Detailed information for compound 1712431

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 490.594 | Formula: C28H34N4O4
  • H donors: 1 H acceptors: 5 LogP: 3.85 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCC(=O)N1C[C@H]([C@@H](C[C@@H]1c1ccc(cc1)C)O)n1nnc(c1)COC(=O)c1ccccc1
  • InChi: 1S/C28H34N4O4/c1-3-4-6-11-27(34)31-18-25(26(33)16-24(31)21-14-12-20(2)13-15-21)32-17-23(29-30-32)19-36-28(35)22-9-7-5-8-10-22/h5,7-10,12-15,17,24-26,33H,3-4,6,11,16,18-19H2,1-2H3/t24-,25-,26-/m1/s1
  • InChiKey: JEWFHEOZMNUBKU-TWJOJJKGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi G-protein coupled receptor 0.0024 0.0277 0.0277
Onchocerca volvulus 0.0024 0.0277 0.027
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.1254 0.0935
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.1045 0.819
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0967 0.7674
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.002
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.1065 0.2855
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Mycobacterium leprae Probable lipase LipE 0.0072 0.1254 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0409 0.0409
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.02 0.0536
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0918 0.2462
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0024 0.0277 0.0277
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.02 0.0536
Trichomonas vaginalis esterase, putative 0.0072 0.1254 0.1296
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Trypanosoma cruzi ISWI complex protein 0.0016 0.0098 0.0631
Schistosoma mansoni tar DNA-binding protein 0.0189 0.3663 0.6234
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Brugia malayi hypothetical protein 0.0024 0.0277 0.0277
Schistosoma mansoni topbp1 0.0012 0.002 0.0034
Brugia malayi Dopamine receptor 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0072 0.1254 0.1254
Schistosoma mansoni cpg binding protein 0.0028 0.0355 0.0603
Onchocerca volvulus 0.0024 0.0277 0.027
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0024 0.0277 0.0743
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0283 0.0759
Echinococcus granulosus neuropeptide s receptor 0.0024 0.0277 0.0743
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0277 0.0743
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0024 0.0277 0.0277
Echinococcus granulosus neuropeptide FF receptor 2 0.0024 0.0277 0.0743
Schistosoma mansoni opsin-like receptor 0.0024 0.0277 0.0472
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.02 0.02
Brugia malayi sulfakinin receptor protein 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0021 0.02 0.02
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0016 0.0042
Brugia malayi G protein-coupled receptor 0.0024 0.0277 0.0277
Schistosoma mansoni zinc finger protein 0.0016 0.0098 0.0167
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Schistosoma mansoni neuropeptide receptor 0.0024 0.0277 0.0472
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.1254 0.0935
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0311 0.2356
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.1018 0.8086
Echinococcus granulosus tar DNA binding protein 0.0189 0.3663 0.982
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.02 0.034
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.02 0.0536
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Toxoplasma gondii ABC1 family protein 0.0072 0.1254 1
Trichomonas vaginalis set domain proteins, putative 0.0476 0.9544 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.02 0.0536
Schistosoma mansoni biogenic amine receptor 0.0024 0.0277 0.0472
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0277 0.0743
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0277 0.0472
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.02 0.02
Brugia malayi beta-lactamase 0.0072 0.1254 0.1254
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0277 0.0743
Brugia malayi TAR-binding protein 0.0189 0.3663 0.3663
Brugia malayi GnHR receptor homolog 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0277 0.0472
Mycobacterium tuberculosis Conserved protein 0.0072 0.1254 0.0935
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0078 0.1377 0.2343
Loa Loa (eye worm) hypothetical protein 0.0021 0.02 0.02
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.02 0.0536
Echinococcus multilocularis dro:myosuppressin receptor 0.0024 0.0277 0.0743
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0277 0.0277
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0409 0.0409
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.1777 0.1777
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0277 0.0472
Echinococcus granulosus g-protein coupled receptor 0.0024 0.0277 0.0743
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.02 0.02
Brugia malayi MH2 domain containing protein 0.0121 0.2252 0.2252
Echinococcus multilocularis allatostatin A receptor 0.0024 0.0277 0.0743
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0277 0.0472
Schistosoma mansoni neuropeptide f receptor 76f 0.0024 0.0277 0.0472
Brugia malayi Pax transcription activation domain interacting protein 0.0012 0.002 0.002
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.1018 0.2729
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0024 0.0277 0.0277
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.02 0.0536
Schistosoma mansoni thyroid hormone receptor 0.0021 0.02 0.034
Brugia malayi hypothetical protein 0.0024 0.0277 0.0277
Mycobacterium tuberculosis Conserved protein 0.0072 0.1254 0.0935
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.1254 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Schistosoma mansoni DNA ligase IV 0.0012 0.002 0.0034
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.1254 0.2134
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0135 0.0229
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Schistosoma mansoni amine GPCR 0.0024 0.0277 0.0472
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0311 0.2356
Loa Loa (eye worm) hypothetical protein 0.0039 0.0583 0.0583
Onchocerca volvulus 0.0061 0.1018 0.1048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.02 0.02
Echinococcus granulosus g protein coupled receptor 0.0024 0.0277 0.0743
Loa Loa (eye worm) hypothetical protein 0.0045 0.0706 0.0706
Brugia malayi neuropeptide F receptor 0.0024 0.0277 0.0277
Echinococcus granulosus g protein coupled receptor 0.0024 0.0277 0.0743
Schistosoma mansoni tar DNA-binding protein 0.0189 0.3663 0.6234
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0148 0.0148
Brugia malayi RNA binding protein 0.0189 0.3663 0.3663
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0283 0.0759
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.051 0.0514
Leishmania major hypothetical protein, conserved 0.0072 0.1254 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.02 0.02
Brugia malayi G-protein coupled receptor 0.0024 0.0277 0.0277
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.1045 0.8304
Echinococcus multilocularis cpg binding protein 0.0032 0.0428 0.1147
Schistosoma mansoni tar DNA-binding protein 0.0189 0.3663 0.6234
Brugia malayi Melatonin receptor type 1A 0.0024 0.0277 0.0277
Schistosoma mansoni chromosome transmission fidelity factor 0.0012 0.002 0.0034
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.1777 0.1777
Mycobacterium ulcerans lipase LipD 0.0072 0.1254 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0277 0.0743
Echinococcus granulosus sex peptide receptor 0.0024 0.0277 0.0743
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0277 0.0743
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Schistosoma mansoni histamine h1 receptor 0.0024 0.0277 0.0472
Treponema pallidum DNA ligase (lig) 0.0012 0.002 0.5
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.02 0.02
Echinococcus multilocularis nibrin 0.0012 0.002 0.0054
Echinococcus multilocularis serotonin receptor 0.0024 0.0277 0.0743
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.1254 0.1254
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0277 0.0743
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.02 0.02
Onchocerca volvulus 0.0024 0.0277 0.027
Schistosoma mansoni growth hormone secretagogue receptor 0.0024 0.0277 0.0472
Brugia malayi hypothetical protein 0.0017 0.0121 0.0121
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.1254 0.2134
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0311 0.2356
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.051 1
Onchocerca volvulus 0.0072 0.1254 0.1296
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0072 0.1254 0.1254
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0277 0.0743
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0277 0.0743
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.1254 0.0935
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0277 0.0743
Brugia malayi hypothetical protein 0.0024 0.0277 0.0277
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Plasmodium vivax hypothetical protein, conserved 0.0072 0.1254 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.1254 0.0935
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0024 0.0277 0.0472
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0078 0.1377 0.3691
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.1254 0.1254
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0024 0.0277 0.0743
Schistosoma mansoni coup transcription factor 0.0021 0.02 0.034
Echinococcus multilocularis G-protein coupled receptor, putative 0.0024 0.0277 0.0743
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0 0.0001
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0277 0.0743
Echinococcus granulosus neuropeptide receptor 0.0024 0.0277 0.0743
Echinococcus multilocularis serotonin receptor 0.0024 0.0277 0.0743
Schistosoma mansoni neuropeptide receptor 0.0024 0.0277 0.0472
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0024 0.0277 0.0743
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0918 0.2462
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.1018 0.1732
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0078 0.1377 0.2343
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0277 0.0743
Echinococcus multilocularis zinc finger protein 0.0022 0.0221 0.0592
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Schistosoma mansoni topbp1 0.0012 0.002 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus multilocularis geminin 0.0174 0.3344 0.8964
Schistosoma mansoni amine GPCR 0.0024 0.0277 0.0472
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0409 0.1097
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0135 0.0361
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.02 0.0536
Loa Loa (eye worm) hypothetical protein 0.0072 0.1254 0.1254
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0024 0.0277 0.0472
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.051 1
Brugia malayi hypothetical protein 0.0012 0.002 0.002
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.1254 0.1296
Schistosoma mansoni hypothetical protein 0.0024 0.0277 0.0472
Brugia malayi Bromodomain containing protein 0.0039 0.0582 0.0582
Loa Loa (eye worm) hypothetical protein 0.0073 0.1264 0.1264
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.051 0.3967
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Schistosoma mansoni hypothetical protein 0.0297 0.5876 1
Echinococcus granulosus hypothetical protein 0.0024 0.0277 0.0743
Onchocerca volvulus 0.0024 0.0277 0.027
Echinococcus granulosus 7tm_1 domain containing protein 0.0024 0.0277 0.0743
Onchocerca volvulus 0.0024 0.0277 0.027
Echinococcus granulosus allatostatin A receptor 0.0024 0.0277 0.0743
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.1254 0.3362
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.1144 0.1144
Schistosoma mansoni tar DNA-binding protein 0.0189 0.3663 0.6234
Echinococcus granulosus serotonin receptor 0.0024 0.0277 0.0743
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0779 0.209
Brugia malayi Serotonin receptor 0.0024 0.0277 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.02 0.02
Brugia malayi Tachykinin-like peptides receptor 99D 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0277 0.0277
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.1045 0.0697
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.1018 0.1732
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.02 0.0536
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0138 0.2601 0.2601
Echinococcus granulosus nibrin 0.0012 0.002 0.0054
Echinococcus multilocularis g-protein coupled receptor 0.0024 0.0277 0.0743
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0024 0.0277 0.0743
Loa Loa (eye worm) hypothetical protein 0.0026 0.0311 0.0311
Plasmodium vivax SET domain protein, putative 0.0061 0.1018 0.8086
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0498 1 1
Echinococcus multilocularis G protein coupled receptor 139 0.0024 0.0277 0.0743
Loa Loa (eye worm) melatonin receptor type 1A 0.0024 0.0277 0.0277
Trypanosoma brucei ISWI complex protein 0.0016 0.0098 0.0631
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Onchocerca volvulus 0.0049 0.0779 0.0797
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0277 0.0743
Schistosoma mansoni hypothetical protein 0.0031 0.0409 0.0696
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0024 0.0277 0.0743
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0409 0.1097
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.2601 0.4427
Brugia malayi steroid hormone receptor 0.0021 0.02 0.02
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0135 0.0229
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.1045 0.2801
Echinococcus granulosus GPCR family 2 0.0031 0.0409 0.1097
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.2601 0.6973
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0024 0.0277 0.0743
Schistosoma mansoni neuropeptide receptor 0.0024 0.0277 0.0472
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.02 0.02
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.02 0.0536
Onchocerca volvulus 0.0024 0.0277 0.027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Schistosoma mansoni hypothetical protein 0.0024 0.0277 0.0472
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.1254 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0024 0.0277 0.0472
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0779 0.1327
Brugia malayi putative neuropeptide receptor 0.0024 0.0277 0.0277
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.1045 0.8304
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0918 0.1563
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.1254 0.1296
Onchocerca volvulus 0.0024 0.0277 0.027
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.1254 0.1296
Brugia malayi beta-lactamase family protein 0.0072 0.1254 0.1254
Trypanosoma cruzi ISWI complex protein 0.0016 0.0098 0.0631
Echinococcus granulosus dro:myosuppressin receptor 0.0024 0.0277 0.0743
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0433 0.3344
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.02 0.02
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.02 0.02
Onchocerca volvulus 0.0476 0.9544 1
Schistosoma mansoni cpg binding protein 0.0032 0.0428 0.0728
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.02 0.02
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0277 0.0743
Brugia malayi AKH receptor 0.0024 0.0277 0.0277
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.1254 0.0935
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.02 0.0536
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0409 0.0409
Brugia malayi hypothetical protein 0.0024 0.0277 0.0277
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0311 0.2356
Brugia malayi Pre-SET motif family protein 0.0418 0.836 0.836
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.1254 0.1296
Brugia malayi beta-lactamase family protein 0.0072 0.1254 0.1254
Loa Loa (eye worm) RNA binding protein 0.0189 0.3663 0.3663
Brugia malayi CXXC zinc finger family protein 0.0028 0.0355 0.0355
Mycobacterium ulcerans hypothetical protein 0.0072 0.1254 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.051 0.3967
Loa Loa (eye worm) TAR-binding protein 0.0189 0.3663 0.3663
Echinococcus granulosus neuropeptide receptor 0.0024 0.0277 0.0743
Schistosoma mansoni hypothetical protein 0.0174 0.3344 0.569
Brugia malayi nuclear receptor NHR-88 0.0021 0.02 0.02
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.051 0.356
Onchocerca volvulus 0.0021 0.02 0.0189
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0277 0.0743
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.051 0.1366
Echinococcus granulosus neuropeptide receptor A26 0.0024 0.0277 0.0743
Mycobacterium ulcerans beta-lactamase 0.0072 0.1254 1
Schistosoma mansoni opsin-like receptor 0.0024 0.0277 0.0472
Echinococcus granulosus alpha 1A adrenergic receptor 0.0024 0.0277 0.0743
Echinococcus multilocularis orexin receptor type 2 0.0024 0.0277 0.0743
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0779 0.1327
Schistosoma mansoni bromodomain containing protein 0.0066 0.114 0.194
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0277 0.0743
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0277 0.0472
Giardia lamblia Replication factor C, subunit 1 0.0012 0.002 0.5
Echinococcus granulosus G protein coupled receptor 139 0.0024 0.0277 0.0743
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.1254 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.02 0.034
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.02 0.0536
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.02 0.02
Brugia malayi hypothetical protein 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0078 0.1377 0.1377
Onchocerca volvulus 0.0024 0.0277 0.027
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0024 0.0277 0.027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.1254 1
Schistosoma mansoni hypothetical protein 0.0067 0.1144 0.1947
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0024 0.0277 0.0472
Brugia malayi Bromodomain containing protein 0.0078 0.1387 0.1387
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0779 0.209
Echinococcus granulosus peptide allatostatin:somatostatin 0.0024 0.0277 0.0743
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0277 0.0743
Schistosoma mansoni hypothetical protein 0.0031 0.0409 0.0696
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.02 0.0536
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.02 0.0536
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0277 0.0743
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0193 0.373 1
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.02 0.034
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0024 0.0277 0.0472
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.1254 0.0935
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0277 0.0472
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.051 0.3967
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.051 0.0514
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0277 0.0277
Brugia malayi Dopamine receptor protein 2 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Loa Loa (eye worm) inositol-1 0.0036 0.051 0.051
Onchocerca volvulus 0.0024 0.0277 0.027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.02 0.02
Schistosoma mansoni hypothetical protein 0.0174 0.3344 0.569
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0277 0.0472
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0277 0.0472
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus zinc finger protein 0.0022 0.0221 0.0592
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.2252 0.2252
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0277 0.0743
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0277 0.0743
Brugia malayi mbt repeat family protein 0.0049 0.0779 0.0779
Brugia malayi RNA recognition motif domain containing protein 0.0189 0.3663 0.3663
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0277 0.0277
Echinococcus granulosus replication factor c subunit 1 0.0012 0.002 0.0054
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.02 0.02
Echinococcus granulosus 7TM GPCR rhodopsin 0.0024 0.0277 0.0743
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.1045 0.1778
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Onchocerca volvulus 0.0072 0.1254 0.1296
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.02 0.02
Brugia malayi putative neuropeptide receptor NPR1 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus somatostatin receptor 0.0024 0.0277 0.0743
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.02 0.02
Brugia malayi mbt repeat family protein 0.0049 0.0779 0.0779
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0283 0.0482
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0409 0.1097
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0016 0.0042
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.02 0.034
Onchocerca volvulus 0.0024 0.0277 0.027
Echinococcus multilocularis somatostatin receptor 0.0024 0.0277 0.0743
Brugia malayi Inositol-1 0.0036 0.051 0.051
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.096 0.2574
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0277 0.0743
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.1048 0.1784
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus histone lysine methyltransferase setb 0.0078 0.1377 0.3691
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0277 0.0472
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0067 0.1144 0.1144
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0024 0.0277 0.0277
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0024 0.0277 0.0743
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0779 0.209
Brugia malayi ORL1-like opioid receptor 0.0024 0.0277 0.0277
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0779 0.209
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0277 0.0743
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0277 0.0472
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0277 0.0472
Brugia malayi hypothetical protein 0.0024 0.0277 0.0277
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.02 0.0189
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0918 0.2462
Echinococcus multilocularis neuropeptide FF receptor 2 0.0024 0.0277 0.0743
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.1254 0.0935
Brugia malayi hypothetical protein 0.0012 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0277 0.0472
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.1777 0.1777
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.051 0.3967
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0311 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0418 0.836 0.836
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.02 0.034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.1254 0.3362
Brugia malayi larval opioid receptor 0.0024 0.0277 0.0277
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.02 0.034
Onchocerca volvulus 0.0024 0.0277 0.027
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.002
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0277 0.0743
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.002
Brugia malayi hypothetical protein 0.0024 0.0277 0.0277
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.1254 0.1296
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.02 0.034
Echinococcus multilocularis replication factor c subunit 1 0.0012 0.002 0.0054
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0532 0.1426
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.1045 0.2801
Schistosoma mansoni hypothetical protein 0.0016 0.0098 0.0167
Schistosoma mansoni hypothetical protein 0.0024 0.0277 0.0472
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0024 0.0277 0.0743
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0311 1
Echinococcus granulosus geminin 0.0174 0.3344 0.8964
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.2601 0.4427
Brugia malayi PHD-finger family protein 0.0027 0.0333 0.0333
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0355 0.0355
Schistosoma mansoni zinc finger protein 0.0022 0.0221 0.0376
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.051 0.0514
Onchocerca volvulus 0.0024 0.0277 0.027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0277 0.0472
Echinococcus granulosus cpg binding protein 0.0032 0.0428 0.1147
Brugia malayi G protein-coupled receptor F59B2.13 0.0024 0.0277 0.0277
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.02 0.0189
Brugia malayi ecdysteroid receptor 0.0021 0.02 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0277 0.0472
Schistosoma mansoni inositol monophosphatase 0.0036 0.051 0.0867
Echinococcus multilocularis neuropeptide s receptor 0.0024 0.0277 0.0743
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0779 0.0797
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.021 0.021
Echinococcus multilocularis GPCR, family 2 0.0031 0.0409 0.1097
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0024 0.0277 0.0743
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0277 0.0743
Brugia malayi nuclear hormone receptor 0.0021 0.02 0.02
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0277 0.0743
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.02 0.0536
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.1065 0.2855
Schistosoma mansoni amine GPCR 0.0024 0.0277 0.0472
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.2601 0.6973
Loa Loa (eye worm) hypothetical protein 0.0098 0.1777 0.1777
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0779 0.1327
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0024 0.0277 0.0743
Schistosoma mansoni amine GPCR 0.0024 0.0277 0.0472
Mycobacterium tuberculosis Possible penicillin-binding protein 0.046 0.922 1
Brugia malayi Serotonin receptor 0.0024 0.0277 0.0277
Schistosoma mansoni nuclear hormone receptor 0.0021 0.02 0.034
Echinococcus granulosus FTZ F1 alpha 0.0021 0.02 0.0536
Schistosoma mansoni hypothetical protein 0.0021 0.021 0.0358
Onchocerca volvulus 0.0024 0.0277 0.027
Mycobacterium tuberculosis Conserved protein 0.0072 0.1254 0.0935
Brugia malayi hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.2601 0.6973
Schistosoma mansoni hypothetical protein 0.0024 0.0277 0.0472
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0277 0.0472
Mycobacterium leprae conserved hypothetical protein 0.0072 0.1254 1
Schistosoma mansoni amine GPCR 0.0024 0.0277 0.0472
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0277 0.0472
Onchocerca volvulus 0.0024 0.0277 0.027
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.051 0.1366
Loa Loa (eye worm) hypothetical protein 0.0021 0.02 0.02
Schistosoma mansoni thyroid hormone receptor 0.0021 0.02 0.034
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0193 0.373 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.1254 0.1254
Echinococcus granulosus orexin receptor type 2 0.0024 0.0277 0.0743
Schistosoma mansoni myosin xvIII 0.0024 0.0277 0.0472
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.02 0.02
Echinococcus multilocularis sex peptide receptor 0.0024 0.0277 0.0743
Schistosoma mansoni opsin-like receptor 0.0024 0.0277 0.0472
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.02 0.0536
Schistosoma mansoni tar DNA-binding protein 0.0189 0.3663 0.6234
Brugia malayi Dopamine receptor protein 1 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0021 0.02 0.02
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.02 0.02
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.02 0.034
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0012 0.002 0.002
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.02 0.0189
Onchocerca volvulus 0.0072 0.1254 0.1296
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.02 0.0536
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.02 0.0536
Brugia malayi topoisomerase 0.0012 0.002 0.002
Schistosoma mansoni inositol monophosphatase 0.0036 0.051 0.0867
Schistosoma mansoni biogenic amine receptor 0.0024 0.0277 0.0472
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0409 0.1097
Loa Loa (eye worm) hypothetical protein 0.0042 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0024 0.0277 0.0472
Onchocerca volvulus 0.0024 0.0277 0.027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0277 0.0472
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0024 0.0277 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.02 0.02
Echinococcus multilocularis tar DNA binding protein 0.0189 0.3663 0.982
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0311 0.2356
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.02 0.02
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0135 0.0361
Schistosoma mansoni hypothetical protein 0.0012 0.0016 0.0027
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0918 0.2462
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0189 0.3663 0.3663
Chlamydia trachomatis DNA ligase 0.0012 0.002 0.5
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0277 0.0743
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0024 0.0277 0.0472
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.02 0.02
Brugia malayi hypothetical protein 0.0024 0.0277 0.0277
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.1045 0.1778
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0779 0.0779
Brugia malayi hypothetical protein 0.0024 0.0277 0.0277
Echinococcus granulosus tachykinin peptides receptor 99D 0.0024 0.0277 0.0743
Schistosoma mansoni hypothetical protein 0.0031 0.0409 0.0696
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0277 0.0743
Loa Loa (eye worm) hypothetical protein 0.0021 0.02 0.02
Loa Loa (eye worm) beta-lactamase 0.0072 0.1254 0.1254
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Loa Loa (eye worm) hypothetical protein 0.0021 0.02 0.02
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.02 0.034
Brugia malayi RE15519p 0.0024 0.0277 0.0277
Loa Loa (eye worm) TYRA-2 protein 0.0024 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0021 0.02 0.02
Schistosoma mansoni cpg binding protein 0.0032 0.0428 0.0728
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0277 0.0743
Echinococcus granulosus fmrfamide receptor 0.0024 0.0277 0.0743
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0138 0.2601 0.2601
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0024 0.0277 0.0472
Brugia malayi DKFZp564C0469 protein 0.0012 0.002 0.002
Brugia malayi Pre-SET motif family protein 0.0061 0.1018 0.1018
Loa Loa (eye worm) hypothetical protein 0.0056 0.0918 0.0918
Echinococcus multilocularis neuropeptide receptor A26 0.0024 0.0277 0.0743
Schistosoma mansoni neuropeptide receptor 0.0024 0.0277 0.0472
Loa Loa (eye worm) hypothetical protein 0.0072 0.1254 0.1254
Schistosoma mansoni adenoreceptor 0.0024 0.0277 0.0472
Onchocerca volvulus 0.0024 0.0277 0.027
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.2601 0.6973
Loa Loa (eye worm) MBCTL1 0.0056 0.0918 0.0918
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.2252 0.2252
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.1045 0.8304
Schistosoma mansoni alpha-1 adrenergic receptor 0.0024 0.0277 0.0472
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0409 0.0409
Loa Loa (eye worm) hypothetical protein 0.0072 0.1254 0.1254
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0918 0.0918
Echinococcus granulosus g protein coupled receptor 0.0024 0.0277 0.0743
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0024 0.0277 0.0743
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.051 0.3967
Schistosoma mansoni hypothetical protein 0.0031 0.0409 0.0696
Onchocerca volvulus 0.0028 0.0355 0.0351
Loa Loa (eye worm) hypothetical protein 0.0049 0.0779 0.0779
Loa Loa (eye worm) hypothetical protein 0.0024 0.0277 0.0277
Leishmania major hypothetical protein, conserved 0.0026 0.0311 0.1841
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0277 0.0743
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0277 0.0472
Brugia malayi hypothetical protein 0.0026 0.0311 0.0311
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.2601 0.4427
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0277 0.0743
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0024 0.0277 0.0277
Schistosoma mansoni biogenic amine receptor 0.0024 0.0277 0.0472
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0277 0.0743
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0532 0.1426
Brugia malayi neuropeptide F receptor 0.0024 0.0277 0.0277
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0024 0.0277 0.0277
Onchocerca volvulus Neuropeptide F receptor homolog 0.0024 0.0277 0.027
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.1254 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.1045 0.8304
Onchocerca volvulus 0.0024 0.0277 0.027

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 8.9125 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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