Detailed information for compound 1695200

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 708.919 | Formula: C39H64O11
  • H donors: 9 H acceptors: 10 LogP: 4.83 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 3
  • SMILES: O[C@H]1CC[C@H](C)[C@@H](OC(=O)/C=C/C=C/C=C/C=C/C=C/C=C\C[C@H](C[C@@H](C[C@@H](C[C@@H](C[C@H](C[C@@H](C[C@H](C[C@H](C1)O)O)O)O)O)O)O)O)C(C)C
  • InChi: 1S/C39H64O11/c1-27(2)39-28(3)17-18-30(41)20-32(43)22-34(45)24-36(47)26-37(48)25-35(46)23-33(44)21-31(42)19-29(40)15-13-11-9-7-5-4-6-8-10-12-14-16-38(49)50-39/h4-14,16,27-37,39-48H,15,17-26H2,1-3H3/b5-4+,8-6+,9-7+,12-10+,13-11-,16-14+/t28-,29+,30-,31-,32-,33-,34-,35-,36+,37+,39-/m0/s1
  • InChiKey: OLPMWTXTIALTJI-OIJGFXDKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Echinococcus multilocularis ephrin type A receptor 4 A 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0028 0.0162 0.015
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0233 0.022
Loa Loa (eye worm) TK/EPH protein kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0162 0.015
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0115 0.0126
Trichomonas vaginalis AGC family protein kinase 0.1045 1 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.0016 0.004 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.1045 1 1
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Schistosoma mansoni tyrosine protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Onchocerca volvulus 0.0032 0.0194 1
Brugia malayi Furin-like cysteine rich region family protein 0.0028 0.0162 0.015
Loa Loa (eye worm) hypothetical protein 0.0301 0.2801 0.2791
Echinococcus granulosus serine:threonine protein kinase 12 B 0.1045 1 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.0183 0.0021
Echinococcus granulosus integrin linked protein kinase 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase Fyn 0.0035 0.0226 0.0213
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0032 0.0194 0.0182
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0366 0.0354
Schistosoma mansoni protein tyrosine kinase 0.0028 0.0162 0.015
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0037 0.0245 0.0232
Echinococcus granulosus activated cdc42 kinase 1 0.0028 0.0162 0.015
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0226 0.0213
Entamoeba histolytica serine/threonine kinase, putative 0.0028 0.0162 0.0159
Loa Loa (eye worm) TK protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica hypothetical protein 0.0028 0.0162 0.0159
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0028 0.0162 0.015
Loa Loa (eye worm) TK protein kinase 0.0028 0.0162 0.015
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0035 0.0226 0.0213
Onchocerca volvulus 0.0032 0.0194 1
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Schistosoma mansoni cell adhesion molecule 0.0301 0.2801 0.2791
Schistosoma mansoni hypothetical protein 0.0016 0.004 0.0027
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0028 0.0162 0.8323
Echinococcus granulosus twitchin 0.0309 0.2883 0.2874
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Entamoeba histolytica serine/threonine kinase, putative 0.0028 0.0162 0.0159
Echinococcus granulosus fibroblast growth factor receptor 4 0.0028 0.0162 0.015
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0033 0.0204 0.0191
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0028 0.0162 0.015
Trypanosoma brucei Pseudokinase, putative 0.0028 0.0162 0.0162
Echinococcus multilocularis epidermal growth factor receptor 0.0028 0.0162 0.015
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Brugia malayi Immunoglobulin I-set domain containing protein 0.0329 0.3074 0.3065
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Leishmania major cytochrome p450-like protein 0.0023 0.0115 0.0102
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0028 0.0162 0.015
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0115 0.0075
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Trichomonas vaginalis AGC family protein kinase 0.1045 1 1
Entamoeba histolytica receptor protein kinase, putative 0.0028 0.0162 0.0159
Echinococcus multilocularis c src tyrosine kinase 0.0035 0.0226 0.0213
Echinococcus granulosus retinal guanylyl cyclase 2 0.0028 0.0162 0.015
Echinococcus multilocularis Immunoglobulin 0.0301 0.2801 0.2791
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Loa Loa (eye worm) hypothetical protein 0.0301 0.2801 0.2791
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.1045 1 1
Schistosoma mansoni ephrin receptor 0.0028 0.0162 0.015
Schistosoma mansoni protein kinase 0.0028 0.0162 0.015
Leishmania major protein kinase, putative 0.0037 0.0245 0.0232
Schistosoma mansoni hypothetical protein 0.0028 0.0162 0.015
Brugia malayi hypothetical protein 0.0028 0.0162 0.015
Echinococcus granulosus receptor type guanylyl cyclase 0.0028 0.0162 0.015
Brugia malayi integrin-linked kinase 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0028 0.0162 0.0159
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0115 0.0075
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Echinococcus multilocularis tyrosine protein kinase pr2 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase, putative 0.1045 1 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0033 0.0204 0.0191
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0115 0.0115
Onchocerca volvulus 0.0028 0.0162 0.8323
Echinococcus granulosus tyrosine protein kinase Lyn 0.0043 0.0308 0.0296
Echinococcus multilocularis tyrosine protein kinase csk 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Mycobacterium leprae Isocitrate lyase 0.0294 0.2735 0.4552
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Trypanosoma brucei Flagellum attachment zone protein 20 0.0028 0.0162 0.0162
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Loa Loa (eye worm) AUR protein kinase 0.1045 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Entamoeba histolytica hypothetical protein 0.0028 0.0162 0.0159
Echinococcus multilocularis tyrosine kinase 0.0028 0.0162 0.015
Echinococcus multilocularis protein KINase family member (kin 25) 0.0028 0.0162 0.015
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/ABL protein kinase 0.0032 0.0194 0.0182
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0035 0.0226 0.0213
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0035 0.0226 0.0213
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0028 0.0162 0.015
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0233 0.022
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0194 0.0182
Trypanosoma brucei protein kinase, putative 0.0037 0.0245 0.0245
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0301 0.2801 0.2791
Entamoeba histolytica receptor protein kinase, putative 0.0028 0.0162 0.0159
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.1045 1 1
Echinococcus multilocularis tyrosine protein kinase shark 0.0032 0.0194 0.0182
Echinococcus granulosus insulin receptor 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0028 0.0162 0.015
Brugia malayi SH2 domain containing protein 0.0032 0.0194 0.0182
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0037 0.0245 0.0245
Entamoeba histolytica hypothetical protein 0.0028 0.0162 0.0159
Echinococcus granulosus aurora kinase A 0.1045 1 1
Schistosoma mansoni protein kinase 0.1045 1 1
Onchocerca volvulus 0.0028 0.0162 0.8323
Plasmodium falciparum protein kinase, putative 0.0037 0.0245 0.0232
Plasmodium vivax serine/threonine protein kinase 6, putative 0.1045 1 1
Onchocerca volvulus 0.0028 0.0162 0.8323
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0301 0.2801 0.2791
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0035 0.0226 0.0213
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Entamoeba histolytica hypothetical protein 0.0028 0.0162 0.0159
Onchocerca volvulus 0.0032 0.0194 1
Onchocerca volvulus 0.0028 0.0162 0.8323
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0028 0.0162 0.015
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0032 0.0194 0.0191
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0037 0.0245 0.0206
Loa Loa (eye worm) hypothetical protein 0.0301 0.2801 0.2791
Echinococcus multilocularis protein kinase 0.0028 0.0162 0.015
Echinococcus multilocularis activin receptor type 0.0037 0.0245 0.0232
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Onchocerca volvulus 0.0028 0.0162 0.8323
Brugia malayi Cytochrome P450 family protein 0.0023 0.0115 0.0102
Brugia malayi Guanylyl cyclase protein 23 0.0028 0.0162 0.015
Brugia malayi bone morphogenetic protein type 1 receptor 0.0028 0.0162 0.015
Loa Loa (eye worm) SRC-1 0.0035 0.0226 0.0213
Echinococcus granulosus natriuretic peptide receptor 1 0.0028 0.0162 0.015
Echinococcus granulosus epidermal growth factor receptor 0.0028 0.0162 0.015
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.0183 0.0021
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase csk 0.0028 0.0162 0.015
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0028 0.0162 0.8323
Leishmania major protein kinase, putative 0.1045 1 1
Entamoeba histolytica hypothetical protein 0.0028 0.0162 0.0159
Echinococcus multilocularis tyrosine protein kinase csk 0.0028 0.0162 0.015
Entamoeba histolytica serine/threonine kinase, putative 0.0028 0.0162 0.0159
Echinococcus granulosus tyrosine protein kinase pr2 0.0028 0.0162 0.015
Schistosoma mansoni protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase , putative 0.1045 1 1
Leishmania major hypothetical protein, conserved 0.0028 0.0162 0.015
Loa Loa (eye worm) TK protein kinase 0.0028 0.0162 0.015
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0035 0.0226 0.0213
Leishmania major cytochrome p450-like protein 0.0016 0.004 0.0027
Mycobacterium tuberculosis Isocitrate lyase Icl (isocitrase) (isocitratase) 0.0627 0.5961 1
Entamoeba histolytica cysteine surface protein, putative 0.0028 0.0162 0.0159
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0226 0.0213
Entamoeba histolytica ankyrin repeat protein 0.0028 0.0162 0.0159
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0194 0.0182
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Trypanosoma cruzi protein kinase, putative 0.0028 0.0162 0.0123
Schistosoma mansoni protein kinase 0.0037 0.0245 0.0232
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0033 0.0204 0.0191
Echinococcus granulosus tyrosine protein kinase Fyn 0.0035 0.0226 0.0213
Mycobacterium tuberculosis Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) 0.0627 0.5961 1
Entamoeba histolytica hypothetical protein 0.0028 0.0162 0.0159
Entamoeba histolytica hypothetical protein 0.0028 0.0162 0.0159
Echinococcus multilocularis activated cdc42 kinase 1 0.0028 0.0162 0.015
Echinococcus multilocularis tyrosine protein kinase csk 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/CSK protein kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0162 0.015
Echinococcus multilocularis FL cytokine receptor 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase ABL1 0.0032 0.0194 0.0182
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0162 0.015
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) TK protein kinase 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase Src64B 0.0035 0.0226 0.0213
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Echinococcus multilocularis aurora kinase A 0.1045 1 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Echinococcus multilocularis protein tyrosine kinase 0.0028 0.0162 0.015
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.1045 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Loa Loa (eye worm) hypothetical protein 0.0301 0.2801 0.2791
Brugia malayi SH2 domain containing protein 0.0032 0.0194 0.0182
Brugia malayi protein-tyrosine kinase 0.0032 0.0194 0.0182
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0035 0.0226 0.0213
Loa Loa (eye worm) AUR protein kinase 0.1045 1 1
Entamoeba histolytica hypothetical protein 0.0028 0.0162 0.0159
Loa Loa (eye worm) hypothetical protein 0.0032 0.0194 0.0182
Onchocerca volvulus 0.0028 0.0162 0.8323
Schistosoma mansoni tyrosine kinase 0.0035 0.0226 0.0213
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Schistosoma mansoni protein kinase 0.0028 0.0162 0.015
Plasmodium falciparum serine/threonine protein kinase, putative 0.1045 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0033 0.0204 0.0191
Echinococcus granulosus Immunoglobulin 0.0301 0.2801 0.2791
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Schistosoma mansoni protein kinase 0.0037 0.0245 0.0232
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Brugia malayi hypothetical protein 0.0032 0.0194 0.0182
Trypanosoma cruzi protein kinase, putative 0.0028 0.0162 0.0123
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0037 0.0245 0.0206
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0115 0.0102
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0162 0.015
Schistosoma mansoni protein kinase 0.0037 0.0245 0.0232
Schistosoma mansoni tyrosine kinase 0.0035 0.0226 0.0213
Loa Loa (eye worm) TK protein kinase 0.0028 0.0162 0.015
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0162 0.015
Echinococcus multilocularis Immunoglobulin 0.0301 0.2801 0.2791
Brugia malayi hypothetical protein 0.0301 0.2801 0.2791
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0035 0.0226 0.0213
Echinococcus multilocularis kinase suppressor of Ras 1 0.0028 0.0162 0.015
Schistosoma mansoni protein kinase 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0032 0.0194 0.0182
Brugia malayi ephrin receptor 1 precursor 0.0028 0.0162 0.015
Schistosoma mansoni serine/threonine RGC 0.0028 0.0162 0.015
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0028 0.0162 0.015
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Echinococcus granulosus activin receptor type 0.0037 0.0245 0.0232
Loa Loa (eye worm) TK/ACK protein kinase 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Echinococcus multilocularis roundabout 2 0.0301 0.2801 0.2791
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0028 0.0162 0.015
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0028 0.0162 0.015
Echinococcus granulosus ephrin type A receptor 4 A 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0035 0.0226 0.0213
Echinococcus granulosus tyrosine kinase 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Brugia malayi Tyrosine-protein kinase PR2 0.0028 0.0162 0.015
Onchocerca volvulus 0.0032 0.0194 1
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0037 0.0245 0.0232
Loa Loa (eye worm) TK/DDR protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.1045 1 1
Loa Loa (eye worm) TK protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica tyrosin kinase, putative 0.0028 0.0162 0.0159
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0035 0.0226 0.0213
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0032 0.0194 0.0182
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Brugia malayi Cytochrome P450 family protein 0.0016 0.004 0.0027
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Echinococcus granulosus neuroglian 0.0301 0.2801 0.2791
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0028 0.0162 0.015
Entamoeba histolytica serine/threonine kinase, putative 0.0028 0.0162 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0193 0.0181
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Mycobacterium ulcerans isocitrate lyase AceAb 0.0627 0.5961 1
Toxoplasma gondii aurora kinase 0.1045 1 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0032 0.0194 0.0182
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0301 0.2801 0.2791
Echinococcus granulosus tyrosine protein kinase csk 0.0028 0.0162 0.015
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0028 0.0162 0.0162
Entamoeba histolytica tyrosin kinase, putative 0.0028 0.0162 0.0159
Brugia malayi Immunoglobulin I-set domain containing protein 0.0301 0.2801 0.2791
Loa Loa (eye worm) protein kinase domain-containing protein 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) TK protein kinase 0.0032 0.0194 0.0182
Brugia malayi cytochrome P450 0.0016 0.004 0.0027
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0162 0.015
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0301 0.2801 0.2791
Echinococcus multilocularis receptor type guanylyl cyclase 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/Met protein kinase 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0035 0.0226 0.0213
Entamoeba histolytica tyrosin kinase, putative 0.0028 0.0162 0.0159
Loa Loa (eye worm) TK protein kinase 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Schistosoma mansoni protein kinase 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Entamoeba histolytica serine/threonine kinase, putative 0.0028 0.0162 0.0159
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase Blk 0.0032 0.0194 0.0182
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0194 0.0182
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0032 0.0194 0.0182
Loa Loa (eye worm) TK protein kinase 0.0028 0.0162 0.015
Leishmania major cytochrome p450-like protein 0.0016 0.004 0.0027
Echinococcus granulosus defective proboscis extension response 0.0301 0.2801 0.2791
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase Fyn 0.0035 0.0226 0.0213
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0032 0.0194 0.0182
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0028 0.0162 0.0159
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Plasmodium falciparum tyrosine kinase-like protein 0.0028 0.0162 0.015
Onchocerca volvulus 0.0028 0.0162 0.8323
Loa Loa (eye worm) hypothetical protein 0.0301 0.2801 0.2791
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Echinococcus granulosus epidermal growth factor receptor 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0194 0.0182
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0028 0.0162 0.015
Echinococcus multilocularis raf serine:threonine protein kinase 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Plasmodium falciparum protein kinase, putative 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Giardia lamblia Aurora kinase 0.1045 1 1
Echinococcus granulosus protein tyrosine kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) serine/threonine protein kinase 0.0028 0.0162 0.015
Onchocerca volvulus 0.0032 0.0194 1
Toxoplasma gondii protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica hypothetical protein, conserved 0.0028 0.0162 0.0159
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Echinococcus granulosus tyrosine protein kinase HCK 0.0028 0.0162 0.015
Echinococcus multilocularis insulin receptor 0.0028 0.0162 0.015
Echinococcus granulosus c src tyrosine kinase 0.0035 0.0226 0.0213
Loa Loa (eye worm) AUR protein kinase 0.1045 1 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0032 0.0194 0.0182
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0329 0.3074 0.3065
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0028 0.0162 0.015
Echinococcus multilocularis tyrosine protein kinase Abl 0.0035 0.0226 0.0213
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0037 0.0245 0.0232
Brugia malayi Fibronectin type III domain containing protein 0.0301 0.2801 0.2791
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0162 0.015
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0028 0.0162 0.015
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/ROR protein kinase 0.0028 0.0162 0.015
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0028 0.0162 0.015
Schistosoma mansoni nephrin 0.0301 0.2801 0.2791
Schistosoma mansoni tyrosine kinase 0.0035 0.0226 0.0213
Echinococcus multilocularis 0.0016 0.004 0.0027
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Brugia malayi serine/threonine kinase 12 0.1045 1 1
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0032 0.0194 0.0182
Echinococcus multilocularis tyrosine protein kinase Srms 0.0032 0.0194 0.0182
Toxoplasma gondii STE kinase 0.0028 0.0162 0.015
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Entamoeba histolytica tyrosin kinase, putative 0.0028 0.0162 0.0159
Echinococcus multilocularis protein kinase 0.0028 0.0162 0.015
Echinococcus multilocularis tyrosine protein kinase 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0032 0.0194 0.0182
Brugia malayi C-terminal src kinase protein 1 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase Srms 0.0032 0.0194 0.0182
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0035 0.0226 0.0213
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Schistosoma mansoni ephrin receptor 0.0028 0.0162 0.015
Entamoeba histolytica ankyrin repeat protein 0.0028 0.0162 0.0159
Schistosoma mansoni cytochrome P450 0.0016 0.004 0.0027
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Loa Loa (eye worm) hypothetical protein 0.0301 0.2801 0.2791
Entamoeba histolytica serine/threonine kinase, putative 0.0028 0.0162 0.0159
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/FAK protein kinase 0.0028 0.0162 0.015
Trichomonas vaginalis AGC family protein kinase 0.1045 1 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0028 0.0162 0.015
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0028 0.0162 0.015
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Entamoeba histolytica hypothetical protein 0.0028 0.0162 0.0159
Echinococcus granulosus tyrosine kinase 0.0032 0.0194 0.0182
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0035 0.0226 0.0213
Brugia malayi SRC-1 0.0035 0.0226 0.0213
Schistosoma mansoni protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Echinococcus multilocularis epidermal growth factor receptor 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0032 0.0194 0.0182
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0162 0.015
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0516 0.488 0.4874
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0194 0.0182
Mycobacterium ulcerans isocitrate lyase Icl 0.0627 0.5961 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0035 0.0226 0.0213
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase domain containing protein 0.0037 0.0245 0.0242
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0028 0.0162 0.015
Schistosoma mansoni protein kinase 0.0028 0.0162 0.015
Trypanosoma brucei aurora B kinase 0.1045 1 1
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0194 0.0182
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0194 0.0182
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Schistosoma mansoni tyrosine kinase 0.0032 0.0194 0.0182
Onchocerca volvulus 0.0028 0.0162 0.8323
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Entamoeba histolytica hypothetical protein 0.0028 0.0162 0.0159
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0028 0.0162 0.015
Brugia malayi Cytochrome P450 family protein 0.0049 0.0366 0.0354
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Echinococcus granulosus tyrosine protein kinase shark 0.0032 0.0194 0.0182
Loa Loa (eye worm) TK/FER protein kinase 0.0028 0.0162 0.015
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Echinococcus multilocularis tyrosine protein kinase HCK 0.0028 0.0162 0.015
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0028 0.0162 0.0159
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0028 0.0162 0.015
Entamoeba histolytica tyrosine kinase, putative 0.0028 0.0162 0.0159
Onchocerca volvulus 0.0028 0.0162 0.8323
Echinococcus granulosus retinal guanylyl cyclase 2 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/RYK protein kinase 0.0028 0.0162 0.015
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0028 0.0162 0.015
Echinococcus granulosus cytochrome P450 2K1 0.0016 0.004 0.0027
Echinococcus multilocularis integrin linked protein kinase 0.0028 0.0162 0.015
Echinococcus multilocularis neuroglian 0.0301 0.2801 0.2791
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0016 0.004 0.0027
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0194 0.0182
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Brugia malayi Receptor family ligand binding region containing protein 0.0028 0.0162 0.015
Entamoeba histolytica hypothetical protein 0.0028 0.0162 0.0159
Entamoeba histolytica protein kinase, putative 0.1045 1 1
Loa Loa (eye worm) TK/EGFR protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Loa Loa (eye worm) TK/INSR protein kinase 0.0028 0.0162 0.015
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0035 0.0226 0.0213
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Echinococcus granulosus tyrosine kinase 0.0032 0.0194 0.0182
Echinococcus granulosus tyrosine protein kinase 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Echinococcus multilocularis transfer RNA-Thr 0.0028 0.0162 0.015
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0028 0.0162 0.015
Brugia malayi serine/threonine-protein kinase 6 0.1045 1 1
Echinococcus granulosus raf serine:threonine protein kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) hypothetical protein 0.0301 0.2801 0.2791
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase domain containing protein 0.1045 1 1
Echinococcus granulosus tyrosine protein kinase csk 0.0028 0.0162 0.015
Leishmania major protein kinase, putative 0.0028 0.0162 0.015
Loa Loa (eye worm) cytochrome P450 0.0016 0.004 0.0027
Toxoplasma gondii protein kinase domain-containing protein 0.0028 0.0162 0.015
Echinococcus multilocularis tyrosine kinase 0.0032 0.0194 0.0182
Echinococcus multilocularis heat shock protein 70 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Brugia malayi hypothetical protein 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0194 0.0182
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0016 0.004 0.004
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0115 0.0102
Echinococcus granulosus activated cdc42 kinase 1 0.0028 0.0162 0.015
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0032 0.0194 0.0182
Echinococcus multilocularis natriuretic peptide receptor 1 0.0028 0.0162 0.015
Schistosoma mansoni protein kinase 0.0028 0.0162 0.015
Echinococcus granulosus roundabout 2 0.0301 0.2801 0.2791
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) TK/ALK protein kinase 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Schistosoma mansoni tyrosine kinase 0.0028 0.0162 0.015
Loa Loa (eye worm) hypothetical protein 0.0301 0.2801 0.2791
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Trypanosoma cruzi aurora B kinase, putative 0.1045 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Trichomonas vaginalis AGC family protein kinase 0.1045 1 1
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0115 0.0102
Brugia malayi Raf kinase 0.0028 0.0162 0.015
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Mycobacterium leprae PROBABLE ISOCITRATE LYASE AceA (ISOCITRASE) (ISOCITRATASE) (ICL) 0.0627 0.5961 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0028 0.0162 0.015
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Loa Loa (eye worm) hypothetical protein 0.0301 0.2801 0.2791
Brugia malayi Cytochrome P450 family protein 0.0023 0.0115 0.0102
Onchocerca volvulus Tyrosine kinase homolog 0.0028 0.0162 0.8323
Echinococcus multilocularis tyrosine protein kinase Blk 0.0032 0.0194 0.0182
Echinococcus granulosus kinase suppressor of Ras 1 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Plasmodium falciparum tyrosine kinase-like protein 0.0028 0.0162 0.015
Onchocerca volvulus 0.0032 0.0194 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.0162 0.0159
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0028 0.0162 0.0159
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.015
Loa Loa (eye worm) TK protein kinase 0.0028 0.0162 0.015
Schistosoma mansoni vesicular amine transporter 0.0303 0.2821 0.2812
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0194 0.0182
Brugia malayi Protein kinase domain containing protein 0.0028 0.0162 0.015
Mycobacterium tuberculosis Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) 0.0627 0.5961 1
Plasmodium falciparum protein kinase, putative 0.0028 0.0162 0.015
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0028 0.0162 0.015
Echinococcus granulosus protein kinase 0.0028 0.0162 0.015
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0035 0.0226 0.0213
Entamoeba histolytica protein kinase, putative 0.0028 0.0162 0.0159
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0162 0.015
Echinococcus granulosus retinal guanylyl cyclase 2 0.0028 0.0162 0.015

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Antibacterial activity against Escherichia coli ATCC 35270 ChEMBL. 22574670
Activity (functional) Antifungal activity against Candida albicans ATCC 10231 after 48 to 72 hrs ChEMBL. 22574670

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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