Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | lamin | 0.0022 | 0.3537 | 0.6116 |
Echinococcus granulosus | lamin | 0.0022 | 0.3537 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0022 | 0.3537 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0013 | 0.0375 | 0.0375 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0022 | 0.3537 | 0.3537 |
Echinococcus multilocularis | lamin | 0.0022 | 0.3537 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0022 | 0.3537 | 0.6116 |
Echinococcus granulosus | intermediate filament protein | 0.0022 | 0.3537 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0013 | 0.0375 | 0.0375 |
Echinococcus multilocularis | lamin dm0 | 0.0022 | 0.3537 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.3397 | 0.3397 |
Echinococcus multilocularis | musashi | 0.0022 | 0.3537 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0013 | 0.0375 | 0.0375 |
Onchocerca volvulus | 0.0022 | 0.3537 | 0.5 | |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0041 | 1 | 1 |
Brugia malayi | intermediate filament protein | 0.0022 | 0.3537 | 0.3537 |
Loa Loa (eye worm) | intermediate filament protein | 0.0022 | 0.3537 | 0.3537 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0375 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.3537 | 0.3537 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0041 | 1 | 1 |
Onchocerca volvulus | 0.0022 | 0.3537 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.5545 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0028 | 0.5545 | 0.5545 |
Schistosoma mansoni | lamin | 0.0022 | 0.3537 | 0.6116 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.5545 | 0.5545 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0022 | 0.3537 | 0.3537 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.