1119 | 0.1119 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0906 | 0.067 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0113 | 0.4922 | 0.4791 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.0903 | 0.08 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.0903 | 0.08 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0113 | 0.4922 | 0.4791 |
Schistosoma mansoni | bromodomain containing protein | 0.0069 | 0.2518 | 0.2518 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0034 | 0.0619 | 0.0619 |
Schistosoma mansoni | tar DNA-binding protein | 0.0136 | 0.616 | 0.616 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0906 | 0.0802 |
Schistosoma mansoni | tar DNA-binding protein | 0.0136 | 0.616 | 0.616 |
Brugia malayi | Bromodomain containing protein | 0.0081 | 0.321 | 0.3034 |
Brugia malayi | jmjC domain containing protein | 0.0111 | 0.48 | 0.4665 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0619 | 0.0619 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0043 | 0.1119 | 0.1017 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0065 | 0.2307 | 0.2219 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0036 | 0.0725 | 0.0619 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.1119 | 0.1119 |
Echinococcus multilocularis | tar DNA binding protein | 0.0136 | 0.616 | 0.6116 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0065 | 0.2307 | 0.2219 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.1119 | 0.1119 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0725 | 0.0725 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0206 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0906 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1047 | 0.1047 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0906 | 0.5 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0047 | 0.1339 | 0.124 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0206 | 1 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0113 | 0.0113 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0041 | 0.1006 | 0.0903 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.2958 | 0.2958 |
Echinococcus granulosus | peregrin | 0.0036 | 0.0759 | 0.0653 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.4922 | 0.4922 |
Schistosoma mansoni | tar DNA-binding protein | 0.0136 | 0.616 | 0.616 |
Echinococcus multilocularis | geminin | 0.0175 | 0.8324 | 0.8305 |
Schistosoma mansoni | tar DNA-binding protein | 0.0136 | 0.616 | 0.616 |
Echinococcus multilocularis | GPCR, family 2 | 0.0036 | 0.0725 | 0.0619 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0036 | 0.0725 | 0.0484 |
Echinococcus granulosus | jumonji domain containing protein | 0.0047 | 0.1339 | 0.124 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0906 | 0.0906 |
Schistosoma mansoni | jumonji domain containing protein | 0.0088 | 0.3563 | 0.3563 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0034 | 0.0619 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1932 | 0.1932 |
Brugia malayi | PHD-finger family protein | 0.0034 | 0.0619 | 0.0376 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0113 | 0.4922 | 0.4922 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0206 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0175 | 0.8324 | 0.8305 |
Schistosoma mansoni | tar DNA-binding protein | 0.0136 | 0.616 | 0.616 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0906 | 0.0802 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0036 | 0.0725 | 0.0619 |
Loa Loa (eye worm) | RNA binding protein | 0.0136 | 0.616 | 0.616 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0136 | 0.616 | 0.616 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0906 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.2979 | 0.2979 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.13 | 0.13 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.007 | 0.2576 | 0.2576 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0136 | 0.616 | 0.606 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0206 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0725 | 0.0725 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0036 | 0.0725 | 0.0484 |
Echinococcus granulosus | tar DNA binding protein | 0.0136 | 0.616 | 0.6116 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0111 | 0.48 | 0.474 |
Echinococcus multilocularis | peregrin | 0.0036 | 0.0759 | 0.0653 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0034 | 0.0619 | 0.0512 |
Plasmodium vivax | hypothetical protein, conserved | 0.0034 | 0.0619 | 0.5 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0034 | 0.0619 | 0.0619 |
Brugia malayi | Bromodomain containing protein | 0.0036 | 0.0759 | 0.0519 |
Brugia malayi | RNA binding protein | 0.0136 | 0.616 | 0.606 |
Schistosoma mansoni | hypothetical protein | 0.0077 | 0.2979 | 0.2979 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0725 | 0.0725 |
Giardia lamblia | PHD finger protein 15 | 0.0034 | 0.0619 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0906 | 0.0906 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.8324 | 0.8324 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0206 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0206 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0206 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0206 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0725 | 0.0725 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0034 | 0.0619 | 0.0512 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0111 | 0.48 | 0.474 |
Plasmodium falciparum | phd finger protein, putative | 0.0034 | 0.0619 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0906 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0042 | 0.1043 | 0.0811 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.1187 | 0.1187 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.8324 | 0.8324 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0036 | 0.0725 | 0.0725 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0036 | 0.0725 | 0.0619 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0619 | 0.0619 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.