Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0016 | 0.0033 |
Plasmodium falciparum | plasmepsin I | 0.0055 | 0.0033 | 0.5369 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 0.0095 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0021 | 0.0019 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0035 | 0.0013 | 0.0008 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0009 | 0.0011 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0083 | 0.0061 | 0.0185 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0047 | 0.0137 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0041 | 0.0019 | 0.0016 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 0.0095 | 1 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0083 | 0.0061 | 1 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0028 | 0.0005 | 0.0045 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Schistosoma mansoni | endoplasmin | 0.0035 | 0.0013 | 0.0008 |
Schistosoma mansoni | alpha-glucosidase | 0.0159 | 0.014 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0027 | 0.0026 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0043 | 0.0021 | 0.0191 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0047 | 0.005 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0083 | 0.0061 | 0.0519 |
Schistosoma mansoni | amine oxidase | 0.0083 | 0.0061 | 0.0068 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0041 | 0.0018 | 0.0043 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0013 | 0.0024 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0018 | 0.1563 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0041 | 0.0019 | 0.0013 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0163 | 0.0143 | 0.0168 |
Trypanosoma brucei | heat shock protein, putative | 0.0035 | 0.0013 | 0.1354 |
Schistosoma mansoni | serine/threonine protein kinase | 0.8015 | 0.8211 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0337 | 0.0323 | 0.0386 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0041 | 0.0018 | 0.1563 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0006 | 0.0949 |
Schistosoma mansoni | alpha glucosidase | 0.0041 | 0.0018 | 0.0015 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0035 | 0.0013 | 0.0832 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0043 | 0.0021 | 0.0177 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0012 | 0.0006 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0043 | 0.0021 | 0.0052 |
Plasmodium vivax | heat shock protein 86, putative | 0.0035 | 0.0013 | 0.2083 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0041 | 0.0019 | 0.0016 |
Echinococcus granulosus | expressed protein | 0.0367 | 0.0354 | 0.1148 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0055 | 0.0033 | 0.0091 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0041 | 0.0018 | 0.0015 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 0.0095 | 1 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0028 | 0.0005 | 0.0569 |
Treponema pallidum | heat shock protein 90 | 0.0028 | 0.0005 | 1 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0083 | 0.0061 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0016 | 0.1278 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0009 | 0.0011 |
Plasmodium falciparum | plasmepsin II | 0.0055 | 0.0033 | 0.5369 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0006 | 0.0949 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0013 | 0.0007 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0013 | 0.1347 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0163 | 0.0143 | 0.0168 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0009 | 0.0003 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0021 | 0.0191 |
Schistosoma mansoni | alpha-glucosidase | 0.0159 | 0.014 | 0.0163 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0019 | 0.161 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0043 | 0.0021 | 0.0052 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0055 | 0.0033 | 0.0033 |
Trypanosoma brucei | heat shock protein, putative | 0.0035 | 0.0013 | 0.1354 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0455 | 0.0444 | 0.1445 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0061 | 0.0068 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0041 | 0.0018 | 0.0043 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0033 | 0.0033 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0018 | 0.1462 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0083 | 0.0061 | 0.0068 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0019 | 0.0043 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0083 | 0.0061 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0043 | 0.0021 | 0.0177 |
Trypanosoma brucei | heat shock protein, putative | 0.0035 | 0.0013 | 0.1354 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0083 | 0.0061 | 0.0185 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0115 | 0.0095 | 0.0108 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0043 | 0.0021 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0009 | 0.0003 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0033 | 0.0091 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 0.0095 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0068 | 0.0046 | 0.4655 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0041 | 0.0018 | 0.2996 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.0021 | 0.1851 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0041 | 0.0019 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0009 | 0.0003 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0035 | 0.0013 | 0.0832 |
Schistosoma mansoni | heat shock protein | 0.0035 | 0.0013 | 0.0008 |
Trypanosoma brucei | heat shock protein, putative | 0.0035 | 0.0013 | 0.1354 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0185 | 0.0166 | 0.0195 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0083 | 0.0061 | 0.0559 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0055 | 0.0033 | 0.0027 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0083 | 0.0061 | 0.0559 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 0.0095 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0021 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.2982 | 0.304 | 0.3698 |
Trypanosoma brucei | glucosidase, putative | 0.0041 | 0.0018 | 0.1948 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 0.0095 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0455 | 0.0444 | 0.1445 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0035 | 0.0013 | 0.0832 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0083 | 0.0061 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0006 | 0.0949 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0041 | 0.0019 | 0.0044 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0083 | 0.0061 | 0.0056 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0094 | 0.0073 | 0.0223 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0035 | 0.0013 | 0.1354 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0012 | 0.0008 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0278 | 0.0262 | 0.2379 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0009 | 0.0003 |
Onchocerca volvulus | Diphthamide biosynthesis protein 7 homolog | 0.2982 | 0.304 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0041 | 0.0018 | 0.1948 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0033 | 0.0033 |
Brugia malayi | beta-lactamase family protein | 0.0043 | 0.0021 | 0.0015 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0068 | 0.0046 | 0.4655 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0009 | 0.0011 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0055 | 0.0033 | 0.0091 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0006 | 0.0051 |
Plasmodium falciparum | heat shock protein 90 | 0.0035 | 0.0013 | 0.2083 |
Echinococcus multilocularis | expressed protein | 0.0367 | 0.0354 | 0.1148 |
Mycobacterium ulcerans | monoamine oxidase | 0.0083 | 0.0061 | 0.0519 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0006 | 0.0949 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0061 | 0.0068 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0083 | 0.0061 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0035 | 0.0013 | 0.1354 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0006 | 0.0001 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.0012 | 0.0008 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0078 | 0.0088 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0047 | 0.0137 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0009 | 0.0003 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0035 | 0.0013 | 0.0832 |
Brugia malayi | SWIRM domain containing protein | 0.0083 | 0.0061 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0061 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0061 | 0.0068 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0035 | 0.0013 | 0.1354 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0035 | 0.0013 | 0.1354 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0082 | 0.006 | 0.0181 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0043 | 0.0021 | 0.0191 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0047 | 0.4709 |
Onchocerca volvulus | 0.0083 | 0.0061 | 0.0183 | |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0017 | 0.004 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0009 | 0.0003 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0043 | 0.0021 | 0.2223 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0035 | 0.0013 | 0.1354 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.1177 | 0.1185 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0061 | 0.0068 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0021 | 0.1754 |
Trypanosoma brucei | heat shock protein, putative | 0.0035 | 0.0013 | 0.1354 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0083 | 0.0061 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0043 | 0.0021 | 0.3419 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0043 | 0.0021 | 0.0019 |
Schistosoma mansoni | heat shock protein | 0.0035 | 0.0013 | 0.0008 |
Echinococcus multilocularis | Cyclin dependent kinase 2 associated protein | 0.2982 | 0.304 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0043 | 0.0021 | 0.0191 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0083 | 0.0061 | 0.6291 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0041 | 0.0018 | 0.1563 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0009 | 0.0011 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0115 | 0.0095 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.006 | 0.0067 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0017 | 0.004 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0115 | 0.0095 | 0.0089 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0006 | 0.0001 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0083 | 0.0061 | 1 |
Onchocerca volvulus | 0.0043 | 0.0021 | 0.005 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0018 | 0.1462 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0055 | 0.0033 | 0.5369 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0061 | 0.0068 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0028 | 0.0005 | 0.0875 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0013 | 0.1347 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0021 | 0.0019 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0013 | 0.0024 |
Mycobacterium leprae | Probable lipase LipE | 0.0043 | 0.0021 | 0.3419 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0019 | 0.161 |
Mycobacterium ulcerans | dehydrogenase | 0.0083 | 0.0061 | 0.0519 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0185 | 0.0166 | 0.016 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0016 | 0.001 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0082 | 0.006 | 0.0055 |
Echinococcus multilocularis | geminin | 0.0337 | 0.0323 | 0.1046 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0083 | 0.0061 | 0.0185 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0013 | 0.0008 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0043 | 0.0021 | 0.1851 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.0021 | 0.1851 |
Brugia malayi | Heterochromatin protein 1 | 0.0069 | 0.0047 | 0.0041 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0009 | 0.0011 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0012 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0007 | 0.0002 |
Loa Loa (eye worm) | endoplasmin | 0.0035 | 0.0013 | 0.0008 |
Onchocerca volvulus | 0.0043 | 0.0021 | 0.005 | |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0083 | 0.0061 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0083 | 0.0061 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0035 | 0.0013 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0046 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0021 | 0.0019 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0115 | 0.0095 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0047 | 0.4709 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0115 | 0.0095 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0018 | 0.1563 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0009 | 0.0003 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0185 | 0.0166 | 0.0529 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0028 | 0.0005 | 0.0049 |
Schistosoma mansoni | hypothetical protein | 0.0337 | 0.0323 | 0.0386 |
Onchocerca volvulus | 0.003 | 0.0007 | 0.0005 | |
Brugia malayi | hypothetical protein | 0.0083 | 0.0061 | 0.0056 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0018 | 0.1563 |
Trichomonas vaginalis | heat shock protein, putative | 0.0028 | 0.0005 | 0.0118 |
Mycobacterium ulcerans | oxidoreductase | 0.0083 | 0.0061 | 0.0519 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0455 | 0.0444 | 0.1445 |
Brugia malayi | MH2 domain containing protein | 0.0238 | 0.0221 | 0.0215 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0043 | 0.0021 | 0.0019 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0047 | 0.0137 |
Plasmodium falciparum | plasmepsin VI | 0.0055 | 0.0033 | 0.5369 |
Schistosoma mansoni | amine oxidase | 0.0083 | 0.0061 | 0.0068 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0185 | 0.0166 | 0.0529 |
Echinococcus multilocularis | heat shock protein | 0.0035 | 0.0013 | 0.0024 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0238 | 0.0221 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0021 | 0.0019 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0082 | 0.006 | 0.0181 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0013 | 0.1347 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0035 | 0.0013 | 0.2083 |
Echinococcus granulosus | neuropeptide s receptor | 0.0455 | 0.0444 | 0.1445 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0099 | 0.0078 | 0.0073 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0055 | 0.0033 | 0.5369 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0028 | 0.0005 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Echinococcus multilocularis | 0.0083 | 0.0061 | 0.0185 | |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0041 | 0.0018 | 0.1948 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0037 | 0.0038 |
Brugia malayi | heat shock protein 90 | 0.0035 | 0.0013 | 0.0007 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0083 | 0.0061 | 0.6291 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0082 | 0.006 | 0.0067 |
Echinococcus granulosus | Cyclin dependent kinase 2 associated protein | 0.2982 | 0.304 | 1 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0083 | 0.0061 | 1 |
Leishmania major | UDP-galactopyranose mutase | 0.0083 | 0.0061 | 0.6502 |
Echinococcus granulosus | peregrin | 0.0029 | 0.0006 | 0.0001 |
Onchocerca volvulus | 0.0082 | 0.006 | 0.018 | |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0012 | 0.0008 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0041 | 0.0019 | 0.0016 |
Echinococcus multilocularis | peregrin | 0.0029 | 0.0006 | 0.0001 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0083 | 0.0061 | 0.0068 |
Loa Loa (eye worm) | CAMK/CAMKL/CHK1 protein kinase | 0.8015 | 0.8211 | 1 |
Giardia lamblia | Kinase, PLK | 0.0115 | 0.0095 | 1 |
Schistosoma mansoni | kinase | 0.0069 | 0.0048 | 0.0051 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0083 | 0.0061 | 0.0185 |
Trypanosoma brucei | polo-like protein kinase | 0.0115 | 0.0095 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0035 | 0.0013 | 0.1354 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0046 | 0.0049 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0018 | 0.1563 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0041 | 0.0018 | 0.1563 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0055 | 0.0033 | 0.0033 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0043 | 0.0021 | 0.0191 |
Mycobacterium ulcerans | hypothetical protein | 0.0043 | 0.0021 | 0.0177 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0033 | 0.0091 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0043 | 0.0021 | 0.0191 |
Schistosoma mansoni | endoplasmin | 0.0035 | 0.0013 | 0.0008 |
Trichomonas vaginalis | heat shock protein, putative | 0.0028 | 0.0005 | 0.0118 |
Plasmodium vivax | hypothetical protein, conserved | 0.0083 | 0.0061 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0115 | 0.0095 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0043 | 0.0021 | 0.0019 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0047 | 0.005 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0041 | 0.0018 | 0.1563 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0115 | 0.0095 | 0.0108 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0035 | 0.0013 | 0.2083 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.1094 | 0.11 | 1 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0041 | 0.0019 | 0.0044 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0115 | 0.0095 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0043 | 0.0021 | 0.0015 |
Echinococcus multilocularis | heat shock protein 90 | 0.0035 | 0.0013 | 0.0024 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Plasmodium vivax | plasmepsin IV, putative | 0.0055 | 0.0033 | 0.5369 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0033 | 0.0091 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0041 | 0.0018 | 0.0013 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0021 | 0.1754 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0033 | 0.0033 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0094 | 0.0073 | 0.0223 |
Mycobacterium ulcerans | beta-lactamase | 0.0043 | 0.0021 | 0.0177 |
Trichomonas vaginalis | esterase, putative | 0.0043 | 0.0021 | 0.1851 |
Brugia malayi | Protein kinase domain containing protein | 0.8015 | 0.8211 | 0.821 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0035 | 0.0013 | 0.1354 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0185 | 0.0166 | 0.0529 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.1177 | 0.1185 | 1 |
Plasmodium vivax | endoplasmin, putative | 0.0035 | 0.0013 | 0.2083 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0043 | 0.0021 | 0.0015 |
Echinococcus granulosus | heat shock protein 90 | 0.0035 | 0.0013 | 0.0024 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0055 | 0.0033 | 0.0033 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0021 | 0.0191 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0035 | 0.0013 | 0.0832 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0115 | 0.0095 | 0.0294 |
Echinococcus granulosus | geminin | 0.0337 | 0.0323 | 0.1046 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.0053 | 0.0058 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0069 | 0.0047 | 0.005 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0115 | 0.0095 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0043 | 0.0021 | 0.0191 |
Schistosoma mansoni | deleted in oral cancer 1/cdk2-associated protein-like | 0.2982 | 0.304 | 0.3698 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0035 | 0.0013 | 0.0832 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0021 | 0.0019 |
Plasmodium vivax | hypothetical protein, conserved | 0.0043 | 0.0021 | 0.3419 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0099 | 0.0078 | 0.0073 |
Plasmodium falciparum | plasmepsin IV | 0.0055 | 0.0033 | 0.5369 |
Onchocerca volvulus | 0.0107 | 0.0086 | 0.0264 | |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0055 | 0.0033 | 0.318 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.0021 | 0.1851 |
Onchocerca volvulus | 0.0043 | 0.0021 | 0.005 | |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0043 | 0.0021 | 0.0191 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.0046 | 0.004 |
Brugia malayi | jmjC domain containing protein | 0.0094 | 0.0073 | 0.0067 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0055 | 0.0033 | 0.5369 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0043 | 0.0021 | 0.0019 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0099 | 0.0078 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0013 | 0.0008 |
Echinococcus granulosus | heat shock protein | 0.0035 | 0.0013 | 0.0024 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0018 | 0.1563 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0013 | 0.1347 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0033 | 0.0033 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0115 | 0.0095 | 0.0292 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Brugia malayi | Endoplasmin precursor | 0.0035 | 0.0013 | 0.0007 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0035 | 0.0012 | 0.0022 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0041 | 0.0019 | 0.0016 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0043 | 0.0021 | 0.1851 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0041 | 0.0018 | 0.1948 |
Brugia malayi | beta-lactamase | 0.0043 | 0.0021 | 0.0015 |
Mycobacterium leprae | conserved hypothetical protein | 0.0043 | 0.0021 | 0.3419 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0021 | 0.0191 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0009 | 0.0003 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0238 | 0.0221 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0016 | 0.0012 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0033 | 0.0091 |
Trichomonas vaginalis | heat shock protein, putative | 0.0028 | 0.0005 | 0.0118 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0016 | 0.1278 |
Trichomonas vaginalis | heat shock protein, putative | 0.0035 | 0.0013 | 0.0941 |
Leishmania major | hypothetical protein, conserved | 0.0043 | 0.0021 | 0.2223 |
Leishmania major | heat shock protein 83-1 | 0.0035 | 0.0013 | 0.1354 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0047 | 0.0137 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 31.6228 uM | PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 50.1187 uM | PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.