Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | nuclear receptor NHR-88 | 0.0083 | 0.3271 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.3271 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0083 | 0.3271 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0083 | 0.3271 | 0.3271 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0083 | 0.3271 | 0.3271 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0083 | 0.3271 | 0.3271 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.3271 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0083 | 0.3271 | 0.3271 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0083 | 0.3271 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0083 | 0.3271 | 0.3271 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0083 | 0.3271 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0083 | 0.3271 | 0.3271 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0083 | 0.3271 | 0.3271 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0083 | 0.3271 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0083 | 0.3271 | 0.3271 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0083 | 0.3271 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0083 | 0.3271 | 0.5 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0083 | 0.3271 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0083 | 0.3271 | 0.3271 |
Brugia malayi | ecdysteroid receptor | 0.0083 | 0.3271 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0083 | 0.3271 | 0.3271 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0083 | 0.3271 | 0.3271 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0083 | 0.3271 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0083 | 0.3271 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0083 | 0.3271 | 0.3271 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0083 | 0.3271 | 0.3271 |
Brugia malayi | nuclear hormone receptor | 0.0083 | 0.3271 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.3271 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0083 | 0.3271 | 0.3271 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0083 | 0.3271 | 1 |
Onchocerca volvulus | 0.0083 | 0.3271 | 0.5 | |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0083 | 0.3271 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0083 | 0.3271 | 0.3271 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0083 | 0.3271 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0083 | 0.3271 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0083 | 0.3271 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0083 | 0.3271 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0083 | 0.3271 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0083 | 0.3271 | 0.3271 |
Schistosoma mansoni | thyroid hormone receptor | 0.0083 | 0.3271 | 0.3271 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0083 | 0.3271 | 0.3271 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0083 | 0.3271 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0083 | 0.3271 | 0.3271 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0083 | 0.3271 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0083 | 0.3271 | 0.3271 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0083 | 0.3271 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.3271 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0083 | 0.3271 | 0.3271 |
Schistosoma mansoni | thyroid hormone receptor | 0.0083 | 0.3271 | 0.3271 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0083 | 0.3271 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0083 | 0.3271 | 1 |
Echinococcus multilocularis | geminin | 0.0164 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.3271 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0083 | 0.3271 | 0.3271 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0083 | 0.3271 | 0.3271 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0083 | 0.3271 | 0.3271 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0083 | 0.3271 | 0.3271 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0083 | 0.3271 | 0.3271 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.3271 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0083 | 0.3271 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0083 | 0.3271 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.3271 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0083 | 0.3271 | 1 |
Brugia malayi | steroid hormone receptor | 0.0083 | 0.3271 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.3271 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0083 | 0.3271 | 0.3271 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0083 | 0.3271 | 0.3271 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0083 | 0.3271 | 0.3271 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0083 | 0.3271 | 0.3271 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0083 | 0.3271 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0083 | 0.3271 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0083 | 0.3271 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.