Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | flap endonuclease 1, putative | 0.0027 | 0.3013 | 0.5 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0027 | 0.3013 | 0.5 |
Brugia malayi | Flap endonuclease-1 | 0.0027 | 0.3013 | 0.3013 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.5371 | 0.5371 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.5371 | 0.906 |
Brugia malayi | hypothetical protein | 0.0037 | 0.5929 | 0.5929 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 1 | 1 |
Schistosoma mansoni | flap endonuclease-1 | 0.0024 | 0.2279 | 0.3844 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.5929 | 1 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0027 | 0.3013 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.5929 | 1 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0027 | 0.3013 | 0.5 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0027 | 0.3013 | 0.5 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0027 | 0.3013 | 0.3013 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.5929 | 1 |
Echinococcus granulosus | flap endonuclease 1 | 0.0027 | 0.3013 | 0.5082 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0027 | 0.3013 | 0.5 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0027 | 0.3013 | 0.5082 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.5929 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.5929 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.5929 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.5371 | 0.5371 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.5929 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.5929 | 1 |
Plasmodium falciparum | flap endonuclease 1 | 0.0027 | 0.3013 | 0.5 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0027 | 0.3013 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.