Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0547 | 0.0547 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.028 | 0.1635 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.028 | 0.1635 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0006 | 0.0222 | 0.5 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.035 | 0.035 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.028 | 0.1635 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.028 | 0.1635 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0006 | 0.0222 | 0.0222 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.028 | 0.1635 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.2952 | 0.2952 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.2769 | 0.2769 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0101 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0547 | 0.0547 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.1713 | 0.1713 |
Echinococcus multilocularis | dna polymerase kappa | 0.0021 | 0.1713 | 0.1713 |
Loa Loa (eye worm) | TAR-binding protein | 0.0071 | 0.6925 | 0.6925 |
Echinococcus granulosus | tar DNA binding protein | 0.0071 | 0.6925 | 0.6925 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0066 | 0.6376 | 0.6376 |
Echinococcus granulosus | dna polymerase kappa | 0.0021 | 0.1713 | 0.1713 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.6925 | 0.6925 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0222 | 0.0222 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0021 | 0.1713 | 0.1713 |
Schistosoma mansoni | DNA polymerase eta | 0.0021 | 0.1713 | 0.1713 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.1042 | 0.55 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.028 | 0.1635 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.035 | 0.035 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.028 | 0.1635 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.1713 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0021 | 0.1713 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.6925 | 0.6925 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.1713 | 0.5 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0013 | 0.0013 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.028 | 0.1635 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.028 | 0.1635 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 0.1713 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.028 | 0.1635 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.1042 | 0.55 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.6925 | 0.6925 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0101 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0101 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0101 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0101 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.1713 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0006 | 0.0222 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.028 | 0.1635 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0071 | 0.6925 | 0.6925 |
Brugia malayi | polk-prov protein | 0.0006 | 0.0222 | 0.0222 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.1713 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.5647 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0021 | 0.1713 | 0.1713 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.028 | 0.1635 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0021 | 0.1713 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0021 | 0.1713 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0071 | 0.6925 | 0.6925 |
Trypanosoma brucei | unspecified product | 0.0021 | 0.1713 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.2769 | 0.2769 |
Brugia malayi | TAR-binding protein | 0.0071 | 0.6925 | 0.6925 |
Leishmania major | DNA polymerase eta, putative | 0.0021 | 0.1713 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.2952 | 0.2952 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0021 | 0.1713 | 1 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.035 | 0.035 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.1713 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.1713 | 0.1713 |
Loa Loa (eye worm) | RNA binding protein | 0.0071 | 0.6925 | 0.6925 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.1042 | 0.55 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.1713 | 0.1713 |
Onchocerca volvulus | 0.0031 | 0.2769 | 1 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.2952 | 0.2952 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0021 | 0.1713 | 0.1713 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.028 | 0.1635 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0534 | 0.0534 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.1713 | 0.1713 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.035 | 0.035 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.2769 | 0.2769 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0101 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0071 | 0.6925 | 0.6925 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.028 | 0.1635 |
Echinococcus granulosus | dna polymerase eta | 0.0021 | 0.1713 | 0.1713 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.028 | 0.1635 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.035 | 0.035 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0021 | 0.1713 | 0.1713 |
Echinococcus multilocularis | tar DNA binding protein | 0.0071 | 0.6925 | 0.6925 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.1042 | 0.55 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.1042 | 0.55 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.6925 | 0.6925 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.2952 | 0.2952 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.6925 | 0.6925 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.1713 | 0.1713 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0021 | 0.1713 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.028 | 0.1635 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.1713 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0101 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.028 | 0.1635 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0547 | 0.0547 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0101 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.1713 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0.1713 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.028 | 0.1635 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.1713 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.