Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0107 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0011 | 0.0011 |
Plasmodium falciparum | amino acid transporter, putative | 0.0069 | 0.0107 | 1 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0069 | 0.0107 | 0.0693 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0096 | 0.016 | 1 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0069 | 0.0107 | 0.0905 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0058 | 0.0373 |
Plasmodium vivax | amine transporter, putative | 0.0069 | 0.0107 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0181 | 0.033 | 0.033 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0006 | 0.5 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0006 | 0.0039 |
Onchocerca volvulus | 0.0343 | 0.0653 | 0.0552 | |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0006 | 0.0039 |
Echinococcus granulosus | FTZ F1 alpha | 0.0343 | 0.0653 | 0.4231 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0181 | 0.033 | 0.2139 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0011 | 0.1039 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0069 | 0.0107 | 0.0693 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0069 | 0.0107 | 0.0693 |
Schistosoma mansoni | thyroid hormone receptor | 0.0343 | 0.0653 | 0.4231 |
Onchocerca volvulus | Bile acid receptor homolog | 0.5028 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0162 | 0.0291 | 0.1888 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.0653 | 0.0653 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0058 | 0.0058 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0343 | 0.0653 | 0.0653 |
Brugia malayi | conserved hypotetical protein | 0.0162 | 0.0291 | 0.0291 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0343 | 0.0653 | 0.0552 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0343 | 0.0653 | 0.0653 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0086 | 0.0141 | 0.8798 |
Mycobacterium tuberculosis | Probable reductase | 0.0086 | 0.0141 | 0.8798 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0162 | 0.0291 | 0.0291 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0058 | 0.0487 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0181 | 0.033 | 0.033 |
Brugia malayi | hypothetical protein | 0.0069 | 0.0107 | 0.0107 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.0307 | 0.1991 |
Brugia malayi | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0107 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0086 | 0.0141 | 0.8798 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0096 | 0.0621 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.033 | 0.033 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0343 | 0.0653 | 0.5526 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.0307 | 0.1991 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0107 | 0.0107 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0026 | 0.0171 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0069 | 0.0107 | 0.0693 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0011 | 0.5396 |
Brugia malayi | hypothetical protein | 0.0181 | 0.033 | 0.033 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0343 | 0.0653 | 0.4231 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0069 | 0.0107 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0038 | 0.0044 | 0.0044 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0011 | 0.2522 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0343 | 0.0653 | 0.0653 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0162 | 0.0291 | 0.0291 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0069 | 0.0107 | 0.0905 |
Loa Loa (eye worm) | hypothetical protein | 0.0357 | 0.068 | 0.068 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.0096 | 0.0096 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0011 | 1 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0069 | 0.0107 | 0.0693 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Brugia malayi | ecdysone receptor | 0.0162 | 0.0291 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.033 | 0.033 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0162 | 0.0291 | 0.1888 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0107 | 0.0107 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0343 | 0.0653 | 0.4231 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0343 | 0.0653 | 0.0653 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0343 | 0.0653 | 0.5526 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.0096 | 0.0096 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0343 | 0.0653 | 0.0653 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.033 | 0.033 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0069 | 0.0107 | 0.0693 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0107 | 0.0107 |
Brugia malayi | nuclear receptor RXR | 0.0162 | 0.0291 | 0.0291 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0006 | 0.0006 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0006 | 0.0051 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0343 | 0.0653 | 0.4231 |
Echinococcus granulosus | muscleblind protein | 0.015 | 0.0267 | 0.1731 |
Brugia malayi | glutathione reductase | 0.0038 | 0.0044 | 0.0044 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0343 | 0.0653 | 0.5526 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0069 | 0.0107 | 0.0693 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0343 | 0.0653 | 0.5526 |
Brugia malayi | tailless protein | 0.0162 | 0.0291 | 0.0291 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.0096 | 0.0811 |
Loa Loa (eye worm) | hydrolase | 0.0995 | 0.1953 | 0.1953 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0789 | 0.1543 | 1 |
Echinococcus granulosus | serotonin transporter | 0.0069 | 0.0107 | 0.0693 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.033 | 0.033 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0038 | 0.0044 | 1 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0026 | 0.5999 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0069 | 0.0107 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0026 | 0.0026 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0011 | 0.0072 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0096 | 0.0621 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0343 | 0.0653 | 0.0653 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0069 | 0.0107 | 0.0693 |
Plasmodium vivax | glutathione reductase, putative | 0.0038 | 0.0044 | 0.412 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0343 | 0.0653 | 0.0653 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0162 | 0.0291 | 0.2466 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0086 | 0.0141 | 0.8798 |
Toxoplasma gondii | thioredoxin reductase | 0.0038 | 0.0044 | 0.412 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0162 | 0.0291 | 0.1888 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0026 | 0.0171 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0162 | 0.0291 | 0.1888 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0069 | 0.0107 | 0.0905 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0343 | 0.0653 | 0.4231 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0026 | 0.0026 |
Leishmania major | trypanothione reductase | 0.0038 | 0.0044 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0162 | 0.0291 | 0.2466 |
Onchocerca volvulus | 0.0162 | 0.0291 | 0.0186 | |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0343 | 0.0653 | 0.4231 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0107 | 0.0107 |
Toxoplasma gondii | hypothetical protein | 0.0069 | 0.0107 | 1 |
Brugia malayi | Muscleblind-like protein | 0.015 | 0.0267 | 0.0267 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0069 | 0.0107 | 0.0693 |
Plasmodium vivax | hypothetical protein, conserved | 0.0069 | 0.0107 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0006 | 0.1365 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0069 | 0.0107 | 0.0693 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0015 | 1 |
Leishmania major | importin beta-1 subunit, putative | 0.0024 | 0.0015 | 0.3508 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0343 | 0.0653 | 0.5526 |
Plasmodium falciparum | glutathione reductase | 0.0038 | 0.0044 | 0.412 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0343 | 0.0653 | 0.0653 |
Onchocerca volvulus | 0.0162 | 0.0291 | 0.0186 | |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0343 | 0.0653 | 0.5526 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0026 | 0.2471 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0162 | 0.0291 | 0.0291 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0343 | 0.0653 | 0.0653 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0343 | 0.0653 | 0.4231 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0107 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0162 | 0.0291 | 0.0291 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0058 | 0.0487 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0162 | 0.0291 | 0.1888 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0162 | 0.0291 | 0.1888 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.0096 | 0.0096 |
Schistosoma mansoni | nuclear receptor | 0.0162 | 0.0291 | 0.1888 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0096 | 0.016 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0343 | 0.0653 | 0.4231 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0343 | 0.0653 | 0.0653 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0343 | 0.0653 | 0.5526 |
Brugia malayi | RNA, U transporter 1 | 0.0083 | 0.0133 | 0.0133 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0343 | 0.0653 | 0.0653 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.0653 | 0.0653 |
Loa Loa (eye worm) | serotonin transporter b | 0.0069 | 0.0107 | 0.0107 |
Trypanosoma brucei | trypanothione reductase | 0.0038 | 0.0044 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.0096 | 0.0621 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0107 | 0.0107 |
Echinococcus multilocularis | muscleblind protein 1 | 0.015 | 0.0267 | 0.2261 |
Schistosoma mansoni | thyroid hormone receptor | 0.0343 | 0.0653 | 0.4231 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0162 | 0.0291 | 0.0291 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0181 | 0.033 | 0.2139 |
Schistosoma mansoni | nuclear receptor | 0.0162 | 0.0291 | 0.1888 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.0096 | 0.0096 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Brugia malayi | hydrolase, alpha/beta fold family protein | 0.0494 | 0.0954 | 0.0954 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0096 | 0.016 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0343 | 0.0653 | 0.0653 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0024 | 0.0015 | 0.3508 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0069 | 0.0107 | 0.0693 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0011 | 0.2522 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0015 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0343 | 0.0653 | 0.4231 |
Brugia malayi | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0107 | 0.0107 |
Schistosoma mansoni | hypothetical protein | 0.031 | 0.0588 | 0.3809 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0011 | 0.2522 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0343 | 0.0653 | 0.4231 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0069 | 0.0107 | 0.0107 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0058 | 0.0373 |
Schistosoma mansoni | nuclear hormone receptor | 0.0162 | 0.0291 | 0.1888 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0162 | 0.0291 | 0.2466 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0015 | 1 |
Echinococcus granulosus | geminin | 0.017 | 0.0307 | 0.1991 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0096 | 0.016 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0162 | 0.0291 | 0.2466 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0058 | 0.0373 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0343 | 0.0653 | 0.0653 |
Plasmodium falciparum | thioredoxin reductase | 0.0038 | 0.0044 | 0.412 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0058 | 0.0373 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0357 | 0.068 | 0.4408 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0026 | 0.5999 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.0267 | 0.0267 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0026 | 0.2471 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0357 | 0.068 | 0.068 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0181 | 0.033 | 0.033 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0011 | 0.1039 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0181 | 0.033 | 0.2793 |
Schistosoma mansoni | ran | 0.0021 | 0.0011 | 0.0072 |
Trichomonas vaginalis | importin beta-1, putative | 0.0024 | 0.0015 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.031 | 0.0588 | 0.4975 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0181 | 0.033 | 0.033 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0162 | 0.0291 | 0.0186 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0086 | 0.0141 | 0.8798 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0069 | 0.0107 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.5028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0107 | 0.0107 |
Brugia malayi | steroid hormone receptor | 0.0343 | 0.0653 | 0.0653 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0069 | 0.0107 | 0.0693 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.0653 | 0.0653 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0343 | 0.0653 | 0.4231 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0011 | 0.0094 |
Echinococcus multilocularis | geminin | 0.017 | 0.0307 | 0.26 |
Brugia malayi | hypothetical protein | 0.0181 | 0.033 | 0.033 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.0653 | 0.0653 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0026 | 0.0224 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0343 | 0.0653 | 0.4231 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0086 | 0.0141 | 0.8798 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0006 | 0.0562 |
Brugia malayi | nuclear receptor NHR-88 | 0.0343 | 0.0653 | 0.0653 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0038 | 0.0045 | 0.0381 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0162 | 0.0291 | 0.1888 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0006 | 0.0039 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0162 | 0.0291 | 0.2466 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0343 | 0.0653 | 0.4231 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0162 | 0.0291 | 0.0291 |
Brugia malayi | nuclear hormone receptor | 0.0162 | 0.0291 | 0.0291 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0162 | 0.0291 | 0.1888 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0006 | 0.1365 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0011 | 0.1039 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0162 | 0.0291 | 0.0186 |
Schistosoma mansoni | coup transcription factor | 0.0343 | 0.0653 | 0.4231 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0107 | 0.0107 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0006 | 0.0562 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0038 | 0.0044 | 0.412 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0608 | 0.1181 | 1 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0357 | 0.068 | 0.068 |
Plasmodium falciparum | transporter, putative | 0.0069 | 0.0107 | 1 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0069 | 0.0107 | 0.5 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0162 | 0.0291 | 0.0291 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0343 | 0.0653 | 0.0653 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0096 | 0.0621 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0107 | 0.0107 |
Schistosoma mansoni | nuclear hormone receptor | 0.0162 | 0.0291 | 0.1888 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0343 | 0.0653 | 0.4231 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.033 | 0.033 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0343 | 0.0653 | 0.4231 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0038 | 0.0045 | 0.0292 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0357 | 0.068 | 0.4408 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0107 | 0.0107 |
Loa Loa (eye worm) | glutathione reductase | 0.0038 | 0.0044 | 0.0044 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0006 | 0.0562 |
Brugia malayi | nuclear receptor NHR-67 | 0.0162 | 0.0291 | 0.0291 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0038 | 0.0044 | 0.0044 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0181 | 0.033 | 0.2139 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0343 | 0.0653 | 0.0653 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0058 | 0.0373 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0026 | 0.2471 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.0653 | 0.0653 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0343 | 0.0653 | 0.0653 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0096 | 0.0621 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0069 | 0.0107 | 0.0693 |
Brugia malayi | nuclear hormone receptor | 0.0343 | 0.0653 | 0.0653 |
Loa Loa (eye worm) | DR-78 | 0.0162 | 0.0291 | 0.0291 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0038 | 0.0044 | 0.2749 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0162 | 0.0291 | 0.0291 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0069 | 0.0107 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.0653 | 0.0653 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.0653 | 0.0653 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0162 | 0.0291 | 0.1888 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0162 | 0.0291 | 0.0291 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0343 | 0.0653 | 0.0653 |
Toxoplasma gondii | hypothetical protein | 0.0069 | 0.0107 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0789 | 0.1543 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0343 | 0.0653 | 0.0653 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0343 | 0.0653 | 0.0653 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0357 | 0.068 | 0.5757 |
Onchocerca volvulus | Epoxide hydrolase 1 homolog | 0.0995 | 0.1953 | 0.1866 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0343 | 0.0653 | 0.0653 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.031 | 0.0588 | 0.0588 |
Echinococcus granulosus | snurportin 1 | 0.031 | 0.0588 | 0.3809 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.0096 | 0.0096 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0343 | 0.0653 | 0.5526 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0162 | 0.0291 | 0.1888 |
Loa Loa (eye worm) | hypothetical protein | 0.0357 | 0.068 | 0.068 |
Schistosoma mansoni | ran | 0.0021 | 0.0011 | 0.0072 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0357 | 0.068 | 0.4408 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0011 | 0.2522 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0357 | 0.068 | 0.5757 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0011 | 0.0011 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0343 | 0.0653 | 0.0552 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0107 | 0.0107 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0006 | 0.1365 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0006 | 0.5 |
Brugia malayi | RNA binding protein | 0.0064 | 0.0096 | 0.0096 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0343 | 0.0653 | 0.0653 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0343 | 0.0653 | 0.0653 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0291 | 0.0291 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0343 | 0.0653 | 0.5526 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0096 | 0.0621 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0343 | 0.0653 | 0.4231 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0343 | 0.0653 | 0.4231 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0006 | 0.1365 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0069 | 0.0107 | 0.0693 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0011 | 0.5396 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0006 | 0.0375 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0343 | 0.0653 | 0.0653 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0343 | 0.0653 | 0.0653 |
Brugia malayi | nuclear receptor NHR-88 | 0.0162 | 0.0291 | 0.0291 |
Echinococcus multilocularis | muscleblind protein | 0.015 | 0.0267 | 0.2261 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0058 | 0.0058 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0069 | 0.0107 | 0.0693 |
Echinococcus multilocularis | serotonin transporter | 0.0069 | 0.0107 | 0.0905 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0357 | 0.068 | 0.4408 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.