Detailed information for compound 1711477

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 650.763 | Formula: C38H42N4O6
  • H donors: 3 H acceptors: 3 LogP: 5.21 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC[C@@H](N1C[C@@H](C)[C@@H](CN(Cc2ccc(cc2)c2ccccc2)C)Oc2c(CC1=O)cc(cc2)NC(=O)Nc1ccc2c(c1)OCO2)C
  • InChi: 1S/C38H42N4O6/c1-25-20-42(26(2)23-43)37(44)18-30-17-31(39-38(45)40-32-14-16-34-35(19-32)47-24-46-34)13-15-33(30)48-36(25)22-41(3)21-27-9-11-29(12-10-27)28-7-5-4-6-8-28/h4-17,19,25-26,36,43H,18,20-24H2,1-3H3,(H2,39,40,45)/t25-,26+,36-/m1/s1
  • InChiKey: AIDUNWUCHWLKPO-QAJXPZEFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus expressed conserved protein 0.125 0.593 0.5918
Brugia malayi SH2 domain containing protein 0.125 0.593 0.5918
Entamoeba histolytica SH2-protein kinase domain containing protein 0.209 1 1
Echinococcus multilocularis tyrosine kinase 0.084 0.3944 0.3926
Schistosoma mansoni protein kinase 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Brugia malayi RhoGAP domain containing protein 0.125 0.593 0.5918
Onchocerca volvulus 0.125 0.593 0.5332
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.125 0.593 0.5918
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Echinococcus granulosus tensin C1 domain containing phosphatase 0.125 0.593 0.5918
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Loa Loa (eye worm) TK/FER protein kinase 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine kinase 0.209 1 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) TK/FER protein kinase 0.084 0.3944 0.3926
Loa Loa (eye worm) hypothetical protein 0.084 0.3944 0.3926
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Echinococcus granulosus signal transduction protein lnk realted 0.125 0.593 0.5918
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Brugia malayi Protein kinase domain containing protein 0.209 1 1
Loa Loa (eye worm) sex muscle abnormal protein 5 0.125 0.593 0.5918
Echinococcus multilocularis tyrosine protein kinase Src42A 0.209 1 1
Brugia malayi SH2 domain containing protein 0.125 0.593 0.5918
Trichomonas vaginalis AGC family protein kinase 0.084 0.3944 1
Schistosoma mansoni ephrin receptor 0.084 0.3944 0.3926
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.084 0.3944 0.3926
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase csk 0.084 0.3944 0.3926
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Echinococcus granulosus hypothetical protein 0.125 0.593 0.5918
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.125 0.593 0.5918
Onchocerca volvulus 0.084 0.3944 0.3053
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Onchocerca volvulus 0.084 0.3944 0.3053
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Loa Loa (eye worm) TK/FER protein kinase 0.209 1 1
Echinococcus granulosus tyrosine protein kinase HCK 0.084 0.3944 0.3926
Echinococcus granulosus retinal guanylyl cyclase 2 0.084 0.3944 0.3926
Schistosoma mansoni tensin 0.125 0.593 0.5918
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Echinococcus granulosus dual specificity testis-specific protein kinase 0.084 0.3944 0.3926
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.209 1 1
Loa Loa (eye worm) hypothetical protein 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Brugia malayi hypothetical protein 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.125 0.593 0.5918
Entamoeba histolytica SH2-protein kinase domain containing protein 0.125 0.593 0.593
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.084 0.3944 0.3926
Echinococcus multilocularis SH2 motif 0.125 0.593 0.5918
Loa Loa (eye worm) TK/FER protein kinase 0.209 1 1
Echinococcus granulosus activated cdc42 kinase 1 0.084 0.3944 0.3926
Schistosoma mansoni ephrin receptor 0.084 0.3944 0.3926
Schistosoma mansoni hypothetical protein 0.084 0.3944 0.3926
Plasmodium falciparum protein kinase, putative 0.084 0.3944 1
Schistosoma mansoni protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Echinococcus granulosus suppressor of cytokine signaling 7 0.125 0.593 0.5918
Entamoeba histolytica hypothetical protein 0.084 0.3944 0.3944
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Echinococcus multilocularis protein kinase 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase Blk 0.209 1 1
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Brugia malayi hypothetical protein 0.084 0.3944 0.3926
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.125 0.593 0.5332
Echinococcus multilocularis transfer RNA-Thr 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni tensin 0.125 0.593 0.5918
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.084 0.3944 0.3053
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.084 0.3944 0.3926
Brugia malayi SRC-1 0.209 1 1
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine kinase 0.209 1 1
Brugia malayi ephrin receptor 1 precursor 0.084 0.3944 0.3926
Plasmodium vivax tyrosine kinase-like protein, putative 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) TK/EGFR protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Onchocerca volvulus 0.209 1 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) TK/INSR protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Entamoeba histolytica serine/threonine kinase, putative 0.084 0.3944 0.3944
Onchocerca volvulus 0.125 0.593 0.5332
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Onchocerca volvulus 0.125 0.593 0.5332
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Echinococcus granulosus tyrosine protein kinase csk 0.084 0.3944 0.3926
Echinococcus multilocularis signal transduction protein lnk realted 0.125 0.593 0.5918
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Loa Loa (eye worm) hypothetical protein 0.084 0.3944 0.3926
Trichomonas vaginalis protein tyrosine kinase, putative 0.084 0.3944 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.125 0.593 0.5918
Loa Loa (eye worm) TK/FER protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Schistosoma mansoni protein kinase 0.084 0.3944 0.3926
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.209 1 1
Leishmania major protein kinase, putative 0.084 0.3944 1
Echinococcus granulosus tyrosine protein kinase Lyn 0.209 1 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.084 0.3944 0.3926
Entamoeba histolytica serine/threonine kinase, putative 0.084 0.3944 0.3944
Brugia malayi Receptor family ligand binding region containing protein 0.084 0.3944 0.3926
Plasmodium falciparum protein kinase, putative 0.084 0.3944 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.084 0.3944 0.3926
Echinococcus granulosus insulin growth factor 1 receptor beta 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) TK/FAK protein kinase 0.084 0.3944 0.3926
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Brugia malayi Pax transcription factor protein 2 0.0291 0.1283 0.1257
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.084 0.3944 1
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Echinococcus multilocularis c src tyrosine kinase 0.209 1 1
Loa Loa (eye worm) TK protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Brugia malayi hypothetical protein 0.125 0.593 0.5918
Echinococcus multilocularis tyrosine kinase 0.209 1 1
Plasmodium falciparum tyrosine kinase-like protein 0.084 0.3944 1
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Loa Loa (eye worm) RhoGAP domain-containing protein 0.125 0.593 0.5918
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Entamoeba histolytica SH2 domain containing protein 0.125 0.593 0.593
Loa Loa (eye worm) pax transcription factor protein 2 0.0291 0.1283 0.1257
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Trypanosoma brucei Flagellum attachment zone protein 20 0.084 0.3944 1
Entamoeba histolytica cysteine surface protein, putative 0.084 0.3944 0.3944
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.084 0.3944 1
Brugia malayi SH2 domain containing protein 0.125 0.593 0.5918
Brugia malayi SH2 domain containing protein 0.125 0.593 0.5918
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Brugia malayi RNA, U transporter 1 0.0091 0.0315 0.0287
Brugia malayi Immunoglobulin I-set domain containing protein 0.084 0.3944 0.3926
Onchocerca volvulus 0.209 1 1
Echinococcus multilocularis receptor type guanylyl cyclase 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase Fgr 0.209 1 1
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Loa Loa (eye worm) TK/ROR protein kinase 0.084 0.3944 0.3926
Loa Loa (eye worm) TK/FER protein kinase 0.209 1 1
Echinococcus granulosus tyrosine protein kinase pr2 0.084 0.3944 0.3926
Echinococcus granulosus tyrosine protein kinase Btk29A 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Echinococcus multilocularis tyrosine protein kinase csk 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.209 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Trichomonas vaginalis serine-threonine protein kinase, putative 0.084 0.3944 1
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Loa Loa (eye worm) TK protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Echinococcus granulosus SHC transforming protein 3 0.125 0.593 0.5918
Brugia malayi Probable tyrosine-protein kinase kin-31 0.084 0.3944 0.3926
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Trichomonas vaginalis CAMK family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) hypothetical protein 0.209 1 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.084 0.3944 0.3926
Loa Loa (eye worm) hypothetical protein 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Brugia malayi Tyrosine-protein kinase PR2 0.084 0.3944 0.3926
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.209 1 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.209 1 1
Echinococcus granulosus epidermal growth factor receptor 0.084 0.3944 0.3926
Trichomonas vaginalis STE family protein kinase 0.084 0.3944 1
Brugia malayi SH2 domain containing protein 0.125 0.593 0.5918
Schistosoma mansoni tyrosine kinase 0.209 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Echinococcus multilocularis tyrosine protein kinase Src42A 0.125 0.593 0.5918
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Schistosoma mansoni SH2A 0.125 0.593 0.5918
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Onchocerca volvulus 0.125 0.593 0.5332
Brugia malayi Raf kinase 0.084 0.3944 0.3926
Loa Loa (eye worm) hypothetical protein 0.084 0.3944 0.3926
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Loa Loa (eye worm) TK/DDR protein kinase 0.084 0.3944 0.3926
Onchocerca volvulus 0.209 1 1
Loa Loa (eye worm) TK/ALK protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Echinococcus multilocularis growth factor receptor bound protein 2 0.125 0.593 0.5918
Loa Loa (eye worm) TK protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Echinococcus granulosus SH2 domain containing adapter protein F 0.125 0.593 0.5918
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.209 1 1
Schistosoma mansoni protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Schistosoma mansoni serine/threonine RGC 0.084 0.3944 0.3926
Entamoeba histolytica serine/threonine kinase, putative 0.084 0.3944 0.3944
Echinococcus multilocularis tyrosine protein kinase Abl 0.209 1 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Brugia malayi cytokine inducible SH2-containing protein 5 0.125 0.593 0.5918
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Echinococcus multilocularis tyrosine protein kinase 0.084 0.3944 0.3926
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.084 0.3944 0.3926
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Loa Loa (eye worm) SH2 domain-containing protein 0.125 0.593 0.5918
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.084 0.3944 0.3926
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Loa Loa (eye worm) TK/FER protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Echinococcus multilocularis protein tyrosine kinase 0.084 0.3944 0.3926
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.084 0.3944 0.3053
Entamoeba histolytica hypothetical protein, conserved 0.084 0.3944 0.3944
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.084 0.3944 0.3926
Echinococcus multilocularis protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica hypothetical protein 0.084 0.3944 0.3944
Echinococcus multilocularis SH2 motif 0.125 0.593 0.5918
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Onchocerca volvulus Tyrosine kinase homolog 0.084 0.3944 0.3053
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.084 0.3944 0.3926
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0342 0.1531 0.1506
Echinococcus multilocularis FL cytokine receptor 0.084 0.3944 0.3926
Echinococcus granulosus tyrosine protein kinase Srms 0.209 1 1
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Echinococcus granulosus snurportin 1 0.0342 0.1531 0.1506
Loa Loa (eye worm) TK/FER protein kinase 0.209 1 1
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Echinococcus granulosus SH2 domain containing protein 7 0.125 0.593 0.5918
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.125 0.593 0.5918
Trypanosoma brucei protein kinase, putative 0.084 0.3944 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.084 0.3944 1
Giardia lamblia Kinase 0.084 0.3944 0.5
Echinococcus multilocularis dual specificity testis specific protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Trichomonas vaginalis conserved hypothetical protein 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Brugia malayi STAT protein, DNA binding domain containing protein 0.125 0.593 0.5918
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) TK/FER protein kinase 0.084 0.3944 0.3926
Brugia malayi SH2 domain containing protein 0.209 1 1
Toxoplasma gondii protein kinase 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.084 0.3944 0.3926
Plasmodium vivax protein kinase, putative 0.084 0.3944 1
Echinococcus multilocularis integrin linked protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Echinococcus multilocularis SH2 domain containing adapter protein F 0.125 0.593 0.5918
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Echinococcus multilocularis SH2 domain containing protein 7 0.125 0.593 0.5918
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Schistosoma mansoni protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica tyrosin kinase, putative 0.084 0.3944 0.3944
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.209 1 1
Loa Loa (eye worm) hypothetical protein 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Echinococcus granulosus tyrosine protein kinase Fps85D 0.209 1 1
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.084 0.3944 1
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.084 0.3944 0.3944
Echinococcus granulosus activin receptor type 0.084 0.3944 0.3926
Echinococcus granulosus tyrosine kinase 0.084 0.3944 0.3926
Loa Loa (eye worm) serine/threonine protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.084 0.3944 1
Echinococcus granulosus protein tyrosine kinase 0.084 0.3944 0.3926
Echinococcus multilocularis epidermal growth factor receptor 0.084 0.3944 0.3926
Loa Loa (eye worm) variant SH3 domain-containing protein 0.125 0.593 0.5918
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Loa Loa (eye worm) protein-tyrosine phosphatase 0.125 0.593 0.5918
Giardia lamblia Kinase, NEK 0.084 0.3944 0.5
Loa Loa (eye worm) TK protein kinase 0.084 0.3944 0.3926
Echinococcus multilocularis N chimaerin 0.125 0.593 0.5918
Onchocerca volvulus 0.084 0.3944 0.3053
Echinococcus multilocularis SHC transforming protein 3 0.125 0.593 0.5918
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.084 0.3944 0.3926
Onchocerca volvulus 0.084 0.3944 0.3053
Trypanosoma cruzi protein kinase, putative 0.084 0.3944 1
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.084 0.3944 0.3926
Echinococcus multilocularis NCK adaptor protein 0.125 0.593 0.5918
Brugia malayi tRNA modification GTPase TrmE family protein 0.125 0.593 0.5918
Onchocerca volvulus 0.084 0.3944 0.3053
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Echinococcus granulosus tyrosine protein kinase Fyn 0.209 1 1
Loa Loa (eye worm) hypothetical protein 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Echinococcus multilocularis tyrosine protein kinase Fyn 0.209 1 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) TK/ABL protein kinase 0.209 1 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) hypothetical protein 0.084 0.3944 0.3926
Schistosoma mansoni vav2 0.125 0.593 0.5918
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Echinococcus multilocularis protein KINase family member (kin 25) 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Echinococcus multilocularis suppressor of cytokine signaling 7 0.125 0.593 0.5918
Echinococcus granulosus tyrosine protein kinase Src64B 0.209 1 1
Brugia malayi C-terminal src kinase protein 1 0.084 0.3944 0.3926
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.125 0.593 0.5332
Brugia malayi Furin-like cysteine rich region family protein 0.084 0.3944 0.3926
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.125 0.593 0.5918
Echinococcus granulosus activated cdc42 kinase 1 0.084 0.3944 0.3926
Schistosoma mansoni serine/threonine protein kinase 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase pr2 0.084 0.3944 0.3926
Brugia malayi Tensin 0.125 0.593 0.5918
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Loa Loa (eye worm) SH2 domain-containing protein 0.125 0.593 0.5918
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Echinococcus granulosus c src tyrosine kinase 0.209 1 1
Schistosoma mansoni tensin-related 0.125 0.593 0.5918
Schistosoma mansoni shc transforming protein 0.125 0.593 0.5918
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.084 0.3944 0.3926
Entamoeba histolytica hypothetical protein 0.084 0.3944 0.3944
Entamoeba histolytica serine/threonine kinase, putative 0.084 0.3944 0.3944
Echinococcus multilocularis 0.125 0.593 0.5918
Schistosoma mansoni protein kinase 0.084 0.3944 0.3926
Echinococcus granulosus tyrosine protein kinase csk 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Schistosoma mansoni hypothetical protein 0.125 0.593 0.5918
Onchocerca volvulus 0.209 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.209 1 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.209 1 1
Schistosoma mansoni suppressor of cytokine signaling 0.125 0.593 0.5918
Schistosoma mansoni growth factor receptor-bound protein 0.125 0.593 0.5918
Echinococcus granulosus tyrosine protein kinase Blk 0.209 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.209 1 1
Echinococcus granulosus epidermal growth factor receptor 0.084 0.3944 0.3926
Echinococcus multilocularis tensin 0.125 0.593 0.5918
Echinococcus multilocularis tyrosine protein kinase Fyn 0.209 1 1
Leishmania major protein kinase, putative 0.084 0.3944 1
Brugia malayi Variant SH3 domain containing protein 0.125 0.593 0.5918
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.209 1 1
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.084 0.3944 0.3926
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Schistosoma mansoni protein tyrosine kinase 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase HCK 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) TK/FER protein kinase 0.209 1 1
Echinococcus granulosus NCK adaptor protein 0.125 0.593 0.5918
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni tensin-related 0.125 0.593 0.5918
Echinococcus multilocularis epidermal growth factor receptor 0.084 0.3944 0.3926
Onchocerca volvulus 0.084 0.3944 0.3053
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.125 0.593 0.5918
Loa Loa (eye worm) RGC/RGC protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis conserved hypothetical protein 0.084 0.3944 1
Entamoeba histolytica serine/threonine kinase, putative 0.084 0.3944 0.3944
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Echinococcus multilocularis natriuretic peptide receptor 1 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase ABL1 0.209 1 1
Plasmodium falciparum tyrosine kinase-like protein 0.084 0.3944 1
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Entamoeba histolytica hypothetical protein 0.084 0.3944 0.3944
Echinococcus granulosus tyrosine protein kinase Src42A 0.125 0.593 0.5918
Schistosoma mansoni serine/threonine protein kinase 0.084 0.3944 0.3926
Echinococcus granulosus tyrosine protein kinase ABL1 0.209 1 1
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.084 0.3944 0.3944
Echinococcus granulosus suppressor of cytokine signaling 6 0.125 0.593 0.5918
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Echinococcus granulosus growth factor receptor bound protein 2 0.125 0.593 0.5918
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.084 0.3944 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.209 1 1
Echinococcus granulosus SH2 motif 0.125 0.593 0.5918
Entamoeba histolytica hypothetical protein 0.084 0.3944 0.3944
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Loa Loa (eye worm) variant SH3 domain-containing protein 0.125 0.593 0.5918
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.084 0.3944 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni tyrosine kinase 0.209 1 1
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Brugia malayi Variant SH3 domain containing protein 0.125 0.593 0.5918
Trichomonas vaginalis conserved hypothetical protein 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Echinococcus granulosus tyrosine kinase 0.209 1 1
Entamoeba histolytica receptor protein kinase, putative 0.084 0.3944 0.3944
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.125 0.593 0.5918
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.084 0.3944 0.3926
Entamoeba histolytica hypothetical protein 0.084 0.3944 0.3944
Brugia malayi Variant SH3 domain containing protein 0.125 0.593 0.5918
Loa Loa (eye worm) TK/RYK protein kinase 0.084 0.3944 0.3926
Schistosoma mansoni adapter molecule crk 0.125 0.593 0.5918
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Onchocerca volvulus 0.209 1 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.125 0.593 0.5918
Loa Loa (eye worm) TK protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica serine/threonine kinase, putative 0.084 0.3944 0.3944
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Schistosoma mansoni tyrosine kinase 0.209 1 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.084 0.3944 0.3926
Schistosoma mansoni hypothetical protein 0.125 0.593 0.5918
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Echinococcus granulosus retinal guanylyl cyclase 2 0.084 0.3944 0.3926
Echinococcus granulosus SH2 motif 0.125 0.593 0.5918
Schistosoma mansoni growth factor receptor-bound protein 0.125 0.593 0.5918
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Loa Loa (eye worm) TK/FER protein kinase 0.209 1 1
Loa Loa (eye worm) TK/EPH protein kinase 0.084 0.3944 0.3926
Trypanosoma cruzi protein kinase, putative 0.084 0.3944 1
Brugia malayi Variant SH3 domain containing protein 0.125 0.593 0.5918
Echinococcus multilocularis raf serine:threonine protein kinase 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase shark 0.209 1 1
Echinococcus multilocularis tensin 0.125 0.593 0.5918
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.084 0.3944 0.3944
Echinococcus granulosus tyrosine protein kinase shark 0.209 1 1
Schistosoma mansoni protein kinase 0.084 0.3944 0.3926
Echinococcus granulosus integrin linked protein kinase 0.084 0.3944 0.3926
Echinococcus granulosus receptor type guanylyl cyclase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.125 0.593 0.5918
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.125 0.593 0.5918
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Schistosoma mansoni serine/threonine protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni tensin 0.125 0.593 0.5918
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Echinococcus granulosus raf serine:threonine protein kinase 0.084 0.3944 0.3926
Brugia malayi bone morphogenetic protein type 1 receptor 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.084 0.3944 0.3926
Loa Loa (eye worm) TK/FER protein kinase 0.209 1 1
Echinococcus multilocularis tyrosine protein kinase csk 0.084 0.3944 0.3926
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.125 0.593 0.5918
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Brugia malayi integrin-linked kinase 0.084 0.3944 0.3926
Echinococcus multilocularis retinal guanylyl cyclase 2 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Echinococcus granulosus tyrosine protein kinase 0.084 0.3944 0.3926
Loa Loa (eye worm) STAT protein 0.125 0.593 0.5918
Echinococcus multilocularis activin receptor type 0.084 0.3944 0.3926
Loa Loa (eye worm) hypothetical protein 0.084 0.3944 0.3926
Echinococcus granulosus natriuretic peptide receptor 1 0.084 0.3944 0.3926
Trichomonas vaginalis protein kinase atn1, putative 0.084 0.3944 1
Echinococcus multilocularis suppressor of cytokine signaling 6 0.125 0.593 0.5918
Onchocerca volvulus 0.084 0.3944 0.3053
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni serine/threonine protein kinase 0.084 0.3944 0.3926
Echinococcus granulosus insulin receptor 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine kinase 0.209 1 1
Loa Loa (eye worm) TK/KIN16 protein kinase 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.209 1 1
Echinococcus multilocularis SH2 motif 0.125 0.593 0.5918
Trichomonas vaginalis conserved hypothetical protein 0.084 0.3944 1
Trichomonas vaginalis conserved hypothetical protein 0.084 0.3944 1
Loa Loa (eye worm) SH2 domain-containing protein 0.125 0.593 0.5918
Brugia malayi hypothetical protein 0.209 1 1
Echinococcus multilocularis suppressor of cytokine signaling 7 0.125 0.593 0.5918
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Echinococcus granulosus ephrin type A receptor 4 A 0.084 0.3944 0.3926
Echinococcus granulosus tyrosine protein kinase csk 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Echinococcus granulosus tyrosine protein kinase Btk29A 0.209 1 1
Onchocerca volvulus 0.125 0.593 0.5332
Entamoeba histolytica tyrosin kinase, putative 0.084 0.3944 0.3944
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.209 1 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Brugia malayi SH2 domain containing protein 0.125 0.593 0.5918
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Loa Loa (eye worm) hypothetical protein 0.084 0.3944 0.3926
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica hypothetical protein 0.084 0.3944 0.3944
Brugia malayi Tyrosine-protein kinase abl-1 0.209 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.209 1 1
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Entamoeba histolytica ankyrin repeat protein 0.084 0.3944 0.3944
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni suppressor of cytokine signaling 0.125 0.593 0.5918
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Echinococcus multilocularis fibroblast growth factor receptor 4 0.084 0.3944 0.3926
Loa Loa (eye worm) TK protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis conserved hypothetical protein 0.084 0.3944 1
Echinococcus multilocularis insulin receptor 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.209 1 1
Loa Loa (eye worm) TK/CSK protein kinase 0.084 0.3944 0.3926
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.084 0.3944 1
Loa Loa (eye worm) TK protein kinase 0.084 0.3944 0.3926
Onchocerca volvulus 0.084 0.3944 0.3053
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Loa Loa (eye worm) TK/Met protein kinase 0.084 0.3944 0.3926
Echinococcus granulosus tensin 0.125 0.593 0.5918
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Trypanosoma brucei Pseudokinase, putative 0.084 0.3944 1
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.084 0.3944 0.3926
Toxoplasma gondii STE kinase 0.084 0.3944 1
Onchocerca volvulus 0.084 0.3944 0.3053
Onchocerca volvulus 0.125 0.593 0.5332
Loa Loa (eye worm) SRC-1 0.209 1 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Entamoeba histolytica receptor protein kinase, putative 0.084 0.3944 0.3944
Onchocerca volvulus 0.209 1 1
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Trichomonas vaginalis conserved hypothetical protein 0.084 0.3944 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni hypothetical protein 0.0342 0.1531 0.1506
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Loa Loa (eye worm) RGC/RGC protein kinase 0.084 0.3944 0.3926
Trichomonas vaginalis TK family protein kinase 0.084 0.3944 1
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Brugia malayi SH2 domain containing protein 0.125 0.593 0.5918
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.084 0.3944 1
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Brugia malayi Immunoglobulin I-set domain containing protein 0.084 0.3944 0.3926
Loa Loa (eye worm) TK/ACK protein kinase 0.084 0.3944 0.3926
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.209 1 1
Toxoplasma gondii protein kinase domain-containing protein 0.084 0.3944 1
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Loa Loa (eye worm) TK protein kinase 0.084 0.3944 0.3926
Echinococcus multilocularis heat shock protein 70 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Echinococcus granulosus tyrosine protein kinase Fyn 0.209 1 1
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.084 0.3944 1
Entamoeba histolytica protein kinase domain containing protein 0.084 0.3944 0.3944
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.209 1 1
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.125 0.593 0.5918
Echinococcus multilocularis retinal guanylyl cyclase 2 0.084 0.3944 0.3926
Entamoeba histolytica tyrosin kinase, putative 0.084 0.3944 0.3944
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Loa Loa (eye worm) hypothetical protein 0.084 0.3944 0.3926
Schistosoma mansoni protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica hypothetical protein 0.084 0.3944 0.3944
Entamoeba histolytica tyrosin kinase, putative 0.084 0.3944 0.3944
Loa Loa (eye worm) TK/KIN6 protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Loa Loa (eye worm) hypothetical protein 0.084 0.3944 0.3926
Entamoeba histolytica hypothetical protein 0.084 0.3944 0.3944
Schistosoma mansoni signal transduction protein lnk-related 0.125 0.593 0.5918
Brugia malayi SH2 domain containing protein 0.209 1 1
Echinococcus multilocularis tyrosine protein kinase csk 0.084 0.3944 0.3926
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.084 0.3944 0.3944
Entamoeba histolytica ankyrin repeat protein 0.084 0.3944 0.3944
Loa Loa (eye worm) TK/FER protein kinase 0.209 1 1
Loa Loa (eye worm) TK protein kinase 0.084 0.3944 0.3926
Loa Loa (eye worm) TK protein kinase 0.209 1 1
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Schistosoma mansoni nck2/grb4 0.125 0.593 0.5918
Leishmania major hypothetical protein, conserved 0.084 0.3944 1
Echinococcus granulosus tyrosine kinase 0.209 1 1
Echinococcus granulosus fibroblast growth factor receptor 4 0.084 0.3944 0.3926
Echinococcus granulosus protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Schistosoma mansoni protein kinase 0.084 0.3944 0.3926
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.084 0.3944 0.3926
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.084 0.3944 0.3926
Loa Loa (eye worm) protein kinase domain-containing protein 0.084 0.3944 0.3926
Entamoeba histolytica tyrosine kinase, putative 0.084 0.3944 0.3944
Brugia malayi Sex muscle abnormal protein 5 0.125 0.593 0.5918
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Brugia malayi protein-tyrosine kinase 0.209 1 1
Brugia malayi Protein kinase domain containing protein 0.084 0.3944 0.3926
Echinococcus multilocularis ephrin type A receptor 4 A 0.084 0.3944 0.3926
Schistosoma mansoni tyrosine-protein kinase zap-70 0.125 0.593 0.5918
Schistosoma mansoni tyrosine kinase 0.084 0.3944 0.3926
Brugia malayi Guanylyl cyclase protein 23 0.084 0.3944 0.3926
Schistosoma mansoni GTPase activating protein 0.125 0.593 0.5918
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Echinococcus granulosus kinase suppressor of Ras 1 0.084 0.3944 0.3926
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Entamoeba histolytica protein kinase, putative 0.125 0.593 0.593
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Entamoeba histolytica protein kinase, putative 0.084 0.3944 0.3944
Trichomonas vaginalis TKL family protein kinase 0.084 0.3944 1
Giardia lamblia Protein 21.1 0.084 0.3944 0.5
Loa Loa (eye worm) hypothetical protein 0.125 0.593 0.5918
Echinococcus granulosus N chimaerin 0.125 0.593 0.5918
Echinococcus granulosus retinal guanylyl cyclase 2 0.084 0.3944 0.3926
Echinococcus multilocularis activated cdc42 kinase 1 0.084 0.3944 0.3926
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.125 0.593 0.5918
Echinococcus multilocularis kinase suppressor of Ras 1 0.084 0.3944 0.3926
Echinococcus multilocularis snurportin 1 0.0342 0.1531 0.1506
Schistosoma mansoni src-type protein tyrosine kinase-related 0.084 0.3944 0.3926
Plasmodium falciparum protein kinase, putative 0.084 0.3944 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.084 0.3944 0.3926
Entamoeba histolytica hypothetical protein 0.084 0.3944 0.3944
Entamoeba histolytica hypothetical protein 0.084 0.3944 0.3944
Loa Loa (eye worm) TK/FER protein kinase 0.209 1 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.084 0.3944 0.3926
Schistosoma mansoni protein kinase 0.084 0.3944 0.3926
Brugia malayi Protein kinase domain containing protein 0.209 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.084 0.3944 0.3926
Giardia lamblia Kinase, NEK 0.084 0.3944 0.5

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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