TDR Targets

Basic information

Technical information

TDR Targets ID: 1703548
Name: 3-(4-ethoxyphenyl)-1-[[1-[(4-fluorophenyl)met hyl]piperidin-4-yl]methyl]urea
MW: 385.475 | Formula: C22H28FN3O2
H donors: 2 H acceptors: 1 LogP: 3.64 Rotable bonds: 9
Rule of 5 violations (Lipinski): 1
SMILES: CCOc1ccc(cc1)NC(=O)NCC1CCN(CC1)Cc1ccc(cc1)F
InChi: 1S/C22H28FN3O2/c1-2-28-21-9-7-20(8-10-21)25-22(27)24-15-17-11-13-26(14-12-17)16-18-3-5-19(23)6-4-18/h3-10,17H,2,11-16H2,1H3,(H2,24,25,27)
InChiKey: PVFDZNDRQHHWTE-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

3-(4-ethoxyphenyl)-1-[[1-[(4-fluorophenyl)methyl]-4-piperidyl]methyl]urea
3-(4-ethoxyphenyl)-1-[[1-[(4-fluorophenyl)methyl]-4-piperidinyl]methyl]urea
3-(4-ethoxyphenyl)-1-[[1-(4-fluorobenzyl)-4-piperidyl]methyl]urea

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	glycoprotein hormones, alpha polypeptide	Starlite/ChEMBL	No references
Homo sapiens	GNAS complex locus	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma japonicum	ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	Get druggable targets OG5_131088	All targets in OG5_131088

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Toxoplasma gondii	intraflagellar transport protein 172, putative	glycoprotein hormones, alpha polypeptide	116 aa	94 aa	26.6 %
Schistosoma mansoni	GTP-binding protein alpha subunit gna	GNAS complex locus	394 aa	450 aa	28.7 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0051	0.0127	0.3289
Plasmodium vivax	flap endonuclease 1, putative	0.0027	0.0044	0.133
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0021	0.0026	0.0373
Trypanosoma cruzi	flap endonuclease-1 (FEN-1), putative	0.0027	0.0044	0.1653
Toxoplasma gondii	ImpB/MucB/SamB family protein	0.0032	0.0063	0.2711
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0021	0.0026	0.0373
Trichomonas vaginalis	glutathione reductase, putative	0.0021	0.0026	0.0005
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0021	0.1281
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Trichomonas vaginalis	flap endonuclease-1, putative	0.0027	0.0044	0.0023
Schistosoma mansoni	DNA polymerase eta	0.0046	0.0109	0.4008
Echinococcus multilocularis	transcription factor eb	0.0111	0.0328	1
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0051	0.0127	0.332
Entamoeba histolytica	modulator of drug activity B homolog, putative	0.034	0.1094	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0055	0.0139	0.4098
Treponema pallidum	NADH oxidase	0.0021	0.0026	0.5
Schistosoma mansoni	flap endonuclease-1	0.0024	0.0035	0.1074
Brugia malayi	Flap endonuclease-1	0.0027	0.0044	0.1033
Leishmania major	DNA polymerase eta, putative	0.0046	0.0109	0.6247
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0021	0.0026	0.0373
Trichomonas vaginalis	conserved hypothetical protein	0.034	0.1094	0.1075
Trichomonas vaginalis	conserved hypothetical protein	0.034	0.1094	0.1075
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Schistosoma mansoni	eyes absent homolog	0.0091	0.0259	1
Plasmodium vivax	thioredoxin reductase, putative	0.0062	0.0162	1
Trichomonas vaginalis	conserved hypothetical protein	0.034	0.1094	0.1075
Giardia lamblia	NADPH oxidoreductase, putative	0.0819	0.2702	1
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Trypanosoma brucei	dihydrolipoyl dehydrogenase	0.0021	0.0026	0.1606
Trichomonas vaginalis	conserved hypothetical protein	0.034	0.1094	0.1075
Leishmania major	acetoin dehydrogenase e3 component-like protein	0.0021	0.0026	0.0373
Mycobacterium ulcerans	dihydrolipoamide dehydrogenase	0.0021	0.0026	1
Trichomonas vaginalis	conserved hypothetical protein	0.034	0.1094	0.1075
Plasmodium falciparum	thioredoxin reductase	0.0062	0.0162	1
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0051	0.0127	0.332
Echinococcus granulosus	dna polymerase eta	0.0046	0.0109	0.3146
Trichomonas vaginalis	conserved hypothetical protein	0.034	0.1094	0.1075
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0109	0.2799
Trypanosoma cruzi	trypanothione reductase, putative	0.0021	0.0026	0.0373
Leishmania major	2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein	0.0021	0.0026	0.0373
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0055	0.0139	0.4098
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0021	0.1281
Giardia lamblia	NADPH oxidoreductase, putative	0.0819	0.2702	1
Leishmania major	DNA polymerase eta, putative	0.0032	0.0063	0.2983
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0055	0.0139	0.3645
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Mycobacterium tuberculosis	Probable oxidoreductase	0.0021	0.0026	0.0373
Entamoeba histolytica	Flap nuclease, putative	0.0027	0.0044	0.0218
Brugia malayi	hypothetical protein	0.0091	0.0259	0.6996
Giardia lamblia	NADPH oxidoreductase, putative	0.0819	0.2702	1
Brugia malayi	ImpB/MucB/SamB family protein	0.002	0.0021	0.0385
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Loa Loa (eye worm)	hypothetical protein	0.0111	0.0326	0.8845
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0021	0.1281
Leishmania major	dihydrolipoamide dehydrogenase, putative	0.0021	0.0026	0.0373
Loa Loa (eye worm)	helix-loop-helix DNA-binding domain-containing protein	0.0111	0.0326	0.8845
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.002	0.0021	0.0487
Brugia malayi	glutathione reductase	0.0062	0.0162	0.4303
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0021	0.1281
Brugia malayi	MH2 domain containing protein	0.0123	0.0367	1
Echinococcus multilocularis	flap endonuclease 1	0.0027	0.0044	0.1114
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.0139	0.522
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Echinococcus multilocularis	dihydrolipoamide dehydrogenase	0.0021	0.0026	0.0547
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.002	0.0021	0.0383
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0021	0.0026	0.5
Trypanosoma brucei	DNA polymerase IV, putative	0.002	0.0021	0.1281
Chlamydia trachomatis	dihydrolipoyl dehydrogenase	0.0021	0.0026	0.5
Echinococcus granulosus	dihydrolipoamide dehydrogenase	0.0021	0.0026	0.0547
Giardia lamblia	Flap structure-specific endonuclease	0.0027	0.0044	0.0087
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.002	0.0021	0.034
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0259	0.6982
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Loa Loa (eye worm)	thioredoxin reductase	0.0062	0.0162	0.4276
Trichomonas vaginalis	conserved hypothetical protein	0.034	0.1094	0.1075
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0021	0.1281
Trypanosoma brucei	dihydrolipoamide dehydrogenase, point mutation	0.0021	0.0026	0.1606
Trichomonas vaginalis	conserved hypothetical protein	0.0479	0.1562	0.1544
Brugia malayi	latrophilin 2 splice variant baaae	0.0035	0.0072	0.1805
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.0139	0.522
Mycobacterium tuberculosis	Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot	0.0021	0.0026	0.0373
Echinococcus granulosus	thioredoxin glutathione reductase	0.0062	0.0162	0.4807
Loa Loa (eye worm)	transcription factor SMAD2	0.0123	0.0367	1
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0021	0.0026	0.0373
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Trypanosoma brucei	dihydrolipoamide dehydrogenase	0.0021	0.0026	0.1606
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Echinococcus multilocularis	dna polymerase eta	0.0046	0.0109	0.3146
Brugia malayi	dihydrolipoyl dehydrogenase, mitochondrial precursor, putative	0.0021	0.0026	0.0531
Wolbachia endosymbiont of Brugia malayi	dihydrolipoamide dehydrogenase E3 component	0.0021	0.0026	0.5
Mycobacterium ulcerans	flavoprotein disulfide reductase	0.0021	0.0026	1
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0021	0.0026	0.0373
Plasmodium falciparum	flap endonuclease 1	0.0027	0.0044	0.133
Brugia malayi	Latrophilin receptor protein 2	0.0016	0.0009	0.0046
Giardia lamblia	NADH oxidase lateral transfer candidate	0.0021	0.0026	0.002
Brugia malayi	Thioredoxin reductase	0.0062	0.0162	0.4303
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Loa Loa (eye worm)	flap endonuclease-1	0.0027	0.0044	0.0991
Echinococcus granulosus	transcription factor eb	0.0111	0.0328	1
Trichomonas vaginalis	FMN-dependent NADH-azoreductase, putative	0.034	0.1094	0.1075
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0072	0.1767
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0021	0.1281
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.002	0.0021	0.0383
Trichomonas vaginalis	NAD(P)H dehydrogenase, putative	0.0819	0.2702	0.2687
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Leishmania major	dihydrolipoamide dehydrogenase, putative	0.0021	0.0026	0.0373
Trypanosoma brucei	dihydrolipoamide dehydrogenase	0.0021	0.0026	0.1606
Brugia malayi	ImpB/MucB/SamB family protein	0.0046	0.0109	0.2832
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Trichomonas vaginalis	conserved hypothetical protein	0.034	0.1094	0.1075
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0021	0.0026	0.0373
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Brugia malayi	Helix-loop-helix DNA-binding domain containing protein	0.0111	0.0328	0.89
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0016	0.0009	0.0046
Loa Loa (eye worm)	glutathione reductase	0.0062	0.0162	0.4276
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Echinococcus granulosus	flap endonuclease 1	0.0027	0.0044	0.1114
Trypanosoma cruzi	trypanothione reductase, putative	0.0062	0.0162	1
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.0062	0.0162	1
Trichomonas vaginalis	NAD(P)H dehydrogenase, putative	0.2994	1	1
Toxoplasma gondii	flap structure-specific endonuclease 1, putative	0.0027	0.0044	0.133
Entamoeba histolytica	hypothetical protein	0.034	0.1094	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.0139	0.522
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Plasmodium vivax	glutathione reductase, putative	0.0062	0.0162	1
Trypanosoma brucei	DNA polymerase IV, putative	0.002	0.0021	0.1281
Trypanosoma brucei	flap endonuclease-1 (FEN-1), putative	0.0027	0.0044	0.2722
Trichomonas vaginalis	mercuric reductase, putative	0.0021	0.0026	0.0005
Trypanosoma brucei	DNA polymerase eta, putative	0.0046	0.0109	0.6727
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0021	0.1281
Trypanosoma cruzi	dihydrolipoyl dehydrogenase, putative	0.0021	0.0026	0.0373
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0021	0.1281
Plasmodium falciparum	glutathione reductase	0.0062	0.0162	1
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Trichomonas vaginalis	conserved hypothetical protein	0.034	0.1094	0.1075
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0021	0.0026	0.0373
Trypanosoma brucei	DNA polymerase IV, putative	0.002	0.0021	0.1281
Leishmania major	trypanothione reductase	0.0062	0.0162	1
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0062	0.0162	0.4807
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Loa Loa (eye worm)	hypothetical protein	0.0051	0.0127	0.3289
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0055	0.0139	0.4098
Echinococcus granulosus	dna polymerase kappa	0.002	0.0021	0.0383
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Trypanosoma cruzi	DNA polymerase eta, putative	0.0032	0.0063	0.2983
Trypanosoma cruzi	dihydrolipoyl dehydrogenase, putative	0.0021	0.0026	0.0373
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Trichomonas vaginalis	NAD(P)H dehydrogenase, putative	0.0819	0.2702	0.2687
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0259	0.6982
Echinococcus multilocularis	dna polymerase kappa	0.002	0.0021	0.0383
Schistosoma mansoni	hypothetical protein	0.0035	0.0072	0.253
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0055	0.0139	0.3674
Trypanosoma brucei	trypanothione reductase	0.0062	0.0162	1
Schistosoma mansoni	dihydrolipoamide dehydrogenase	0.0021	0.0026	0.0697
Mycobacterium ulcerans	dihydrolipoamide dehydrogenase, LpdB	0.0021	0.0026	1
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Leishmania major	flap endonuclease-1 (FEN-1), putative	0.0027	0.0044	0.1653
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Trypanosoma cruzi	DNA polymerase eta, putative	0.0046	0.0109	0.6247
Schistosoma mansoni	terminal deoxycytidyl transferase	0.002	0.0021	0.0487
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Loa Loa (eye worm)	MH2 domain-containing protein	0.0123	0.0367	1
Trichomonas vaginalis	NAD(P)H dehydrogenase, putative	0.0819	0.2702	0.2687
Toxoplasma gondii	thioredoxin reductase	0.0062	0.0162	1
Trichomonas vaginalis	modulator of drug activity B, putative	0.034	0.1094	0.1075
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0021	0.1281
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0055	0.0139	0.4098
Trypanosoma brucei	unspecified product	0.002	0.0021	0.1281
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0021	0.1281
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0021	0.0026	0.0373
Trichomonas vaginalis	conserved hypothetical protein	0.0819	0.2702	0.2687
Wolbachia endosymbiont of Brugia malayi	dihydrolipoamide dehydrogenase E3 component	0.0021	0.0026	0.5
Entamoeba histolytica	iron-sulfur flavoprotein, putative	0.034	0.1094	1

Activities

Activity type	Activity value	Assay description	Source	Reference
Potency (functional)	1.7783 uM	PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	12.5893 uM	PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory)	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2137828

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1703548