Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Onchocerca volvulus | Peroxidase homolog | 0.0064 | 0.416 | 0.5 |
Echinococcus multilocularis | peroxidasin | 0.0064 | 0.416 | 0.416 |
Onchocerca volvulus | Peroxidase homolog | 0.0064 | 0.416 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Onchocerca volvulus | Peroxidasin homolog | 0.0064 | 0.416 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0076 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0064 | 0.416 | 0.416 |
Brugia malayi | Peroxidasin | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0064 | 0.416 | 0.416 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0076 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0064 | 0.416 | 0.5 |
Echinococcus granulosus | peroxidasin | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Onchocerca volvulus | 0.0064 | 0.416 | 0.5 | |
Onchocerca volvulus | Dual oxidase homolog | 0.0064 | 0.416 | 0.5 |
Brugia malayi | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Schistosoma mansoni | peroxidasin | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0064 | 0.416 | 0.416 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Onchocerca volvulus | 0.0064 | 0.416 | 0.5 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Onchocerca volvulus | Peroxidasin homolog | 0.0064 | 0.416 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | RNA binding protein | 0.0076 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Brugia malayi | TAR-binding protein | 0.0076 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 0.416 | 0.416 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.416 | 0.416 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Onchocerca volvulus | 0.0064 | 0.416 | 0.5 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.0064 | 0.416 | 0.416 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0076 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0076 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0076 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 35.4813 uM | PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.