Detailed information for compound 1699730

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 698.679 | Formula: C36H45Cl2N5O5
  • H donors: 4 H acceptors: 4 LogP: 5.01 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC[C@@H](N1C[C@@H](C)[C@@H](CN(Cc2ccc(c(c2)Cl)Cl)C)Oc2c(C1=O)cccc2NC(=O)CCCCCC(=O)Nc1ccccc1N)C
  • InChi: 1S/C36H45Cl2N5O5/c1-23-19-43(24(2)22-44)36(47)26-10-9-13-31(35(26)48-32(23)21-42(3)20-25-16-17-27(37)28(38)18-25)41-34(46)15-6-4-5-14-33(45)40-30-12-8-7-11-29(30)39/h7-13,16-18,23-24,32,44H,4-6,14-15,19-22,39H2,1-3H3,(H,40,45)(H,41,46)/t23-,24+,32-/m1/s1
  • InChiKey: KPNIWBUOMWGGPJ-MKVNITDJSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0042 0.1145 0.1227
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.7086 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0017 0.016 0.0555
Schistosoma mansoni inositol monophosphatase 0.0039 0.101 0.1396
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0612 0.3177
Echinococcus granulosus multidrug resistance protein 1 0.0013 0.0023 0.0023
Echinococcus granulosus zinc finger protein 0.0021 0.0337 0.034
Echinococcus multilocularis tar DNA binding protein 0.0066 0.2088 0.2107
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0061 0.1877 1
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.1145 0.1125
Mycobacterium tuberculosis Conserved protein 0.0042 0.1145 0.1125
Brugia malayi hypothetical protein 0.0018 0.0219 0.0198
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0612 0.3177
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.2505 0.3462
Toxoplasma gondii ABC1 family protein 0.0042 0.1145 0.159
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0102 0.3466 0.3498
Echinococcus granulosus tar DNA binding protein 0.0066 0.2088 0.2107
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0852 0.0831
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0017 0.016 0.0033
Giardia lamblia Multidrug resistance-associated protein 1 0.0017 0.016 0.005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0152 0.0139
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.1145 0.1156
Schistosoma mansoni multidrug resistance protein 0.0017 0.016 0.0222
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.1145 0.1227
Echinococcus multilocularis zinc finger protein 0.0021 0.0337 0.034
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0194 0.7086 1
Schistosoma mansoni hypothetical protein 0.0077 0.2505 0.3462
Schistosoma mansoni ap endonuclease 0.0061 0.1877 0.2594
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.101 0.1398
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0382 0.0372
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0017 0.016 0.0148
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.1145 0.5752
Schistosoma mansoni hypothetical protein 0.0017 0.0155 0.0214
Loa Loa (eye worm) TAR-binding protein 0.0066 0.2088 0.2096
Loa Loa (eye worm) hypothetical protein 0.0017 0.016 0.0148
Loa Loa (eye worm) hypothetical protein 0.0042 0.1145 0.1143
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0009
Loa Loa (eye worm) hypothetical protein 0.0267 0.9911 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0023 0.0023
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0612 0.2654
Giardia lamblia ABC transporter, putative 0.0017 0.016 0.005
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.2088 0.2096
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.2505 0.2528
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.101 0.4966
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0061 0.1877 0.1894
Brugia malayi Bromodomain containing protein 0.0042 0.1136 0.1126
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0067 0.2106 0.2089
Echinococcus multilocularis geminin 0.0198 0.7236 0.7301
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.1145 0.1143
Leishmania major hypothetical protein, conserved 0.0017 0.0155 0.0187
Loa Loa (eye worm) beta-lactamase 0.0042 0.1145 0.1143
Brugia malayi ABC transporter transmembrane region family protein 0.0017 0.016 0.0139
Brugia malayi multidrug resistance related protein 1 0.0017 0.016 0.0139
Schistosoma mansoni multidrug resistance protein 0.0013 0.0023 0.0031
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0023 0.0023
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0013 0.0023 0.5
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0102 0.3466 0.3498
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.1877 0.2027
Echinococcus granulosus histone lysine methyltransferase setb 0.005 0.1448 0.1461
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0067 0.2106 0.2911
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.2048 0.2067
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.1877 0.2027
Echinococcus granulosus multidrug resistance protein 1 0.0013 0.0023 0.0023
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.1877 1
Toxoplasma gondii aldehyde dehydrogenase 0.0194 0.7086 1
Leishmania major hypothetical protein, conserved 0.0028 0.0612 0.0834
Treponema pallidum exodeoxyribonuclease (exoA) 0.0061 0.1877 0.5
Leishmania major hypothetical protein, conserved 0.0042 0.1145 0.159
Schistosoma mansoni zinc finger protein 0.0021 0.0337 0.0466
Onchocerca volvulus 0.0042 0.1145 0.1227
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.2088 0.2089
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0102 0.3466 0.4791
Schistosoma mansoni multidrug resistance protein 0.0017 0.016 0.0222
Toxoplasma gondii exonuclease III APE 0.0061 0.1877 0.2625
Brugia malayi follicle stimulating hormone receptor 0.0246 0.9099 0.9179
Trypanosoma cruzi multidrug resistance protein E, putative 0.0017 0.016 0.0033
Schistosoma mansoni aldehyde dehydrogenase 0.0194 0.7086 0.9794
Brugia malayi Bromodomain containing protein 0.0082 0.2701 0.2708
Giardia lamblia MRP-like ABC transporter 0.0017 0.016 0.005
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0061 0.1877 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0721 0.0996
Echinococcus multilocularis multidrug resistance protein 1 0.0013 0.0023 0.0023
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0721 0.0727
Schistosoma mansoni tar DNA-binding protein 0.0066 0.2088 0.2886
Trichomonas vaginalis esterase, putative 0.0042 0.1145 0.1227
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.2505 0.2528
Entamoeba histolytica ATP-binding cassette protein, putative 0.0017 0.016 0.0555
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.1145 0.5752
Schistosoma mansoni hypothetical protein 0.0054 0.1625 0.2246
Entamoeba histolytica hypothetical protein 0.0077 0.2505 1
Schistosoma mansoni multidrug resistance protein 0.0013 0.0023 0.0031
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0023 0.0023
Entamoeba histolytica multidrug resistance protein, putative 0.0017 0.016 0.0555
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.101 0.1019
Onchocerca volvulus 0.0248 0.9172 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0023 0.0023
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0017 0.016 0.0195
Mycobacterium tuberculosis Conserved protein 0.0042 0.1145 0.1125
Schistosoma mansoni multidrug resistance protein 0.0013 0.0023 0.0031
Schistosoma mansoni hypothetical protein 0.0198 0.7236 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0067 0.2106 0.295
Mycobacterium ulcerans lipase LipD 0.0042 0.1145 0.0223
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0023 0.0023
Plasmodium vivax hypothetical protein, conserved 0.0042 0.1145 0.6055
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0013 0.0023 0.0009
Trypanosoma brucei p-glycoprotein 0.0017 0.016 0.0033
Loa Loa (eye worm) hypothetical protein 0.0044 0.124 0.1238
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0028 0.0612 0.0604
Loa Loa (eye worm) hypothetical protein 0.005 0.1448 0.1449
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0676 0.0682
Schistosoma mansoni tar DNA-binding protein 0.0066 0.2088 0.2886
Leishmania major ABC-thiol transporter 0.0017 0.016 0.0195
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.1145 0.1583
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.1784 0.1789
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0061 0.1877 0.1427
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0023 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0066 0.2088 0.2886
Loa Loa (eye worm) inositol-1 0.0039 0.101 0.1006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0102 0.3466 0.3498
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0017 0.016 0.0033
Schistosoma mansoni bromodomain containing protein 0.0069 0.2201 0.3042
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.101 0.1019
Loa Loa (eye worm) hypothetical protein 0.0047 0.1321 0.1321
Schistosoma mansoni tar DNA-binding protein 0.0066 0.2088 0.2886
Entamoeba histolytica ATP-binding cassette protein, putative 0.0017 0.016 0.0555
Brugia malayi hypothetical protein 0.0028 0.0612 0.0596
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0061 0.1877 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0102 0.3466 0.3498
Plasmodium vivax SET domain protein, putative 0.0031 0.0721 0.3765
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0061 0.1877 0.747
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0194 0.7086 0.708
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0061 0.1877 0.2625
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0246 0.9099 0.918
Brugia malayi PHD-finger family protein 0.0027 0.0565 0.0548
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.101 0.1079
Echinococcus multilocularis multidrug resistance associated protein 7 0.0017 0.016 0.0162
Entamoeba histolytica hypothetical protein 0.0017 0.016 0.0555
Brugia malayi beta-lactamase family protein 0.0042 0.1145 0.1136
Brugia malayi beta-lactamase 0.0042 0.1145 0.1136
Leishmania major p-glycoprotein e 0.0017 0.016 0.0195
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.1448 0.2002
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.1145 0.1125
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.1625 0.1621
Echinococcus multilocularis survival motor neuron protein 1 0.0267 0.9911 1
Onchocerca volvulus 0.0031 0.0721 0.0763
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0009
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0194 0.7086 0.715
Echinococcus granulosus geminin 0.0198 0.7236 0.7301
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.023 0.0317
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0102 0.3466 0.3488
Mycobacterium leprae Probable lipase LipE 0.0042 0.1145 1
Leishmania major pentamidine resistance protein 1 0.0017 0.016 0.0195
Entamoeba histolytica ATP-binding cassette protein, putative 0.0017 0.016 0.0555
Schistosoma mansoni multidrug resistance protein 0.0017 0.016 0.0222
Schistosoma mansoni tar DNA-binding protein 0.0066 0.2088 0.2886
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.1145 0.1125
Echinococcus multilocularis multidrug resistance protein 1 0.0013 0.0023 0.0023
Brugia malayi Pre-SET motif family protein 0.0218 0.7998 0.8066
Schistosoma mansoni aldehyde dehydrogenase 0.0194 0.7086 0.9794
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0061 0.1877 1
Loa Loa (eye worm) RNA binding protein 0.0066 0.2088 0.2096
Loa Loa (eye worm) hypothetical protein 0.0042 0.1139 0.1136
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.1145 0.1227
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.023 0.0232
Onchocerca volvulus 0.0054 0.1625 0.1752
Echinococcus granulosus survival motor neuron protein 1 0.0267 0.9911 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.1145 0.1143
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.1448 0.2002
Brugia malayi Pre-SET motif family protein 0.0031 0.0721 0.0706
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0102 0.3466 0.4791
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.101 0.1079
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.005 0.1448 0.1461
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0256 0.0244
Schistosoma mansoni smdr2 0.0013 0.0023 0.0031
Brugia malayi Inositol-1 0.0039 0.101 0.0999
Echinococcus multilocularis ATP binding cassette sub family B 0.0013 0.0014 0.0014
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0612 0.0834
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0017 0.016 0.0033
Entamoeba histolytica ABC transporter, putative 0.0017 0.016 0.0555
Schistosoma mansoni multidrug resistance protein 0.0017 0.016 0.0222
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0061 0.1877 0.1894
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0067 0.2106 0.2107
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0721 0.0996
Trichomonas vaginalis set domain proteins, putative 0.0248 0.9172 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0721 0.0988
Loa Loa (eye worm) hypothetical protein 0.0042 0.1145 0.1143
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0017 0.016 0.0195
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0218 0.7998 0.8067
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0017 0.016 0.0195
Loa Loa (eye worm) multidrug resistance protein 3 0.0013 0.0023 0.0009
Echinococcus granulosus multidrug resistance associated protein 1 0.0017 0.016 0.0162
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0017 0.016 0.0195
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0612 0.3177
Schistosoma mansoni ap endonuclease 0.0061 0.1877 0.2594
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0194 0.7086 0.715
Loa Loa (eye worm) hypothetical protein 0.0042 0.1145 0.1143
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.101 0.3977
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0464 0.0641
Mycobacterium ulcerans beta-lactamase 0.0042 0.1145 0.0223
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.1145 0.1156
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.1145 0.0223
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.101 0.4966
Brugia malayi TAR-binding protein 0.0066 0.2088 0.2089
Mycobacterium leprae conserved hypothetical protein 0.0042 0.1145 1
Giardia lamblia Multidrug resistance-associated protein 1 0.0017 0.016 0.005
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0023 0.0023
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0102 0.3466 0.3483
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0013 0.0014 0.0014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0102 0.3466 0.4791
Mycobacterium ulcerans hypothetical protein 0.0042 0.1145 0.0223
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0061 0.1877 0.1859
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.101 0.1079
Loa Loa (eye worm) hypothetical protein 0.0077 0.2518 0.253
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.1145 0.1125
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.2106 0.1804
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0464 0.0468
Loa Loa (eye worm) hypothetical protein 0.0042 0.1145 0.1143
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0023 0.0023
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.1145 0.1125
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.1035 0.1044
Onchocerca volvulus 0.0042 0.1145 0.1227
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.7086 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.1145 0.1583
Brugia malayi exodeoxyribonuclease III family protein 0.0061 0.1877 0.1875
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0612 0.2654
Entamoeba histolytica hypothetical protein 0.0077 0.2505 1
Schistosoma mansoni inositol monophosphatase 0.0039 0.101 0.1396
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0017 0.016 0.0033
Schistosoma mansoni survival motor neuron protein 0.0054 0.1625 0.2246
Echinococcus granulosus multidrug resistance associated protein 7 0.0017 0.016 0.0162
Trypanosoma brucei multidrug resistance protein E 0.0017 0.016 0.0033
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.1145 0.0223
Brugia malayi beta-lactamase family protein 0.0042 0.1145 0.1136
Loa Loa (eye worm) hypothetical protein 0.0042 0.1145 0.1143
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0061 0.1877 0.1883
Schistosoma mansoni zinc finger protein 0.0017 0.0155 0.0214
Echinococcus multilocularis multidrug resistance associated protein 1 0.0017 0.016 0.0162
Echinococcus granulosus multidrug resistance protein 1 0.0013 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.016 0.0148
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.1145 0.1136
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.023 0.0232
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.7086 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.2106 0.1804
Entamoeba histolytica hypothetical protein 0.0077 0.2505 1
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.2106 0.2125
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.1877 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.1145 0.1227
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.1145 0.1227
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.1145 0.1125
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.2106 0.2125
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.2048 0.2067
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.101 0.1398
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.023 0.0317
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.1145 0.5752
Schistosoma mansoni hypothetical protein 0.0023 0.0382 0.0528
Schistosoma mansoni hypothetical protein 0.0198 0.7236 1
Mycobacterium tuberculosis Conserved protein 0.0042 0.1145 0.1125
Entamoeba histolytica hypothetical protein 0.0077 0.2505 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.1145 0.1125
Brugia malayi RNA binding protein 0.0066 0.2088 0.2089
Brugia malayi hypothetical protein 0.0077 0.2505 0.2511
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.1145 0.1227
Brugia malayi hypothetical protein 0.0267 0.9911 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.1035 0.1044
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0061 0.1877 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0612 0.2654
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0017 0.016 0.0195
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.101 0.4966
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0464 0.0468

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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