Detailed information for compound 170134

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 282.334 | Formula: C18H18O3
  • H donors: 0 H acceptors: 0 LogP: 2.94 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc(cc1)[C@@]12COC[C@](CC1)(OO2)c1ccccc1
  • InChi: 1S/C18H18O3/c1-3-7-15(8-4-1)17-11-12-18(21-20-17,14-19-13-17)16-9-5-2-6-10-16/h1-10H,11-14H2/t17-,18-/m0/s1
  • InChiKey: XWHNFOHHMIRASO-ROUUACIJSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) cytochrome P450 0.0162 0.2769 0.34
Loa Loa (eye worm) TK/CSK protein kinase 0.0089 0.1427 0.1751
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Echinococcus multilocularis FTZ F1 alpha 0.007 0.1068 0.1068
Brugia malayi Nuclear hormone receptor family member nhr-14 0.007 0.1068 0.1311
Loa Loa (eye worm) animal heme peroxidase 0.0033 0.0377 0.0463
Brugia malayi nuclear receptor NHR-67 0.0033 0.0379 0.0465
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0089 0.1427 0.1427
Onchocerca volvulus 0.0033 0.0377 0.0426
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Echinococcus granulosus tyrosine protein kinase Srms 0.0089 0.1427 0.1427
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Echinococcus multilocularis tubulin alpha 0.002 0.013 0.013
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0035 0.0408 0.1555
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0222 0.3888 0.4773
Trypanosoma brucei epsilon tubulin 0.002 0.013 0.0447
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0089 0.1427 0.1427
Brugia malayi Ets-domain containing protein 0.0058 0.085 0.1044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.007 0.1068 0.1311
Loa Loa (eye worm) hypothetical protein 0.007 0.1068 0.1311
Echinococcus granulosus tyrosine protein kinase pr2 0.0089 0.1427 0.1427
Brugia malayi Cytochrome P450 family protein 0.0169 0.2899 0.356
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0162 0.2769 1
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0037 0.0452 0.0555
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0488 0.8835 1
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Toxoplasma gondii STE kinase 0.0089 0.1427 0.5151
Brugia malayi nuclear receptor NHR-88 0.0033 0.0379 0.0465
Brugia malayi tailless protein 0.0033 0.0379 0.0465
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.007 0.1068 0.1068
Echinococcus multilocularis protein kinase 0.0089 0.1427 0.1427
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Loa Loa (eye worm) cytochrome P450 family protein 0.0169 0.2899 0.356
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.007 0.1068 0.1311
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0098 0.1587 0.1587
Brugia malayi Cytochrome P450 family protein 0.0162 0.2769 0.34
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Giardia lamblia Protein 21.1 0.0089 0.1427 0.9985
Plasmodium vivax tubulin epsilon chain, putative 0.002 0.013 0.0494
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0162 0.2769 1
Schistosoma mansoni alpha tubulin 0.0027 0.0256 0.0256
Brugia malayi protein-tyrosine kinase 0.0089 0.1427 0.1751
Leishmania major cytochrome p450-like protein 0.0162 0.2769 0.9552
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0162 0.2769 0.9549
Echinococcus multilocularis beta tubulin 0.002 0.013 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.1427 1
Echinococcus granulosus protein kinase 0.0089 0.1427 0.1427
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0089 0.1427 0.1427
Schistosoma mansoni thyroid hormone receptor 0.007 0.1068 0.1068
Echinococcus granulosus Tubulin beta 2C chain 0.002 0.013 0.013
Entamoeba histolytica tyrosin kinase, putative 0.0089 0.1427 0.8918
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0089 0.1427 0.492
Leishmania major alpha tubulin 0.0027 0.0256 0.0882
Plasmodium vivax tyrosine kinase-like protein, putative 0.0089 0.1427 0.5435
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0256 0.1506
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Brugia malayi alpha-tubulin 0.0027 0.0256 0.0314
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0089 0.1427 0.1427
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0089 0.1427 0.1427
Echinococcus granulosus raf serine:threonine protein kinase 0.0089 0.1427 0.1427
Leishmania major gamma-tubulin 0.002 0.013 0.0447
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0089 0.1427 0.1427
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0451 0.8145 1
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0089 0.1427 0.1427
Onchocerca volvulus Dual oxidase homolog 0.0033 0.0377 0.0426
Loa Loa (eye worm) hypothetical protein 0.0037 0.0452 0.0555
Schistosoma mansoni nuclear receptor 0.0033 0.0379 0.0379
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Plasmodium falciparum tubulin gamma chain 0.002 0.013 0.0494
Giardia lamblia Beta tubulin 0.002 0.013 0.0024
Echinococcus granulosus GPCR family 2 0.007 0.1068 0.1068
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0089 0.1427 0.1427
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0162 0.2769 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.1112 0.1365
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.0101 0.0347
Brugia malayi integrin-linked kinase 0.0089 0.1427 0.1751
Onchocerca volvulus 0.0089 0.1427 0.1615
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0379 0.0379
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.002 0.0127 0.0156
Echinococcus multilocularis activated cdc42 kinase 1 0.0089 0.1427 0.1427
Echinococcus granulosus retinal guanylyl cyclase 2 0.0089 0.1427 0.1427
Echinococcus granulosus regulator of G protein signaling 7 0.0017 0.0086 0.0086
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Echinococcus multilocularis Tubulin beta 2C chain 0.002 0.013 0.013
Toxoplasma gondii hypothetical protein 0.0017 0.0086 0.031
Echinococcus granulosus beta tubulin 0.002 0.013 0.013
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0035 0.0408 0.0501
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0162 0.2769 0.9549
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0037 0.0452 0.0452
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Echinococcus granulosus tubulin alpha chain 0.0027 0.0256 0.0256
Echinococcus granulosus tubulin alpha chain 0.0027 0.0256 0.0256
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Entamoeba histolytica hypothetical protein 0.0098 0.1587 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0089 0.1427 0.1427
Plasmodium falciparum alpha tubulin 2 0.0027 0.0256 0.0974
Leishmania major alpha tubulin 0.0027 0.0256 0.0882
Loa Loa (eye worm) tubulin beta-1 chain 0.002 0.013 0.016
Brugia malayi AMP-binding enzyme family protein 0.0018 0.0101 0.0124
Brugia malayi Death domain containing protein 0.0013 0.00000001373 0.000000016856
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Echinococcus granulosus nuclear receptor 2DBD gamma 0.007 0.1068 0.1068
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Brugia malayi Animal haem peroxidase family protein 0.0033 0.0377 0.0463
Entamoeba histolytica serine/threonine kinase, putative 0.0089 0.1427 0.8918
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.002 0.0127 0.0482
Onchocerca volvulus Huntingtin homolog 0.0094 0.1509 0.1708
Brugia malayi Animal haem peroxidase family protein 0.0033 0.0377 0.0463
Echinococcus multilocularis tyrosine protein kinase csk 0.0089 0.1427 0.1427
Brugia malayi nuclear receptor RXR 0.0033 0.0379 0.0465
Schistosoma mansoni tubulin subunit alpha 0.0027 0.0256 0.0256
Trypanosoma brucei beta tubulin 0.002 0.013 0.0447
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0162 0.2769 1
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0089 0.1427 0.492
Schistosoma mansoni tubulin subunit beta 0.002 0.013 0.013
Loa Loa (eye worm) TK/RYK protein kinase 0.0089 0.1427 0.1751
Schistosoma mansoni transcription factor LCR-F1 0.0098 0.1587 0.1587
Loa Loa (eye worm) nuclear receptor NHR-67 0.0033 0.0379 0.0465
Leishmania major hypothetical protein, conserved 0.0089 0.1427 0.492
Schistosoma mansoni z-protein (S1r protein) 0.0017 0.0086 0.0086
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.007 0.1068 0.1068
Mycobacterium leprae Conserved hypothetical protein 0.0162 0.2769 1
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Trypanosoma brucei protein kinase, putative 0.0089 0.1427 0.492
Leishmania major alpha tubulin 0.0027 0.0256 0.0882
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0089 0.1427 0.1427
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.007 0.1068 0.1068
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Plasmodium vivax tubulin alpha chain, putative 0.0027 0.0256 0.0974
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.007 0.1068 0.1068
Leishmania major alpha tubulin 0.0027 0.0256 0.0882
Loa Loa (eye worm) hypothetical protein 0.0027 0.0257 0.0316
Echinococcus multilocularis tyrosine protein kinase csk 0.0089 0.1427 0.1427
Brugia malayi Furin-like cysteine rich region family protein 0.0089 0.1427 0.1751
Trypanosoma brucei tubulin gamma chain 0.002 0.013 0.0447
Echinococcus multilocularis tyrosine protein kinase Abl 0.0089 0.1427 0.1427
Plasmodium falciparum protein kinase, putative 0.0089 0.1427 0.5435
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0162 0.2769 0.9549
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0162 0.2769 1
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0018 0.0097 0.0119
Schistosoma mansoni hypothetical protein 0.0162 0.2769 0.2769
Loa Loa (eye worm) latrophilin receptor protein 2 0.007 0.1068 0.1311
Brugia malayi hypothetical protein 0.0238 0.4185 0.5137
Leishmania major protein kinase, putative 0.0089 0.1427 0.492
Trichomonas vaginalis tubulin gamma chain, putative 0.002 0.013 0.0593
Loa Loa (eye worm) hypothetical protein 0.007 0.1068 0.1311
Brugia malayi Nuclear hormone receptor family member nhr-40 0.007 0.1068 0.1311
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0089 0.1427 0.1427
Onchocerca volvulus 0.0033 0.0379 0.0429
Schistosoma mansoni hypothetical protein 0.0152 0.2583 0.2583
Echinococcus granulosus nuclear receptor 2DBD gamma 0.007 0.1068 0.1068
Echinococcus multilocularis 0.0162 0.2769 0.2769
Loa Loa (eye worm) tubulin alpha-3 chain 0.0015 0.0048 0.0059
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Schistosoma mansoni protein kinase 0.0089 0.1427 0.1427
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.007 0.1068 0.1311
Loa Loa (eye worm) DIX domain-containing protein 0.0017 0.0086 0.0106
Giardia lamblia Kinase, NEK 0.0089 0.1427 0.9985
Loa Loa (eye worm) TK/Met protein kinase 0.0089 0.1427 0.1751
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Brugia malayi Ets-domain containing protein 0.0058 0.085 0.1044
Brugia malayi ecdysteroid receptor 0.007 0.1068 0.1311
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0073 0.1112 0.1112
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0162 0.2769 0.9549
Entamoeba histolytica tyrosin kinase, putative 0.0089 0.1427 0.8918
Loa Loa (eye worm) hypothetical protein 0.007 0.1068 0.1311
Onchocerca volvulus 0.0017 0.0086 0.0097
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0037 0.0452 0.0555
Loa Loa (eye worm) hypothetical protein 0.0018 0.0101 0.0124
Toxoplasma gondii beta-1 tubulin, putative 0.002 0.013 0.0468
Entamoeba histolytica cysteine surface protein, putative 0.0089 0.1427 0.8918
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0089 0.1427 0.1427
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.1427 1
Schistosoma mansoni tubulin subunit alpha 0.0027 0.0256 0.0256
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.007 0.1068 0.1068
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0089 0.1427 0.1751
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0035 0.0408 0.2611
Schistosoma mansoni DNA topoisomerase type I 0.0154 0.2624 0.2624
Echinococcus multilocularis hypothetical protein 0.0027 0.0256 0.0256
Echinococcus granulosus tyrosine protein kinase 0.0089 0.1427 0.1427
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Trichomonas vaginalis protein kinase atn1, putative 0.0089 0.1427 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.1509 0.1853
Loa Loa (eye worm) serine/threonine protein kinase 0.0089 0.1427 0.1751
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.0452 0.0555
Trypanosoma cruzi protein kinase, putative 0.0089 0.1427 0.492
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0379 0.0379
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Schistosoma mansoni protein kinase 0.0089 0.1427 0.1427
Trichomonas vaginalis tubulin gamma chain, putative 0.002 0.013 0.0593
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0017 0.0086 0.0106
Plasmodium falciparum tyrosine kinase-like protein 0.0089 0.1427 0.5435
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0089 0.1427 0.1427
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Entamoeba histolytica tyrosin kinase, putative 0.0089 0.1427 0.8918
Schistosoma mansoni tyrosine protein kinase 0.0089 0.1427 0.1427
Leishmania major beta tubulin 0.002 0.013 0.0447
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0379 0.0379
Entamoeba histolytica hypothetical protein 0.0089 0.1427 0.8918
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0101 0.0296
Entamoeba histolytica hypothetical protein 0.0089 0.1427 0.8918
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0089 0.1427 0.1427
Brugia malayi Nuclear hormone receptor family member nhr-49 0.007 0.1068 0.1311
Echinococcus multilocularis peroxidasin 0.0033 0.0377 0.0377
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Echinococcus granulosus tubulin alpha 1C chain 0.0027 0.0256 0.0256
Brugia malayi hypothetical protein 0.0033 0.0379 0.0465
Brugia malayi hypothetical protein 0.0037 0.0452 0.0555
Brugia malayi hypothetical protein 0.0033 0.0379 0.0465
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0379 0.0379
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Entamoeba histolytica serine/threonine kinase, putative 0.0089 0.1427 0.8918
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Echinococcus granulosus tubulin epsilon chain 0.002 0.013 0.013
Brugia malayi Raf kinase 0.0089 0.1427 0.1751
Entamoeba histolytica tubulin alpha-1 chain 0.0027 0.0256 0.1042
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.1427 0.1427
Echinococcus multilocularis DNA topoisomerase 1 0.0154 0.2624 0.2624
Leishmania major beta tubulin 0.002 0.013 0.0447
Echinococcus granulosus segment polarity protein dishevelled 0.0017 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.1427 1
Toxoplasma gondii alpha tubulin TUBA1 0.0027 0.0256 0.0923
Schistosoma mansoni hypothetical protein 0.007 0.1068 0.1068
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.007 0.1068 0.1068
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Loa Loa (eye worm) hypothetical protein 0.007 0.1068 0.1311
Entamoeba histolytica hypothetical protein, conserved 0.0089 0.1427 0.8918
Onchocerca volvulus 0.0089 0.1427 0.1615
Echinococcus granulosus Tubulin alpha 1 chain 0.0027 0.0256 0.0256
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0089 0.1427 0.1427
Toxoplasma gondii cytochrome p450 superfamily protein 0.0162 0.2769 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Loa Loa (eye worm) RGC/RGC protein kinase 0.0089 0.1427 0.1751
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.002 0.013 0.0468
Echinococcus multilocularis tyrosine protein kinase shark 0.009 0.1429 0.1429
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Echinococcus multilocularis geminin 0.0293 0.5211 0.5211
Brugia malayi nuclear hormone receptor family member nhr-6 0.0033 0.0379 0.0465
Trypanosoma cruzi importin beta-1 subunit, putative 0.0022 0.0164 0.0564
Schistosoma mansoni tar DNA-binding protein 0.0182 0.3151 0.3151
Trypanosoma brucei beta tubulin 0.002 0.013 0.0447
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Brugia malayi Nuclear hormone receptor family member nhr-1 0.007 0.1068 0.1311
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.007 0.1068 0.1068
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Schistosoma mansoni alpha tubulin 0.0027 0.0256 0.0256
Leishmania major beta tubulin 0.002 0.013 0.0447
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0089 0.1427 0.1751
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.007 0.1068 0.1311
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0162 0.2769 1
Schistosoma mansoni tyrosine kinase 0.009 0.1429 0.1429
Mycobacterium ulcerans acyl-CoA synthetase 0.0018 0.0101 0.0296
Echinococcus granulosus tyrosine protein kinase Src42A 0.0089 0.1427 0.1427
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0089 0.1427 0.1427
Echinococcus multilocularis protein tyrosine kinase 0.0089 0.1427 0.1427
Onchocerca volvulus 0.0238 0.4185 0.4737
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Leishmania major beta tubulin 0.002 0.013 0.0447
Trichomonas vaginalis AGC family protein kinase 0.0089 0.1427 1
Entamoeba histolytica tubulin family protein 0.002 0.013 0.0195
Trichomonas vaginalis protein tyrosine kinase, putative 0.0089 0.1427 1
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0037 0.0452 0.0452
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0162 0.2769 0.9549
Echinococcus granulosus protein tyrosine kinase 0.0089 0.1427 0.1427
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Schistosoma mansoni nuclear receptor 0.0033 0.0379 0.0379
Leishmania major cytochrome p450-like protein 0.0169 0.2899 1
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Leishmania major beta tubulin 0.002 0.013 0.0447
Echinococcus granulosus nuclear factor of activated T cells 5 0.0362 0.6489 0.6489
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0162 0.2769 0.9549
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0106
Trypanosoma cruzi epsilon tubulin, putative 0.002 0.013 0.0447
Brugia malayi Nuclear hormone receptor-like 1 0.007 0.1068 0.1311
Echinococcus granulosus GA binding protein alpha chain 0.0058 0.085 0.085
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0089 0.1427 0.1427
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0035 0.0408 0.1407
Echinococcus granulosus fibroblast growth factor receptor 4 0.0089 0.1427 0.1427
Echinococcus granulosus ephrin type A receptor 4 A 0.0089 0.1427 0.1427
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0089 0.1427 0.1427
Trichomonas vaginalis tubulin epsilon chain, putative 0.002 0.013 0.0593
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Onchocerca volvulus Peroxidase homolog 0.0033 0.0377 0.0426
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Echinococcus multilocularis ephrin type A receptor 4 A 0.0089 0.1427 0.1427
Loa Loa (eye worm) TK protein kinase 0.0089 0.1427 0.1751
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.007 0.1068 0.1068
Brugia malayi AMP-binding enzyme family protein 0.0018 0.0101 0.0124
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0033 0.0379 0.0379
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0033 0.0379 0.0379
Loa Loa (eye worm) TK/FAK protein kinase 0.0089 0.1427 0.1751
Entamoeba histolytica ankyrin repeat protein 0.0089 0.1427 0.8918
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.0115 0.1906 0.6572
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Entamoeba histolytica hypothetical protein 0.0098 0.1587 1
Leishmania major alpha tubulin 0.0027 0.0256 0.0882
Onchocerca volvulus 0.0089 0.1427 0.1615
Brugia malayi nuclear hormone receptor 0.0451 0.8145 1
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0017 0.0086 0.0097
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.0101 0.0347
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0257 0.0887
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Echinococcus multilocularis protein kinase 0.0089 0.1427 0.1427
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0013 0.0002 0.0002
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0089 0.1427 0.1427
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0035 0.0408 0.2067
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Loa Loa (eye worm) TK/ACK protein kinase 0.0089 0.1427 0.1751
Trichomonas vaginalis tubulin epsilon chain, putative 0.0027 0.0256 0.1506
Entamoeba histolytica receptor protein kinase, putative 0.0089 0.1427 0.8918
Brugia malayi Tyrosine-protein kinase PR2 0.0089 0.1427 0.1751
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0089 0.1427 0.1427
Onchocerca volvulus 0.0073 0.1112 0.1259
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0058 0.085 0.1044
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0089 0.1427 0.1427
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.1427 0.1751
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0089 0.1427 0.1427
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0035 0.0408 0.1473
Loa Loa (eye worm) RGC/RGC protein kinase 0.0089 0.1427 0.1751
Toxoplasma gondii HEAT repeat-containing protein 0.0027 0.0257 0.0928
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0162 0.2769 0.9549
Echinococcus multilocularis tubulin alpha 3 chain 0.0027 0.0256 0.0256
Entamoeba histolytica hypothetical protein 0.0089 0.1427 0.8918
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0098 0.1587 0.1587
Onchocerca volvulus 0.0033 0.0379 0.0429
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0379 0.0429
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Giardia lamblia Beta tubulin 0.002 0.013 0.0024
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0089 0.1427 0.1427
Leishmania major cytochrome p450-like protein 0.0162 0.2769 0.9552
Loa Loa (eye worm) alpha-tubulin 0.0027 0.0256 0.0314
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Schistosoma mansoni hypothetical protein 0.007 0.1068 0.1068
Loa Loa (eye worm) TK protein kinase 0.0089 0.1427 0.1751
Leishmania major beta tubulin 0.002 0.013 0.0447
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0089 0.1427 0.1427
Echinococcus granulosus cytochrome P450 2K1 0.0162 0.2769 0.2769
Brugia malayi nuclear receptor RXR 0.0037 0.0452 0.0555
Echinococcus multilocularis tubulin alpha 3 chain 0.0027 0.0256 0.0256
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0089 0.1427 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0162 0.2769 0.9549
Brugia malayi TAR-binding protein 0.0182 0.3151 0.3868
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Trypanosoma brucei beta tubulin 0.002 0.013 0.0447
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0162 0.2769 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.002 0.0127 0.0127
Brugia malayi Nuclear hormone receptor family member nhr-31 0.007 0.1068 0.1311
Echinococcus multilocularis segment polarity protein dishevelled 0.0017 0.0086 0.0086
Echinococcus multilocularis receptor type guanylyl cyclase 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.007 0.1068 0.1311
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0086 0.0086
Plasmodium vivax tubulin alpha chain, putative 0.0027 0.0256 0.0974
Brugia malayi Cytochrome P450 family protein 0.0169 0.2899 0.356
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Echinococcus granulosus alpha tubulin 0.0027 0.0256 0.0256
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0035 0.0408 0.2611
Echinococcus multilocularis tubulin alpha chain 0.0027 0.0256 0.0256
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0089 0.1427 0.1427
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.007 0.1068 0.1068
Brugia malayi steroid hormone receptor 0.007 0.1068 0.1311
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0256 0.1506
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.007 0.1068 0.1068
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Echinococcus multilocularis tubulin alpha chain 0.0027 0.0256 0.0256
Schistosoma mansoni alpha tubulin 0.0027 0.0256 0.0256
Leishmania major beta tubulin 0.002 0.013 0.0447
Onchocerca volvulus Peroxidasin homolog 0.0033 0.0377 0.0426
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Schistosoma mansoni tubulin subunit gamma 0.002 0.013 0.013
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0089 0.1427 0.1427
Plasmodium falciparum importin beta, putative 0.0027 0.0257 0.098
Echinococcus multilocularis tubulin gamma 1 chain 0.002 0.013 0.013
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0162 0.2769 0.9549
Echinococcus granulosus beta tubulin 0.002 0.013 0.013
Schistosoma mansoni dishevelled 0.0017 0.0086 0.0086
Brugia malayi hypothetical protein 0.0089 0.1427 0.1751
Loa Loa (eye worm) hypothetical protein 0.005 0.0692 0.085
Schistosoma mansoni DNA topoisomerase type I 0.0115 0.1906 0.1906
Echinococcus multilocularis tar DNA binding protein 0.0182 0.3151 0.3151
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Schistosoma mansoni Tr4/Tr2 (homologue) 0.007 0.1068 0.1068
Trichomonas vaginalis ran, putative 0.002 0.0127 0.057
Entamoeba histolytica tubulin alpha chain, putative 0.0027 0.0256 0.1042
Entamoeba histolytica hypothetical protein 0.0089 0.1427 0.8918
Echinococcus multilocularis tubulin beta 1 chain 0.002 0.013 0.013
Plasmodium vivax tubulin beta chain, putative 0.002 0.013 0.0494
Echinococcus granulosus Tubulin beta 2C chain 0.002 0.013 0.013
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0013 0.00000001373 0.00000001373
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.007 0.1068 0.1068
Entamoeba histolytica hypothetical protein 0.0089 0.1427 0.8918
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Brugia malayi hypothetical protein 0.0094 0.1509 0.1853
Echinococcus granulosus snurportin 1 0.0284 0.5039 0.5039
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.007 0.1068 0.1311
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0162 0.2769 0.9549
Leishmania major epsilon tubulin, putative 0.002 0.013 0.0447
Schistosoma mansoni steroid hormone receptor ad4bp 0.007 0.1068 0.1068
Brugia malayi tubulin alpha chain - mouse 0.0027 0.0256 0.0314
Schistosoma mansoni dishevelled 0.0017 0.0086 0.0086
Brugia malayi RNA, U transporter 1 0.0076 0.1169 0.1435
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0106
Onchocerca volvulus 0.0089 0.1427 0.1615
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0162 0.2769 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0089 0.1427 0.1751
Echinococcus multilocularis Tubulin beta 2C chain 0.002 0.013 0.013
Entamoeba histolytica hypothetical protein 0.0089 0.1427 0.8918
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.1427 1
Echinococcus granulosus tubulin beta 1 chain 0.002 0.013 0.013
Loa Loa (eye worm) TK protein kinase 0.0089 0.1427 0.1751
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0018 0.0101 0.0364
Echinococcus multilocularis peroxisome assembly protein 26 0.0027 0.0256 0.0256
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0162 0.2769 1
Echinococcus multilocularis Tubulin beta 2C chain 0.002 0.013 0.013
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Schistosoma mansoni protein kinase 0.0089 0.1427 0.1427
Echinococcus multilocularis Ankyrin 0.0013 0.0002 0.0002
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0257 0.0887
Loa Loa (eye worm) cytochrome P450 family protein 0.0169 0.2899 0.356
Echinococcus granulosus activated cdc42 kinase 1 0.0089 0.1427 0.1427
Onchocerca volvulus Huntingtin homolog 0.0094 0.1509 0.1708
Echinococcus multilocularis tyrosine protein kinase Srms 0.0089 0.1427 0.1427
Trichomonas vaginalis tubulin epsilon chain, putative 0.002 0.013 0.0593
Onchocerca volvulus 0.0089 0.1427 0.1615
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0089 0.1427 0.1427
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.007 0.1068 0.1068
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Schistosoma mansoni protein kinase 0.009 0.1429 0.1429
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.007 0.1068 0.1311
Echinococcus granulosus Tubulin beta 2C chain 0.002 0.013 0.013
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0089 0.1427 0.1751
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0089 0.1427 0.1427
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Entamoeba histolytica hypothetical protein 0.0098 0.1587 1
Schistosoma mansoni tar DNA-binding protein 0.0182 0.3151 0.3151
Echinococcus granulosus importin subunit beta 1 0.0027 0.0257 0.0257
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0162 0.2769 1
Loa Loa (eye worm) tubulin alpha chain 0.0027 0.0256 0.0314
Schistosoma mansoni importin beta-1 0.0027 0.0257 0.0257
Onchocerca volvulus 0.0089 0.1427 0.1615
Brugia malayi nuclear hormone receptor 0.007 0.1068 0.1311
Schistosoma mansoni hypothetical protein 0.0293 0.5211 0.5211
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0089 0.1427 0.1751
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Trichomonas vaginalis TK family protein kinase 0.0089 0.1427 1
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0162 0.2769 1
Onchocerca volvulus 0.0089 0.1427 0.1615
Schistosoma mansoni hypothetical protein 0.007 0.1068 0.1068
Echinococcus granulosus tubulin alpha chain 0.0027 0.0256 0.0256
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Echinococcus multilocularis FL cytokine receptor 0.0089 0.1427 0.1427
Leishmania major alpha tubulin 0.0027 0.0256 0.0882
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.0039 0.0482 0.1662
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0027 0.0256 0.1506
Leishmania major alpha tubulin 0.0027 0.0256 0.0882
Loa Loa (eye worm) hypothetical protein 0.0073 0.1112 0.1365
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0379 0.0379
Schistosoma mansoni protein kinase 0.009 0.1429 0.1429
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0019
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0162 0.2769 0.9549
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.007 0.1068 0.1068
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0035 0.0408 0.0408
Loa Loa (eye worm) TK protein kinase 0.0089 0.1427 0.1751
Treponema pallidum sodium- and chloride- dependent transporter 0.0073 0.1112 0.5
Echinococcus granulosus natriuretic peptide receptor 1 0.0089 0.1427 0.1427
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0089 0.1427 0.1427
Trypanosoma brucei epsilon tubulin 0.002 0.013 0.0447
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Trichomonas vaginalis tubulin, putative 0.002 0.013 0.0593
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Loa Loa (eye worm) cytochrome P450 family protein 0.0162 0.2769 0.34
Schistosoma mansoni peroxidasin 0.0033 0.0377 0.0377
Loa Loa (eye worm) BEN-1 protein 0.002 0.013 0.016
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Echinococcus granulosus tar DNA binding protein 0.0182 0.3151 0.3151
Leishmania major alpha tubulin 0.0027 0.0256 0.0882
Echinococcus granulosus tubulin alpha 1C chain 0.0027 0.0256 0.0256
Brugia malayi Peroxidasin 0.0033 0.0377 0.0463
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0353 0.6323 0.7763
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0089 0.1427 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0152 0.2583 0.3171
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0089 0.1427 0.492
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.007 0.1068 0.1311
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Brugia malayi RNA recognition motif domain containing protein 0.0182 0.3151 0.3868
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0162 0.2769 1
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Onchocerca volvulus 0.0089 0.1427 0.1615
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Plasmodium vivax importin-beta 2, putative 0.0027 0.0257 0.098
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Brugia malayi hypothetical protein 0.0098 0.1587 0.1949
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.0059
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0089 0.1427 0.5151
Schistosoma mansoni tubulin subunit alpha 0.0027 0.0256 0.0256
Echinococcus multilocularis regulator of G protein signaling 7 0.0017 0.0086 0.0086
Echinococcus multilocularis heat shock protein 70 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0017 0.0086 0.0106
Onchocerca volvulus 0.0089 0.1427 0.1615
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0073 0.1112 0.1365
Echinococcus granulosus tyrosine kinase 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0019
Echinococcus multilocularis tyrosine kinase 0.0089 0.1427 0.1427
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0089 0.1427 0.1751
Echinococcus multilocularis importin subunit beta 1 0.0027 0.0257 0.0257
Echinococcus multilocularis raf serine:threonine protein kinase 0.0089 0.1427 0.1427
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0089 0.1427 0.1751
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0089 0.1427 0.1427
Loa Loa (eye worm) tubulin alpha chain 0.0027 0.0256 0.0314
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Brugia malayi Receptor family ligand binding region containing protein 0.0089 0.1427 0.1751
Brugia malayi ecdysone receptor 0.0033 0.0379 0.0465
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Onchocerca volvulus Protein ultraspiracle homolog 0.007 0.1068 0.1209
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.007 0.1068 0.1068
Leishmania major beta tubulin 0.002 0.013 0.0447
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Echinococcus multilocularis transfer RNA-Thr 0.0089 0.1427 0.1427
Echinococcus granulosus thyroid hormone receptor alpha 0.0033 0.0379 0.0379
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.007 0.1068 0.1068
Trypanosoma brucei alpha tubulin 0.0027 0.0256 0.0882
Echinococcus granulosus Tubulin beta 2C chain 0.002 0.013 0.013
Schistosoma mansoni ankyrin 23/unc44 0.0013 0.00000001373 0.00000001373
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0379 0.0465
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.0452 0.0555
Leishmania major importin beta-1 subunit, putative 0.0022 0.0164 0.0564
Echinococcus granulosus regulator of G protein signaling 7 0.0017 0.0086 0.0086
Loa Loa (eye worm) TK/ABL protein kinase 0.0089 0.1427 0.1751
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Loa Loa (eye worm) TAR-binding protein 0.0182 0.3151 0.3868
Onchocerca volvulus 0.0033 0.0377 0.0426
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0169 0.2899 1
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0353 0.6323 0.7157
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0089 0.1427 0.8918
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.1427 1
Leishmania major protein kinase, putative 0.0089 0.1427 0.492
Echinococcus granulosus Pleckstrin G protein interacting region 0.0017 0.0086 0.0086
Echinococcus multilocularis Tubulin alpha 1 chain 0.0027 0.0256 0.0256
Brugia malayi Nuclear hormone receptor family member nhr-19 0.007 0.1068 0.1311
Schistosoma mansoni zinc finger protein 0.0033 0.0379 0.0379
Schistosoma mansoni tar DNA-binding protein 0.0182 0.3151 0.3151
Trypanosoma cruzi beta tubulin, putative 0.002 0.013 0.0447
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Brugia malayi N-terminal motif family protein 0.0353 0.6323 0.7763
Brugia malayi Protein kinase domain containing protein 0.0013 0.00000001373 0.000000016856
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0089 0.1427 0.1751
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Loa Loa (eye worm) TK/DDR protein kinase 0.0089 0.1427 0.1751
Leishmania major beta tubulin 0.002 0.013 0.0447
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Plasmodium falciparum tubulin epsilon chain, putative 0.002 0.013 0.0494
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0014 0.0016 0.5
Loa Loa (eye worm) tubulin alpha 2 0.0018 0.0097 0.0119
Echinococcus multilocularis tubulin, beta 4A class IVa 0.002 0.013 0.013
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0089 0.1427 0.1427
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0018 0.0101 0.0296
Echinococcus granulosus retinal guanylyl cyclase 2 0.0089 0.1427 0.1427
Echinococcus granulosus activated cdc42 kinase 1 0.0089 0.1427 0.1427
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.1427 0.1427
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0002 0.0006
Plasmodium falciparum protein kinase, putative 0.0089 0.1427 0.5435
Echinococcus multilocularis tyrosine protein kinase 0.0089 0.1427 0.1427
Schistosoma mansoni cytochrome P450 0.0162 0.2769 0.2769
Entamoeba histolytica tubulin family protein 0.002 0.013 0.0195
Echinococcus granulosus tyrosine protein kinase csk 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Echinococcus multilocularis kinase suppressor of Ras 1 0.0089 0.1427 0.1427
Brugia malayi Tubulin gamma chain 0.002 0.013 0.016
Loa Loa (eye worm) SRC-1 0.0089 0.1427 0.1751
Brugia malayi hypothetical protein 0.0089 0.1427 0.1751
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0106
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0089 0.1427 0.1427
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0222 0.3888 0.4773
Loa Loa (eye worm) fli-1 protein 0.0178 0.3063 0.376
Toxoplasma gondii alpha-tubulin I, putative 0.0027 0.0256 0.0923
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0379 0.0379
Plasmodium vivax protein kinase, putative 0.0089 0.1427 0.5435
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0379 0.0379
Schistosoma mansoni gabp alpha 0.0058 0.085 0.085
Schistosoma mansoni protein kinase 0.0089 0.1427 0.1427
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0089 0.1427 0.1615
Brugia malayi Tubulin alpha-2 chain 0.0027 0.0256 0.0314
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0089 0.1427 0.1751
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0089 0.1427 0.1427
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0379 0.0379
Loa Loa (eye worm) blistered cuticle protein 3 0.0033 0.0377 0.0463
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Brugia malayi regulator of G-protein signaling egl-10 0.0017 0.0086 0.0106
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0002 0.0006
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0033 0.0379 0.0379
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.002 0.0127 0.0482
Echinococcus granulosus tubulin alpha chain 0.0027 0.0256 0.0256
Brugia malayi hypothetical protein 0.0037 0.0452 0.0555
Loa Loa (eye worm) beta-tubulin 0.002 0.013 0.016
Entamoeba histolytica tubulin gamma chain 0.002 0.013 0.0195
Echinococcus granulosus ecdysone induced protein 78C 0.007 0.1068 0.1068
Echinococcus multilocularis snurportin 1 0.0284 0.5039 0.5039
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0164 0.0838
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Schistosoma mansoni tubulin subunit beta 0.002 0.013 0.013
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0089 0.1427 0.1427
Leishmania major beta tubulin 0.002 0.013 0.0447
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Loa Loa (eye worm) tubulin alpha-2 chain 0.0027 0.0256 0.0314
Entamoeba histolytica hypothetical protein 0.0089 0.1427 0.8918
Giardia lamblia Kinase, NEK 0.009 0.1429 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0002 0.0006
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0035 0.0408 0.0408
Echinococcus multilocularis GA binding protein alpha chain 0.0058 0.085 0.085
Leishmania major beta tubulin 0.002 0.013 0.0447
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0035 0.0408 0.0501
Schistosoma mansoni tubulin subunit beta 0.002 0.013 0.013
Loa Loa (eye worm) TK/EPH protein kinase 0.0089 0.1427 0.1751
Echinococcus multilocularis tyrosine protein kinase Blk 0.0089 0.1427 0.1427
Schistosoma mansoni RAR-like nuclear receptor 0.007 0.1068 0.1068
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0162 0.2769 0.9549
Onchocerca volvulus 0.0089 0.1427 0.1615
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Echinococcus granulosus tyrosine kinase 0.0089 0.1427 0.1427
Plasmodium vivax topoisomerase I, putative 0.0154 0.2624 1
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0182 0.3151 0.3868
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0162 0.2769 0.9552
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Echinococcus multilocularis Tubulin alpha 1 chain 0.0027 0.0256 0.0256
Echinococcus granulosus tubulin alpha 3 chain 0.0027 0.0256 0.0256
Echinococcus granulosus Tubulin beta 2C chain 0.002 0.013 0.013
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Echinococcus granulosus tyrosine protein kinase csk 0.0089 0.1427 0.1427
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0089 0.1427 0.492
Schistosoma mansoni ran 0.002 0.0127 0.0127
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0089 0.1427 1
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0017 0.0086 0.0086
Brugia malayi Calcitonin receptor-like protein seb-1 0.0222 0.3888 0.4773
Brugia malayi Guanylyl cyclase protein 23 0.0089 0.1427 0.1751
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Schistosoma mansoni hypothetical protein 0.0284 0.5039 0.5039
Loa Loa (eye worm) DR-78 0.0033 0.0379 0.0465
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.002 0.0127 0.0437
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0037 0.0452 0.0452
Onchocerca volvulus 0.0089 0.1427 0.1615
Echinococcus granulosus kinase suppressor of Ras 1 0.0089 0.1427 0.1427
Toxoplasma gondii protein kinase 0.0089 0.1427 0.5151
Brugia malayi Tubulin alpha chain 0.0027 0.0256 0.0314
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Echinococcus granulosus nuclear receptor nhr 48 0.0033 0.0379 0.0379
Loa Loa (eye worm) TK protein kinase 0.0089 0.1427 0.1751
Brugia malayi Fli-1 protein 0.0178 0.3063 0.376
Echinococcus multilocularis tubulin subunit TubB 0.0027 0.0256 0.0256
Entamoeba histolytica hypothetical protein 0.0089 0.1427 0.8918
Schistosoma mansoni thyroid hormone receptor 0.007 0.1068 0.1068
Schistosoma mansoni ets-related 0.0178 0.3063 0.3063
Schistosoma mansoni tubulin subunit epsilon 0.002 0.013 0.013
Brugia malayi hypothetical protein 0.0033 0.0377 0.0463
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Echinococcus multilocularis tyrosine protein kinase pr2 0.0089 0.1427 0.1427
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0033 0.0379 0.0379
Brugia malayi bone morphogenetic protein type 1 receptor 0.0089 0.1427 0.1751
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.0115 0.1906 0.6572
Leishmania major alpha tubulin 0.0027 0.0256 0.0882
Echinococcus granulosus c src tyrosine kinase 0.0089 0.1427 0.1427
Brugia malayi SH2 domain containing protein 0.0089 0.1427 0.1751
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.007 0.1068 0.1068
Echinococcus multilocularis beta tubulin 0.002 0.013 0.013
Entamoeba histolytica hypothetical protein 0.0098 0.1587 1
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Mycobacterium ulcerans hypothetical protein 0.0018 0.0101 0.0296
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Entamoeba histolytica tyrosin kinase, putative 0.0089 0.1427 0.8918
Trichomonas vaginalis importin beta-1, putative 0.0022 0.0164 0.0838
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0089 0.1427 0.1751
Schistosoma mansoni ephrin receptor 0.0089 0.1427 0.1427
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Giardia lamblia Kinase 0.0089 0.1427 0.9985
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0089 0.1427 0.1427
Echinococcus granulosus geminin 0.0293 0.5211 0.5211
Schistosoma mansoni hypothetical protein 0.007 0.1068 0.1068
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0035 0.0408 0.1407
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0014 0.0016 0.0055
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0017 0.0086 0.0106
Trypanosoma brucei epsilon tubulin 0.002 0.013 0.0447
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Plasmodium falciparum protein kinase, putative 0.0089 0.1427 0.5435
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0035 0.0408 0.0501
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.1427 1
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0162 0.2769 0.9549
Echinococcus granulosus tubulin alpha 3 chain 0.0027 0.0256 0.0256
Giardia lamblia Gamma tubulin 0.002 0.013 0.0024
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.002 0.0127 0.0437
Loa Loa (eye worm) hypothetical protein 0.0037 0.0452 0.0555
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0089 0.1427 1
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.002 0.0127 0.0457
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Echinococcus granulosus tyrosine protein kinase ABL1 0.0089 0.1427 0.1427
Echinococcus multilocularis integrin linked protein kinase 0.0089 0.1427 0.1427
Echinococcus multilocularis epidermal growth factor receptor 0.0089 0.1427 0.1427
Trypanosoma cruzi cytochrome P450, putative 0.0169 0.2899 1
Schistosoma mansoni protein tyrosine kinase 0.0089 0.1427 0.1427
Leishmania major DNA topoisomerase IB, large subunit 0.0115 0.1906 0.6572
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0089 0.1427 0.1751
Brugia malayi Nuclear hormone receptor family member nhr-19 0.007 0.1068 0.1311
Brugia malayi nuclear receptor NHR-88 0.007 0.1068 0.1311
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Trypanosoma brucei cytochrome P450, putative 0.0169 0.2899 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0089 0.1427 0.1427
Onchocerca volvulus 0.0018 0.0101 0.0114
Plasmodium vivax acyl-CoA synthetase, putative 0.0014 0.0016 0.0058
Echinococcus multilocularis microtubule associated protein 2 0.0551 1 1
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Echinococcus granulosus DNA topoisomerase 1 0.0154 0.2624 0.2624
Mycobacterium ulcerans acyl-CoA synthetase 0.0018 0.0101 0.0296
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0379 0.0465
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.007 0.1068 0.1068
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Echinococcus multilocularis protein KINase family member (kin 25) 0.0089 0.1427 0.1427
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0162 0.2769 1
Loa Loa (eye worm) tubulin alpha 2 0.0018 0.0097 0.0119
Plasmodium falciparum alpha tubulin 1 0.0027 0.0256 0.0974
Trypanosoma brucei alpha tubulin 0.0027 0.0256 0.0882
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.1427 0.1427
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Giardia lamblia Beta tubulin 0.002 0.013 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0256 0.0314
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0162 0.2769 0.9552
Schistosoma mansoni protein kinase 0.0089 0.1427 0.1427
Onchocerca volvulus Chorion peroxidase homolog 0.0033 0.0377 0.0426
Entamoeba histolytica hypothetical protein 0.0089 0.1427 0.8918
Echinococcus multilocularis GPCR, family 2 0.007 0.1068 0.1068
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Onchocerca volvulus 0.0089 0.1427 0.1615
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Onchocerca volvulus 0.0089 0.1427 0.1615
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Brugia malayi Blistered cuticle protein 3 0.0033 0.0377 0.0463
Schistosoma mansoni coup transcription factor 0.007 0.1068 0.1068
Loa Loa (eye worm) TK protein kinase 0.0089 0.1427 0.1751
Brugia malayi Tubulin beta-1 chain 0.002 0.013 0.016
Echinococcus multilocularis tubulin subunit beta 0.002 0.013 0.013
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0256 0.1506
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0035 0.0408 0.0408
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Echinococcus multilocularis Tubulin beta 2C chain 0.002 0.013 0.013
Echinococcus granulosus integrin linked protein kinase 0.0089 0.1427 0.1427
Brugia malayi Animal haem peroxidase family protein 0.0033 0.0377 0.0463
Loa Loa (eye worm) TK protein kinase 0.0089 0.1427 0.1751
Loa Loa (eye worm) hypothetical protein 0.007 0.1068 0.1311
Plasmodium falciparum tyrosine kinase-like protein 0.0089 0.1427 0.5435
Loa Loa (eye worm) CYP4Cod1 0.0169 0.2899 0.356
Loa Loa (eye worm) hypothetical protein 0.007 0.1068 0.1311
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0089 0.1427 0.1427
Echinococcus granulosus segment polarity protein dishevelled 0.0017 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0089 0.1427 0.1427
Entamoeba histolytica serine/threonine kinase, putative 0.0089 0.1427 0.8918
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0089 0.1427 0.1427
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0037 0.0452 0.0452
Schistosoma mansoni dep domain containing protein 0.0017 0.0086 0.0086
Echinococcus multilocularis activin receptor type 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.007 0.1068 0.1311
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0089 0.1427 0.1751
Echinococcus multilocularis tyrosine protein kinase csk 0.0089 0.1427 0.1427
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0089 0.1427 0.1751
Schistosoma mansoni protein kinase 0.0089 0.1427 0.1427
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0162 0.2769 0.9549
Echinococcus granulosus serotonin transporter 0.0073 0.1112 0.1112
Mycobacterium ulcerans acyl-CoA synthetase 0.0018 0.0101 0.0296
Loa Loa (eye worm) TK/EGFR protein kinase 0.0089 0.1427 0.1751
Brugia malayi SRC-1 0.0089 0.1427 0.1751
Loa Loa (eye worm) TK/ROR protein kinase 0.0089 0.1427 0.1751
Echinococcus granulosus Ankyrin 0.0013 0.0002 0.0002
Echinococcus multilocularis tyrosine kinase 0.0089 0.1427 0.1427
Brugia malayi photoreceptor-specific nuclear receptor 0.007 0.1068 0.1311
Echinococcus granulosus epidermal growth factor receptor 0.0089 0.1427 0.1427
Schistosoma mansoni nuclear receptor nhr-48 0.0033 0.0379 0.0379
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Loa Loa (eye worm) DNA topoisomerase I 0.0154 0.2624 0.3222
Echinococcus granulosus Tubulin alpha 1 chain 0.0027 0.0256 0.0256
Brugia malayi conserved hypotetical protein 0.0033 0.0379 0.0465
Echinococcus multilocularis tyrosine protein kinase csk 0.0089 0.1427 0.1427
Echinococcus granulosus receptor type guanylyl cyclase 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Echinococcus multilocularis insulin receptor 0.0089 0.1427 0.1427
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Echinococcus granulosus tubulin alpha 0.002 0.013 0.013
Echinococcus granulosus peroxidasin 0.0033 0.0377 0.0377
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0035 0.0408 0.1407
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.002 0.0127 0.0156
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0037 0.0452 0.0555
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.007 0.1068 0.1311
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.0089 0.1427 0.5435
Loa Loa (eye worm) hypothetical protein 0.0222 0.3888 0.4773
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Trichomonas vaginalis tubulin epsilon chain, putative 0.0027 0.0256 0.1506
Loa Loa (eye worm) TK protein kinase 0.0089 0.1427 0.1751
Loa Loa (eye worm) RNA binding protein 0.0182 0.3151 0.3868
Echinococcus granulosus tubulin beta 4A class IVa 0.002 0.013 0.013
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Brugia malayi Animal haem peroxidase family protein 0.0033 0.0377 0.0463
Echinococcus granulosus tyrosine protein kinase Fyn 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0089 0.1427 0.1751
Brugia malayi nuclear hormone receptor family member odr-7 0.0033 0.0379 0.0465
Loa Loa (eye worm) TK/ALK protein kinase 0.0089 0.1427 0.1751
Leishmania major alpha tubulin 0.0027 0.0256 0.0882
Entamoeba histolytica serine/threonine kinase, putative 0.0089 0.1427 0.8918
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0089 0.1427 0.1427
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Onchocerca volvulus 0.0089 0.1427 0.1615
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0162 0.2769 1
Onchocerca volvulus 0.0089 0.1427 0.1615
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0162 0.2769 1
Echinococcus granulosus insulin receptor 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0379 0.0429
Echinococcus granulosus tyrosine protein kinase Src64B 0.0089 0.1427 0.1427
Echinococcus multilocularis serotonin transporter 0.0073 0.1112 0.1112
Toxoplasma gondii beta tubulin 0.002 0.013 0.0468
Brugia malayi beta-tubulin, identical 0.002 0.013 0.016
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Onchocerca volvulus Tyrosine kinase homolog 0.0089 0.1427 0.1615
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Entamoeba histolytica serine/threonine kinase, putative 0.0089 0.1427 0.8918
Echinococcus granulosus FTZ F1 alpha 0.007 0.1068 0.1068
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0089 0.1427 0.5151
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0256 0.1506
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0089 0.1427 0.8918
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.007 0.1068 0.1068
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Entamoeba histolytica hypothetical protein 0.0089 0.1427 0.8918
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Entamoeba histolytica hypothetical protein 0.0022 0.0164 0.0423
Echinococcus granulosus Tubulin alpha 1 chain 0.0027 0.0256 0.0256
Brugia malayi Uncoordinated protein 44 0.0013 0.00000001373 0.000000016856
Trypanosoma cruzi epsilon tubulin, putative 0.002 0.013 0.0447
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0162 0.2769 0.9549
Loa Loa (eye worm) RGC/RGC protein kinase 0.0089 0.1427 0.1751
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0017 0.0086 0.0086
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0089 0.1427 0.1427
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0162 0.2769 0.9552
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.0101 0.0347
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Loa Loa (eye worm) hypothetical protein 0.0037 0.0452 0.0555
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0162 0.2769 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0101 0.0124
Echinococcus multilocularis tubulin alpha 1C chain 0.0027 0.0256 0.0256
Echinococcus granulosus epidermal growth factor receptor 0.0089 0.1427 0.1427
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Echinococcus multilocularis Tubulin beta 2C chain 0.002 0.013 0.013
Toxoplasma gondii beta-tubulin, putative 0.002 0.013 0.0468
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0089 0.1427 0.8918
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0089 0.1427 0.1427
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Echinococcus multilocularis c src tyrosine kinase 0.0089 0.1427 0.1427
Loa Loa (eye worm) animal heme peroxidase 0.0033 0.0377 0.0463
Brugia malayi DNA topoisomerase I 0.0154 0.2624 0.3222
Trichomonas vaginalis tubulin alpha chain, putative 0.002 0.013 0.0593
Schistosoma mansoni ephrin receptor 0.0089 0.1427 0.1427
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Giardia lamblia Alpha-tubulin 0.0027 0.0256 0.0991
Schistosoma mansoni serine/threonine RGC 0.0089 0.1427 0.1427
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0162 0.2769 1
Echinococcus granulosus tyrosine protein kinase Lyn 0.0089 0.1427 0.1427
Giardia lamblia Alpha-tubulin 0.0027 0.0256 0.0991
Loa Loa (eye worm) serotonin transporter b 0.0073 0.1112 0.1365
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Brugia malayi C-terminal src kinase protein 1 0.0089 0.1427 0.1751
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0089 0.1427 0.1427
Brugia malayi latrophilin 2 splice variant baaae 0.0152 0.2583 0.3171
Brugia malayi SH2 domain containing protein 0.0089 0.1427 0.1751
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Leishmania major alpha tubulin 0.0027 0.0256 0.0882
Plasmodium falciparum topoisomerase I 0.0154 0.2624 1
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0162 0.2769 0.9552
Onchocerca volvulus Peroxidase homolog 0.0033 0.0377 0.0426
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0089 0.1427 0.1751
Echinococcus multilocularis Tubulin alpha 1 chain 0.0027 0.0256 0.0256
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0018 0.0097 0.035
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0018 0.0101 0.0296
Brugia malayi orphan nuclear receptor NR2E1 0.0033 0.0379 0.0465
Echinococcus multilocularis tyrosine protein kinase HCK 0.0089 0.1427 0.1427
Schistosoma mansoni retinoic acid receptor RXR 0.007 0.1068 0.1068
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.007 0.1068 0.1068
Echinococcus granulosus tyrosine protein kinase csk 0.0089 0.1427 0.1427
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0162 0.2769 0.9549
Leishmania major DNA topoisomerase type IB small subunit 0.0039 0.0482 0.1662
Trypanosoma cruzi cytochrome P450, putative 0.0169 0.2899 1
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0035 0.0408 0.1407
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Toxoplasma gondii DNA topoisomerase I, putative 0.0154 0.2624 0.9476
Plasmodium vivax tubulin gamma chain, putative 0.002 0.013 0.0494
Trypanosoma brucei Flagellum attachment zone protein 20 0.0089 0.1427 0.492
Entamoeba histolytica hypothetical protein 0.0089 0.1427 0.8918
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0162 0.2769 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0089 0.1427 0.1427
Onchocerca volvulus Bile acid receptor homolog 0.007 0.1068 0.1209
Leishmania major beta tubulin 0.002 0.013 0.0447
Schistosoma mansoni hypothetical protein 0.0098 0.1587 0.1587
Entamoeba histolytica Ran family GTPase 0.002 0.0127 0.0174
Schistosoma mansoni tar DNA-binding protein 0.0182 0.3151 0.3151
Leishmania major beta tubulin 0.002 0.013 0.0447
Loa Loa (eye worm) steroid hormone receptor 0.007 0.1068 0.1311
Loa Loa (eye worm) BEN-1 protein 0.002 0.013 0.016
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Echinococcus granulosus tyrosine kinase 0.0089 0.1427 0.1427
Schistosoma mansoni ran 0.002 0.0127 0.0127
Trypanosoma brucei Pseudokinase, putative 0.0089 0.1427 0.492
Brugia malayi RNA binding protein 0.0182 0.3151 0.3868
Brugia malayi Steroid receptor seven-up type 2 0.007 0.1068 0.1311
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0089 0.1427 0.1615
Schistosoma mansoni protein kinase 0.0089 0.1427 0.1427
Echinococcus multilocularis ecdysone induced protein 78C 0.007 0.1068 0.1068
Trypanosoma cruzi tubulin gamma chain 0.002 0.013 0.0447
Echinococcus multilocularis tubulin alpha 1C chain 0.0027 0.0256 0.0256
Schistosoma mansoni retinoid-x-receptor (RXR) 0.007 0.1068 0.1068
Brugia malayi Latrophilin receptor protein 2 0.007 0.1068 0.1311
Brugia malayi tubulin alpha-2 chain 0.0027 0.0256 0.0314
Schistosoma mansoni tubulin subunit beta 0.002 0.013 0.013
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Echinococcus multilocularis tubulin epsilon chain 0.002 0.013 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.1427 1
Schistosoma mansoni hypothetical protein 0.0293 0.5211 0.5211
Loa Loa (eye worm) TK protein kinase 0.0089 0.1427 0.1751
Brugia malayi cytochrome P450 0.0162 0.2769 0.34
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Brugia malayi hypothetical protein 0.0089 0.1427 0.1751
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Leishmania major beta tubulin 0.002 0.013 0.0447
Brugia malayi Tyrosine-protein kinase abl-1 0.0089 0.1427 0.1751
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.007 0.1068 0.1311
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.002 0.0127 0.0437
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0284 0.5039 0.6186
Brugia malayi Animal haem peroxidase family protein 0.0033 0.0377 0.0463
Echinococcus multilocularis regulator of G protein signaling 7 0.0017 0.0086 0.0086
Trichomonas vaginalis tubulin gamma chain, putative 0.002 0.013 0.0593
Loa Loa (eye worm) protein kinase domain-containing protein 0.0089 0.1427 0.1751
Echinococcus multilocularis tubulin alpha chain 0.0027 0.0256 0.0256
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Entamoeba histolytica ankyrin repeat protein 0.0089 0.1427 0.8918
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Schistosoma mansoni peroxidasin 0.0033 0.0377 0.0377
Loa Loa (eye worm) tubulin beta chain 0.002 0.013 0.016
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Echinococcus granulosus tyrosine protein kinase shark 0.009 0.1429 0.1429
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0073 0.1112 0.1365
Loa Loa (eye worm) animal heme peroxidase 0.0033 0.0377 0.0463
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0162 0.2769 0.9549
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Echinococcus multilocularis GTP binding nuclear protein Ran 0.002 0.0127 0.0127
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0256 0.1506
Echinococcus granulosus tyrosine protein kinase Blk 0.0089 0.1427 0.1427
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Echinococcus granulosus activin receptor type 0.0089 0.1427 0.1427
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0162 0.2769 0.9549
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Trypanosoma brucei alpha tubulin 0.0027 0.0256 0.0882
Trypanosoma brucei beta tubulin 0.002 0.013 0.0447
Echinococcus multilocularis segment polarity protein dishevelled 0.0017 0.0086 0.0086
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0362 0.6489 0.6489
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0035 0.0408 0.1555
Brugia malayi Nuclear hormone receptor family member nhr-41 0.007 0.1068 0.1311
Brugia malayi AMP-binding enzyme family protein 0.0018 0.0101 0.0124
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0089 0.1427 0.1427
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0162 0.2769 0.9552
Toxoplasma gondii protein kinase domain-containing protein 0.0089 0.1427 0.5151
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0101 0.0364
Echinococcus multilocularis tubulin alpha chain 0.0027 0.0256 0.0256
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Loa Loa (eye worm) hypothetical protein 0.0033 0.0377 0.0463
Onchocerca volvulus Peroxidasin homolog 0.0033 0.0377 0.0426
Trichomonas vaginalis STE family protein kinase 0.0089 0.1427 1
Schistosoma mansoni tubulin subunit beta 0.002 0.013 0.013
Plasmodium falciparum tubulin beta chain 0.002 0.013 0.0494
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0164 0.0838
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0019
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0089 0.1427 0.1427
Loa Loa (eye worm) tubulin gamma chain 0.002 0.013 0.016
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0089 0.1427 0.5151
Schistosoma mansoni tar DNA-binding protein 0.0182 0.3151 0.3151
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0162 0.2769 1
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0256 0.1506
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Trypanosoma cruzi protein kinase, putative 0.0089 0.1427 0.492
Leishmania major beta tubulin 0.002 0.013 0.0447
Echinococcus granulosus tubulin alpha chain 0.0027 0.0256 0.0256
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0089 0.1427 0.1427
Echinococcus multilocularis epidermal growth factor receptor 0.0089 0.1427 0.1427
Brugia malayi Importin beta-1 subunit 0.0027 0.0257 0.0316
Leishmania major beta tubulin 0.002 0.013 0.0447
Loa Loa (eye worm) hypothetical protein 0.0018 0.0097 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0033 0.0379 0.0379
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Leishmania major alpha tubulin 0.0027 0.0256 0.0882
Entamoeba histolytica receptor protein kinase, putative 0.0089 0.1427 0.8918
Loa Loa (eye worm) nuclear hormone receptor 0.0033 0.0379 0.0465
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0013 0.00000001373 0.00000001373
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0162 0.2769 0.9549
Echinococcus granulosus peroxisome assembly protein 26 0.0027 0.0256 0.0256
Trypanosoma cruzi alpha tubulin, putative 0.0027 0.0256 0.0882
Loa Loa (eye worm) animal heme peroxidase 0.0033 0.0377 0.0463
Loa Loa (eye worm) tubulin beta-4 chain 0.002 0.013 0.016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0101 0.0124
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Loa Loa (eye worm) norepinephrine transporter 0.0073 0.1112 0.1365
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0089 0.1427 0.1427
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Loa Loa (eye worm) hypothetical protein 0.007 0.1068 0.1311
Schistosoma mansoni DNA topoisomerase type I 0.0115 0.1906 0.1906
Echinococcus granulosus tyrosine protein kinase HCK 0.0089 0.1427 0.1427
Echinococcus multilocularis tubulin alpha chain 0.0027 0.0256 0.0256
Schistosoma mansoni hypothetical protein 0.0089 0.1427 0.1427
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0162 0.2769 1
Schistosoma mansoni nuclear hormone receptor 0.007 0.1068 0.1068
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0033 0.0379 0.0465
Brugia malayi DIX domain containing protein 0.0017 0.0086 0.0106
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.007 0.1068 0.1311
Leishmania major beta tubulin 0.002 0.013 0.0447
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.0039 0.0482 0.1662
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Brugia malayi Tubulin alpha-2 chain 0.0027 0.0256 0.0314
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Brugia malayi ephrin receptor 1 precursor 0.0089 0.1427 0.1751
Leishmania major GTP-binding protein, putative 0.002 0.0127 0.0437
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.1427 0.8918
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0089 0.1427 0.1427
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.007 0.1068 0.1311
Echinococcus granulosus tubulin subunit TubB 0.0027 0.0256 0.0256
Brugia malayi Protein kinase domain containing protein 0.0089 0.1427 0.1751
Leishmania major beta tubulin 0.002 0.013 0.0447
Brugia malayi hypothetical protein 0.0017 0.0086 0.0106
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0089 0.1427 0.8918
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Echinococcus granulosus retinoic acid receptor rxr beta a 0.007 0.1068 0.1068
Mycobacterium leprae putative cytochrome p450 0.0162 0.2769 1
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Schistosoma mansoni tubulin subunit beta 0.002 0.013 0.013
Schistosoma mansoni microtubule-associated protein tau 0.0551 1 1
Echinococcus multilocularis natriuretic peptide receptor 1 0.0089 0.1427 0.1427
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0089 0.1427 0.1427
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Trypanosoma brucei beta tubulin 0.002 0.013 0.0447
Loa Loa (eye worm) solute carrier family 6 member 4 0.0073 0.1112 0.1365
Trichomonas vaginalis tubulin alpha chain, putative 0.002 0.013 0.0593
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0035 0.0408 0.0501
Loa Loa (eye worm) TK/FER protein kinase 0.0089 0.1427 0.1751
Brugia malayi Cytochrome P450 family protein 0.0162 0.2769 0.34
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.1427 0.1751
Loa Loa (eye worm) hypothetical protein 0.0094 0.1509 0.1853
Schistosoma mansoni sodium/chloride dependent transporter 0.0073 0.1112 0.1112
Brugia malayi hypothetical protein 0.0017 0.0086 0.0106
Echinococcus multilocularis nuclear receptor nhr 48 0.0033 0.0379 0.0379
Loa Loa (eye worm) TK protein kinase 0.0089 0.1427 0.1751
Loa Loa (eye worm) alpha-tubulin 0.0027 0.0256 0.0314
Onchocerca volvulus 0.007 0.1068 0.1209
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0089 0.1427 0.8918
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Loa Loa (eye worm) hypothetical protein 0.0033 0.0379 0.0465
Trichomonas vaginalis tubulin beta chain, putative 0.002 0.013 0.0593
Brugia malayi Nuclear hormone receptor family member nhr-25 0.007 0.1068 0.1311
Echinococcus granulosus tubulin subunit beta 0.002 0.013 0.013
Trypanosoma brucei alpha tubulin 0.0027 0.0256 0.0882
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0019
Schistosoma mansoni protein kinase 0.0089 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0238 0.4185 0.5137
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0089 0.1427 0.1427
Plasmodium falciparum acyl-CoA synthetase 0.0014 0.0016 0.0058
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Brugia malayi Nuclear hormone receptor family member nhr-3 0.007 0.1068 0.1311
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0162 0.2769 0.9549
Loa Loa (eye worm) tubulin beta-2A chain 0.002 0.013 0.016
Loa Loa (eye worm) TK/INSR protein kinase 0.0089 0.1427 0.1751
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Schistosoma mansoni protein kinase 0.0089 0.1427 0.1427
Entamoeba histolytica protein kinase, putative 0.0089 0.1427 0.8918
Entamoeba histolytica serine/threonine kinase, putative 0.0089 0.1427 0.8918
Echinococcus granulosus tyrosine protein kinase Fyn 0.0089 0.1427 0.1427
Entamoeba histolytica tyrosine kinase, putative 0.0089 0.1427 0.8918
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0089 0.1427 0.1751
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.1427 1
Loa Loa (eye worm) hypothetical protein 0.0418 0.753 0.9244
Trichomonas vaginalis TKL family protein kinase 0.0089 0.1427 1
Schistosoma mansoni tyrosine kinase 0.0089 0.1427 0.1427
Echinococcus granulosus tubulin gamma 1 chain 0.002 0.013 0.013
Onchocerca volvulus 0.0033 0.0377 0.0426
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0018 0.0101 0.0296

Activities

Activity type Activity value Assay description Source Reference
Log RA (functional) = -2.26 Antimalarial activity of the compound was determined against chloroquine-resistant, mefloquine-sensitive Plasmodium falciparum W-2 clone ChEMBL. 11784134

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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