Detailed information for compound 1693524

Basic information

Technical information
  • TDR Targets ID: 1693524
  • Name: (4S,6R)-6-[(E)-2-[4-(4-fluorophenyl)-6-phenyl -2-propan-2-ylpyridin-3-yl]ethenyl]-4-hydroxy oxan-2-one
  • MW: 431.499 | Formula: C27H26FNO3
  • H donors: 1 H acceptors: 3 LogP: 5.22 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@@H]1CC(=O)O[C@H](C1)/C=C/c1c(nc(cc1c1ccc(cc1)F)c1ccccc1)C(C)C
  • InChi: 1S/C27H26FNO3/c1-17(2)27-23(13-12-22-14-21(30)15-26(31)32-22)24(18-8-10-20(28)11-9-18)16-25(29-27)19-6-4-3-5-7-19/h3-13,16-17,21-22,30H,14-15H2,1-2H3/b13-12+/t21-,22-/m0/s1
  • InChiKey: LJIZUXQINHXGAO-WYCPQIHASA-N  


Substructure search Similarity search

Network

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Synonyms

  • (4S,6R)-6-[(E)-2-[4-(4-fluorophenyl)-2-isopropyl-6-phenyl-3-pyridyl]vinyl]-4-hydroxy-tetrahydropyran-2-one
  • (4S,6R)-6-[(E)-2-[4-(4-fluorophenyl)-2-isopropyl-6-phenyl-3-pyridyl]vinyl]-4-hydroxy-2-tetrahydropyranone
  • (4S,6R)-6-[(E)-2-[4-(4-fluorophenyl)-6-phenyl-2-propan-2-yl-pyridin-3-yl]ethenyl]-4-hydroxy-oxan-2-one

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0034 0.0031
Echinococcus granulosus hyperpolarization activated cyclic 0.0084 0.0289 0.0286
Echinococcus granulosus intermediate filament protein 0.0194 0.0817 0.0815
Brugia malayi RNA, U transporter 1 0.025 0.1087 0.1078
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0232 0.0229
Loa Loa (eye worm) hypothetical protein 0.0072 0.0233 0.0223
Toxoplasma gondii transporter, cation channel family protein 0.0084 0.0289 0.176
Loa Loa (eye worm) hypothetical protein 0.0082 0.0277 0.0267
Mycobacterium tuberculosis Conserved protein 0.0072 0.0233 0.1105
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0083 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0043 0.0131
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0147 0.0897
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0365 0.1641 0.1638
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0151 0.0613 0.0611
Loa Loa (eye worm) hypothetical protein 0.0052 0.0134 0.0124
Leishmania major cathepsin L-like protease 0.0066 0.0201 0.0668
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0083 0.0127
Loa Loa (eye worm) glutathione reductase 0.0047 0.0111 0.0101
Brugia malayi polk-prov protein 0.0042 0.0089 0.0079
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0003
Echinococcus multilocularis short transient receptor potential channel 6 0.0084 0.0289 0.0287
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.002 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0197 0.0832 0.0829
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0029
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0057 0.008
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0084 0.0289 0.0286
Onchocerca volvulus 0.0027 0.0013 0.0005
Brugia malayi Calcitonin receptor-like protein seb-1 0.0258 0.1124 0.1115
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0026 0.001 0.0007
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0059 0.0165
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0155 0.063 0.353
Brugia malayi Latrophilin receptor protein 2 0.0082 0.0277 0.0267
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0034 0.0207
Schistosoma mansoni hypothetical protein 0.0082 0.0277 0.0275
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0258 0.1124 0.1115
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0151 0.0613 0.3738
Brugia malayi Pre-SET motif family protein 0.1041 0.4887 0.4882
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.033 0.1474 0.5195
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0233 0.0396
Leishmania major hypothetical protein, unknown function 0.0084 0.0289 0.0982
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0191 0.0802 0.0799
Echinococcus granulosus transient receptor potential cation channel 0.0084 0.0289 0.0286
Brugia malayi hypothetical protein 0.0356 0.1594 0.1586
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0084 0.0289 0.0286
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.004 0.0079 0.0077
Echinococcus granulosus importin subunit beta 1 0.0088 0.0308 0.0305
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.021 0.0722
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0289 0.1277 0.4507
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0059 0.0165
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0002
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0111 0.0678
Mycobacterium ulcerans putative regulatory protein 0.0075 0.0248 0.1512
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0077 0.0256 0.0865
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0075 0.0248 0.1077
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.001 0.0062
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Leishmania major mitochondrial DNA polymerase beta 0.0612 0.2825 1
Echinococcus granulosus acetylcholinesterase 0.2104 1 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0289 0.1277 0.4494
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0185 0.0776 0.3687
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0233 0.0223
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0084 0.0289 0.0982
Brugia malayi Nuclear hormone receptor E75 0.0191 0.0802 0.0793
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0041 0.0083 0.0395
Onchocerca volvulus 0.0028 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0197 0.0832 0.0822
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0075 0.0248 0.1509
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0083 0.008
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0026 0.001 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0029
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0458 0.5837
Echinococcus granulosus short transient receptor potential channel 6 0.0084 0.0289 0.0286
Brugia malayi Cyclic-nucleotide gated cation channel 0.0084 0.0289 0.0279
Loa Loa (eye worm) abnormal epIthelia family member 0.0052 0.0134 0.0124
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Brugia malayi Intermediate filament tail domain containing protein 0.0194 0.0817 0.0808
Schistosoma mansoni importin beta-1 0.0088 0.0308 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0083 0.0127
Schistosoma mansoni memapsin-2 (A01 family) 0.0423 0.192 0.1917
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0185 0.0776 0.3687
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0057 0.0054
Echinococcus granulosus potassium voltage gated channel protein 0.0084 0.0289 0.0286
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0269 0.118 0.1171
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0612 0.2825 1
Trichomonas vaginalis ap endonuclease, putative 0.0075 0.0248 0.0422
Schistosoma mansoni nuclear hormone receptor 0.0414 0.1874 0.1871
Mycobacterium ulcerans beta-lactamase 0.0072 0.0233 0.1418
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.004 0.0079 0.0484
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0059 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.021 0.0722
Mycobacterium leprae Probable lipase LipE 0.0072 0.0233 0.2882
Brugia malayi RNA binding protein 0.0194 0.0818 0.0809
Brugia malayi laminin-like protein K08C7.3 precursor 0.0052 0.0134 0.0124
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0052 0.0134 0.0131
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0233 0.1105
Echinococcus granulosus Niemann Pick C1 protein 0.058 0.2672 0.267
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.001 0.0062
Onchocerca volvulus 0.0041 0.0081 0.0128
Schistosoma mansoni gliotactin 0.0356 0.1594 0.1592
Loa Loa (eye worm) acetylcholinesterase 1 0.2104 1 1
Toxoplasma gondii HEAT repeat-containing protein 0.0088 0.0308 0.1876
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0084 0.0289 0.0286
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0014 0.0002
Echinococcus multilocularis cpg binding protein 0.0125 0.0486 0.0483
Brugia malayi orphan nuclear receptor NR2E1 0.0191 0.0802 0.0793
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.001 0.0007
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0153 0.0621 0.0618
Brugia malayi regulator of G-protein signaling egl-10 0.0041 0.0083 0.0073
Onchocerca volvulus 0.0356 0.1594 0.2846
Brugia malayi conserved hypotetical protein 0.0191 0.0802 0.0793
Trypanosoma brucei DNA polymerase eta, putative 0.0062 0.0184 0.0631
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.001
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0065 0.0196 0.0675
Brugia malayi A-kinase anchor protein 10, precursor 0.0041 0.0083 0.0073
Loa Loa (eye worm) steroid hormone receptor 0.0414 0.1874 0.1865
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0026 0.001 0.0007
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0365 0.1641 0.2926
Loa Loa (eye worm) serotonin transporter b 0.0153 0.0621 0.0611
Loa Loa (eye worm) hypothetical protein 0.0052 0.0134 0.0124
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0034 0.0031
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0065 0.0196 0.0194
Mycobacterium ulcerans hypothetical protein 0.0072 0.0233 0.1418
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0072 0.0233 0.0223
Schistosoma mansoni slit 0.0052 0.0134 0.0131
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0401 0.1904
Brugia malayi PXA domain containing protein 0.0041 0.0083 0.0073
Brugia malayi Thioredoxin reductase 0.0047 0.0111 0.0101
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0691
Echinococcus granulosus dna polymerase eta 0.0062 0.0184 0.0181
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0185 0.0776 0.4731
Schistosoma mansoni cpg binding protein 0.0125 0.0486 0.0483
Toxoplasma gondii transporter, major facilitator family protein 0.0028 0.002 0.0123
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0083 0.008
Echinococcus granulosus GTP binding nuclear protein Ran 0.0065 0.0196 0.0194
Mycobacterium tuberculosis Conserved protein 0.0072 0.0233 0.1105
Schistosoma mansoni patched 1 0.0269 0.118 0.1177
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0414 0.1874 0.1865
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.004 0.0079 0.0069
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0083 0.008
Plasmodium falciparum amino acid transporter, putative 0.0026 0.001 0.0062
Treponema pallidum exodeoxyribonuclease (exoA) 0.0075 0.0248 0.1509
Brugia malayi cation channel family protein 0.0084 0.0289 0.0279
Giardia lamblia DNA topoisomerase II 0.0069 0.0219 0.0892
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.033 0.1474 0.1471
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0121 0.0467 0.1615
Echinococcus granulosus activated cdc42 kinase 1 0.035 0.1567 0.1565
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0156 0.0634 0.1117
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0065 0.0196 0.1196
Schistosoma mansoni DNA topoisomerase II 0.0073 0.0234 0.0231
Entamoeba histolytica Ran family GTPase 0.0065 0.0196 0.1054
Schistosoma mansoni hypothetical protein 0.0041 0.0083 0.008
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0147 0.0478
Echinococcus multilocularis potassium voltage gated channel protein 0.0084 0.0289 0.0286
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0233 0.023
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0239 0.1032 0.6289
Brugia malayi nuclear hormone receptor family member odr-7 0.0191 0.0802 0.0793
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0014 0.0002
Loa Loa (eye worm) nuclear hormone receptor 0.0191 0.0802 0.0793
Loa Loa (eye worm) hypothetical protein 0.0258 0.1124 0.1115
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.004 0.0079 0.012
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Brugia malayi beta-lactamase family protein 0.0072 0.0233 0.0223
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0077 0.0256 0.0246
Loa Loa (eye worm) hypothetical protein 0.0414 0.1874 0.1865
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0026 0.001 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0084 0.0289 0.0279
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0041 0.0083 0.0073
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0124 0.0482 0.0479
Loa Loa (eye worm) hypothetical protein 0.0054 0.0147 0.0137
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0365 0.1641 0.1638
Giardia lamblia DINP protein human, muc B family 0.0044 0.0097 0.0115
Schistosoma mansoni sodium/chloride dependent transporter 0.0153 0.0621 0.0618
Schistosoma mansoni cell polarity protein 0.0052 0.0134 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0002
Echinococcus granulosus TRP transient receptor potential channel 0.0084 0.0289 0.0286
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0034 0.0076
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0127 0.0494 0.2348
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0059 0.0056
Echinococcus multilocularis musashi 0.0194 0.0817 0.0815
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Echinococcus multilocularis short transient receptor potential channel 6 0.0084 0.0289 0.0286
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.001 0.0007
Onchocerca volvulus 0.0028 0.002 0.0018
Echinococcus granulosus slit 2 protein 0.0052 0.0134 0.0131
Echinococcus granulosus pikachurin 0.0052 0.0134 0.0131
Onchocerca volvulus 0.0356 0.1594 0.2846
Echinococcus multilocularis conserved hypothetical protein 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.001
Leishmania major cytochrome p450-like protein 0.0059 0.0169 0.0554
Echinococcus granulosus mixed lineage leukemia protein mll 0.0035 0.0053 0.005
Plasmodium falciparum transporter, putative 0.0026 0.001 0.0062
Loa Loa (eye worm) hypothetical protein 0.0223 0.0957 0.0948
Loa Loa (eye worm) carboxylesterase 0.0356 0.1594 0.1586
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0077 0.0256 0.0253
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0041 0.0083 0.008
Brugia malayi hypothetical protein 0.0035 0.0054 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0083 0.008
Mycobacterium ulcerans oxidoreductase 0.0144 0.0578 0.3525
Plasmodium falciparum importin beta, putative 0.0088 0.0308 0.1876
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.0427 0.0424
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.004 0.0079 0.0261
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0084 0.0289 0.0286
Echinococcus multilocularis potassium voltage gated channel protein 0.0084 0.0289 0.0286
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0147 0.0478
Loa Loa (eye worm) RNA binding protein 0.0194 0.0818 0.0809
Loa Loa (eye worm) hypothetical protein 0.0049 0.0119 0.0109
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0458 0.2177
Echinococcus multilocularis importin subunit beta 1 0.0088 0.0308 0.0305
Loa Loa (eye worm) hypothetical protein 0.0342 0.153 0.1522
Onchocerca volvulus Putative organic anion transporter 0.0028 0.002 0.0018
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0083 0.008
Schistosoma mansoni calcium-activated potassium channel 0.0084 0.0289 0.0286
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0124 0.0482 0.1668
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0143 0.0575 0.0572
Loa Loa (eye worm) hypothetical protein 0.0156 0.0634 0.0624
Echinococcus granulosus expressed conserved protein 0.0292 0.1287 0.1285
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0084 0.0289 0.0286
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0233 0.1105
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0041 0.0083 0.0395
Brugia malayi hypothetical protein 0.0028 0.002 0.001
Schistosoma mansoni hypothetical protein 0.0132 0.0522 0.0519
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0081 0.0079
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0365 0.1641 1
Loa Loa (eye worm) hypothetical protein 0.0414 0.1874 0.1865
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0233 0.1105
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0185 0.0776 0.4731
Loa Loa (eye worm) hypothetical protein 0.0223 0.0957 0.0948
Brugia malayi voltage-dependent calcium channel 0.0084 0.0289 0.0279
Echinococcus multilocularis voltage dependent calcium channel 0.0084 0.0289 0.0286
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0084 0.0289 0.0286
Leishmania major hypothetical protein, conserved 0.0054 0.0147 0.0478
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0691
Schistosoma mansoni polycystin 1-related 0.0041 0.0081 0.0079
Schistosoma mansoni transient receptor potential channel 4 0.0084 0.0289 0.0286
Echinococcus granulosus snurportin 1 0.0939 0.4397 0.4395
Entamoeba histolytica deoxycytidyl transferase, putative 0.0036 0.006 0.0024
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0041 0.0083 0.0073
Loa Loa (eye worm) hypothetical protein 0.0072 0.0233 0.0223
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0191 0.0802 0.0793
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.033 0.1474 0.1471
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0365 0.1641 0.2926
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0075 0.0248 0.1509
Schistosoma mansoni nuclear receptor 0.0191 0.0802 0.0799
Echinococcus multilocularis transient receptor potential cation channel 0.0084 0.0289 0.0286
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0414 0.1874 0.1871
Echinococcus granulosus ecdysone induced protein 78C 0.0414 0.1874 0.1871
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0041 0.0194
Mycobacterium tuberculosis Conserved hypothetical protein 0.0036 0.006 0.0286
Schistosoma mansoni tar DNA-binding protein 0.0194 0.0818 0.0816
Brugia malayi regulator of G-protein signaling rgs-7 0.0041 0.0083 0.0073
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0081 0.0079
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0044 0.0097 0.0301
Brugia malayi Carboxylesterase family protein 0.0356 0.1594 0.1586
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.021 0.0722
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.021 0.0722
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0256 0.0865
Echinococcus multilocularis expressed protein 0.0802 0.3739 0.3737
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0191 0.0802 0.0793
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Schistosoma mansoni RAR-like nuclear receptor 0.0414 0.1874 0.1871
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0089 0.0294
Onchocerca volvulus Protein ultraspiracle homolog 0.0414 0.1874 0.3348
Onchocerca volvulus 0.0194 0.0817 0.145
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.002 0.001
Echinococcus granulosus activated cdc42 kinase 1 0.035 0.1567 0.1565
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0356 0.1594 0.1592
Trichomonas vaginalis spcc417.12 protein, putative 0.0356 0.1594 0.2843
Schistosoma mansoni DNA polymerase eta 0.0062 0.0184 0.0181
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0065 0.0196 0.1196
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0063 0.0385
Brugia malayi hypothetical protein 0.0041 0.0083 0.0073
Echinococcus granulosus beta-adrenergic receptor kinase 0.0041 0.0083 0.008
Loa Loa (eye worm) ion channel NompC 0.0084 0.0289 0.0279
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0041 0.0083 0.0506
Plasmodium falciparum glutathione reductase 0.0047 0.0111 0.0678
Brugia malayi Inositol-1 0.0036 0.0059 0.0049
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0058 0.0164 0.0162
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0081 0.0079
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Echinococcus granulosus sodium and chloride dependent glycine 0.0026 0.001 0.0007
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0185 0.0776 0.4731
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0094 0.0335 0.0332
Echinococcus granulosus carboxylesterase 5A 0.2104 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0014 0.0002
Echinococcus multilocularis shaker cognate 0.0084 0.0289 0.0286
Echinococcus multilocularis thyroid hormone receptor alpha 0.0546 0.251 0.2508
Brugia malayi glutathione reductase 0.0047 0.0111 0.0101
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0059 0.0169 0.1028
Echinococcus granulosus potassium voltage gated channel protein 0.0084 0.0289 0.0286
Schistosoma mansoni aryl hydrocarbon receptor 0.0103 0.0381 0.0379
Schistosoma mansoni inositol monophosphatase 0.0036 0.0059 0.0056
Leishmania major importin beta-1 subunit, putative 0.0071 0.0228 0.0765
Echinococcus multilocularis para nitrobenzyl esterase 0.0356 0.1594 0.1592
Toxoplasma gondii hypothetical protein 0.0115 0.044 0.2681
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0365 0.1641 0.1638
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0084 0.0289 0.0286
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0185 0.0776 0.4731
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.0136 0.0538 0.0528
Onchocerca volvulus Putative organic anion transporter 0.0028 0.002 0.0018
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0365 0.1641 1
Loa Loa (eye worm) hypothetical protein 0.0675 0.313 0.3123
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0223 0.0957 0.0954
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0115 0.044 0.0768
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0084 0.0289 0.0286
Loa Loa (eye worm) cytochrome P450 0.0041 0.0083 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0691
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0083 0.0127
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0155 0.063 0.111
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0233 0.0782
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.004 0.0079 0.0077
Onchocerca volvulus 0.0153 0.0621 0.1097
Entamoeba histolytica hypothetical protein 0.0113 0.0427 0.2798
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0084 0.0289 0.0279
Onchocerca volvulus Putative organic anion transporter 0.0425 0.1928 0.3444
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0057 0.0158
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0065 0.0199 0.0684
Trichomonas vaginalis esterase, putative 0.0072 0.0233 0.0396
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0201 0.0668
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0185 0.0776 0.4731
Trichomonas vaginalis ap endonuclease, putative 0.0075 0.0248 0.0422
Loa Loa (eye worm) MH2 domain-containing protein 0.0235 0.1014 0.1005
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0071 0.0228 0.0387
Onchocerca volvulus 0.0028 0.002 0.0018
Echinococcus multilocularis transcription factor Dp 1 0.0045 0.01 0.0097
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0084 0.0289 0.0286
Onchocerca volvulus 0.0356 0.1594 0.2846
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0084 0.0289 0.0286
Onchocerca volvulus 0.0028 0.002 0.0018
Brugia malayi Glycosyl hydrolases family 31 protein 0.0161 0.066 0.065
Trypanosoma cruzi DNA polymerase kappa, putative 0.0067 0.021 0.07
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0065 0.0199 0.0684
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0083 0.0127
Plasmodium vivax importin-beta 2, putative 0.0088 0.0308 0.1876
Loa Loa (eye worm) carboxylesterase 0.0356 0.1594 0.1586
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0104 0.0385 0.0375
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0065 0.0196 0.0186
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0197 0.0832 0.0829
Loa Loa (eye worm) hypothetical protein 0.0052 0.0134 0.0124
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0458 0.2177
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0057 0.0047
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0156 0.0634 0.3864
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0002
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0026 0.001 0.0007
Trichomonas vaginalis importin beta-1, putative 0.0071 0.0228 0.0387
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0414 0.1874 0.1871
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0026 0.001 0.0007
Entamoeba histolytica hypothetical protein 0.0113 0.0427 0.2798
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0191 0.0802 0.0799
Schistosoma mansoni cpg binding protein 0.0125 0.0486 0.0483
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0147 0.0501
Echinococcus multilocularis slit 2 protein 0.0052 0.0134 0.0131
Trypanosoma cruzi MFS transporter, putative 0.0028 0.002 0.0026
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0401 0.1904
Brugia malayi Carboxylesterase family protein 0.0356 0.1594 0.1586
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0414 0.1874 0.1871
Echinococcus granulosus cytochrome P450 2K1 0.0041 0.0083 0.008
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.033 0.1474 0.5195
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0084 0.0289 0.05
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0132 0.0522 0.0519
Toxoplasma gondii histone lysine methyltransferase SET1 0.0229 0.0988 0.602
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0185 0.0776 0.4731
Onchocerca volvulus 0.0041 0.0081 0.0128
Brugia malayi photoreceptor-specific nuclear receptor 0.0414 0.1874 0.1865
Trypanosoma cruzi DNA polymerase kappa, putative 0.0067 0.021 0.07
Onchocerca volvulus 0.0356 0.1594 0.2846
Onchocerca volvulus 0.0072 0.0233 0.04
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0084 0.0289 0.0286
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0071 0.0228 0.0387
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.004 0.0079 0.0069
Leishmania major protein farnesyltransferase alpha subunit, putative 0.004 0.0079 0.0237
Schistosoma mansoni rab6-interacting 0.0041 0.0081 0.0079
Brugia malayi tailless protein 0.0191 0.0802 0.0793
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0082 0.0277 0.0275
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0034 0.0099
Schistosoma mansoni cpg binding protein 0.0118 0.0453 0.0451
Schistosoma mansoni voltage-dependent calcium channel 0.0084 0.0289 0.0286
Toxoplasma gondii hypothetical protein 0.0026 0.001 0.0062
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0185 0.0776 0.3687
Brugia malayi ecdysone receptor 0.0191 0.0802 0.0793
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0059 0.0189
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0059 0.0083
Brugia malayi follicle stimulating hormone receptor 0.074 0.344 0.3433
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0185 0.0776 0.3687
Loa Loa (eye worm) DR-78 0.0191 0.0802 0.0793
Echinococcus multilocularis neurogenic locus notch protein 0.0052 0.0134 0.0131
Echinococcus granulosus transient receptor potential cation channel 0.0084 0.0289 0.0286
Echinococcus granulosus Nuclear hormone receptor HR96 0.0191 0.0802 0.0799
Echinococcus multilocularis transient receptor potential cation channel 0.0084 0.0289 0.0287
Loa Loa (eye worm) calcium channel 0.0084 0.0289 0.0279
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0111 0.0529
Schistosoma mansoni coup transcription factor 0.0414 0.1874 0.1871
Loa Loa (eye worm) hypothetical protein 0.0223 0.0957 0.0948
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0691
Toxoplasma gondii hypothetical protein 0.0099 0.0359 0.2191
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0191 0.0802 0.1423
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0084 0.0289 0.0279
Echinococcus multilocularis acetylcholinesterase 0.2104 1 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0308 0.0298
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0034 0.0076
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0053 0.0138 0.023
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0084 0.0289 0.0286
Brugia malayi Cytochrome P450 family protein 0.0059 0.0169 0.0159
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0084 0.0289 0.0279
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0028 0.002 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0067 0.021 0.07
Schistosoma mansoni hypothetical protein 0.1245 0.5869 0.5868
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0065 0.0196 0.0653
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0052 0.0134 0.0124
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0083 0.008
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0414 0.1874 0.1865
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0691
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0084 0.0289 0.0286
Trichomonas vaginalis DNA polymerase eta, putative 0.0067 0.021 0.0354
Brugia malayi hypothetical protein 0.0223 0.0957 0.0948
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0026 0.001 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0185 0.0776 0.3687
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0414 0.1874 0.1865
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.006 0.0173 0.0571
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0041 0.0083 0.0506
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0185 0.0776 0.3687
Loa Loa (eye worm) hypothetical protein 0.0041 0.0081 0.0071
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0057 0.008
Toxoplasma gondii cytochrome p450 superfamily protein 0.0041 0.0083 0.0506
Schistosoma mansoni lipoxygenase 0.0058 0.0164 0.0162
Schistosoma mansoni tyrosine kinase 0.0136 0.0538 0.0535
Trypanosoma cruzi DNA polymerase kappa, putative 0.0067 0.021 0.07
Echinococcus granulosus histone lysine methyltransferase setb 0.0151 0.0613 0.0611
Loa Loa (eye worm) voltage-gated potassium channel 0.0084 0.0289 0.0279
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0073
Echinococcus multilocularis sodium channel protein 0.0084 0.0289 0.0286
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0041 0.0369
Brugia malayi beta-lactamase family protein 0.0072 0.0233 0.0223
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0406 0.1836 0.1828
Chlamydia trachomatis DNA gyrase subunit B 0.0039 0.0075 0.0454
Trichomonas vaginalis helicase, putative 0.0027 0.0014 0.0002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0414 0.1874 0.1871
Loa Loa (eye worm) voltage-dependent calcium channel 0.0084 0.0289 0.0279
Echinococcus granulosus voltage gated potassium channel 0.0084 0.0289 0.0286
Brugia malayi isocitrate dehydrogenase 0.0031 0.0034 0.0024
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0401 0.1904
Echinococcus multilocularis dna polymerase eta 0.0062 0.0184 0.0181
Echinococcus multilocularis GPCR, family 2 0.0082 0.0277 0.0275
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0041 0.0083 0.025
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0044 0.0097 0.0462
Trypanosoma brucei DNA topoisomerase ii 0.0057 0.0159 0.0545
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0028 0.0019 0.0016
Brugia malayi prostaglandin transporter 0.0425 0.1928 0.1919
Echinococcus granulosus hyperpolarization activated cyclic 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.009 0.0318 0.0308
Echinococcus granulosus ankyrin repeat protein 0.016 0.0654 0.0652
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0073
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0185 0.0776 0.3687
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0132 0.0522 0.0519
Echinococcus multilocularis serotonin transporter 0.0153 0.0621 0.0618
Brugia malayi Cytochrome P450 family protein 0.0041 0.0083 0.0073
Brugia malayi F/Y-rich N-terminus family protein 0.0042 0.0085 0.0075
Echinococcus multilocularis dna polymerase kappa 0.0067 0.021 0.0207
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0124 0.0482 0.0479
Schistosoma mansoni terminal deoxycytidyl transferase 0.0036 0.006 0.0057
Mycobacterium ulcerans hypothetical protein 0.0322 0.1434 0.8739
Echinococcus granulosus FTZ F1 alpha 0.0414 0.1874 0.1871
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0075 0.0248 0.0245
Echinococcus multilocularis 0.0041 0.0083 0.008
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0185 0.0776 0.4731
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.001 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0414 0.1874 0.1865
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0554 0.2546 0.2544
Echinococcus granulosus two pore calcium channel protein 1 0.0084 0.0289 0.0286
Echinococcus granulosus dnaJ subfamily B 0.1245 0.5869 0.5868
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0073 0.0234 0.0231
Echinococcus granulosus potassium voltage gated channel protein 0.0084 0.0289 0.0286
Echinococcus multilocularis nuclear receptor nhr 48 0.0191 0.0802 0.0799
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0057 0.0047
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.066 0.0657
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0084 0.0289 0.0279
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0233 0.0396
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0084 0.0289 0.0286
Brugia malayi beta-lactamase 0.0072 0.0233 0.0223
Echinococcus granulosus transient receptor potential gamma protein 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Loa Loa (eye worm) hypothetical protein 0.0094 0.0335 0.0325
Echinococcus granulosus single minded 2 0.0075 0.0248 0.0245
Giardia lamblia Rab geranylgeranyltransferase 0.0156 0.0634 0.3552
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0077 0.0256 0.0253
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0041 0.0083 0.0395
Plasmodium falciparum DNA topoisomerase 2 0.0073 0.0234 0.1426
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0075 0.0248 0.1509
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0035 0.0053 0.005
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0084 0.0289 0.0286
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0083 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0002
Echinococcus granulosus hypothetical protein 0.0084 0.0289 0.0286
Schistosoma mansoni hypothetical protein 0.1049 0.4928 0.4927
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0059 0.2387
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0077 0.0254 0.0252
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0083 0.008
Echinococcus multilocularis aryl hydrocarbon receptor 0.0028 0.0019 0.0016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0197 0.0832 0.0829
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0035 0.0053 0.005
Echinococcus granulosus Protein patched homolog 1 0.0269 0.118 0.1177
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.021 0.0722
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0223 0.0957 0.0954
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0185 0.0776 0.3687
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0084 0.0289 0.0286
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0414 0.1874 0.1871
Mycobacterium ulcerans carboxylesterase, LipT 0.0356 0.1594 0.9717
Loa Loa (eye worm) PXA domain-containing protein 0.0041 0.0083 0.0073
Schistosoma mansoni hypothetical protein 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.0414 0.1874 0.1865
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0041 0.0083 0.0506
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0185 0.0776 0.4731
Brugia malayi bHLH-PAS transcription factor 0.0075 0.0248 0.0238
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0151 0.0613 0.0611
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0124 0.0482 0.1668
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0057 0.008
Brugia malayi ecdysteroid receptor 0.0897 0.4199 0.4193
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0028 0.002 0.0017
Schistosoma mansoni hypothetical protein 0.0082 0.0277 0.0275
Brugia malayi MH2 domain containing protein 0.0235 0.1014 0.1005
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0084 0.0289 0.0286
Toxoplasma gondii exonuclease III APE 0.0075 0.0248 0.1509
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0059 0.036
Echinococcus granulosus lamin dm0 0.0194 0.0817 0.0815
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0084 0.0289 0.0286
Brugia malayi Protein kinase domain containing protein 0.035 0.1567 0.1558
Brugia malayi nuclear receptor RXR 0.0223 0.0957 0.0948
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0414 0.1874 0.1871
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0191 0.0802 0.0799
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0118 0.045 0.1555
Echinococcus granulosus geminin 0.1049 0.4928 0.4927
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0034 0.0207
Echinococcus granulosus voltage gated potassium channel 0.0084 0.0289 0.0286
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0059 0.0083
Echinococcus multilocularis transient receptor potential gamma protein 0.0084 0.0289 0.0286
Loa Loa (eye worm) latrophilin receptor protein 2 0.0082 0.0277 0.0267
Echinococcus multilocularis regulator of G protein signaling 0.0041 0.0083 0.008
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0082 0.0277 0.0267
Echinococcus granulosus short transient receptor potential channel 6 0.0084 0.0289 0.0287
Plasmodium falciparum thioredoxin reductase 0.0047 0.0111 0.0678
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0079 0.0237
Echinococcus multilocularis ryanodine receptor 44f 0.0084 0.0289 0.0286
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0084 0.0289 0.0279
Echinococcus granulosus ryanodine receptor 44f 0.0084 0.0289 0.0286
Mycobacterium tuberculosis Probable oxidoreductase 0.0144 0.0578 0.2748
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0042 0.0087 0.0085
Echinococcus multilocularis calcium activated potassium channel 0.0084 0.0289 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0002
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0084 0.0289 0.1003
Loa Loa (eye worm) hypothetical protein 0.0072 0.0233 0.0223
Leishmania major cathepsin L-like protease 0.0066 0.0201 0.0668
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0414 0.1874 0.1871
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0414 0.1874 0.1871
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0197 0.0832 0.0822
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0233 0.1418
Leishmania major DNA topoisomerase ii 0.0065 0.0199 0.0662
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0073 0.0234 0.0224
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0034 0.0099
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0111 0.0109
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.066 0.0657
Leishmania major mitochondrial DNA topoisomerase II 0.0057 0.0159 0.0522
Loa Loa (eye worm) hypothetical protein 0.009 0.0318 0.0308
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0414 0.1874 0.1871
Echinococcus multilocularis ankyrin repeat protein 0.016 0.0654 0.0652
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Echinococcus granulosus acetylcholinesterase 0.2104 1 1
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0191 0.0802 0.0799
Trypanosoma cruzi DNA polymerase eta, putative 0.0062 0.0184 0.0609
Schistosoma mansoni hypothetical protein 0.0082 0.0277 0.0275
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0124 0.0482 0.0843
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0084 0.0289 0.0496
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0041 0.0083 0.0073
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0185 0.0776 0.4731
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0034 0.0031
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0414 0.1874 0.1865
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0233 0.1418
Echinococcus granulosus serotonin transporter 0.0153 0.0621 0.0618
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0083 0.008
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0081 0.0079
Trypanosoma cruzi cruzipain precursor, putative 0.0066 0.0201 0.0668
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0406 0.1836 0.1834
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0084 0.0289 0.0286
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0036 0.006 0.0057
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0156 0.0634 0.4368
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0083 0.008
Loa Loa (eye worm) hypothetical protein 0.0151 0.0613 0.0604
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0079 0.0237
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0075 0.0248 0.0857
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0083 0.008
Schistosoma mansoni rab6-interacting 0.0041 0.0081 0.0079
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0053 0.0138 0.023
Entamoeba histolytica hypothetical protein 0.0071 0.0228 0.1293
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0086 0.0299 0.1017
Trypanosoma cruzi DNA topoisomerase II, putative 0.0065 0.0199 0.0662
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0041 0.0083 0.0395
Onchocerca volvulus 0.0072 0.0233 0.04
Brugia malayi nuclear receptor NHR-88 0.0414 0.1874 0.1865
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0156 0.0634 0.0624
Echinococcus granulosus sterol regulatory element binding protein 0.0269 0.118 0.1177
Echinococcus multilocularis transient receptor potential cation channel 0.0084 0.0289 0.0286
Schistosoma mansoni hypothetical protein 0.0113 0.0427 0.0424
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0414 0.1874 0.1871
Loa Loa (eye worm) hypothetical protein 0.0194 0.0817 0.0808
Brugia malayi CXXC zinc finger family protein 0.0118 0.0453 0.0444
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0414 0.1874 0.1871
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0059 0.0083
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0059 0.0056
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.033 0.1474 0.1465
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0079 0.0261
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0256 0.0865
Loa Loa (eye worm) hypothetical protein 0.0049 0.0119 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0151 0.0613 0.0611
Loa Loa (eye worm) carboxylesterase 0.2104 1 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0073
Echinococcus granulosus voltage dependent calcium channel 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.001
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0083 0.008
Echinococcus granulosus para nitrobenzyl esterase 0.0356 0.1594 0.1592
Brugia malayi Carboxylesterase family protein 0.0356 0.1594 0.1586
Schistosoma mansoni sodium/chloride dependent transporter 0.0026 0.001 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0482 0.0843
Echinococcus multilocularis RUN 0.0041 0.0081 0.0079
Loa Loa (eye worm) hypothetical protein 0.0414 0.1874 0.1865
Echinococcus granulosus Niemann Pick C1 protein 0.0311 0.1378 0.1376
Trypanosoma brucei unspecified product 0.006 0.0173 0.0591
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0233 0.1105
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0151 0.0613 0.0611
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0414 0.1874 0.1871
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0156 0.0634 0.1117
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0691
Loa Loa (eye worm) hypothetical protein 0.0062 0.0184 0.0174
Echinococcus granulosus transient receptor potential cation channel 0.0084 0.0289 0.0286
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.021 0.0722
Brugia malayi Doublecortin family protein 0.0041 0.0081 0.0071
Brugia malayi exodeoxyribonuclease III family protein 0.0075 0.0248 0.0238
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1041 0.4887 0.4882
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0289 0.1277 0.4494
Leishmania major cathepsin L-like protease 0.0066 0.0201 0.0668
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0084 0.0289 0.0279
Loa Loa (eye worm) hypoxia-induced factor 1 0.0316 0.1403 0.1394
Echinococcus multilocularis Niemann Pick C1 protein 0.058 0.2672 0.267
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0077 0.0256 0.1506
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0214 0.0914 0.3204
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Schistosoma mansoni retinoic acid receptor RXR 0.0414 0.1874 0.1871
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0041 0.0083 0.008
Schistosoma mansoni BC026374 protein (S09 family) 0.0356 0.1594 0.1592
Trypanosoma cruzi cytochrome P450, putative 0.0059 0.0169 0.0554
Schistosoma mansoni inositol monophosphatase 0.0036 0.0059 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0414 0.1874 0.1865
Brugia malayi nuclear hormone receptor 0.0191 0.0802 0.0793
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0097 0.0324
Loa Loa (eye worm) ryanodine receptor 0.0084 0.0289 0.0279
Loa Loa (eye worm) hypothetical protein 0.0414 0.1874 0.1865
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0233 0.023
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0058 0.0164 0.0162
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0185 0.0776 0.4731
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0256 0.1117 0.1114
Onchocerca volvulus 0.0191 0.0802 0.1423
Brugia malayi hypothetical protein 0.0191 0.0802 0.0793
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0233 0.1418
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0084 0.0289 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0002
Schistosoma mansoni 60S ribosomal protein L21 0.0084 0.0289 0.0286
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0365 0.1641 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0063 0.018
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0356 0.1594 0.1592
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Toxoplasma gondii thioredoxin reductase 0.0047 0.0111 0.0678
Schistosoma mansoni nuclear hormone receptor 0.0191 0.0802 0.0799
Toxoplasma gondii hypothetical protein 0.0084 0.0289 0.176
Toxoplasma gondii hypothetical protein 0.0084 0.0289 0.176
Trichomonas vaginalis DNA topoisomerase II, putative 0.0073 0.0234 0.0398
Trypanosoma brucei importin beta-1 subunit, putative 0.0088 0.0308 0.1071
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0034 0.0161
Schistosoma mansoni thyroid hormone receptor 0.0546 0.251 0.2508
Echinococcus granulosus dna polymerase kappa 0.0067 0.021 0.0207
Echinococcus multilocularis ecdysone induced protein 78C 0.0414 0.1874 0.1871
Schistosoma mansoni ap endonuclease 0.0075 0.0248 0.0245
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0406 0.1836 0.1834
Schistosoma mansoni hypothetical protein 0.0041 0.0081 0.0079
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0073 0.0234 0.0231
Brugia malayi hypothetical protein 0.0041 0.0081 0.0071
Echinococcus granulosus neurogenic locus notch protein 0.0052 0.0134 0.0131
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0414 0.1874 0.1865
Schistosoma mansoni loxhd1 0.0041 0.0081 0.0079
Loa Loa (eye worm) hypothetical protein 0.0425 0.1928 0.1919
Brugia malayi cation channel family protein 0.0084 0.0289 0.0279
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0191 0.0802 0.1423
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0197 0.0832 0.0829
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0026 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0356 0.1594 0.1586
Schistosoma mansoni hypothetical protein 0.0128 0.0503 0.05
Echinococcus multilocularis activated cdc42 kinase 1 0.035 0.1567 0.1565
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0691
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0036 0.006 0.005
Schistosoma mansoni transient receptor potential channel 0.0084 0.0289 0.0287
Loa Loa (eye worm) hypothetical protein 0.0348 0.1558 0.155
Loa Loa (eye worm) hypothetical protein 0.0897 0.4199 0.4193
Schistosoma mansoni cytochrome P450 0.0041 0.0083 0.008
Entamoeba histolytica DNA topoisomerase II, putative 0.0073 0.0234 0.1339
Schistosoma mansoni voltage-gated cation channel 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.001
Entamoeba histolytica hypothetical protein 0.0113 0.0427 0.2798
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.033 0.1474 0.5195
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0356 0.1594 0.1592
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0233 0.1105
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0083 0.008
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0414 0.1874 0.1865
Trypanosoma brucei cytochrome P450, putative 0.0059 0.0169 0.0577
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0083 0.008
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0365 0.1641 0.5799
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0057 0.0158
Onchocerca volvulus 0.0072 0.0233 0.04
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0083 0.0127
Plasmodium vivax hypothetical protein, conserved 0.0026 0.001 0.0062
Trypanosoma brucei glucosidase, putative 0.0036 0.0057 0.0182
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0084 0.0289 0.0982
Schistosoma mansoni tar DNA-binding protein 0.0194 0.0818 0.0816
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0084 0.0289 0.176
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0057 0.0158
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0084 0.0289 0.0279
Echinococcus multilocularis transfer RNA-Gly 0.0084 0.0289 0.0286
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0034 0.0031
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.001 0.0007
Echinococcus multilocularis lamin dm0 0.0194 0.0817 0.0815
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0185 0.0776 0.3687
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0133 0.0428
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0053 0.0138 0.023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0414 0.1874 0.1865
Leishmania major cytochrome p450-like protein 0.0041 0.0083 0.025
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0258 0.1124 0.1115
Brugia malayi hypothetical protein 0.0223 0.0957 0.0948
Loa Loa (eye worm) hypothetical protein 0.0041 0.0081 0.0071
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0083 0.0073
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0197 0.0832 0.0829
Schistosoma mansoni ran 0.0065 0.0196 0.0194
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0084 0.0289 0.0286
Echinococcus granulosus thyroid hormone receptor alpha 0.0191 0.0802 0.0799
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0356 0.1594 0.1592
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0414 0.1874 0.1871
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0014 0.0002
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0082 0.0277 0.0275
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0401 0.1904
Schistosoma mansoni sodium/chloride dependent transporter 0.0026 0.001 0.0007
Echinococcus multilocularis potassium voltage gated channel protein 0.0084 0.0289 0.0286
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0365 0.1641 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0077 0.0256 0.0253
Echinococcus granulosus GPCR family 2 0.0082 0.0277 0.0275
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0185 0.0776 0.4731
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0084 0.0289 0.0279
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0043 0.0131
Schistosoma mansoni nuclear hormone receptor 0.0191 0.0802 0.0799
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0075 0.0248 1
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0084 0.0289 0.0286
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0223 0.0957 0.0954
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.019 0.08 0.0791
Loa Loa (eye worm) norepinephrine transporter 0.0153 0.0621 0.0611
Echinococcus granulosus aryl hydrocarbon receptor 0.0028 0.0019 0.0016
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0084 0.0289 0.0286
Mycobacterium ulcerans lipase LipD 0.0072 0.0233 0.1418
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0067 0.021 0.0354
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0124 0.0482 0.0479
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0075 0.0248 0.0245
Trypanosoma brucei importin beta-1 subunit, putative 0.0088 0.0308 0.1071
Loa Loa (eye worm) hypothetical protein 0.0153 0.0621 0.0611
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0414 0.1874 0.1865
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0028 0.002 0.001
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0173 0.0591
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0083 0.008
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.003 0.0028 0.0171
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0147 0.0897
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.004 0.0079 0.0169
Loa Loa (eye worm) hypothetical protein 0.0042 0.0089 0.0079
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0365 0.1641 0.1632
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.004 0.0079 0.0237
Brugia malayi ion channel NompC 0.0084 0.0289 0.0279
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0084 0.0289 0.0286
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0057 0.008
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0233 0.0396
Toxoplasma gondii hypothetical protein 0.004 0.0079 0.0484
Trypanosoma brucei trypanothione reductase 0.0047 0.0111 0.0374
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0081 0.0079
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0084 0.0289 0.0286
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0059 0.036
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0185 0.0776 0.4731
Onchocerca volvulus 0.0118 0.0453 0.0796
Echinococcus multilocularis geminin 0.1049 0.4928 0.4927
Schistosoma mansoni neuroligin 3 (S09 family) 0.0356 0.1594 0.1592
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0197 0.0832 0.0829
Loa Loa (eye worm) hypothetical protein 0.0223 0.0957 0.0948
Loa Loa (eye worm) hypothetical protein 0.0311 0.1378 0.1369
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0194 0.0818 0.0809
Schistosoma mansoni alpha-glucosidase 0.0139 0.0552 0.0549
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0084 0.0289 0.0286
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0081 0.0497
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0059 0.0165
Schistosoma mansoni microtubule-associated protein tau 0.2084 0.99 0.99
Schistosoma mansoni zinc finger protein 0.0191 0.0802 0.0799
Echinococcus granulosus potassium voltage gated channel protein 0.0084 0.0289 0.0286
Schistosoma mansoni lipoxygenase 0.0041 0.0081 0.0079
Loa Loa (eye worm) follicle stimulating hormone receptor 0.074 0.344 0.3433
Brugia malayi hypothetical protein 0.0028 0.002 0.001
Loa Loa (eye worm) beta-lactamase 0.0072 0.0233 0.0223
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0065 0.0196 0.1196
Brugia malayi nuclear hormone receptor family member nhr-6 0.0191 0.0802 0.0793
Schistosoma mansoni hypothetical protein 0.0113 0.0428 0.0425
Echinococcus multilocularis protein KINase family member (kin 25) 0.0136 0.0538 0.0535
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0081 0.0071
Brugia malayi Probable DNA topoisomerase II 0.0073 0.0234 0.0224
Loa Loa (eye worm) hypothetical protein 0.0148 0.0596 0.0586
Echinococcus multilocularis voltage gated potassium channel 0.0084 0.0289 0.0286
Onchocerca volvulus 0.0194 0.0817 0.145
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0401 0.5084
Loa Loa (eye worm) voltage-gated calcium channel 0.0084 0.0289 0.0279
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0233 0.023
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0414 0.1874 0.1865
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0084 0.0289 0.0279
Brugia malayi glucose-6-phosphate dehydrogenase 0.0365 0.1641 0.1632
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0041 0.0083 0.008
Echinococcus multilocularis potassium voltage gated channel protein 0.0084 0.0289 0.0286
Onchocerca volvulus 0.1184 0.5577 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0169 0.0159
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0084 0.0289 0.0286
Echinococcus granulosus sodium channel protein 0.0084 0.0289 0.0286
Echinococcus granulosus lysosomal alpha glucosidase 0.0161 0.066 0.0657
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0034 0.0024
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0077 0.0256 0.0887
Schistosoma mansoni tar DNA-binding protein 0.0194 0.0818 0.0816
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0136 0.0538 0.0535
Echinococcus multilocularis ubiquitin specific protease 41 0.0124 0.0482 0.0479
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0233 0.0782
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0082 0.0277 0.0275
Brugia malayi hypothetical protein 0.0041 0.0081 0.0071
Trichomonas vaginalis set domain proteins, putative 0.1184 0.5576 1
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.016 0.0654 0.0652
Echinococcus granulosus RUN 0.0041 0.0081 0.0079
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0084 0.0289 0.0286
Echinococcus multilocularis two pore calcium channel protein 2 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.0153 0.0621 0.0611
Mycobacterium ulcerans DNA polymerase IV 0.0067 0.021 0.1277
Echinococcus multilocularis Regulator of G protein signaling 20 0.0041 0.0083 0.008
Loa Loa (eye worm) hypothetical protein 0.0269 0.118 0.1171
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0084 0.0289 0.0286
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.033 0.1474 0.5206
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0161 0.066 0.065
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0111 0.0109
Brugia malayi hypothetical protein 0.0191 0.0802 0.0793
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0014 0.0002
Schistosoma mansoni voltage-gated ion channel 0.0084 0.0289 0.0286
Brugia malayi hypothetical protein 0.0041 0.0083 0.0073
Brugia malayi ImpB/MucB/SamB family protein 0.0062 0.0184 0.0174
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0084 0.0289 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.0269 0.118 0.2098
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0026 0.001 0.0007
Plasmodium vivax SET domain protein, putative 0.0151 0.0613 0.3738
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0042 0.0087 0.0085
Schistosoma mansoni transient receptor potential channel 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.0134 0.0529 0.052
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0201 0.0668
Plasmodium vivax glutathione reductase, putative 0.0047 0.0111 0.0678
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0084 0.0289 0.0286
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0214 0.0914 0.3204
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0034 0.0207
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0239 0.1032 0.6289
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.006 0.005
Loa Loa (eye worm) hypothetical protein 0.0414 0.1874 0.1865
Onchocerca volvulus Bile acid receptor homolog 0.0897 0.4199 0.7524
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0406 0.1836 0.1828
Brugia malayi intermediate filament protein 0.0194 0.0817 0.0808
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0057 0.008
Brugia malayi TAR-binding protein 0.0194 0.0818 0.0809
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0057 0.008
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0084 0.0289 0.0279
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0084 0.0289 0.0286
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0365 0.1641 0.5789
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0939 0.4397 0.4391
Echinococcus multilocularis transient receptor potential cation channel 0.0084 0.0289 0.0286
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0057 0.008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0691
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0147 0.0897
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Mycobacterium ulcerans DNA polymerase IV 0.0067 0.021 0.1277
Entamoeba histolytica hypothetical protein 0.0041 0.0083 0.0197
Onchocerca volvulus 0.0151 0.0613 0.1083
Loa Loa (eye worm) hypothetical protein 0.0134 0.0529 0.052
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0365 0.1641 0.5789
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0185 0.0776 0.4731
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0043 0.0131
Echinococcus multilocularis BC026374 protein (S09 family) 0.0356 0.1594 0.1592
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0414 0.1874 0.1865
Schistosoma mansoni transient receptor potential channel 0.0084 0.0289 0.0286
Entamoeba histolytica hypothetical protein 0.0113 0.0427 0.2798
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0026 0.001 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Echinococcus multilocularis snurportin 1 0.0939 0.4397 0.4395
Loa Loa (eye worm) hypothetical protein 0.0163 0.067 0.066
Echinococcus multilocularis beta adrenergic receptor kinase 0.0041 0.0083 0.008
Leishmania major GTP-binding protein, putative 0.0065 0.0196 0.0653
Schistosoma mansoni hypothetical protein 0.0128 0.0503 0.05
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Schistosoma mansoni lamin 0.0194 0.0817 0.0815
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Loa Loa (eye worm) RGS-3 protein 0.0041 0.0083 0.0073
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Schistosoma mansoni organic anion transporter 0.0028 0.002 0.0017
Leishmania major trypanothione reductase 0.0047 0.0111 0.0351
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0028 0.002 0.0017
Echinococcus granulosus shaker cognate 0.0084 0.0289 0.0286
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0084 0.0289 0.0286
Trypanosoma brucei DNA polymerase IV, putative 0.0067 0.021 0.0722
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0014 0.0002
Plasmodium vivax DNA topoisomerase II, putative 0.0073 0.0234 0.1426
Loa Loa (eye worm) hypothetical protein 0.0223 0.0957 0.0948
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0124 0.0482 0.0472
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0356 0.1594 0.2843
Loa Loa (eye worm) hypothetical protein 0.0356 0.1594 0.1586
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0124 0.0482 0.1688
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0084 0.0289 0.0279
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0057 0.008
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0185 0.0776 0.4731
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.004 0.0079 0.0237
Echinococcus granulosus expressed protein 0.0802 0.3739 0.3737
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0057 0.0348
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0414 0.1874 0.1865
Echinococcus granulosus Nuclear hormone receptor HR96 0.0191 0.0802 0.0799
Loa Loa (eye worm) hypothetical protein 0.0124 0.0482 0.0472
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0223 0.0957 0.0948
Echinococcus multilocularis transient receptor potential cation channel 0.0084 0.0289 0.0286
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0124 0.0482 0.1668
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0124 0.0482 0.0479
Brugia malayi Importin beta-1 subunit 0.0088 0.0308 0.0298
Brugia malayi latrophilin 2 splice variant baaae 0.0176 0.0732 0.0723
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0124 0.0482 0.2578
Schistosoma mansoni hypothetical protein 0.1049 0.4928 0.4927
Loa Loa (eye worm) nuclear receptor NHR-67 0.0191 0.0802 0.0793
Schistosoma mansoni laminin gamma-3 chain 0.0052 0.0134 0.0131
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0356 0.1594 0.7573
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0233 0.0223
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0028 0.0019 0.0008
Schistosoma mansoni ryanodine receptor related 0.0084 0.0289 0.0286
Echinococcus granulosus voltage gated hydrogen channel 1 0.0084 0.0289 0.0286
Echinococcus granulosus calcium activated potassium channel 0.0084 0.0289 0.0286
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0075 0.0248 0.0835
Loa Loa (eye worm) hypothetical protein 0.0356 0.1594 0.1586
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0084 0.0289 0.0279
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0401 0.1904
Brugia malayi PAS domain containing protein 0.0102 0.0376 0.0366
Echinococcus granulosus transient receptor potential cation channel 0.0084 0.0289 0.0287
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0191 0.0802 0.0799
Echinococcus multilocularis voltage dependent calcium channel 0.0084 0.0289 0.0286
Onchocerca volvulus 0.0191 0.0802 0.1423
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0451 0.2055 0.2053
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0233 0.1105
Loa Loa (eye worm) hypothetical protein 0.0072 0.0233 0.0223
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0084 0.0289 0.176
Brugia malayi Nuclear hormone receptor-like 1 0.0223 0.0957 0.0948
Echinococcus multilocularis potassium large conductance calcium activated 0.0084 0.0289 0.0286
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0083 0.008
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0153 0.0621 0.0611
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0083 0.008
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0414 0.1874 0.1865
Loa Loa (eye worm) hypothetical protein 0.2104 1 1
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0083 0.008
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0041 0.0083 0.0395
Brugia malayi Nuclear hormone receptor-like 1 0.0414 0.1874 0.1865
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0105 0.0389 0.1338
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Echinococcus multilocularis lamin 0.0194 0.0817 0.0815
Trypanosoma cruzi DNA topoisomerase II, putative 0.0065 0.0199 0.0662
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0084 0.0289 0.0286
Schistosoma mansoni ran 0.0065 0.0196 0.0194
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0086 0.0299 0.1038
Loa Loa (eye worm) TOPoisomerase family member 0.0073 0.0234 0.0224
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0084 0.0289 0.0286
Brugia malayi Niemann-Pick C1 protein precursor 0.0311 0.1378 0.1369
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0084 0.0289 0.0279
Brugia malayi small heat shock protein 0.0675 0.313 0.3123
Echinococcus multilocularis sterol regulatory element binding protein 0.0269 0.118 0.1177
Brugia malayi cytochrome P450 0.0041 0.0083 0.0073
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0082 0.0277 0.0275
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0083 0.0073
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0124 0.0482 0.0479
Leishmania major DNA polymerase eta, putative 0.0037 0.0063 0.018
Loa Loa (eye worm) hypothetical protein 0.0072 0.0233 0.0223
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0414 0.1874 0.1871
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0034 0.0207
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0084 0.0289 0.0279
Onchocerca volvulus 0.0084 0.0289 0.05
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Brugia malayi Cytochrome P450 family protein 0.006 0.0176 0.0166
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0081 0.0079
Loa Loa (eye worm) CXXC zinc finger family protein 0.0118 0.0453 0.0444
Brugia malayi PXA domain containing protein 0.0041 0.0083 0.0073
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0233 0.0396
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0075 0.0248 0.1442
Echinococcus multilocularis transient receptor potential cation channel 0.0244 0.1058 0.1056
Echinococcus multilocularis hyperpolarization activated cyclic 0.0084 0.0289 0.0286
Brugia malayi nuclear receptor NHR-88 0.0191 0.0802 0.0793
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0191 0.0802 0.0799
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0034 0.0076
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0233 0.0804
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0156 0.0634 0.0631
Echinococcus granulosus transient receptor potential cation channel 0.0084 0.0289 0.0286
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0223 0.0957 0.0954
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Brugia malayi hypothetical protein 0.0084 0.0289 0.0279
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0214 0.0914 0.3204
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0083 0.008
Leishmania major cytochrome p450-like protein 0.0041 0.0083 0.025
Mycobacterium tuberculosis Conserved hypothetical protein 0.0322 0.1434 0.6811
Echinococcus multilocularis dnaJ subfamily B 0.1245 0.5869 0.5868
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0151 0.0613 0.0611
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0233 0.0396
Loa Loa (eye worm) inositol-1 0.0036 0.0059 0.0049
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0084 0.0289 0.0286
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0201 0.0668
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0147 0.0897
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0356 0.1594 0.7573
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0034 0.0031
Onchocerca volvulus 0.0148 0.0596 0.1052
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0612 0.2825 1
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0156 0.0634 0.0624
Brugia malayi EGF-like domain containing protein 0.0052 0.0134 0.0124
Echinococcus multilocularis voltage gated potassium channel 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.0356 0.1594 0.1586
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0026 0.001 0.0007
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0034 0.0031
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0084 0.0289 0.0286
Treponema pallidum sodium- and chloride- dependent transporter 0.0153 0.0621 0.3785
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0081 0.0497
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0414 0.1874 0.1865
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.021 0.0722
Echinococcus granulosus potassium large conductance calcium activated 0.0084 0.0289 0.0286
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0075 0.0248 0.0238
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.0427 0.0424
Schistosoma mansoni acetylcholinesterase 0.0356 0.1594 0.1592
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0089 0.0294
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0073 0.0234 0.0224
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0084 0.0289 0.0279
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0077 0.0256 0.0246
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0084 0.0289 0.0286
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.021 0.0722
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0084 0.0289 0.05
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0156 0.0634 0.1117
Echinococcus multilocularis acetylcholinesterase 0.2104 1 1
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0084 0.0289 0.1003
Schistosoma mansoni sodium-dependent amino acid transporter 0.0026 0.001 0.0007
Echinococcus granulosus voltage dependent calcium channel 0.0084 0.0289 0.0286
Echinococcus granulosus Solute carrier organic anion transporter family 0.0028 0.002 0.0017
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.033 0.1474 0.8982
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0083 0.008
Loa Loa (eye worm) TAR-binding protein 0.0194 0.0818 0.0809
Echinococcus granulosus two pore calcium channel protein 2 0.0084 0.0289 0.0286
Schistosoma mansoni tar DNA-binding protein 0.0194 0.0818 0.0816
Echinococcus multilocularis transfer RNA-Thr 0.035 0.1567 0.1565
Brugia malayi Transient-receptor-potential like protein 0.0084 0.0289 0.0279
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0414 0.1874 0.1865
Echinococcus multilocularis Niemann Pick C1 protein 0.0311 0.1378 0.1376
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0084 0.0289 0.0286
Echinococcus multilocularis protein dispatched 1 0.0288 0.127 0.1268
Trypanosoma cruzi importin beta-1 subunit, putative 0.0071 0.0228 0.0765
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0691
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Trypanosoma brucei DNA polymerase IV, putative 0.0067 0.021 0.0722
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0084 0.0289 0.0286
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0414 0.1874 0.1871
Schistosoma mansoni intermediate filament proteins 0.0194 0.0817 0.0815
Loa Loa (eye worm) solute carrier family 6 member 4 0.0153 0.0621 0.0611
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0151 0.0613 0.0611
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0414 0.1874 0.1871
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.0427 0.0424
Echinococcus granulosus tar DNA binding protein 0.0194 0.0818 0.0816
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0406 0.1836 0.1834
Entamoeba histolytica hypothetical protein 0.0041 0.0083 0.0197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0014 0.0002
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.001
Onchocerca volvulus 0.0028 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0356 0.1594 0.1586
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0094 0.0335 0.0332
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0073
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Loa Loa (eye worm) hypothetical protein 0.0153 0.0621 0.0611
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.2104 1 1
Toxoplasma gondii DNA topoisomerase 2, putative 0.0073 0.0234 0.1426
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0084 0.0289 0.0279
Echinococcus granulosus protein prenyltransferase alpha subunit 0.004 0.0079 0.0077
Mycobacterium leprae putative cytochrome p450 0.0185 0.0776 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0065 0.0196 0.0653
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0414 0.1874 0.1871
Schistosoma mansoni organic anion transporter 0.0028 0.002 0.0017
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0083 0.008
Plasmodium vivax amine transporter, putative 0.0026 0.001 0.0062
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0084 0.0289 0.0286
Leishmania major hypothetical protein, conserved 0.0084 0.0289 0.0982
Brugia malayi cytoplasmic intermediate filament protein 0.0104 0.0385 0.0375
Brugia malayi hypothetical protein 0.0054 0.0147 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0002
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0084 0.0289 0.0286
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0191 0.0802 0.0799
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0156 0.0634 0.3864
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0028 0.0019 0.0016
Schistosoma mansoni z-protein (S1r protein) 0.0041 0.0083 0.008
Echinococcus multilocularis protein patched 0.0269 0.118 0.1177
Brugia malayi nuclear receptor NHR-67 0.0191 0.0802 0.0793
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0169 0.0159
Schistosoma mansoni single-minded 0.0102 0.0376 0.0373
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0414 0.1874 0.3348
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0084 0.0289 0.0496
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.004 0.0079 0.0484
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0075 0.0248 0.0835
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.033 0.1474 0.1471
Trypanosoma cruzi cytochrome P450, putative 0.0059 0.0169 0.0554
Brugia malayi steroid hormone receptor 0.0414 0.1874 0.1865
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0034 0.0031
Echinococcus multilocularis tar DNA binding protein 0.0194 0.0818 0.0816
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0156 0.0634 0.0631
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0041 0.0083 0.0073
Schistosoma mansoni hypothetical protein 0.0939 0.4397 0.4395
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0124 0.0482 0.0843
Echinococcus granulosus ubiquitin specific protease 41 0.0124 0.0482 0.0479
Mycobacterium tuberculosis Carboxylesterase LipT 0.0356 0.1594 0.7573
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0086 0.0299 0.1017
Echinococcus granulosus potassium voltage gated channel protein 0.0084 0.0289 0.0286
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0813 0.3794 0.3793
Echinococcus granulosus cpg binding protein 0.0125 0.0486 0.0483
Mycobacterium leprae Conserved hypothetical protein 0.0041 0.0083 0.0922
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0111 0.0351
Brugia malayi laminin alpha chain 0.0052 0.0134 0.0124
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0057 0.0159 0.0522
Brugia malayi hypothetical protein 0.0148 0.0596 0.0586
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0365 0.1641 1
Echinococcus granulosus sodium leak channel non selective protein 0.0084 0.0289 0.0286
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0035 0.0053 0.005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0414 0.1874 0.1865
Loa Loa (eye worm) hypothetical protein 0.0176 0.0732 0.0723
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0414 0.1874 0.1865
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Onchocerca volvulus 0.0414 0.1874 0.3348
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0057 0.008
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0084 0.0289 0.0286
Loa Loa (eye worm) intermediate filament protein 0.0194 0.0817 0.0808
Mycobacterium tuberculosis Conserved protein 0.0072 0.0233 0.1105
Trichomonas vaginalis ran, putative 0.0065 0.0196 0.033
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0233 0.1105
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Brugia malayi Nuclear hormone receptor E75 0.0191 0.0802 0.0793
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0194 0.0817 0.0808
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0365 0.1641 0.2926
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0156 0.0634 0.0631
Loa Loa (eye worm) hypothetical protein 0.033 0.1474 0.1465
Brugia malayi Carboxylesterase family protein 0.2104 1 1
Loa Loa (eye worm) transcription factor SMAD2 0.0235 0.1014 0.1005
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0084 0.0289 0.0982
Echinococcus multilocularis pikachurin 0.0052 0.0134 0.0131
Echinococcus multilocularis two pore calcium channel protein 1 0.0084 0.0289 0.0286
Leishmania major DNA polymerase eta, putative 0.0062 0.0184 0.0609
Brugia malayi Nuclear hormone receptor-like 1 0.0223 0.0957 0.0948
Schistosoma mansoni nuclear receptor nhr-48 0.0191 0.0802 0.0799
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0084 0.0289 0.0279
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0124 0.0482 0.3216
Entamoeba histolytica hypothetical protein 0.0041 0.0083 0.0197
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0356 0.1594 0.1592
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0691
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0075 0.0248 0.0835
Echinococcus multilocularis carboxylesterase 5A 0.2104 1 1
Schistosoma mansoni alpha-glucosidase 0.0139 0.0552 0.0549
Echinococcus multilocularis transfer RNA-Lys 0.0075 0.0248 0.0245
Brugia malayi Steroid receptor seven-up type 2 0.0414 0.1874 0.1865
Echinococcus granulosus neuroligin 0.0356 0.1594 0.1592
Echinococcus multilocularis hyperpolarization activated cyclic 0.0084 0.0289 0.0286
Loa Loa (eye worm) hypothetical protein 0.035 0.1567 0.1558
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0026 0.001 0.0062
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0084 0.0289 0.0286
Echinococcus granulosus microtubule associated protein 2 0.2084 0.99 0.99
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0462 0.2105 1
Brugia malayi hypothetical protein 0.0342 0.153 0.1522
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.002 0.001
Loa Loa (eye worm) hypothetical protein 0.2104 1 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0414 0.1874 0.1865
Onchocerca volvulus 0.0077 0.0254 0.0438
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0691
Loa Loa (eye worm) hypothetical protein 0.0414 0.1874 0.1865
Brugia malayi Pre-SET motif family protein 0.0151 0.0613 0.0604
Echinococcus granulosus BC026374 protein S09 family 0.0356 0.1594 0.1592
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0155 0.063 0.111
Brugia malayi CHE-14 protein 0.0269 0.118 0.1171
Schistosoma mansoni vesicular amine transporter 0.0084 0.0289 0.0286
Brugia malayi nuclear hormone receptor 0.0414 0.1874 0.1865
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0365 0.1641 1
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Toxoplasma gondii ABC1 family protein 0.0072 0.0233 0.1418
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0041 0.0083 0.0395
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0065 0.0196 0.0749
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0034 0.0024
Loa Loa (eye worm) histone methyltransferase 0.0042 0.0087 0.0077
Echinococcus multilocularis neuroligin 0.0356 0.1594 0.1592
Echinococcus granulosus lamin 0.0194 0.0817 0.0815
Loa Loa (eye worm) hypothetical protein 0.0356 0.1594 0.1586
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0458 0.2177
Loa Loa (eye worm) hypothetical protein 0.0356 0.1594 0.1586
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0124 0.0482 0.0479
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0036 0.006 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.021 0.0722
Echinococcus granulosus Regulator of G protein signaling 20 0.0041 0.0083 0.008
Echinococcus multilocularis sodium leak channel non selective protein 0.0084 0.0289 0.0286
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0414 0.1874 0.1871
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0214 0.0914 0.322
Leishmania major hypothetical protein, conserved 0.0072 0.0233 0.0782
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0414 0.1874 0.1865
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0612 0.2825 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0075 0.0248 0.1176
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0214 0.0914 0.5569
Echinococcus granulosus sodium and chloride dependent glycine 0.0026 0.001 0.0007
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0155 0.063 0.111
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0414 0.1874 0.1871
Brugia malayi nuclear receptor RXR 0.0191 0.0802 0.0793
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Echinococcus granulosus transient receptor potential cation channel 0.0244 0.1058 0.1055
Schistosoma mansoni hypothetical protein 0.0082 0.0277 0.0275
Echinococcus multilocularis expressed conserved protein 0.0292 0.1287 0.1285
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0026 0.001 0.0062
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0084 0.0289 0.0286
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0185 0.0776 0.3687
Echinococcus granulosus nuclear receptor nhr 48 0.0191 0.0802 0.0799
Leishmania major DNA polymerase kappa, putative 0.0044 0.0097 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0002
Schistosoma mansoni nuclear receptor 0.0191 0.0802 0.0799
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0057 0.0159 0.0522
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0083 0.008
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0073
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0214 0.0914 0.434
Toxoplasma gondii transporter, cation channel family protein 0.0084 0.0289 0.176
Mycobacterium tuberculosis Probable reductase 0.0107 0.0401 0.1904
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0041 0.0083 0.0395
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.004 0.0079 0.0261
Schistosoma mansoni steroid hormone receptor ad4bp 0.0414 0.1874 0.1871
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.004 0.0079 0.0077
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0084 0.0289 0.0286
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0185 0.0776 0.4731
Schistosoma mansoni lamin 0.0194 0.0817 0.0815
Brugia malayi hypothetical protein 0.0113 0.0427 0.0417
Echinococcus multilocularis sodium and chloride dependent glycine 0.0026 0.001 0.0007
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0191 0.0802 0.0799
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0084 0.0289 0.0286
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0233 0.023
Brugia malayi Cytochrome P450 family protein 0.0059 0.0169 0.0159
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0041 0.0083 0.0127
Brugia malayi Carboxylesterase family protein 0.0356 0.1594 0.1586
Onchocerca volvulus 0.004 0.0079 0.0124
Schistosoma mansoni two-pore calcium channel 0.0084 0.0289 0.0286
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Echinococcus granulosus transcription factor Dp 1 0.0045 0.01 0.0097
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0035 0.0053 0.005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0197 0.0832 0.0829
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.004 0.0079 0.0237
Brugia malayi hypoxia-induced factor 1 0.0316 0.1403 0.1394
Schistosoma mansoni tar DNA-binding protein 0.0194 0.0818 0.0816
Schistosoma mansoni alpha glucosidase 0.0036 0.0057 0.0054
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0014 0.0002
Schistosoma mansoni thyroid hormone receptor 0.0546 0.251 0.2508
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0185 0.0776 0.4731
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0365 0.1641 1
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0289 0.0286
Toxoplasma gondii transporter, cation channel family protein 0.0084 0.0289 0.176
Schistosoma mansoni hypothetical protein 0.0128 0.0503 0.05
Echinococcus multilocularis microtubule associated protein 2 0.2084 0.99 0.99
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0041 0.0083 0.0395
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0083 0.008
Brugia malayi RNA recognition motif domain containing protein 0.0194 0.0818 0.0809
Loa Loa (eye worm) CYP4Cod1 0.0059 0.0169 0.0159
Loa Loa (eye worm) hypothetical protein 0.0084 0.0289 0.0279
Loa Loa (eye worm) hypothetical protein 0.0191 0.0802 0.0793
Loa Loa (eye worm) voltage-gated potassium channel 0.0084 0.0289 0.0279
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0073
Loa Loa (eye worm) cytochrome P450 family protein 0.006 0.0176 0.0166
Schistosoma mansoni hypothetical protein 0.0128 0.0503 0.05
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.004 0.0079 0.0261
Echinococcus multilocularis FTZ F1 alpha 0.0414 0.1874 0.1871
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0083 0.0127
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0065 0.0196 0.0186
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0041 0.0083 0.0395
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0084 0.0289 0.0286
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0233 0.2882
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0232 0.0229
Toxoplasma gondii hypothetical protein 0.0026 0.001 0.0062
Brugia malayi olfactory channel protein osm-9 0.0084 0.0289 0.0279
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0311 0.1378 1
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0057 0.0054
Schistosoma mansoni ap endonuclease 0.0075 0.0248 0.0245
Schistosoma mansoni hypothetical protein 0.0176 0.0732 0.073
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0084 0.0289 0.0286
Onchocerca volvulus 0.0093 0.0333 0.058
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0086 0.0299 0.1017
Onchocerca volvulus 0.0356 0.1594 0.2846
Echinococcus multilocularis sodium and chloride dependent glycine 0.0026 0.001 0.0007

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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