Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0142 | 0.1676 |
Brugia malayi | jmjC domain containing protein | 0.0057 | 0.03 | 0.0787 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0093 | 0.0553 | 0.0553 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.003 | 0.0103 | 0.1218 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.003 | 0.0103 | 0.1218 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0159 | 0.1024 | 0.2688 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0093 | 0.0553 | 0.0553 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0553 | 0.1452 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0103 | 0.1218 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0218 | 0.1446 | 0.4209 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0082 | 0.0082 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.003 | 0.0103 | 0.1218 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0045 | 0.0212 | 0.4208 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0093 | 0.0553 | 0.6307 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0436 | 0.2445 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0041 | 0.0185 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0047 | 0.0924 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0103 | 0.1218 |
Mycobacterium tuberculosis | Conserved protein | 0.0076 | 0.0436 | 0.117 |
Schistosoma mansoni | jumonji domain containing protein | 0.0057 | 0.03 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0436 | 0.1144 |
Plasmodium vivax | hypothetical protein, conserved | 0.0076 | 0.0436 | 0.864 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0076 | 0.0436 | 0.4846 |
Brugia malayi | Carboxylesterase family protein | 0.0093 | 0.0553 | 0.1452 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0148 | 0.0389 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0082 | 0.0214 |
Mycobacterium ulcerans | putative regulatory protein | 0.0037 | 0.0153 | 0.1326 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0553 | 0.1452 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0041 | 0.0185 | 0.3677 |
Schistosoma mansoni | apoptosis regulator bax | 0.0085 | 0.0501 | 0.0501 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0553 | 0.1452 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0076 | 0.0436 | 0.864 |
Plasmodium falciparum | glutathione reductase | 0.0086 | 0.0504 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0134 | 0.0849 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1415 | 1 | 1 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.0148 | 0.2937 |
Loa Loa (eye worm) | hypothetical protein | 0.0173 | 0.1127 | 0.2959 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0086 | 0.0504 | 0.1324 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0085 | 0.0501 | 0.0501 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0196 | 0.129 | 0.374 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0142 | 0.0905 | 0.2375 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0142 | 0.0905 | 0.0905 |
Brugia malayi | beta-lactamase | 0.0076 | 0.0436 | 0.1144 |
Plasmodium falciparum | thioredoxin reductase | 0.003 | 0.0103 | 0.2052 |
Echinococcus granulosus | muscleblind protein | 0.0173 | 0.1127 | 0.1127 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0093 | 0.0553 | 0.1523 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0037 | 0.0153 | 0.0153 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0078 | 0.0206 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0142 | 0.0602 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0103 | 0.2052 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0082 | 0.0082 |
Plasmodium falciparum | thioredoxin reductase | 0.0086 | 0.0504 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0245 | 0.1637 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0076 | 0.0436 | 0.864 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0036 | 0.0148 | 0.0148 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0093 | 0.0553 | 0.0553 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0093 | 0.0553 | 0.0553 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0149 | 0.0952 | 0.0952 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0022 | 0.0047 | 0.0548 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0436 | 0.1144 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.003 | 0.0103 | 0.0708 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0082 | 0.0214 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0057 | 0.03 | 0.0787 |
Onchocerca volvulus | 0.0031 | 0.0111 | 0.0189 | |
Brugia malayi | bHLH-PAS transcription factor | 0.0037 | 0.0153 | 0.0402 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0078 | 0.1556 |
Trichomonas vaginalis | glutathione reductase, putative | 0.003 | 0.0103 | 0.0358 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0085 | 0.0501 | 0.0501 |
Trichomonas vaginalis | mercuric reductase, putative | 0.003 | 0.0103 | 0.0358 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0455 | 0.3137 | 0.3137 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0076 | 0.0436 | 0.117 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0142 | 0.6899 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0159 | 0.1024 | 0.1024 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0036 | 0.0148 | 0.0389 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.0148 | 0.2937 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0085 | 0.0501 | 0.0501 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0215 | 0.1425 | 0.3743 |
Loa Loa (eye worm) | hypothetical protein | 0.0549 | 0.3808 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0076 | 0.0436 | 0.4846 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0022 | 0.0047 | 0.0122 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0103 | 0.2052 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0036 | 0.0148 | 0.7313 |
Schistosoma mansoni | single-minded | 0.005 | 0.0245 | 0.0245 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0553 | 0.1452 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0086 | 0.0504 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0076 | 0.0436 | 0.0436 |
Plasmodium vivax | glutathione reductase, putative | 0.0086 | 0.0504 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0093 | 0.0553 | 0.1452 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0153 | 0.0983 | 0.0983 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0153 | 0.0983 | 0.2581 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0078 | 0.0206 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0159 | 0.1024 | 0.2688 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0036 | 0.0148 | 0.0148 |
Onchocerca volvulus | 0.0245 | 0.1637 | 1 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0093 | 0.0553 | 0.1523 |
Brugia malayi | jmjC domain containing protein | 0.0057 | 0.03 | 0.0787 |
Schistosoma mansoni | alpha-glucosidase | 0.0137 | 0.0866 | 0.0866 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0036 | 0.0148 | 0.0148 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.003 | 0.0103 | 0.2052 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0111 | 0.0111 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0045 | 0.0212 | 0.2497 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0035 | 0.0142 | 0.0142 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.003 | 0.0103 | 0.2052 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0142 | 0.0905 | 0.0905 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0047 | 0.0924 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0022 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0076 | 0.0436 | 0.1144 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0076 | 0.0436 | 0.2445 |
Echinococcus multilocularis | acetylcholinesterase | 0.0549 | 0.3808 | 0.3808 |
Brugia malayi | Carboxylesterase family protein | 0.0549 | 0.3808 | 1 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0036 | 0.0148 | 0.0148 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0022 | 0.0047 | 0.0047 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0142 | 0.0602 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0553 | 0.1452 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0022 | 0.0047 | 0.0123 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0111 | 0.0111 |
Schistosoma mansoni | gliotactin | 0.0093 | 0.0553 | 0.0553 |
Toxoplasma gondii | thioredoxin reductase | 0.0086 | 0.0504 | 0.5935 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0057 | 0.03 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0436 | 0.1144 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.005 | 0.0245 | 0.0245 |
Schistosoma mansoni | lamin | 0.0027 | 0.0082 | 0.0082 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0082 | 0.0214 |
Mycobacterium tuberculosis | Conserved protein | 0.0076 | 0.0436 | 0.117 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0057 | 0.03 | 0.03 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0103 | 0.2052 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0041 | 0.0185 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0057 | 0.03 | 0.03 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0142 | 0.0602 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0111 | 0.0111 |
Brugia malayi | hypothetical protein | 0.0093 | 0.0553 | 0.1452 |
Brugia malayi | Carboxylesterase family protein | 0.0093 | 0.0553 | 0.1452 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0057 | 0.03 | 0.03 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0078 | 0.1556 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0111 | 0.0111 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0455 | 0.3137 | 0.3137 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0076 | 0.0436 | 0.0436 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.0501 | 0.0501 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0142 | 0.6899 |
Brugia malayi | Carboxylesterase family protein | 0.0093 | 0.0553 | 0.1452 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.0905 | 0.0905 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0085 | 0.0501 | 0.1317 |
Brugia malayi | hypoxia-induced factor 1 | 0.0153 | 0.0987 | 0.2591 |
Brugia malayi | Pre-SET motif family protein | 0.0215 | 0.1425 | 0.3743 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0036 | 0.0148 | 0.0148 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0035 | 0.0142 | 0.0374 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0085 | 0.0501 | 0.0501 |
Onchocerca volvulus | 0.0092 | 0.0546 | 0.2986 | |
Echinococcus multilocularis | neuroligin | 0.0093 | 0.0553 | 0.0553 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.003 | 0.0103 | 0.0103 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0196 | 0.129 | 0.374 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0111 | 0.1307 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0142 | 0.0602 |
Loa Loa (eye worm) | acetyltransferase | 0.0153 | 0.0983 | 0.2581 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.003 | 0.0103 | 0.2052 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0436 | 0.2445 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0159 | 0.1024 | 0.1024 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0111 | 0.0292 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0035 | 0.0142 | 0.0602 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0036 | 0.0148 | 0.0148 |
Brugia malayi | beta-lactamase family protein | 0.0076 | 0.0436 | 0.1144 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0076 | 0.0436 | 0.0436 |
Brugia malayi | hypothetical protein | 0.0166 | 0.1079 | 0.2832 |
Leishmania major | trypanothione reductase | 0.0086 | 0.0504 | 0.5935 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0093 | 0.0553 | 0.1523 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0085 | 0.0501 | 0.0501 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0436 | 0.1144 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0036 | 0.0148 | 0.0638 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0436 | 0.1144 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0036 | 0.0148 | 0.0148 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0022 | 0.0047 | 0.0924 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0076 | 0.0436 | 0.864 |
Brugia malayi | follicle stimulating hormone receptor | 0.0229 | 0.1528 | 0.4012 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0134 | 0.0849 | 0.0849 |
Schistosoma mansoni | hypothetical protein | 0.0514 | 0.3561 | 0.3561 |
Brugia malayi | beta-lactamase family protein | 0.0076 | 0.0436 | 0.1144 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0153 | 0.0987 | 0.2591 |
Schistosoma mansoni | alpha-glucosidase | 0.0137 | 0.0866 | 0.0866 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0076 | 0.0436 | 0.1144 |
Onchocerca volvulus | 0.0093 | 0.0553 | 0.3029 | |
Echinococcus granulosus | single minded 2 | 0.0037 | 0.0153 | 0.0153 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.003 | 0.0103 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0173 | 0.1127 | 0.2959 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.0501 | 0.0501 |
Trypanosoma brucei | glucosidase, putative | 0.0035 | 0.0142 | 0.2823 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0436 | 0.1144 |
Loa Loa (eye worm) | carboxylesterase | 0.0093 | 0.0553 | 0.1452 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.003 | 0.0103 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0086 | 0.0504 | 0.1324 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0501 | 0.1317 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0047 | 0.0047 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0142 | 0.2823 |
Echinococcus granulosus | lamin | 0.0027 | 0.0082 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.0549 | 0.3808 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0086 | 0.0504 | 0.1377 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0076 | 0.0436 | 0.4846 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.003 | 0.0103 | 0.2052 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0153 | 0.0983 | 0.0983 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.003 | 0.0103 | 0.2052 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0045 | 0.0212 | 0.1041 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.003 | 0.0103 | 0.2052 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0196 | 0.129 | 0.374 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0076 | 0.0436 | 0.117 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0076 | 0.0436 | 0.117 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.003 | 0.0103 | 0.0708 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0553 | 0.1452 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.003 | 0.0103 | 0.2052 |
Schistosoma mansoni | acetylcholinesterase | 0.0093 | 0.0553 | 0.0553 |
Plasmodium falciparum | glutathione reductase | 0.003 | 0.0103 | 0.2052 |
Echinococcus granulosus | neuroligin | 0.0093 | 0.0553 | 0.0553 |
Loa Loa (eye worm) | carboxylesterase | 0.0093 | 0.0553 | 0.1452 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0093 | 0.0553 | 0.3183 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.003 | 0.0103 | 0.2052 |
Loa Loa (eye worm) | beta-lactamase | 0.0076 | 0.0436 | 0.1144 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0134 | 0.0849 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0111 | 0.0111 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0047 | 0.0924 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0035 | 0.0142 | 0.1676 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0111 | 0.0111 |
Schistosoma mansoni | hypothetical protein | 0.0514 | 0.3561 | 0.3561 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0078 | 0.1556 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0111 | 0.0292 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0076 | 0.0436 | 0.2445 |
Echinococcus granulosus | geminin | 0.0514 | 0.3561 | 0.3561 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0553 | 0.1452 |
Brugia malayi | Muscleblind-like protein | 0.0173 | 0.1127 | 0.2959 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0111 | 0.0111 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0076 | 0.0436 | 0.0436 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.003 | 0.0103 | 0.1218 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0134 | 0.0849 | 0.0849 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0134 | 0.0849 | 0.2415 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.003 | 0.0103 | 0.2052 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0082 | 0.0214 |
Toxoplasma gondii | ABC1 family protein | 0.0076 | 0.0436 | 0.5128 |
Leishmania major | hypothetical protein, conserved | 0.0076 | 0.0436 | 0.5128 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0076 | 0.0436 | 0.117 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1415 | 1 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0086 | 0.0504 | 0.1324 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0173 | 0.1127 | 0.1127 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0045 | 0.0212 | 0.2497 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0142 | 0.0905 | 0.0905 |
Onchocerca volvulus | 0.0093 | 0.0553 | 0.3029 | |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0103 | 0.2052 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0012 | 0.0032 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0093 | 0.0553 | 0.0553 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0086 | 0.0508 | 0.0508 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0076 | 0.0436 | 0.117 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0082 | 0.0082 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.003 | 0.0103 | 0.0272 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.003 | 0.0103 | 0.0171 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0218 | 0.1446 | 0.4209 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0082 | 0.0082 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.0501 | 0.0501 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.003 | 0.0103 | 0.5 |
Mycobacterium ulcerans | beta-lactamase | 0.0076 | 0.0436 | 0.4846 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0142 | 0.0602 |
Trichomonas vaginalis | esterase, putative | 0.0076 | 0.0436 | 0.2445 |
Brugia malayi | glutathione reductase | 0.0086 | 0.0504 | 0.1324 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.003 | 0.0103 | 0.0708 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0047 | 0.0047 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0078 | 0.1556 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0082 | 0.0082 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0196 | 0.129 | 0.374 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0022 | 0.0047 | 0.0122 |
Onchocerca volvulus | 0.0093 | 0.0553 | 0.3029 | |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0093 | 0.0553 | 0.0553 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0134 | 0.0849 | 0.0849 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0142 | 0.0602 |
Echinococcus granulosus | acetylcholinesterase | 0.0549 | 0.3808 | 0.3808 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0035 | 0.0142 | 0.0602 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0085 | 0.0501 | 0.1317 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0103 | 0.2052 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0076 | 0.0436 | 0.117 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0035 | 0.0142 | 0.0142 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0093 | 0.0553 | 0.0553 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0134 | 0.0849 | 0.0849 |
Echinococcus multilocularis | acetylcholinesterase | 0.0549 | 0.3808 | 0.3808 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0035 | 0.0142 | 0.0374 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0078 | 0.1556 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0549 | 0.3808 | 1 |
Onchocerca volvulus | 0.0076 | 0.0436 | 0.2275 | |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0057 | 0.03 | 0.03 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0047 | 0.0924 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0036 | 0.0148 | 0.1743 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0134 | 0.0849 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0093 | 0.0553 | 0.0553 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0487 | 0.337 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0086 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0078 | 0.0205 |
Mycobacterium ulcerans | lipase LipD | 0.0076 | 0.0436 | 0.4846 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0057 | 0.03 | 0.03 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0134 | 0.0849 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0142 | 0.0602 |
Onchocerca volvulus | 0.0093 | 0.0553 | 0.3029 | |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0076 | 0.0436 | 0.117 |
Onchocerca volvulus | 0.0037 | 0.0153 | 0.0459 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.0905 | 0.0905 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0218 | 0.1446 | 1 |
Onchocerca volvulus | 0.0076 | 0.0436 | 0.2275 | |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0455 | 0.3137 | 0.3137 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0086 | 0.0504 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0142 | 0.2823 |
Echinococcus granulosus | neuropeptide s receptor | 0.0455 | 0.3137 | 0.3137 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0196 | 0.129 | 0.8455 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0111 | 0.2203 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0082 | 0.0214 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0078 | 0.0924 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.0148 | 0.2937 |
Toxoplasma gondii | exonuclease III APE | 0.0022 | 0.0047 | 0.0548 |
Loa Loa (eye worm) | carboxylesterase | 0.0549 | 0.3808 | 1 |
Onchocerca volvulus | 0.0093 | 0.0553 | 0.3029 | |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0229 | 0.1528 | 0.4012 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0549 | 0.3808 | 0.3808 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0036 | 0.0148 | 0.0148 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0093 | 0.0553 | 0.0553 |
Trypanosoma brucei | trypanothione reductase | 0.0086 | 0.0504 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.0905 | 0.0905 |
Echinococcus multilocularis | geminin | 0.0514 | 0.3561 | 0.3561 |
Brugia malayi | Carboxylesterase family protein | 0.0549 | 0.3808 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.003 | 0.0103 | 0.2052 |
Echinococcus granulosus | carboxylesterase 5A | 0.0549 | 0.3808 | 0.3808 |
Treponema pallidum | NADH oxidase | 0.003 | 0.0103 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0082 | 0.0082 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0148 | 0.0638 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0078 | 0.0924 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0549 | 0.3808 | 0.3808 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0078 | 0.1556 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0159 | 0.1024 | 0.1024 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0093 | 0.0553 | 0.3183 |
Mycobacterium tuberculosis | Probable reductase | 0.0196 | 0.129 | 0.374 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0103 | 0.0103 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0022 | 0.0047 | 0.0123 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.003 | 0.0103 | 0.0103 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.003 | 0.0103 | 0.2052 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0045 | 0.0212 | 0.1041 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0134 | 0.0849 | 1 |
Onchocerca volvulus | 0.0076 | 0.0436 | 0.2275 | |
Echinococcus multilocularis | muscleblind protein | 0.0173 | 0.1127 | 0.1127 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0436 | 0.2445 |
Brugia malayi | PAS domain containing protein | 0.005 | 0.0245 | 0.0643 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0045 | 0.0212 | 0.0212 |
Schistosoma mansoni | alpha glucosidase | 0.0035 | 0.0142 | 0.0142 |
Echinococcus granulosus | acetylcholinesterase | 0.0549 | 0.3808 | 0.3808 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0103 | 0.2052 |
Mycobacterium tuberculosis | Conserved protein | 0.0076 | 0.0436 | 0.117 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.003 | 0.0103 | 0.0103 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0142 | 0.0905 | 0.0905 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.003 | 0.0103 | 0.4097 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0036 | 0.0148 | 0.7313 |
Schistosoma mansoni | lamin | 0.0027 | 0.0082 | 0.0082 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0196 | 0.129 | 0.374 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0218 | 0.1446 | 0.4209 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0093 | 0.0553 | 0.0553 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0036 | 0.0148 | 0.0638 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1079 | 0.2832 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0142 | 0.0905 | 0.2375 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0093 | 0.0553 | 0.0553 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 45 uM | Binding affinity against Sodium/glucose cotransporter of isolated renal brush border membranes. | ChEMBL. | 10794686 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.