Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 1 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.026 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.018 | 0.6446 | 0.1027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.018 | 0.6446 | 0.1027 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0129 | 0.4199 | 0.4199 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0175 | 0.6221 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.052 | 0.052 |
Echinococcus multilocularis | geminin | 0.0175 | 0.6221 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0704 | 0.0704 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.6221 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4199 | 0.6751 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0171 | 0.6039 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.052 | 0.052 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0129 | 0.4199 | 0.4199 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4199 | 0.6751 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.052 | 0.0836 |
Loa Loa (eye worm) | TAR-binding protein | 0.0129 | 0.4199 | 0.4199 |
Brugia malayi | RNA binding protein | 0.0129 | 0.4199 | 0.4199 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.026 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0129 | 0.4199 | 0.4199 |
Echinococcus granulosus | tar DNA binding protein | 0.0129 | 0.4199 | 0.6454 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0704 | 0.0704 |
Echinococcus multilocularis | tar DNA binding protein | 0.0129 | 0.4199 | 0.6454 |
Brugia malayi | TAR-binding protein | 0.0129 | 0.4199 | 0.4199 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4199 | 0.6751 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.052 | 0.0836 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4199 | 0.6751 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0704 | 0.0704 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0704 | 0.0704 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.4199 | 0.6751 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.052 | 0.0836 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.6221 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.