Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0057 | 0.0416 | 1 | |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.006 | 0.0439 | 0.3369 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0005 | 0.0014 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0067 | 0.0516 | 0.8644 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0067 | 0.0516 | 0.663 |
Loa Loa (eye worm) | glutathione reductase | 0.0055 | 0.0389 | 0.1236 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0191 | 0.099 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0068 | 0.0534 | 0.2772 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0139 | 0.1303 | 1 |
Plasmodium vivax | vivapain-2 | 0.0019 | 0.0005 | 0.0058 |
Leishmania major | cysteine peptidase A (CPA) | 0.0019 | 0.0005 | 0.0076 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0139 | 0.1303 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0032 | 0.0144 | 0.0447 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0068 | 0.0534 | 0.132 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0005 | 0.0014 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0038 | 0.021 | 0.1611 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0652 | 0.2081 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.0005 | 0.0005 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0032 | 0.0144 | 0.0355 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.0259 | 0.1343 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0043 | 0.0259 | 0.0259 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Schistosoma mansoni | survival motor neuron protein | 0.0056 | 0.0401 | 0.2081 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0032 | 0.0144 | 0.0144 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0019 | 0.0005 | 0.0058 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0043 | 0.0259 | 0.0639 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0275 | 0.277 | 0.6845 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0597 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0144 | 0.0447 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Brugia malayi | nuclear receptor NHR-88 | 0.0032 | 0.0144 | 0.0461 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0019 | 0.0005 | 0.0011 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0037 | 0.0191 | 0.0613 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0032 | 0.0144 | 0.0745 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0778 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0144 | 0.0447 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0043 | 0.0259 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0032 | 0.0144 | 0.0745 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0778 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0043 | 0.0259 | 0.3324 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0005 | 0.0076 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0043 | 0.0259 | 0.3324 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0037 | 0.0191 | 0.0599 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0778 | 0.2487 |
Plasmodium falciparum | thioredoxin reductase | 0.0055 | 0.0389 | 0.4999 |
Echinococcus granulosus | peptidase Clp S14 family | 0.006 | 0.0439 | 0.1085 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0091 | 0.0778 | 1 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0068 | 0.0534 | 0.1702 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0032 | 0.0144 | 0.0144 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0071 | 0.0558 | 0.9351 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0032 | 0.0144 | 0.0144 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0032 | 0.0144 | 0.0144 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0032 | 0.0144 | 0.0461 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0091 | 0.0778 | 1 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0043 | 0.0259 | 0.3324 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0144 | 0.0447 |
Echinococcus granulosus | tumor protein p63 | 0.0393 | 0.4047 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.0005 | 0.0005 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.0597 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0068 | 0.0534 | 0.1714 |
Onchocerca volvulus | 0.0056 | 0.0401 | 0.9626 | |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0068 | 0.0534 | 0.0534 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0032 | 0.0144 | 0.0461 |
Echinococcus multilocularis | GPCR, family 2 | 0.0037 | 0.0191 | 0.0191 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0056 | 0.0401 | 0.1287 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0071 | 0.0558 | 0.1379 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0032 | 0.0144 | 0.0355 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0144 | 0.0447 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0125 | 0.1151 | 0.8837 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0259 | 0.4335 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0091 | 0.0778 | 0.4039 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0005 | 0.0076 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0005 | 0.0023 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0125 | 0.1151 | 0.8837 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0091 | 0.0778 | 0.5514 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Brugia malayi | jmjC domain containing protein | 0.0068 | 0.0534 | 0.1714 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0019 | 0.0005 | 0.0076 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.006 | 0.0439 | 0.0439 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0032 | 0.0144 | 0.3378 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0037 | 0.0191 | 0.0472 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.1927 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0067 | 0.0516 | 0.663 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0005 | 0.0014 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0068 | 0.0534 | 0.0534 |
Brugia malayi | hypothetical protein | 0.0275 | 0.277 | 0.8893 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0005 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0275 | 0.277 | 0.8892 |
Schistosoma mansoni | coup transcription factor | 0.0032 | 0.0144 | 0.0745 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0032 | 0.0144 | 0.0745 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0055 | 0.0389 | 0.1236 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0558 | 0.7172 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.0259 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0032 | 0.0144 | 0.0144 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0125 | 0.1151 | 0.8837 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0032 | 0.0144 | 0.0461 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0778 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0032 | 0.0144 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0144 | 0.0447 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0071 | 0.0558 | 0.4283 |
Echinococcus granulosus | geminin | 0.0197 | 0.1927 | 0.4761 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0019 | 0.0005 | 0.0058 |
Brugia malayi | nuclear hormone receptor | 0.0032 | 0.0144 | 0.0461 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0032 | 0.0144 | 0.0461 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0074 | 0.0597 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0005 | 0.0014 |
Schistosoma mansoni | thyroid hormone receptor | 0.0032 | 0.0144 | 0.0745 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0091 | 0.0778 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Leishmania major | trypanothione reductase | 0.0055 | 0.0389 | 0.6518 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0116 | 0.1049 | 0.3357 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0068 | 0.0534 | 0.132 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0071 | 0.0558 | 0.7172 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0079 | 0.0652 | 0.2092 |
Echinococcus granulosus | nuclear receptor co repressor related ncor | 0.032 | 0.3262 | 0.806 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0068 | 0.0534 | 0.2772 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.1049 | 0.3357 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0275 | 0.277 | 0.277 |
Schistosoma mansoni | jumonji domain containing protein | 0.0068 | 0.0534 | 0.2772 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.0005 | 0.0005 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0139 | 0.1303 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0055 | 0.0389 | 0.4999 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0558 | 0.7172 |
Echinococcus multilocularis | geminin | 0.0197 | 0.1927 | 0.1927 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.0005 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.1927 | 1 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0031 | 0.0133 | 0.1708 |
Loa Loa (eye worm) | hypothetical protein | 0.0307 | 0.3115 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0778 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0055 | 0.0389 | 0.2985 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.0597 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0032 | 0.0144 | 0.0447 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0067 | 0.0516 | 0.1656 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0032 | 0.0144 | 0.0355 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Brugia malayi | Thioredoxin reductase | 0.0055 | 0.0389 | 0.1249 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0416 | 0.1324 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0038 | 0.021 | 0.0659 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0032 | 0.0144 | 0.0461 |
Echinococcus multilocularis | tumor protein p63 | 0.0393 | 0.4047 | 0.4047 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0259 | 0.4335 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0032 | 0.0144 | 0.0745 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0558 | 0.2896 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0778 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0191 | 0.0599 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.0259 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.0005 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.0652 | 0.3382 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0597 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0032 | 0.0144 | 0.0447 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0071 | 0.0558 | 0.0558 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.006 | 0.0439 | 0.2616 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0005 | 0.0076 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0032 | 0.0144 | 0.0355 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0597 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0778 | 1 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0067 | 0.0516 | 0.1275 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0055 | 0.0389 | 0.6518 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0032 | 0.0144 | 0.0461 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0032 | 0.0144 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0144 | 0.0447 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0055 | 0.0389 | 0.0389 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0032 | 0.0144 | 0.0745 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0032 | 0.0144 | 0.0144 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0032 | 0.0144 | 0.0745 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0032 | 0.0144 | 0.0461 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0032 | 0.0144 | 0.0461 |
Mycobacterium tuberculosis | Probable reductase | 0.0125 | 0.1151 | 0.8837 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0191 | 0.099 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0005 | 0.0014 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.0597 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0032 | 0.0144 | 0.0144 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0091 | 0.0778 | 0.1923 |
Echinococcus granulosus | GPCR family 2 | 0.0037 | 0.0191 | 0.0472 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0032 | 0.0144 | 0.0355 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0032 | 0.0144 | 0.0461 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0032 | 0.0144 | 0.0745 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0139 | 0.1303 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0597 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0259 | 0.4335 |
Trypanosoma brucei | trypanothione reductase | 0.0055 | 0.0389 | 0.6518 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0032 | 0.0144 | 0.0745 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0067 | 0.0516 | 0.3959 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0043 | 0.0259 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0597 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0597 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0032 | 0.0144 | 0.0355 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0125 | 0.1151 | 0.8705 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0062 | 0.0467 | 0.1488 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0058 | 0.0425 | 0.712 |
Brugia malayi | Probable ClpP-like protease | 0.0091 | 0.0778 | 0.2498 |
Echinococcus granulosus | FTZ F1 alpha | 0.0032 | 0.0144 | 0.0355 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0116 | 0.1049 | 0.3367 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0259 | 0.4335 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0032 | 0.0144 | 0.0144 |
Toxoplasma gondii | hypothetical protein | 0.0031 | 0.0133 | 0.1708 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0597 | 1 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0057 | 0.0416 | 0.2161 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.006 | 0.0439 | 0.3369 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0032 | 0.0144 | 0.0447 |
Plasmodium vivax | vivapain-2 | 0.0019 | 0.0005 | 0.0058 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0032 | 0.0144 | 0.0461 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0032 | 0.0144 | 0.0461 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0032 | 0.0144 | 0.0461 |
Schistosoma mansoni | nuclear hormone receptor | 0.0032 | 0.0144 | 0.0745 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0032 | 0.0144 | 0.3378 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0032 | 0.0144 | 0.0461 |
Brugia malayi | steroid hormone receptor | 0.0032 | 0.0144 | 0.0461 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0005 | 0.0076 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0032 | 0.0144 | 0.0355 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0055 | 0.0389 | 0.4999 |
Toxoplasma gondii | cathepsin CPL | 0.0019 | 0.0005 | 0.0058 |
Brugia malayi | glutathione reductase | 0.0055 | 0.0389 | 0.1249 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0125 | 0.1151 | 0.8837 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0005 | 0.0023 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.0597 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.0055 | 0.0389 | 0.4999 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.0259 | 0.1343 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0037 | 0.0191 | 0.0472 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0558 | 0.7172 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0019 | 0.0005 | 0.0058 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0597 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0032 | 0.0144 | 0.0461 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0032 | 0.0144 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0144 | 0.0447 |
Echinococcus multilocularis | nuclear receptor co repressor related (ncor) | 0.032 | 0.3262 | 0.3262 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0307 | 0.3115 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0032 | 0.0144 | 0.0355 |
Echinococcus granulosus | cathepsin l1 | 0.0019 | 0.0005 | 0.0011 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0067 | 0.0516 | 0.0516 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0032 | 0.0144 | 0.0745 |
Brugia malayi | Inositol-1 | 0.0043 | 0.0259 | 0.083 |
Schistosoma mansoni | hypothetical protein | 0.0056 | 0.0401 | 0.2081 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0031 | 0.0133 | 0.1708 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0005 | 0.0014 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0597 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0032 | 0.0144 | 0.0447 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0032 | 0.0144 | 0.0745 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0037 | 0.0191 | 0.0613 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0067 | 0.0516 | 0.2677 |
Loa Loa (eye worm) | inositol-1 | 0.0043 | 0.0259 | 0.0817 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0031 | 0.0133 | 0.1708 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0037 | 0.0191 | 0.0191 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0032 | 0.0144 | 0.0144 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0191 | 0.099 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0116 | 0.1049 | 0.3367 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0068 | 0.0527 | 0.8832 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0125 | 0.1151 | 0.8837 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0032 | 0.0144 | 0.0447 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0597 | 1 |
Onchocerca volvulus | 0.0032 | 0.0144 | 0.3378 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0558 | 0.2896 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0037 | 0.0191 | 0.0191 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0091 | 0.0778 | 1 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.0597 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0191 | 0.099 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Brugia malayi | ecdysteroid receptor | 0.0032 | 0.0144 | 0.0461 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0055 | 0.0389 | 0.0961 |
Plasmodium vivax | glutathione reductase, putative | 0.0055 | 0.0389 | 0.4999 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0597 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.0005 | 0.0005 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0091 | 0.0778 | 0.0778 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0005 | 0.0174 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0019 | 0.0005 | 0.0014 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0032 | 0.0144 | 0.3378 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.0597 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0019 | 0.0005 | 0.0011 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.