Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0028 | 0.4732 | 0.4732 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0678 | 0.0678 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.4732 | 0.4732 |
Brugia malayi | hypothetical protein | 0.0037 | 0.726 | 0.726 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.4732 | 0.4732 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.726 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.4593 | 0.4593 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.4732 | 0.4732 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.4732 | 0.4732 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.726 | 0.726 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.4732 | 0.4732 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.4732 | 0.4732 |
Onchocerca volvulus | 0.0028 | 0.4732 | 1 | |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.1218 | 0.1218 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0678 | 0.0678 |
Echinococcus multilocularis | lamin | 0.0028 | 0.4732 | 0.4732 |
Echinococcus granulosus | lamin | 0.0028 | 0.4732 | 0.4732 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.726 | 0.726 |
Schistosoma mansoni | lamin | 0.0028 | 0.4732 | 0.4732 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.0028 | 0.4732 | 1 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 1 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0816 | 0.0816 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.4732 | 0.4732 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.4732 | 0.4732 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0816 | 0.0816 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.1218 | 0.1218 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.726 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.726 | 0.5 |
Schistosoma mansoni | lamin | 0.0028 | 0.4732 | 0.4732 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.726 | 0.726 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0816 | 0.0816 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.726 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.726 | 0.726 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.4732 | 0.4732 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.