Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.052 | 0.052 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.6221 | 1 |
Echinococcus granulosus | geminin | 0.0175 | 0.6221 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4199 | 0.6751 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0704 | 0.0704 |
Echinococcus granulosus | tar DNA binding protein | 0.0129 | 0.4199 | 0.6454 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4199 | 0.6751 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.052 | 0.0836 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.018 | 0.6446 | 0.1027 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0129 | 0.4199 | 0.4199 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.052 | 0.052 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4199 | 0.6751 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0129 | 0.4199 | 0.4199 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4199 | 0.6751 |
Loa Loa (eye worm) | RNA binding protein | 0.0129 | 0.4199 | 0.4199 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0129 | 0.4199 | 0.4199 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4199 | 0.6751 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.018 | 0.6446 | 0.1027 |
Echinococcus multilocularis | tar DNA binding protein | 0.0129 | 0.4199 | 0.6454 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0704 | 0.0704 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0175 | 0.6221 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0704 | 0.0704 |
Brugia malayi | TAR-binding protein | 0.0129 | 0.4199 | 0.4199 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0171 | 0.6039 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0129 | 0.4199 | 0.4199 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.026 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.6221 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0704 | 0.0704 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.052 | 0.0836 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.052 | 0.0836 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.