Detailed information for compound 1701783

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 512.585 | Formula: C25H31F3N2O4S
  • H donors: 0 H acceptors: 3 LogP: 4.27 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: Cc1ccc(cc1)S(=O)(=O)N1CCC(=O)N(CC1)[C@@H](C(C)C)COCc1cccc(c1)C(F)(F)F
  • InChi: 1S/C25H31F3N2O4S/c1-18(2)23(17-34-16-20-5-4-6-21(15-20)25(26,27)28)30-14-13-29(12-11-24(30)31)35(32,33)22-9-7-19(3)8-10-22/h4-10,15,18,23H,11-14,16-17H2,1-3H3/t23-/m1/s1
  • InChiKey: DGAFCYMUDSFNNL-HSZRJFAPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ataxin 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cathepsin L-like precursor 0.0022 0.0124 0.0325
Brugia malayi putative neuropeptide receptor NPR1 0.0027 0.0173 0.0471
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.02 0.0185
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.009 0.0223
Trichomonas vaginalis glutaminase, putative 0.0317 0.335 1
Trypanosoma cruzi cysteine peptidase, putative 0.0086 0.0819 0.2641
Schistosoma mansoni tar DNA-binding protein 0.0201 0.208 0.621
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0173 0.0517
Schistosoma mansoni cathepsin C 0.0012 0.0017 0.0051
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Onchocerca volvulus 0.0033 0.0239 0.0932
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0173 0.0516
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0173 0.0471
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0027 0.0173 0.0516
Schistosoma mansoni ap endonuclease 0.0023 0.0131 0.039
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0081 0.0764 1
Echinococcus multilocularis serotonin receptor 0.0027 0.0173 0.0157
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0081 0.0764 0.2464
Echinococcus granulosus 7tm_1 domain containing protein 0.0027 0.0173 0.0517
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0215 0.2111
Toxoplasma gondii cathepsin B 0.0098 0.0956 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Loa Loa (eye worm) cathepsin B 0.0098 0.0956 0.282
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0012 0.0017 0.0051
Loa Loa (eye worm) glutaminase 2 0.0317 0.335 1
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0197 0.0541
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0281 0.0793
Echinococcus multilocularis G protein coupled receptor 139 0.0027 0.0173 0.0157
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Loa Loa (eye worm) fibroinase 0.0029 0.0197 0.0545
Echinococcus multilocularis neuropeptide FF receptor 2 0.0027 0.0173 0.0157
Onchocerca volvulus Cathepsin L homolog 0.0012 0.0017 0.0005
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0012 0.0017 0.0051
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0062 0.0148
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0173 0.0516
Loa Loa (eye worm) hypothetical protein 0.0171 0.1756 0.522
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0173 0.0517
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0255 0.0713
Brugia malayi beta-NAC-like protein 0.0034 0.0255 0.0717
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0027 0.0173 0.0471
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0173 0.0517
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0281 0.3536
Echinococcus multilocularis 0.0016 0.0062 0.0046
Loa Loa (eye worm) hypothetical protein 0.0081 0.0764 0.2245
Plasmodium vivax vivapain-1 0.0019 0.009 0.0979
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0027 0.0173 0.0157
Brugia malayi follicle stimulating hormone receptor 0.0027 0.0173 0.0471
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.02 0.0598
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0173 0.0516
Brugia malayi Pre-SET motif family protein 0.0203 0.21 0.625
Schistosoma mansoni amine GPCR 0.0027 0.0173 0.0516
Entamoeba histolytica cysteine protease, putative 0.0029 0.0197 0.1696
Brugia malayi Cathepsin L-like precursor 0.0029 0.0197 0.0545
Brugia malayi Cytochrome P450 family protein 0.0027 0.0173 0.0471
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.0096
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0173 0.0517
Leishmania major cathepsin L-like protease 0.0029 0.0197 0.1331
Echinococcus multilocularis allatostatin A receptor 0.0027 0.0173 0.0157
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.009 0.0269
Schistosoma mansoni hypothetical protein 0.0027 0.0173 0.0516
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0131 0.1069
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0173 0.0157
Trichomonas vaginalis CAMK family protein kinase 0.011 0.108 0.3191
Giardia lamblia TCP-1 chaperonin subunit beta 0.0028 0.0186 0.1588
Echinococcus granulosus peptidase Clp S14 family 0.0053 0.046 0.1464
Plasmodium falciparum cysteine proteinase falcipain 1 0.0019 0.009 0.0979
Echinococcus multilocularis musashi 0.0033 0.0239 0.0223
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0186 0.0874
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0027 0.0173 0.0516
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0027 0.0173 0.0517
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.1043 0.3081
Trichomonas vaginalis CAMK family protein kinase 0.011 0.108 0.3191
Echinococcus multilocularis cysteine protease 0.0029 0.0197 0.0182
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0281 0.2153
Entamoeba histolytica cysteine proteinase 2 0.0019 0.009 0.0688
Brugia malayi TAR-binding protein 0.0201 0.208 0.6192
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Echinococcus granulosus orexin receptor type 2 0.0027 0.0173 0.0517
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0027 0.0173 0.0516
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0027 0.0173 0.0516
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Echinococcus multilocularis cathepsin b 0.029 0.3053 0.3042
Brugia malayi hypothetical protein 0.0027 0.0173 0.0471
Plasmodium vivax SET domain protein, putative 0.0029 0.02 0.2454
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0652 0.0638
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.0186 0.2263
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0173 0.0157
Schistosoma mansoni amine GPCR 0.0027 0.0173 0.0516
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0173 0.0157
Brugia malayi Cathepsin L-like precursor 0.0029 0.0197 0.0545
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0131 0.1522
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0004
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0027 0.0173 0.0516
Echinococcus granulosus alpha 1A adrenergic receptor 0.0027 0.0173 0.0517
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.009 0.0688
Schistosoma mansoni growth hormone secretagogue receptor 0.0027 0.0173 0.0516
Brugia malayi N-terminal motif family protein 0.0218 0.2267 0.6753
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0173 0.0516
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0652 0.6768
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0255 0.0783
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0032 0.0016
Onchocerca volvulus 0.0027 0.0173 0.0657
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0173 0.0517
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0016 0.0047
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0215 0.0653
Schistosoma mansoni coup transcription factor 0.0012 0.0016 0.0047
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0173 0.0517
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0054 0.0038
Echinococcus multilocularis orexin receptor type 2 0.0027 0.0173 0.0157
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0131 0.0378
Brugia malayi beta-lactamase family protein 0.0036 0.0281 0.0796
Brugia malayi cytochrome P450 0.0016 0.0062 0.0138
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0173 0.1091
Trichomonas vaginalis esterase, putative 0.0036 0.0281 0.0793
Onchocerca volvulus 0.0027 0.0173 0.0657
Onchocerca volvulus Cathepsin L homolog 0.0029 0.0197 0.076
Plasmodium falciparum T-complex protein 1 subunit beta 0.0028 0.0186 0.2261
Echinococcus granulosus cathepsin l cysteine peptidase 0.0029 0.0197 0.0598
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0027 0.0173 0.0157
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.009 0.0688
Onchocerca volvulus 0.0027 0.0173 0.0657
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0173 0.0471
Schistosoma mansoni tar DNA-binding protein 0.0201 0.208 0.621
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0173 0.0517
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0028 0.0186 0.0507
Brugia malayi hypothetical protein 0.0027 0.0173 0.0471
Onchocerca volvulus 0.0027 0.0173 0.0657
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0173 0.0157
Echinococcus granulosus neuropeptide receptor 0.0027 0.0173 0.0517
Echinococcus granulosus cathepsin l1 0.0022 0.0124 0.0357
Onchocerca volvulus 0.0027 0.0173 0.0657
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0012 0.0017 0.0051
Brugia malayi Serotonin receptor 0.0027 0.0173 0.0471
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0173 0.0517
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0012 0.0017 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0819 0.7433
Schistosoma mansoni amine GPCR 0.0027 0.0173 0.0516
Brugia malayi Papain family cysteine protease containing protein 0.0012 0.0017 0.0004
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0124 0.0322
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.02 0.1952
Onchocerca volvulus 0.0027 0.0173 0.0657
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Schistosoma mansoni hypothetical protein 0.0027 0.0173 0.0516
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.009 0.0688
Echinococcus granulosus g protein coupled receptor 0.0027 0.0173 0.0517
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0012 0.0017 0.0004
Schistosoma mansoni hypothetical protein 0.0014 0.0032 0.0094
Echinococcus multilocularis neuropeptide s receptor 0.0027 0.0173 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0255 0.0713
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0028 0.0186 0.2261
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0652 0.1796
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0173 0.0338
Loa Loa (eye worm) hypothetical protein 0.003 0.0215 0.0598
Brugia malayi glutaminase DH11.1 0.0317 0.335 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0004
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0029 0.0197 0.0545
Brugia malayi hypothetical protein 0.003 0.0215 0.0598
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0173 0.0471
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0173 0.0157
Onchocerca volvulus 0.0027 0.0173 0.0657
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0281 0.0793
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0081 0.0764 0.7957
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0027 0.0173 0.0471
Schistosoma mansoni hypothetical protein 0.0034 0.025 0.0745
Loa Loa (eye worm) ctsf protein 0.0029 0.0197 0.0545
Brugia malayi Cytochrome P450 family protein 0.0016 0.0062 0.0138
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.029 0.3053 0.9114
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Echinococcus multilocularis transcription factor btf3 0.0034 0.0255 0.0239
Echinococcus granulosus dro:myosuppressin receptor 0.0027 0.0173 0.0517
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0281 0.0793
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0201 0.208 0.6192
Echinococcus granulosus transcription factor btf3 0.0034 0.0255 0.0787
Echinococcus multilocularis G-protein coupled receptor, putative 0.0027 0.0173 0.0157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0027 0.0173 0.0471
Loa Loa (eye worm) hypothetical protein 0.0148 0.1501 0.4454
Trypanosoma cruzi cysteine peptidase, putative 0.0029 0.0197 0.0594
Brugia malayi sulfakinin receptor protein 0.0027 0.0173 0.0471
Brugia malayi beta-lactamase 0.0036 0.0281 0.0796
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0173 0.0516
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0027 0.0173 0.0471
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0173 0.0517
Echinococcus multilocularis peptidase Clp (S14 family) 0.0053 0.046 0.0445
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0281 0.0926
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0281 0.0926
Schistosoma mansoni peptidase Clp (S14 family) 0.0081 0.0764 0.2281
Onchocerca volvulus 0.0027 0.0173 0.0657
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Echinococcus multilocularis survival motor neuron protein 1 0.0265 0.2783 0.2772
Echinococcus multilocularis cathepsin L 0.0012 0.0017 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0819 0.7433
Loa Loa (eye worm) RNA binding protein 0.0201 0.208 0.6192
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0027 0.0173 0.0157
Brugia malayi larval opioid receptor 0.0027 0.0173 0.0471
Brugia malayi Cytochrome P450 family protein 0.0061 0.0546 0.159
Echinococcus multilocularis cathepsin L 0.0019 0.009 0.0074
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.029 0.3053 0.9114
Loa Loa (eye worm) TAR-binding protein 0.0201 0.208 0.6192
Echinococcus granulosus tar DNA binding protein 0.0201 0.208 0.6797
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0081 0.0764 0.5
Leishmania major cytochrome p450-like protein 0.0027 0.0173 0.1091
Echinococcus multilocularis neuropeptide receptor A26 0.0027 0.0173 0.0157
Schistosoma mansoni hypothetical protein 0.0034 0.025 0.0745
Onchocerca volvulus 0.0022 0.0124 0.0454
Echinococcus granulosus fmrfamide receptor 0.0027 0.0173 0.0517
Loa Loa (eye worm) TYRA-2 protein 0.0027 0.0173 0.0471
Echinococcus multilocularis GPCR, family 2 0.0034 0.025 0.0234
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0012 0.0017 0.0051
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0173 0.0517
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.1384 0.413
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0016 0.0047
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0131 0.0341
Echinococcus granulosus neuropeptide receptor A26 0.0027 0.0173 0.0517
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0255 0.3182
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0173 0.0157
Brugia malayi Cathepsin L-like precursor 0.0029 0.0197 0.0545
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0652 0.1948
Onchocerca volvulus 0.0029 0.0197 0.076
Entamoeba histolytica cysteine proteinase 1, putative 0.0019 0.009 0.0688
Brugia malayi hypothetical protein 0.0027 0.0173 0.0471
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0173 0.0157
Trypanosoma cruzi cysteine protease, putative 0.0019 0.009 0.0241
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0255 0.0717
Mycobacterium tuberculosis Conserved protein 0.0036 0.0281 0.0926
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0173 0.0516
Schistosoma mansoni opsin-like receptor 0.0027 0.0173 0.0516
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Leishmania major cathepsin L-like protease 0.0029 0.0197 0.1331
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0474 0.1374
Leishmania major hypothetical protein, conserved 0.0036 0.0281 0.2153
Echinococcus granulosus cathepsin l1 0.0029 0.0197 0.0598
Schistosoma mansoni cathepsin B (C01 family) 0.0012 0.0017 0.0051
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0218 0.2267 0.942
Echinococcus granulosus serine:threonine protein kinase PLK1 0.011 0.108 0.3505
Onchocerca volvulus 0.0033 0.0239 0.0932
Onchocerca volvulus 0.0036 0.0281 0.111
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0053 0.046 0.1682
Brugia malayi ORL1-like opioid receptor 0.0027 0.0173 0.0471
Echinococcus multilocularis lamin dm0 0.0033 0.0239 0.0223
Loa Loa (eye worm) hypothetical protein 0.0148 0.1501 0.4454
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.02 0.0185
Schistosoma mansoni ap endonuclease 0.0023 0.0131 0.039
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0173 0.0517
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Schistosoma mansoni cytochrome P450 0.0016 0.0062 0.0184
Brugia malayi RNA recognition motif domain containing protein 0.0201 0.208 0.6192
Echinococcus granulosus 7TM GPCR rhodopsin 0.0027 0.0173 0.0517
Loa Loa (eye worm) hypothetical protein 0.0036 0.0281 0.0796
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0652 0.1796
Echinococcus granulosus cytochrome P450 2K1 0.0016 0.0062 0.0152
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Brugia malayi AKH receptor 0.0027 0.0173 0.0471
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0173 0.0516
Echinococcus granulosus neuropeptide s receptor 0.0027 0.0173 0.0517
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.009 0.0241
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0028 0.0186 0.0556
Echinococcus multilocularis muscleblind protein 0.0171 0.1756 0.1743
Brugia malayi Tachykinin-like peptides receptor 99D 0.0027 0.0173 0.0471
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Trypanosoma cruzi polo-like protein kinase, putative 0.011 0.108 0.3503
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0137 0.1384 0.4103
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0281 0.087
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0131 0.0341
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0027 0.0173 0.0516
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0239 0.0668
Onchocerca volvulus 0.0029 0.02 0.0772
Brugia malayi hypothetical protein 0.0265 0.2783 0.83
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0054 0.0126
Onchocerca volvulus 0.0036 0.0281 0.111
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0173 0.0157
Brugia malayi cathepsin B-like cysteine proteinase 0.029 0.3053 0.911
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0081 0.0764 0.075
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Mycobacterium ulcerans lipase LipD 0.0036 0.0281 0.0667
Brugia malayi hypothetical protein 0.0027 0.0173 0.0471
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0186 0.2263
Echinococcus granulosus hypothetical protein 0.0027 0.0173 0.0517
Brugia malayi hypothetical protein 0.0027 0.0173 0.0471
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.02 0.0598
Loa Loa (eye worm) hypothetical protein 0.0022 0.0124 0.0325
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.011 0.108 0.3193
Giardia lamblia Kinase, PLK 0.011 0.108 1
Trypanosoma cruzi cruzipain precursor, putative 0.0086 0.0819 0.2641
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0255 0.0783
Echinococcus multilocularis serotonin receptor 0.0027 0.0173 0.0157
Brugia malayi Dopamine receptor protein 1 0.0027 0.0173 0.0471
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.025 0.0234
Brugia malayi T-complex protein 1, beta subunit 0.0028 0.0186 0.051
Brugia malayi RNA binding protein 0.0201 0.208 0.6192
Schistosoma mansoni hypothetical protein 0.0034 0.025 0.0745
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0027 0.0173 0.0471
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Loa Loa (eye worm) melatonin receptor type 1A 0.0027 0.0173 0.0471
Schistosoma mansoni biogenic amine receptor 0.0027 0.0173 0.0516
Schistosoma mansoni glutaminase 0.0317 0.335 1
Echinococcus granulosus neuropeptide receptor 0.0027 0.0173 0.0517
Brugia malayi neuropeptide F receptor 0.0027 0.0173 0.0471
Brugia malayi Dopamine receptor protein 2 0.0027 0.0173 0.0471
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.009 0.0269
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0281 0.3124
Brugia malayi hypothetical protein 0.0027 0.0173 0.0471
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0173 0.0517
Brugia malayi putative neuropeptide receptor 0.0027 0.0173 0.0471
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0029 0.0197 0.0182
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Schistosoma mansoni hypothetical protein 0.0034 0.025 0.0745
Trichomonas vaginalis CAMK family protein kinase 0.011 0.108 0.3191
Plasmodium vivax vivapain-2 0.0029 0.0197 0.2414
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0016 0.0047
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0173 0.0471
Leishmania major hypothetical protein, conserved 0.003 0.0215 0.1506
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.1043 0.3081
Echinococcus granulosus G protein coupled receptor 139 0.0027 0.0173 0.0517
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.0096
Echinococcus granulosus cathepsin L cysteine protease 0.0019 0.009 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Echinococcus multilocularis sex peptide receptor 0.0027 0.0173 0.0157
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0131 0.0345
Loa Loa (eye worm) hypothetical protein 0.0218 0.2267 0.6753
Loa Loa (eye worm) hypothetical protein 0.0106 0.1043 0.3081
Schistosoma mansoni adenoreceptor 0.0027 0.0173 0.0516
Loa Loa (eye worm) hypothetical protein 0.0022 0.0124 0.0325
Brugia malayi cathepsin Z-like cysteine proteinase 0.0012 0.0017 0.0004
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.025 0.077
Brugia malayi neuropeptide F receptor 0.0027 0.0173 0.0471
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0028 0.0186 0.1588
Onchocerca volvulus Serine\/threonine kinase homolog 0.011 0.108 0.4455
Brugia malayi intermediate filament protein 0.0033 0.0239 0.0668
Echinococcus granulosus cathepsin L cysteine proteinase 0.0029 0.0197 0.0598
Schistosoma mansoni transcription factor btf3 0.0034 0.0255 0.076
Trichomonas vaginalis CAMK family protein kinase 0.011 0.108 0.3191
Echinococcus granulosus cysteine protease 0.0019 0.009 0.0245
Schistosoma mansoni intermediate filament proteins 0.0033 0.0239 0.0712
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0281 0.0926
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0029 0.0197 0.0541
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0197 0.0541
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0029 0.0197 0.0541
Loa Loa (eye worm) MH2 domain-containing protein 0.0137 0.138 0.4091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.2431 1
Schistosoma mansoni lamin 0.0033 0.0239 0.0712
Trypanosoma cruzi cysteine proteinase, putative 0.0019 0.009 0.0241
Schistosoma mansoni neuropeptide receptor 0.0027 0.0173 0.0516
Mycobacterium tuberculosis Conserved protein 0.0036 0.0281 0.0926
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Loa Loa (eye worm) hypothetical protein 0.0171 0.1756 0.522
Trypanosoma brucei cysteine peptidase C (CPC) 0.0098 0.0956 0.8778
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.0475 0.1375
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0131 0.1069
Schistosoma mansoni cathepsin F (C01 family) 0.0029 0.0197 0.0589
Mycobacterium ulcerans hypothetical protein 0.0036 0.0281 0.0667
Echinococcus multilocularis muscleblind protein 1 0.0171 0.1756 0.1743
Echinococcus granulosus cathepsin b 0.029 0.3053 1
Loa Loa (eye worm) cytochrome P450 0.0016 0.0062 0.0138
Giardia lamblia Cathepsin B precursor 0.0098 0.0956 0.8829
Loa Loa (eye worm) cysteine protease 0.0029 0.0197 0.0545
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.011 0.108 0.1066
Loa Loa (eye worm) hypothetical protein 0.0029 0.02 0.0553
Brugia malayi Cytochrome P450 family protein 0.0027 0.0173 0.0471
Schistosoma mansoni alpha-1 adrenergic receptor 0.0027 0.0173 0.0516
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0819 0.7433
Echinococcus multilocularis cathepsin L cysteine protease 0.0029 0.0197 0.0182
Onchocerca volvulus Huntingtin homolog 0.0148 0.1501 0.6213
Onchocerca volvulus 0.0036 0.0281 0.111
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.025 0.0701
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0027 0.0173 0.0517
Echinococcus granulosus GPCR family 2 0.0034 0.025 0.077
Plasmodium vivax vivapain-3 0.0019 0.009 0.0979
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0029 0.0197 0.2414
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.0546 0.159
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0173 0.0157
Brugia malayi cathepsin L-like cysteine proteinase 0.0012 0.0017 0.0004
Onchocerca volvulus 0.0027 0.0173 0.0657
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0173 0.0157
Echinococcus granulosus cathepsin b 0.029 0.3053 1
Brugia malayi GnHR receptor homolog 0.0027 0.0173 0.0471
Entamoeba histolytica serine/threonine protein kinase, putative 0.011 0.108 1
Trichomonas vaginalis chaperonin, putative 0.0028 0.0186 0.0507
Echinococcus multilocularis cysteine protease 0.0029 0.0197 0.0182
Echinococcus granulosus lamin dm0 0.0033 0.0239 0.0733
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0173 0.0471
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0173 0.0157
Onchocerca volvulus 0.0029 0.0197 0.076
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0131 0.0676
Loa Loa (eye worm) hypothetical protein 0.0036 0.0281 0.0796
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0197 0.0541
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0028 0.0186 0.017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0004
Loa Loa (eye worm) transcription factor SMAD2 0.0137 0.138 0.4091
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0016 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.011 0.108 0.3225
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0239 0.0668
Brugia malayi Muscleblind-like protein 0.0171 0.1756 0.522
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0255 0.1894
Leishmania major cathepsin L-like protease 0.0086 0.0819 0.7433
Trichomonas vaginalis CAMK family protein kinase 0.011 0.108 0.3191
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0027 0.0173 0.0157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0819 0.7433
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0027 0.0173 0.0157
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0027 0.0173 0.0157
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Schistosoma mansoni cathepsin F (C01 family) 0.0029 0.0197 0.0589
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Trypanosoma cruzi major cysteine proteinase, putative 0.0069 0.0639 0.2047
Schistosoma mansoni tar DNA-binding protein 0.0201 0.208 0.621
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.1384 0.137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0819 0.7433
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0027 0.0173 0.0471
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0173 0.0514
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0173 0.0157
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.02 0.0598
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0173 0.0517
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0173 0.0516
Schistosoma mansoni opsin-like receptor 0.0027 0.0173 0.0516
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0012 0.0017 0.0051
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0131 0.0291
Brugia malayi Papain family cysteine protease containing protein 0.0012 0.0017 0.0004
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0081 0.0764 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0652 0.1796
Echinococcus granulosus allatostatin A receptor 0.0027 0.0173 0.0517
Brugia malayi hypothetical protein 0.002 0.0097 0.0244
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0173 0.0516
Loa Loa (eye worm) hypothetical protein 0.0036 0.0281 0.0796
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0029 0.0197 0.0182
Loa Loa (eye worm) hypothetical protein 0.0265 0.2783 0.83
Brugia malayi G protein-coupled receptor 0.0027 0.0173 0.0471
Schistosoma mansoni amine GPCR 0.0027 0.0173 0.0516
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0098 0.0956 0.2817
Brugia malayi beta-lactamase family protein 0.0036 0.0281 0.0796
Brugia malayi Cathepsin L-like cysteine proteinase 0.0022 0.0124 0.0325
Leishmania major cysteine peptidase A (CPA) 0.0029 0.0197 0.1331
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0819 0.7433
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0027 0.0173 0.0471
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0197 0.0541
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.0475 0.1375
Plasmodium vivax vivapain-2 0.0029 0.0197 0.2414
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0819 0.7433
Echinococcus granulosus intermediate filament protein 0.0033 0.0239 0.0733
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0186 0.1769
Schistosoma mansoni hypothetical protein 0.0027 0.0173 0.0516
Echinococcus granulosus geminin 0.0172 0.176 0.5742
Onchocerca volvulus Neuropeptide F receptor homolog 0.0027 0.0173 0.0657
Trypanosoma cruzi cysteine peptidase, putative 0.0086 0.0819 0.2641
Schistosoma mansoni neuropeptide receptor 0.0027 0.0173 0.0516
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0098 0.0956 0.8778
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0028 0.0186 0.0555
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0004
Echinococcus granulosus lamin 0.0033 0.0239 0.0733
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0197 0.0541
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0173 0.0157
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0173 0.0516
Onchocerca volvulus Huntingtin homolog 0.0148 0.1501 0.6213
Trichomonas vaginalis CAMK family protein kinase 0.011 0.108 0.3191
Onchocerca volvulus 0.0029 0.0197 0.076
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0281 0.0796
Loa Loa (eye worm) hypothetical protein 0.029 0.3053 0.911
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0819 0.7433
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0012 0.0017 0.0051
Brugia malayi Probable ClpP-like protease 0.0081 0.0764 0.2245
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0281 0.0839
Onchocerca volvulus 0.0231 0.2406 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.1384 0.413
Echinococcus multilocularis tar DNA binding protein 0.0201 0.208 0.2068
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0016 0.0047
Brugia malayi hypothetical protein 0.0027 0.0173 0.0471
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0012 0.0017 0.0004
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0173 0.0157
Brugia malayi Pre-SET motif family protein 0.0029 0.02 0.0553
Onchocerca volvulus 0.0027 0.0173 0.0657
Loa Loa (eye worm) hypothetical protein 0.0033 0.0239 0.0668
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0173 0.0516
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0028 0.0186 0.056
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0173 0.0516
Loa Loa (eye worm) hypothetical protein 0.0022 0.0124 0.0325
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0215 0.0653
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0173 0.0157
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0173 0.0517
Onchocerca volvulus 0.0027 0.0173 0.0657
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0281 0.0796
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Mycobacterium tuberculosis Conserved protein 0.0036 0.0281 0.0926
Loa Loa (eye worm) hypothetical protein 0.0036 0.0281 0.0796
Onchocerca volvulus 0.0027 0.0173 0.0657
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.02 0.0598
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0281 0.0266
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0281 0.0667
Brugia malayi Dopamine receptor 0.0027 0.0173 0.0471
Schistosoma mansoni hypothetical protein 0.0073 0.0676 0.2017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.1384 0.4504
Brugia malayi Cathepsin L-like precursor 0.0029 0.0197 0.0545
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.1384 0.137
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0016 0.0047
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0255 0.2236
Schistosoma mansoni opsin-like receptor 0.0027 0.0173 0.0516
Schistosoma mansoni hypothetical protein 0.0016 0.0062 0.0184
Toxoplasma gondii exonuclease III APE 0.0023 0.0131 0.1211
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.0676 0.198
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0016 0.0062 0.0148
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0081 0.0764 0.2136
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0255 0.2532
Echinococcus granulosus somatostatin receptor 0.0027 0.0173 0.0517
Toxoplasma gondii cytochrome p450 superfamily protein 0.0016 0.0062 0.0478
Leishmania major cathepsin L-like protease 0.0029 0.0197 0.1331
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0281 0.0874
Onchocerca volvulus 0.0029 0.0197 0.076
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0255 0.3182
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Loa Loa (eye worm) hypothetical protein 0.0029 0.0197 0.0545
Onchocerca volvulus 0.0012 0.0017 0.0005
Echinococcus multilocularis dro:myosuppressin receptor 0.0027 0.0173 0.0157
Brugia malayi hypothetical protein 0.0027 0.0173 0.0471
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.009 0.0278
Brugia malayi T-complex protein 1, beta subunit 0.0028 0.0186 0.051
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0016 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0173 0.0516
Echinococcus multilocularis g-protein coupled receptor 0.0027 0.0173 0.0157
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0012 0.0017 0.0051
Onchocerca volvulus 0.0029 0.0197 0.076
Trichomonas vaginalis set domain proteins, putative 0.0231 0.2406 0.7168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0012 0.0017 0.0004
Echinococcus granulosus serotonin receptor 0.0027 0.0173 0.0517
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0173 0.0157
Schistosoma mansoni neuropeptide receptor 0.0027 0.0173 0.0516
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0173 0.0157
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0081 0.0764 0.5
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0081 0.0764 1
Onchocerca volvulus 0.0054 0.0474 0.1917
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0027 0.0173 0.0157
Schistosoma mansoni survival motor neuron protein 0.0054 0.0474 0.1415
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.1384 0.4504
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.21 0.625
Plasmodium vivax unspecified product 0.0019 0.009 0.0979
Loa Loa (eye worm) hypothetical protein 0.0036 0.0281 0.0796
Schistosoma mansoni biogenic amine receptor 0.0027 0.0173 0.0516
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.029 0.3053 0.9114
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0281 0.0839
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0215 0.1506
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0012 0.0017 0.0051
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0027 0.0173 0.0516
Brugia malayi RE15519p 0.0027 0.0173 0.0471
Brugia malayi cathepsin L-like precursor 0.0022 0.0124 0.0325
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0173 0.0516
Echinococcus granulosus tachykinin peptides receptor 99D 0.0027 0.0173 0.0517
Onchocerca volvulus 0.0027 0.0173 0.0657
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0131 0.0375
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.0124 0.1008
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0079 0.0746 0.2401
Trypanosoma cruzi cysteine proteinase, putative 0.0019 0.009 0.0241
Echinococcus granulosus sex peptide receptor 0.0027 0.0173 0.0517
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0173 0.0516
Brugia malayi hypothetical protein 0.0148 0.1501 0.4454
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0652 0.5799
Brugia malayi Melatonin receptor type 1A 0.0027 0.0173 0.0471
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Schistosoma mansoni hypothetical protein 0.0172 0.176 0.5253
Brugia malayi cathepsin F-like cysteine proteinase 0.0012 0.0017 0.0004
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0016 0.0047
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0027 0.0173 0.0157
Echinococcus multilocularis cathepsin L cysteine protease 0.0029 0.0197 0.0182
Brugia malayi fibroinase precursor 0.0012 0.0017 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0819 0.7433
Echinococcus granulosus g protein coupled receptor 0.0027 0.0173 0.0517
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0173 0.0157
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Mycobacterium ulcerans beta-lactamase 0.0036 0.0281 0.0667
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0131 0.021
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0073 0.0172
Toxoplasma gondii t-complex protein beta subunit 0.0028 0.0186 0.1799
Brugia malayi Cathepsin L-like precursor 0.0029 0.0197 0.0545
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.02 0.0607
Brugia malayi Cathepsin L-like precursor 0.0029 0.0197 0.0545
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0281 0.0926
Onchocerca volvulus 0.0029 0.0197 0.076
Mycobacterium leprae Probable lipase LipE 0.0036 0.0281 0.3124
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0239 0.0668
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0281 0.0793
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.029 0.3053 1
Brugia malayi serine/threonine-protein kinase plk-2 0.011 0.108 0.3193
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0081 0.0764 0.7957
Echinococcus multilocularis somatostatin receptor 0.0027 0.0173 0.0157
Brugia malayi MH2 domain containing protein 0.0137 0.138 0.4091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.009 0.0219
Brugia malayi G-protein coupled receptor 0.0027 0.0173 0.0471
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0173 0.0471
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Loa Loa (eye worm) hypothetical protein 0.0032 0.0232 0.0649
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0173 0.0516
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0131 0.0375
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Echinococcus granulosus g protein coupled receptor 0.0027 0.0173 0.0517
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0081 0.0764 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0173 0.0157
Schistosoma mansoni neuropeptide receptor 0.0027 0.0173 0.0516
Schistosoma mansoni cathepsin S (C01 family) 0.0012 0.0017 0.0051
Onchocerca volvulus 0.0029 0.0197 0.076
Schistosoma mansoni neuropeptide f receptor 76f 0.0027 0.0173 0.0516
Onchocerca volvulus 0.0027 0.0173 0.0657
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.0124 0.0371
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0652 0.2493
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Giardia lamblia Cathepsin B precursor 0.0098 0.0956 0.8829
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0173 0.0516
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.009 0.0278
Trypanosoma brucei polo-like protein kinase 0.011 0.108 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0053 0.046 0.1682
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0081 0.0764 1
Brugia malayi Serotonin receptor 0.0027 0.0173 0.0471
Schistosoma mansoni tar DNA-binding protein 0.0201 0.208 0.621
Brugia malayi Papain family cysteine protease containing protein 0.0012 0.0017 0.0004
Leishmania major T-complex protein 1, beta subunit, putative 0.0028 0.0186 0.1218
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0173 0.0517
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0062 0.0148
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Brugia malayi cathepsin L precursor 0.0012 0.0017 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.009 0.0688
Onchocerca volvulus 0.0027 0.0173 0.0657
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0016 0.0047
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.025 0.077
Echinococcus granulosus g-protein coupled receptor 0.0027 0.0173 0.0517
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0131 0.0345
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0073 0.0172
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0652 0.1948
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0131 0.0115
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0197 0.0541
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0173 0.0517
Onchocerca volvulus Cathepsin L homolog 0.0029 0.0197 0.076
Schistosoma mansoni kinase 0.0056 0.0491 0.1466
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0819 0.7433
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0173 0.0157
Brugia malayi hypothetical protein 0.0027 0.0173 0.0471
Echinococcus granulosus muscleblind protein 0.0171 0.1756 0.573
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0027 0.0173 0.0517
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0197 0.1696
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0281 0.087
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0281 0.0926
Onchocerca volvulus Cathepsin F homolog 0.0029 0.0197 0.076
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0215 0.2654
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0016 0.0047
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0215 0.2654
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.009 0.0219
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0281 0.0926
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0131 0.0676
Entamoeba histolytica hypothetical protein 0.0034 0.0255 0.2236
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0173 0.0514
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0215 0.2654
Leishmania major cathepsin L-like protease 0.0029 0.0197 0.1331
Echinococcus multilocularis geminin 0.0172 0.176 0.1747
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0173 0.0157
Brugia malayi cathepsin Z-like cysteine proteinase 0.0012 0.0017 0.0004
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0027 0.0173 0.0657
Schistosoma mansoni myosin xvIII 0.0027 0.0173 0.0516
Brugia malayi hypothetical protein 0.0027 0.0173 0.0471
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0028 0.0186 0.1218
Loa Loa (eye worm) hypothetical protein 0.0034 0.025 0.0701
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0019 0.009 0.0241
Schistosoma mansoni amine GPCR 0.0027 0.0173 0.0516
Onchocerca volvulus 0.0027 0.0173 0.0657
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0281 0.0793
Brugia malayi Papain family cysteine protease containing protein 0.0029 0.0197 0.0545
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.1043 0.3081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0124 0.0322
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Schistosoma mansoni hypothetical protein 0.0172 0.176 0.5253
Schistosoma mansoni hypothetical protein 0.0027 0.0173 0.0516
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0098 0.0956 0.3093
Echinococcus granulosus neuropeptide FF receptor 2 0.0027 0.0173 0.0517
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Loa Loa (eye worm) beta-lactamase 0.0036 0.0281 0.0796
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0173 0.0157
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0281 0.0926
Schistosoma mansoni hypothetical protein 0.0054 0.0474 0.1415
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0173 0.0157
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0173 0.0517
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0016 0.0047
Plasmodium falciparum cysteine proteinase falcipain 3 0.0029 0.0197 0.2414
Mycobacterium ulcerans glutaminase 0.0317 0.335 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0054 0.0115
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0281 0.0667
Entamoeba histolytica cysteine protease, putative 0.0019 0.009 0.0688
Echinococcus granulosus cathepsin L 0.0012 0.0017 0.0004
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0027 0.0173 0.0471
Brugia malayi G-protein coupled receptor 0.0027 0.0173 0.0471
Leishmania major cathepsin L-like protease 0.0086 0.0819 0.7433
Echinococcus granulosus survival motor neuron protein 1 0.0265 0.2783 0.9111
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0032 0.0052
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0027 0.0173 0.0516
Schistosoma mansoni histamine h1 receptor 0.0027 0.0173 0.0516
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0053 0.046 0.5674
Schistosoma mansoni lamin 0.0033 0.0239 0.0712
Schistosoma mansoni tar DNA-binding protein 0.0201 0.208 0.621
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.1384 0.413
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0131 0.1522
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Echinococcus granulosus peptide allatostatin:somatostatin 0.0027 0.0173 0.0517
Toxoplasma gondii cathepsin CPL 0.0029 0.0197 0.1921
Loa Loa (eye worm) hypothetical protein 0.0036 0.0281 0.0796
Leishmania major cathepsin L-like protease 0.0029 0.0197 0.1331
Brugia malayi Cathepsin L-like precursor 0.0022 0.0124 0.0325
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0652 0.2096
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0197 0.0541
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0189 0.0569
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0173 0.0516
Toxoplasma gondii ABC1 family protein 0.0036 0.0281 0.2814
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0029 0.0197 0.0545
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0027 0.0173 0.0471
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.025 0.0701
Giardia lamblia Cathepsin B precursor 0.0098 0.0956 0.8829
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0173 0.0157
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0004
Loa Loa (eye worm) glutaminase 0.0317 0.335 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.009 0.0269
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.025 0.0234
Brugia malayi G protein-coupled receptor F59B2.13 0.0027 0.0173 0.0471
Brugia malayi Latrophilin receptor protein 2 0.0034 0.025 0.0701
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0016 0.0047
Loa Loa (eye worm) hypothetical protein 0.0073 0.0676 0.198
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0197 0.0541
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0012 0.0017 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.0819 0.7433
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0081 0.0764 0.2136
Schistosoma mansoni biogenic amine receptor 0.0027 0.0173 0.0516
Echinococcus multilocularis cathepsin b 0.029 0.3053 0.3042
Loa Loa (eye worm) T-complex protein 1 0.0028 0.0186 0.051
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0173 0.0517
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0173 0.0471
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0173 0.0517
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0197 0.0541
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0098 0.0956 0.2854
Trypanosoma cruzi polo-like protein kinase, putative 0.011 0.108 0.3503
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Trypanosoma cruzi cysteine peptidase, putative 0.0086 0.0819 0.2641
Leishmania major cathepsin L-like protease 0.0086 0.0819 0.7433
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0137 0.1384 0.4103
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0197 0.1696
Echinococcus multilocularis lamin 0.0033 0.0239 0.0223
Onchocerca volvulus 0.0027 0.0173 0.0657
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.029 0.3053 0.9114
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0028 0.0186 0.0555
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0029 0.0197 0.2414
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0028 0.0186 0.0555
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.011 0.108 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Leishmania major basic transcription factor 3a, putative 0.0034 0.0255 0.1894
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0027 0.0173 0.0471
Trichomonas vaginalis CAMK family protein kinase 0.011 0.108 0.3191
Toxoplasma gondii hypothetical protein 0.0028 0.0186 0.1801
Echinococcus granulosus cathepsin L 0.0019 0.009 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0197 0.0541
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.009 0.0223
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0173 0.0157
Loa Loa (eye worm) hypothetical protein 0.0027 0.0173 0.0471
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0255 0.0713

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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