Detailed information for compound 171319

Basic information

Technical information
  • TDR Targets ID: 171319
  • Name: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(2-ethylbut anoylamino)propanoyl]amino]-4-oxo-4-pyrrolidi n-1-ylbutanoyl]amino]-4-hydroxy-4-oxobutanoyl ]amino]-4-methylpentanoic acid
  • MW: 583.674 | Formula: C27H45N5O9
  • H donors: 6 H acceptors: 9 LogP: 0.54 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 3
  • SMILES: CCC(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CC(C)C)CC(=O)O)CC(=O)N1CCCC1)C)CC
  • InChi: 1S/C27H45N5O9/c1-6-17(7-2)24(37)28-16(5)23(36)29-18(13-21(33)32-10-8-9-11-32)25(38)30-19(14-22(34)35)26(39)31-20(27(40)41)12-15(3)4/h15-20H,6-14H2,1-5H3,(H,28,37)(H,29,36)(H,30,38)(H,31,39)(H,34,35)(H,40,41)/t16-,18-,19-,20-/m0/s1
  • InChiKey: VRSTZDVILMURLO-LEAZDLGRSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(2-ethylbutanoylamino)propanoyl]amino]-4-oxo-4-pyrrolidin-1-yl-butanoyl]amino]-4-hydroxy-4-oxo-butanoyl]amino]-4-methyl-pentanoic acid
  • (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-ethyl-1-oxobutyl)amino]-1-oxopropyl]amino]-1,4-dioxo-4-(1-pyrrolidinyl)butyl]amino]-4-hydroxy-1,4-dioxobutyl]amino]-4-methylpentanoic acid
  • (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(2-ethylbutanoylamino)propanoyl]amino]-4-keto-4-pyrrolidino-butanoyl]amino]-4-hydroxy-4-keto-butanoyl]amino]-4-methyl-valeric acid
  • (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-ethyl-1-oxobutyl)amino]-1-oxopropyl]amino]-1,4-dioxo-4-1-pyrrolidinylbutyl]amino]-4-hydroxy-1,4-dioxobutyl]amino]-4-methylpentanoic acid
  • (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(2-ethylbutanoylamino)propanoyl]amino]-4-keto-4-pyrrolidin-1-yl-butanoyl]amino]-4-hydroxy-4-keto-butanoyl]amino]-4-methyl-valeric acid
  • 2-(3-Carboxy-2-{2-[2-(2-ethyl-butyrylamino)-propionylamino]-4-oxo-4-pyrrolidin-1-yl-butyrylamino}-propionylamino)-4-methyl-pentanoic acid
  • AIDS-191869
  • AIDS191869

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis ribonucleoside-diphosphate reductase alpha chain, putative 0.0239 0.0349 0.8219
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0029 0.0022 0.0036
Mycobacterium leprae RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDF (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R2F PROTEIN) 0.0028 0.002 0.0449
Onchocerca volvulus 0.0142 0.0198 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0029 0.0544
Schistosoma mansoni neuropeptide F-like receptor 0.0142 0.0198 0.0938
Brugia malayi hypothetical protein 0.0019 0.0006 0.0009
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0004 0.0004
Echinococcus multilocularis GPCR, family 2 0.0068 0.0082 0.0082
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.005 0.117
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0016 0.0001 0.0001
Echinococcus granulosus expressed protein 0.0033 0.0028 0.0028
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0142 0.0198 0.0938
Brugia malayi cathepsin L-like precursor 0.0016 0.0002 0.0002
Echinococcus multilocularis nmda type glutamate receptor 0.0105 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0016 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0025
Plasmodium falciparum calcium-dependent protein kinase 1 0.0029 0.0022 0.0359
Echinococcus multilocularis expressed conserved protein 0.0183 0.0262 0.0262
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0007 0.0011
Plasmodium falciparum calcium-dependent protein kinase 5 0.0029 0.0022 0.0359
Plasmodium vivax lysine--tRNA ligase, putative 0.0021 0.0009 0.0136
Leishmania major GTP-binding protein, putative 0.0021 0.0009 0.0169
Loa Loa (eye worm) glutamate receptor 0.0015 0 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.005 0.11
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.004 0.0934
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.0424 1
Onchocerca volvulus 0.0142 0.0198 0.0318
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0016 0.0072
Loa Loa (eye worm) hypothetical protein 0.0357 0.0533 0.0858
Echinococcus granulosus General substrate transporter 0.008 0.0102 0.0102
Plasmodium vivax proline--tRNA ligase, putative 0.0033 0.0028 0.0446
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0074 0.0349
Loa Loa (eye worm) G-protein coupled receptor 0.0142 0.0198 0.0319
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.005 0.11
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0142 0.0198 0.0938
Schistosoma mansoni survival motor neuron protein 0.0102 0.0136 0.0646
Echinococcus multilocularis muscleblind protein 0.0147 0.0206 0.0206
Toxoplasma gondii lysine-tRNA ligase 0.0021 0.0009 0.0208
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0022 0.0488
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0142 0.0198 0.0198
Echinococcus multilocularis sterol regulatory element binding protein 0.0084 0.0107 0.0107
Brugia malayi nuclear receptor NHR-67 0.0126 0.0173 0.0277
Onchocerca volvulus 0.0142 0.0198 0.0318
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0126 0.0173 0.0173
Leishmania major protein kinase, putative 0.0029 0.0022 0.0414
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0103 0.0138 0.3526
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Trypanosoma brucei glucose transporter 1E 0.0029 0.0022 0.0389
Onchocerca volvulus 0.0024 0.0014 0.0022
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0053 0.0059 0.133
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0142 0.0198 0.0318
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0032 0.0593
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0142 0.0198 0.0938
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0014 0.0304
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0016 0.0072
Entamoeba histolytica protein kinase, putative 0.0029 0.0022 0.052
Echinococcus granulosus tm gpcr rhodopsin 0.0142 0.0198 0.0198
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.005 0.11
Brugia malayi Nuclear hormone receptor-like 1 0.0326 0.0485 0.078
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0452 0.0681 0.0681
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0024 0.0014 0.0304
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0032 0.015
Echinococcus granulosus cytochrome P450 2K1 0.0035 0.0032 0.0032
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0047 0.0221
Plasmodium vivax calcium-dependent protein kinase, putative 0.0029 0.0022 0.0359
Plasmodium falciparum protein kinase 7 0.0264 0.0388 0.6526
Loa Loa (eye worm) glutamate receptor 1 0.0029 0.0023 0.0037
Echinococcus granulosus ribonucleoside diphosphate reductase subunit 0.0081 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0502 0.0759 0.1222
Brugia malayi Cathepsin L-like precursor 0.0024 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0052
Echinococcus granulosus serotonin transporter 0.0146 0.0205 0.0205
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0424 1
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0042 0.0972
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0032 0.0802
Echinococcus granulosus fmrfamide receptor 0.0142 0.0198 0.0198
Plasmodium falciparum transporter, putative 0.0025 0.0016 0.0243
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0016 0.0001 0.0001
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0198 0.0285 0.1353
Brugia malayi MH2 domain containing protein 0.0253 0.0372 0.0598
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0151 0.0212 0.5463
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0029 0.0022 0.0022
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0021 0.0514
Echinococcus multilocularis mitogen activated protein kinase 0.0058 0.0067 0.0067
Onchocerca volvulus 0.0016 0.0002 0.0002
Mycobacterium tuberculosis Conserved protein 0.0035 0.0032 0.0802
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0035 0.0032 0.0641
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0014 0.0242
Echinococcus granulosus tar DNA binding protein 0.0062 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0452 0.0681 0.1096
Echinococcus granulosus g protein coupled receptor 0.0142 0.0198 0.0198
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0452 0.0681 0.1096
Loa Loa (eye worm) hypothetical protein 0.0326 0.0485 0.0781
Echinococcus granulosus neuropeptides capa receptor 0.0142 0.0198 0.0198
Onchocerca volvulus Cathepsin L homolog 0.0024 0.0014 0.0022
Schistosoma mansoni ATP-binding cassette transporter 0.0029 0.0023 0.0106
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0452 0.0681 0.1096
Schistosoma mansoni cpg binding protein 0.0048 0.0052 0.0243
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0126 0.0173 0.0277
Trypanosoma cruzi cruzipain precursor, putative 0.0024 0.0014 0.0257
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0032 0.0051
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0022 0.0403
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0068 0.0082 0.0082
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0029 0.0047
Plasmodium falciparum proline--tRNA ligase 0.0033 0.0028 0.0446
Leishmania major cathepsin L-like protease 0.0024 0.0014 0.0257
Toxoplasma gondii hypothetical protein 0.0025 0.0016 0.0372
Leishmania major glucose transporter, lmgt2 0.0029 0.0022 0.0403
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Brugia malayi Cytochrome P450 family protein 0.0111 0.0151 0.0242
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Onchocerca volvulus Bile acid receptor homolog 0.4 0.6212 1
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0021 0.0009 0.0069
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0021 0.0374
Onchocerca volvulus 0.0019 0.0007 0.0011
Brugia malayi MAP kinase sur-1 0.0058 0.0067 0.0107
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0021 0.0009 0.0142
Brugia malayi Serotonin receptor 0.0142 0.0198 0.0318
Echinococcus granulosus Niemann Pick C1 protein 0.0279 0.0411 0.0411
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0452 0.0681 0.1096
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0024 0.0014 0.0217
Echinococcus multilocularis serotonin receptor 0.0142 0.0198 0.0198
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0068 0.0082 0.0082
Echinococcus granulosus calcium dependent protein kinase 0.0027 0.0019 0.0019
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain 0.0028 0.002 0.0351
Echinococcus multilocularis g protein coupled receptor 0.0142 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0051
Loa Loa (eye worm) nuclear receptor NHR-67 0.0126 0.0173 0.0278
Schistosoma mansoni glutaminase 0.0273 0.0402 0.1907
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0213 0.031 0.0498
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0142 0.0198 0.0318
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0015 0 0.0001
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Schistosoma mansoni hypothetical protein 0.0068 0.0082 0.0388
Loa Loa (eye worm) latrophilin receptor protein 2 0.0068 0.0082 0.0132
Brugia malayi Cathepsin L-like precursor 0.0016 0.0002 0.0002
Schistosoma mansoni lysyl-tRNA synthetase 0.0021 0.0009 0.0042
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0022 0.0527
Loa Loa (eye worm) hypothetical protein 0.0195 0.0281 0.0452
Brugia malayi AMP-binding enzyme family protein 0.0047 0.005 0.008
Leishmania major ribonucleoside-diphosphate reductase small chain, putative 0.0081 0.0104 0.194
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Brugia malayi Dopamine receptor protein 1 0.0142 0.0198 0.0318
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0042 0.0042 0.0972
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0032 0.0799
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0033
Leishmania major eukaryotic initiation factor 4a, putative 0.0103 0.0138 0.2576
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0009 0.0212
Loa Loa (eye worm) G-protein coupled receptor 0.0142 0.0198 0.0319
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0032 0.0728
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0035 0.0032 0.0641
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0014 0.0242
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0035 0.0032 0.0799
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0032 0.0788
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0452 0.0681 0.3231
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0136 0.0219
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0035 0.0032 0.0641
Echinococcus granulosus nuclear receptor nhr 48 0.0126 0.0173 0.0173
Leishmania major cysteine peptidase A (CPA) 0.0024 0.0014 0.0257
Loa Loa (eye worm) neuropeptide F receptor 0.0142 0.0198 0.0319
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0016 0.0001 0.0015
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0058 0.0067 0.125
Brugia malayi MH2 domain containing protein 0.0017 0.0004 0.0005
Mycobacterium leprae putative cytochrome p450 0.0035 0.0032 0.0799
Giardia lamblia Lysyl-tRNA synthetase 0.0021 0.0009 0.019
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0002 0.0006
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0142 0.0198 0.0938
Loa Loa (eye worm) MH2 domain-containing protein 0.0253 0.0372 0.0599
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0126 0.0173 0.0277
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Trypanosoma brucei THT1 - hexose transporter, putative 0.0029 0.0022 0.0389
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0016 0.0001 0.0002
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0084 0.0107 0.0173
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0024 0.0014 0.0304
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0028 0.0045
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0093 0.0122 0.0122
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0046 0.0049 0.1137
Loa Loa (eye worm) hypothetical protein 0.0029 0.0022 0.0035
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.004 0.0917
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0029 0.0022 0.04
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0035 0.0032 0.0641
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0028 0.002 0.0471
Brugia malayi Glutamate receptor 2 precursor 0.0029 0.0023 0.0036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0424 1
Echinococcus multilocularis sex peptide receptor 0.0142 0.0198 0.0198
Brugia malayi serine/threonine-protein kinase plk-2 0.0077 0.0097 0.0155
Schistosoma mansoni amine GPCR 0.0142 0.0198 0.0938
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0035 0.0032 0.0799
Brugia malayi neuropeptide F receptor 0.0142 0.0198 0.0318
Echinococcus multilocularis cysteine protease 0.0024 0.0014 0.0014
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0032 0.0802
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0002
Echinococcus multilocularis dro:myosuppressin receptor 0.0142 0.0198 0.0198
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0014 0.0242
Mycobacterium tuberculosis Probable transcriptional regulatory protein NrdR 0.0019 0.0007 0.0063
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain, putative 0.0081 0.0104 0.1928
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0142 0.0198 0.0318
Brugia malayi MH1 domain containing protein 0.0017 0.0004 0.0005
Trypanosoma brucei lanosterol synthase 0.0046 0.0049 0.0893
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0024 0.0014 0.0023
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0046 0.0049 0.0079
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0013 0.0272
Brugia malayi hypothetical protein 0.0142 0.0198 0.0318
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0007 0.0099
Schistosoma mansoni cpg binding protein 0.0051 0.0056 0.0263
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0022 0.0344
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Brugia malayi Cathepsin L-like precursor 0.0024 0.0014 0.0022
Onchocerca volvulus Cathepsin L homolog 0.0024 0.0014 0.0022
Schistosoma mansoni biogenic amine receptor 0.0142 0.0198 0.0938
Brugia malayi hypothetical protein 0.0029 0.0022 0.0034
Leishmania major cathepsin L-like protease 0.0024 0.0014 0.0257
Echinococcus multilocularis Smad4 0.0017 0.0004 0.0004
Echinococcus granulosus G protein coupled receptor 139 0.0142 0.0198 0.0198
Schistosoma mansoni lysyl-tRNA synthetase 0.0021 0.0009 0.0042
Giardia lamblia Prenyltransferase 0.0042 0.0042 0.0972
Brugia malayi hypothetical protein 0.0019 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0047 0.0221
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0042 0.0972
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0103 0.0138 0.3236
Loa Loa (eye worm) melatonin receptor type 1A 0.0142 0.0198 0.0319
Echinococcus multilocularis neuropeptides capa receptor 0.0142 0.0198 0.0198
Echinococcus multilocularis neuropeptide receptor A26 0.0583 0.0885 0.0885
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0146 0.0205 0.0329
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0035 0.0032 0.0799
Plasmodium falciparum cysteine proteinase falcipain 3 0.0024 0.0014 0.0217
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0066 0.0081 0.0081
Brugia malayi G-protein coupled receptor 0.0142 0.0198 0.0318
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0103 0.0138 0.2576
Schistosoma mansoni hypothetical protein 0.0035 0.0032 0.0149
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0097 0.2255
Toxoplasma gondii protein kinase, putative 0.0264 0.0388 1
Trypanosoma cruzi ribonucleoside-diphosphate reductase small chain, putative 0.0081 0.0104 0.194
Trypanosoma brucei glucose transporter, putative 0.0029 0.0022 0.0389
Schistosoma mansoni biogenic amine receptor 0.0142 0.0198 0.0938
Leishmania major eukaryotic initiation factor 4a, putative 0.0103 0.0138 0.2576
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0066 0.0081 0.0081
Schistosoma mansoni glucose transport protein 0.0093 0.0122 0.0577
Entamoeba histolytica serine/threonine protein kinase, putative 0.0077 0.0097 0.2269
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0028 0.002 0.0454
Schistosoma mansoni RAR-like nuclear receptor 0.0452 0.0681 0.3231
Trypanosoma cruzi cysteine peptidase, putative 0.0024 0.0014 0.0257
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0142 0.0198 0.0318
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0004 0.0004
Loa Loa (eye worm) TYRA-2 protein 0.0142 0.0198 0.0319
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0032 0.0512
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0103 0.0138 0.3223
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0142 0.0198 0.0198
Schistosoma mansoni glutamate receptor kainate 0.0029 0.0023 0.0106
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0452 0.0681 0.1096
Loa Loa (eye worm) ribonucleotide reductase M2 B 0.0081 0.0104 0.0167
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0 0.0001
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1658 0.2561 0.2561
Echinococcus multilocularis glutamate receptor 2 0.0045 0.0046 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0022 0.0488
Echinococcus multilocularis RUN 0.0019 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0014 0.0304
Echinococcus granulosus sterol regulatory element binding protein 0.0084 0.0107 0.0107
Echinococcus granulosus Nuclear hormone receptor HR96 0.0126 0.0173 0.0173
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0009 0.0138
Echinococcus granulosus mitogen activated protein kinase 0.0058 0.0067 0.0067
Schistosoma mansoni alpha-1 adrenergic receptor 0.0142 0.0198 0.0938
Brugia malayi nuclear hormone receptor family member odr-7 0.0126 0.0173 0.0277
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0142 0.0198 0.0198
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0007 0.0007
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0025 0.0016 0.0016
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0258 0.0379 0.7103
Echinococcus multilocularis microtubule associated protein 2 0.1366 0.2106 0.2106
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0103 0.0138 0.2565
Entamoeba histolytica hypothetical protein 0.0021 0.0009 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0097 0.2255
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0035 0.0032 0.0799
Leishmania major lysyl-tRNA synthetase, putative 0.0021 0.0009 0.0166
Echinococcus multilocularis rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Echinococcus granulosus glutamate NMDA receptor subunit 0.0029 0.0023 0.0023
Echinococcus granulosus neuropeptide receptor 0.0142 0.0198 0.0198
Echinococcus multilocularis Niemann Pick C1 protein 0.0195 0.0281 0.0281
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0016 0.0016
Brugia malayi Cathepsin L-like precursor 0.0024 0.0014 0.0022
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0035 0.0032 0.0591
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0032 0.015
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0042 0.0042 0.0694
Brugia malayi hypothetical protein 0.0142 0.0198 0.0318
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0452 0.0681 0.1096
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0452 0.0681 0.1096
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.004 0.0917
Plasmodium falciparum calcium-dependent protein kinase 4 0.0029 0.0022 0.0359
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0452 0.0681 0.1096
Schistosoma mansoni rab6-interacting 0.0019 0.0007 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0035 0.0032 0.0799
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0142 0.0198 0.0938
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0027 0.0497
Trichomonas vaginalis rotamase, putative 0.0032 0.0027 0.0606
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0035 0.0032 0.0799
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0029 0.0022 0.0022
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0022 0.0397
Trypanosoma brucei glucose transporter, putative 0.0029 0.0022 0.0389
Plasmodium falciparum protein kinase 6 0.0396 0.0594 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0018 0.0005 0.0096
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0424 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0032 0.0633
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0015 0 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0032 0.0579
Leishmania major cytochrome p450-like protein 0.0035 0.0032 0.0591
Brugia malayi Cam kinase protein 1 0.0029 0.0022 0.0035
Plasmodium falciparum calcium-dependent protein kinase 3 0.0029 0.0022 0.0359
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0142 0.0198 0.0198
Echinococcus multilocularis cysteine protease 0.0024 0.0014 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0035 0.0032 0.0799
Schistosoma mansoni rotamase 0.0033 0.0028 0.0131
Loa Loa (eye worm) glutamate receptor 2 0.0029 0.0023 0.0037
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0035 0.0032 0.0641
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.004 0.0064
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0126 0.0173 0.0818
Loa Loa (eye worm) norepinephrine transporter 0.0146 0.0205 0.033
Plasmodium falciparum mitogen-activated protein kinase 2 0.0151 0.0212 0.3565
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0035 0.0032 0.0641
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0142 0.0198 0.0198
Echinococcus granulosus sex peptide receptor 0.0142 0.0198 0.0198
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.005 0.117
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0035 0.0032 0.0799
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0004 0.0016
Brugia malayi Dopamine receptor 0.0142 0.0198 0.0318
Onchocerca volvulus Cathepsin F homolog 0.0024 0.0014 0.0022
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0029 0.0022 0.0022
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0035 0.0032 0.0641
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0195 0.4778
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0042 0.0042 0.0042
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0093 0.0122 0.0122
Toxoplasma gondii cytochrome p450 superfamily protein 0.0035 0.0032 0.0794
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.004 0.0917
Schistosoma mansoni thyroid hormone receptor 0.0452 0.0681 0.3231
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0024 0.0014 0.0217
Brugia malayi hypothetical protein 0.0142 0.0198 0.0318
Brugia malayi Doublecortin family protein 0.0019 0.0007 0.0011
Plasmodium vivax amine transporter, putative 0.0025 0.0016 0.0243
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0029 0.0702
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0424 1
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0029 0.0022 0.0359
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0142 0.0198 0.0198
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0031 0.0025 0.0395
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0357 0.0533 0.0857
Schistosoma mansoni hypothetical protein 0.0019 0.0007 0.0032
Trypanosoma cruzi ribonucleoside-diphosphate reductase small chain, putative 0.0081 0.0104 0.194
Toxoplasma gondii facilitative glucose transporter GT1 0.0093 0.0122 0.3122
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0029 0.0022 0.0022
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0126 0.0173 0.0277
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0142 0.0198 0.0938
Brugia malayi CHE-14 protein 0.0084 0.0107 0.0172
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.005 0.1325
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Trypanosoma cruzi cysteine peptidase, putative 0.0024 0.0014 0.0257
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0081 0.038
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0195 0.5545
Brugia malayi hypothetical protein 0.0142 0.0198 0.0318
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0021 0.0009 0.0069
Echinococcus granulosus neuropeptide Y receptor 0.0142 0.0198 0.0198
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0038 0.0868
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0045 0.0046 0.0046
Onchocerca volvulus 0.0025 0.0016 0.0024
Echinococcus granulosus neuropeptide receptor 0.0142 0.0198 0.0198
Schistosoma mansoni patched 1 0.0084 0.0107 0.0507
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0016 0.0001 0.0015
Brugia malayi hypothetical protein 0.0326 0.0485 0.078
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0016 0.0372
Schistosoma mansoni neuropeptide receptor 0.0142 0.0198 0.0938
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Schistosoma mansoni neuropeptide f receptor 76f 0.0142 0.0198 0.0938
Brugia malayi putative neuropeptide receptor 0.0142 0.0198 0.0318
Schistosoma mansoni cytochrome P450 0.0035 0.0032 0.0149
Brugia malayi Calcitonin receptor-like protein seb-1 0.0213 0.031 0.0498
Plasmodium falciparum amino acid transporter, putative 0.0025 0.0016 0.0243
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.005 0.1325
Brugia malayi Nuclear hormone receptor-like 1 0.0326 0.0485 0.078
Brugia malayi putative neuropeptide receptor NPR1 0.0142 0.0198 0.0318
Leishmania major cathepsin L-like protease 0.0024 0.0014 0.0257
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0142 0.0198 0.0938
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.005 0.0932
Loa Loa (eye worm) hypothetical protein 0.0182 0.0261 0.042
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0326 0.0485 0.2301
Echinococcus granulosus allatostatin A receptor 0.0142 0.0198 0.0198
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0042 0.0042 0.0694
Brugia malayi ecdysone receptor 0.0126 0.0173 0.0277
Echinococcus multilocularis rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0473 0.0715 0.1151
Brugia malayi Papain family cysteine protease containing protein 0.0024 0.0014 0.0022
Trypanosoma cruzi lanosterol synthase, putative 0.0046 0.0049 0.0907
Entamoeba histolytica hypothetical protein 0.0023 0.0013 0.029
Brugia malayi GnHR receptor homolog 0.0142 0.0198 0.0318
Entamoeba histolytica hypothetical protein 0.0079 0.0099 0.2337
Leishmania major farnesyltransferase beta subunit 0.0042 0.0042 0.0787
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0058 0.0067 0.1701
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0077 0.0097 0.1807
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0025
Trypanosoma cruzi lanosterol synthase, putative 0.0046 0.0049 0.0907
Leishmania major glucose transporter, lmgt3 0.0029 0.0022 0.0403
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.005 0.11
Schistosoma mansoni glutamate receptor kainate 0.0029 0.0023 0.0106
Echinococcus granulosus cpg binding protein 0.0051 0.0056 0.0056
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0077 0.0097 0.0097
Onchocerca volvulus 0.0142 0.0198 0.0318
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0081 0.1871
Echinococcus granulosus neuropeptide receptor A26 0.0583 0.0885 0.0885
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0023
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0126 0.0173 0.0173
Mycobacterium ulcerans hypothetical protein 0.0047 0.005 0.11
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0046 0.0049 0.1154
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0016 0.0072
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0014 0.0065
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0033 0.0028 0.0511
Echinococcus granulosus nmda type glutamate receptor 0.0105 0.0141 0.0141
Brugia malayi Glutamate receptor 1 precursor 0.0029 0.0023 0.0036
Loa Loa (eye worm) hypothetical protein 0.4 0.6212 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0035 0.0032 0.0799
Schistosoma mansoni nuclear receptor nhr-48 0.0126 0.0173 0.0818
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0046 0.0049 0.0232
Echinococcus multilocularis thyroid hormone receptor alpha 0.0452 0.0681 0.0681
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Toxoplasma gondii ribonucleoside-diphosphate reductase small subunit 0.0081 0.0104 0.2651
Mycobacterium tuberculosis Conserved protein 0.0035 0.0032 0.0802
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0194
Treponema pallidum ATP-dependent RNA helicase 0.0103 0.0138 0.1303
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0042 0.0042 0.0042
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0014 0.0304
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0452 0.0681 0.1096
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0035 0.0032 0.0641
Schistosoma mansoni neuropeptide F-like receptor 0.0142 0.0198 0.0938
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0452 0.0681 0.1096
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0035 0.0032 0.0799
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0035 0.0032 0.0641
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0142 0.0198 0.0198
Brugia malayi RNA, U transporter 1 0.0081 0.0103 0.0164
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0326 0.0485 0.0485
Brugia malayi Cathepsin L-like precursor 0.0024 0.0014 0.0022
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0045 0.0046 0.0046
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0016 0.0072
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0022 0.0488
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0142 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0025
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.002 0.0091
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Echinococcus multilocularis cathepsin L cysteine protease 0.0024 0.0014 0.0014
Leishmania major cytochrome p450-like protein 0.0035 0.0032 0.0591
Echinococcus multilocularis FTZ F1 alpha 0.0452 0.0681 0.0681
Brugia malayi RNA binding protein 0.0062 0.0074 0.0118
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0016 0.0072
Plasmodium falciparum importin beta, putative 0.0028 0.0021 0.0335
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0035 0.0032 0.0641
Echinococcus multilocularis g protein coupled receptor 0.0142 0.0198 0.0198
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.005 0.0932
Echinococcus multilocularis somatostatin receptor 0.0142 0.0198 0.0198
Brugia malayi neuropeptide F receptor 0.0142 0.0198 0.0318
Loa Loa (eye worm) nuclear hormone receptor 0.0126 0.0173 0.0278
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0452 0.0681 0.0681
Echinococcus granulosus thyroid hormone receptor alpha 0.0126 0.0173 0.0173
Schistosoma mansoni opsin-like receptor 0.0142 0.0198 0.0938
Schistosoma mansoni hypothetical protein 0.0146 0.0204 0.0968
Loa Loa (eye worm) hypothetical protein 0.0452 0.0681 0.1096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Plasmodium vivax vivapain-2 0.0024 0.0014 0.0217
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0032 0.0802
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0029 0.0702
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0103 0.0138 0.0651
Trichomonas vaginalis CAMK family protein kinase 0.0029 0.0022 0.0502
Schistosoma mansoni glutamate receptor AMPA 0.0029 0.0023 0.0106
Brugia malayi beta-lactamase family protein 0.0035 0.0032 0.0051
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0452 0.0681 0.3231
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0035 0.0032 0.0641
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0452 0.0681 0.1096
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0007 0.0007
Echinococcus granulosus cathepsin l1 0.0016 0.0002 0.0002
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0004 0.0004
Schistosoma mansoni nuclear hormone receptor 0.0126 0.0173 0.0818
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0025 0.0016 0.0016
Echinococcus multilocularis neuropeptide Y receptor 0.0142 0.0198 0.0198
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0142 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0051
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0452 0.0681 0.0681
Echinococcus multilocularis serotonin transporter 0.0146 0.0205 0.0205
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0029 0.0476
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.004 0.004
Leishmania major glucose transporter/membrane transporter D2, putative 0.0029 0.0022 0.0403
Echinococcus multilocularis g-protein coupled receptor 0.0142 0.0198 0.0198
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0016 0.0001 0.0001
Echinococcus granulosus microtubule associated protein 2 0.1366 0.2106 0.2106
Echinococcus multilocularis calcium dependent protein kinase 0.0027 0.0019 0.0019
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0025
Schistosoma mansoni glutamate receptor NMDA 0.0045 0.0046 0.0218
Loa Loa (eye worm) ribonucleoside-diphosphate reductase large subunit 0.0258 0.0379 0.061
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0016 0.0072
Mycobacterium ulcerans glutaminase 0.0273 0.0402 1
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0097 0.2255
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0009 0.0154
Brugia malayi ribonucleoside-diphosphate reductase large chain, putative 0.0258 0.0379 0.0609
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0029 0.0544
Echinococcus granulosus rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0452 0.0681 0.1096
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0016 0.0072
Echinococcus multilocularis smad 0.0017 0.0004 0.0004
Onchocerca volvulus 0.0016 0.0002 0.0002
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0452 0.0681 0.1096
Trypanosoma cruzi cysteine peptidase, putative 0.0024 0.0014 0.0257
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0073 0.0091 0.1702
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0032 0.0032
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0042 0.0042 0.0774
Trypanosoma brucei glucose transporter 2A 0.0029 0.0022 0.0389
Brugia malayi hypothetical protein 0.0502 0.0759 0.1221
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0032 0.0802
Loa Loa (eye worm) solute carrier family 6 member 4 0.0146 0.0205 0.033
Brugia malayi steroid hormone receptor 0.0452 0.0681 0.1096
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0045 0.0046 0.0046
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0142 0.0198 0.0938
Brugia malayi hypothetical protein 0.0142 0.0198 0.0318
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0093 0.0122 0.0122
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0032 0.0644
Loa Loa (eye worm) glutaminase 0.0273 0.0402 0.0647
Schistosoma mansoni importin beta-1 0.0028 0.0021 0.0098
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0326 0.0485 0.2301
Brugia malayi latrophilin 2 splice variant baaae 0.0146 0.0204 0.0328
Onchocerca volvulus 0.0024 0.0014 0.0022
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0126 0.0173 0.0173
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0016 0.0016
Brugia malayi Cathepsin L-like precursor 0.0016 0.0002 0.0002
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0452 0.0681 0.3231
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0032 0.0728
Plasmodium falciparum sentrin-specific protease 1 0.0046 0.0049 0.0812
Onchocerca volvulus 0.0142 0.0198 0.0318
Loa Loa (eye worm) neuropeptide F receptor 0.0142 0.0198 0.0319
Brugia malayi hypothetical protein 0.0142 0.0198 0.0318
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Loa Loa (eye worm) hypothetical protein 0.0452 0.0681 0.1096
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0007 0.0007
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0022 0.0383
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0195 0.5545
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0033 0.0028 0.0683
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Mycobacterium leprae conserved hypothetical protein 0.0019 0.0007 0.0063
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0058 0.0067 0.125
Plasmodium vivax vivapain-2 0.0024 0.0014 0.0217
Brugia malayi photoreceptor-specific nuclear receptor 0.0452 0.0681 0.1096
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Echinococcus granulosus 7TM GPCR rhodopsin 0.0142 0.0198 0.0198
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0014 0.0242
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0025 0.0016 0.0016
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0195 0.0281 0.6612
Brugia malayi beta-lactamase 0.0035 0.0032 0.0051
Mycobacterium tuberculosis Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (ribonucleotide reductase) 0.0086 0.0111 0.3084
Mycobacterium leprae Probable lipase LipE 0.0035 0.0032 0.0802
Plasmodium vivax ribonucleoside-diphosphate reductase small chain, putative 0.0081 0.0104 0.173
Echinococcus granulosus Nuclear hormone receptor HR96 0.0126 0.0173 0.0173
Echinococcus granulosus tm gpcr rhodopsin 0.0142 0.0198 0.0198
Echinococcus multilocularis glutamate receptor 2 0.0029 0.0023 0.0023
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0016 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Echinococcus multilocularis sentrin specific protease 1 0.0046 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0052
Schistosoma mansoni growth hormone secretagogue receptor 0.0142 0.0198 0.0938
Schistosoma mansoni lipoxygenase 0.0116 0.0157 0.0746
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Onchocerca volvulus 0.0102 0.0136 0.0219
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0068 0.0082 0.0082
Echinococcus granulosus neuropeptide Y receptor 0.0142 0.0198 0.0198
Trypanosoma brucei THT1 - hexose transporter, putative 0.0029 0.0022 0.0389
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0452 0.0681 0.1096
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0054 0.0253
Leishmania major glucose transporter, lmgt1 0.0029 0.0022 0.0403
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0074 0.0349
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0865 0.1324 0.2132
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0032 0.0644
Plasmodium vivax hexose transporter 0.0093 0.0122 0.2038
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0009 0.0169
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0032 0.0728
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0452 0.0681 0.0681
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0028 0.002 0.0032
Brugia malayi AKH receptor 0.0142 0.0198 0.0318
Schistosoma mansoni hypothetical protein 0.0081 0.0103 0.0485
Loa Loa (eye worm) beta-lactamase 0.0035 0.0032 0.0052
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0032 0.0052
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0027 0.0497
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain 0.0081 0.0104 0.1928
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0029 0.0702
Echinococcus multilocularis geminin 0.0873 0.1337 0.1337
Brugia malayi eukaryotic initiation factor 4A 0.0103 0.0138 0.0221
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.0097 0.0457
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0029 0.0729
Onchocerca volvulus 0.0142 0.0198 0.0318
Mycobacterium ulcerans ribonucleotide-diphosphate reductase subunit beta 0.0028 0.002 0.0337
Brugia malayi Cytochrome P450 family protein 0.0053 0.0059 0.0095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0014 0.0304
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0035 0.0032 0.0799
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0032 0.0728
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0142 0.0198 0.0198
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0067 0.1555
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0016 0.0024
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0007 0.0007
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0452 0.0681 0.0681
Toxoplasma gondii hypothetical protein 0.0025 0.0016 0.0372
Onchocerca volvulus 0.0035 0.0032 0.0051
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0029 0.0029
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0014 0.0065
Plasmodium falciparum calcium-dependent protein kinase 2 0.0029 0.0022 0.0359
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0035 0.0032 0.0799
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0047 0.0075
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0126 0.0173 0.0173
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0024 0.0014 0.0023
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0013 0.0231
Schistosoma mansoni steroid hormone receptor ad4bp 0.0452 0.0681 0.3231
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0097 0.2255
Trypanosoma brucei glucose transporter, putative 0.0029 0.0022 0.0389
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0029 0.0022 0.055
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0033 0.0028 0.0511
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0014 0.0242
Loa Loa (eye worm) hypothetical protein 0.0326 0.0485 0.0781
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0066 0.0081 0.221
Schistosoma mansoni ran 0.0021 0.0009 0.0043
Loa Loa (eye worm) RNA binding protein 0.0062 0.0074 0.0119
Brugia malayi nuclear receptor RXR 0.0326 0.0485 0.078
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0077 0.0097 0.0156
Schistosoma mansoni smad 0.0017 0.0004 0.0016
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0016 0.0243
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.0042 0.0972
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0011
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0452 0.0681 0.0681
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Brugia malayi Nuclear hormone receptor-like 1 0.0452 0.0681 0.1096
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0097 0.2255
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0014 0.0322
Echinococcus multilocularis vesicular acetylcholine transporter 0.0865 0.1324 0.1324
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.004 0.0188
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0142 0.0198 0.0198
Trypanosoma brucei glucose transporter, putative 0.0029 0.0022 0.0389
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0142 0.0198 0.0319
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0105 0.0141 0.0141
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0021 0.0021
Onchocerca volvulus 0.0142 0.0198 0.0318
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Brugia malayi orphan nuclear receptor NR2E1 0.0126 0.0173 0.0277
Loa Loa (eye worm) cytochrome P450 0.0035 0.0032 0.0051
Loa Loa (eye worm) hypothetical protein 0.0146 0.0205 0.033
Leishmania major cathepsin L-like protease 0.0024 0.0014 0.0257
Echinococcus multilocularis ecdysone induced protein 78C 0.0452 0.0681 0.0681
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0029 0.0022 0.0359
Trypanosoma cruzi hexose transporter, putative 0.0016 0.0001 0.002
Leishmania major cathepsin L-like protease 0.0024 0.0014 0.0257
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0047 0.0047
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0028 0.002 0.0032
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0009 0.0009
Echinococcus granulosus neuropeptide s receptor 0.0583 0.0885 0.0885
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0081 0.038
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0022 0.0488
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0014
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0035 0.0032 0.0799
Loa Loa (eye worm) hypothetical protein 0.0102 0.0137 0.022
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Loa Loa (eye worm) CXXC zinc finger family protein 0.0048 0.0052 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0038 0.0868
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0042 0.0042 0.0068
Trypanosoma cruzi protein farnesyltransferase, putative 0.0042 0.0042 0.0787
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0014 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0107 0.2506
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0068 0.0082 0.0082
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0116 0.0157 0.0157
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0067 0.125
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0042 0.0042 0.0199
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0016 0.0016
Echinococcus multilocularis serotonin receptor 0.0142 0.0198 0.0198
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0045 0.0046 0.0046
Echinococcus granulosus g-protein coupled receptor 0.0142 0.0198 0.0198
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0126 0.0173 0.0173
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.004 0.0743
Echinococcus multilocularis neuropeptide receptor 0.0142 0.0198 0.0198
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0016
Echinococcus multilocularis cpg binding protein 0.0051 0.0056 0.0056
Schistosoma mansoni coup transcription factor 0.0452 0.0681 0.3231
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0074 0.0119
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0035 0.0032 0.0799
Onchocerca volvulus 0.0142 0.0198 0.0318
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0035 0.0032 0.0641
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0142 0.0198 0.0198
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0025 0.0016 0.0024
Onchocerca volvulus 0.0142 0.0198 0.0318
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.004 0.004
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0126 0.0173 0.0818
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0029 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0683 0.1041 0.4943
Onchocerca volvulus 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0049 0.0079
Echinococcus granulosus dnaJ subfamily B 0.0683 0.1041 0.1041
Loa Loa (eye worm) hypothetical protein 0.0068 0.0082 0.0132
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0029 0.0476
Echinococcus multilocularis ribonucleoside diphosphate reductase subunit 0.0081 0.0104 0.0104
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0016 0.0001 0.0019
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Schistosoma mansoni hypothetical protein 0.0102 0.0136 0.0646
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0424 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0058 0.0067 0.125
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0029 0.0022 0.0036
Schistosoma mansoni cpg binding protein 0.0051 0.0056 0.0263
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0047 0.0221
Schistosoma mansoni amine GPCR 0.0142 0.0198 0.0938
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0024 0.0014 0.0014
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0142 0.0198 0.0198
Schistosoma mansoni protein kinase 0.0029 0.0022 0.0105
Brugia malayi ribonucleotide reductase 2 0.0081 0.0104 0.0166
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0002 0.0032
Mycobacterium ulcerans lipase LipD 0.0035 0.0032 0.0644
Onchocerca volvulus 0.0142 0.0198 0.0318
Schistosoma mansoni rab6-interacting 0.0019 0.0007 0.0032
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0022 0.0397
Onchocerca volvulus 0.0048 0.0052 0.0082
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0142 0.0198 0.0938
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0014 0.0304
Loa Loa (eye worm) hypothetical protein 0.0084 0.0107 0.0173
Echinococcus multilocularis muscleblind protein 1 0.0147 0.0206 0.0206
Brugia malayi Importin beta-1 subunit 0.0028 0.0021 0.0033
Leishmania major cytochrome p450-like protein 0.0053 0.0059 0.1103
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.005 0.11
Echinococcus multilocularis G protein coupled receptor 139 0.0142 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0051
Brugia malayi follicle stimulating hormone receptor 0.0142 0.0198 0.0318
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0016 0.0072
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0029 0.0023 0.0023
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0032 0.0802
Brugia malayi AMP-binding enzyme family protein 0.0047 0.005 0.008
Brugia malayi RE15519p 0.0142 0.0198 0.0318
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0142 0.0198 0.0319
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0029 0.0022 0.0035
Echinococcus granulosus tachykinin peptides receptor 99D 0.0142 0.0198 0.0198
Schistosoma mansoni ran 0.0021 0.0009 0.0043
Echinococcus granulosus Protein patched homolog 1 0.0084 0.0107 0.0107
Echinococcus granulosus importin subunit beta 1 0.0028 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0051
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0424 1
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Loa Loa (eye worm) hypothetical protein 0.0213 0.031 0.0498
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Echinococcus granulosus FTZ F1 alpha 0.0452 0.0681 0.0681
Echinococcus multilocularis rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0 0.0001
Onchocerca volvulus 0.0142 0.0198 0.0318
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0016 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0142 0.0198 0.0938
Brugia malayi Tachykinin-like peptides receptor 99D 0.0142 0.0198 0.0318
Leishmania major cathepsin L-like protease 0.0024 0.0014 0.0257
Echinococcus multilocularis tumor protein p63 0.0337 0.0502 0.0502
Schistosoma mansoni hypothetical protein 0.0303 0.0449 0.2129
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0452 0.0681 0.1096
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0076 0.0095 0.2367
Echinococcus granulosus cathepsin L cysteine proteinase 0.0024 0.0014 0.0014
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0093 0.0122 0.0122
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.0424 1
Brugia malayi Cathepsin L-like precursor 0.0024 0.0014 0.0022
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0052
Echinococcus multilocularis survival motor neuron protein 1 0.0502 0.0759 0.0759
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.005 0.1325
Echinococcus multilocularis expressed protein 0.0033 0.0028 0.0028
Echinococcus granulosus rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Toxoplasma gondii cathepsin CPL 0.0024 0.0014 0.0333
Schistosoma mansoni neuropeptide receptor 0.0142 0.0198 0.0938
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0035 0.0032 0.0641
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0074 0.0349
Onchocerca volvulus 0.0142 0.0198 0.0318
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0067 0.1555
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0142 0.0198 0.0938
Brugia malayi hypothetical protein 0.0473 0.0715 0.115
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0016 0.0016
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0016 0.0024
Schistosoma mansoni hypothetical protein 0.0079 0.0099 0.047
Onchocerca volvulus 0.0024 0.0014 0.0022
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0022 0.0403
Plasmodium falciparum ribonucleoside-diphosphate reductase small chain, putative 0.0081 0.0104 0.173
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Schistosoma mansoni hypothetical protein 0.0081 0.0103 0.0485
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0452 0.0681 0.1096
Leishmania major cathepsin L-like protease 0.0024 0.0014 0.0257
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0142 0.0198 0.0319
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0025
Schistosoma mansoni nuclear receptor 0.0126 0.0173 0.0818
Schistosoma mansoni opsin-like receptor 0.0142 0.0198 0.0938
Loa Loa (eye worm) hypothetical protein 0.0047 0.005 0.0081
Plasmodium vivax CDK-related protein kinase 6, putative 0.0396 0.0594 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0142 0.0198 0.0198
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0059 0.0095
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0032 0.052
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0097 0.2255
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0009 0.0009
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0015 0 0.0001
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0021 0.0009 0.0166
Mycobacterium ulcerans ribonucleotide-diphosphate reductase subunit alpha 0.0239 0.0349 0.866
Brugia malayi nuclear receptor NHR-88 0.0126 0.0173 0.0277
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0058 0.0067 0.0108
Brugia malayi Cathepsin L-like precursor 0.0024 0.0014 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0142 0.0198 0.0938
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.004 0.0743
Brugia malayi nuclear receptor RXR 0.0126 0.0173 0.0277
Echinococcus multilocularis ribonucleoside diphosphate reductase large 0.0258 0.0379 0.0379
Schistosoma mansoni hypothetical protein 0.0081 0.0103 0.0485
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0076 0.0095 0.2618
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0045 0.0046 0.0046
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0066 0.0081 0.1504
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0004 0.0006
Loa Loa (eye worm) glutaminase 2 0.0273 0.0402 0.0647
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0035 0.0032 0.0577
Plasmodium falciparum lysine--tRNA ligase 0.0021 0.0009 0.0136
Loa Loa (eye worm) DR-78 0.0126 0.0173 0.0278
Loa Loa (eye worm) transcription factor SMAD2 0.0253 0.0372 0.0599
Schistosoma mansoni glucose transport protein 0.0093 0.0122 0.0577
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0103 0.0138 0.3866
Brugia malayi tailless protein 0.0126 0.0173 0.0277
Echinococcus multilocularis dnaJ subfamily B 0.0683 0.1041 0.1041
Brugia malayi conserved hypotetical protein 0.0126 0.0173 0.0277
Schistosoma mansoni nuclear receptor 0.0126 0.0173 0.0818
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0027 0.0624
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0142 0.0198 0.0198
Brugia malayi Serotonin receptor 0.0142 0.0198 0.0318
Onchocerca volvulus 0.0049 0.0054 0.0086
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0029 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0873 0.1337 0.6347
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0022 0.0488
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0074 0.0349
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0142 0.0198 0.0198
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0029 0.0023 0.0023
Schistosoma mansoni retinoic acid receptor RXR 0.0452 0.0681 0.3231
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0016 0.0002 0.0026
Toxoplasma gondii aldehyde dehydrogenase 0.0066 0.0081 0.2051
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Echinococcus granulosus Smad4 0.0017 0.0004 0.0004
Onchocerca volvulus 0.0126 0.0173 0.0277
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0067 0.125
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0032 0.0802
Brugia malayi Cytochrome P450 family protein 0.0035 0.0032 0.0051
Loa Loa (eye worm) sugar transporter 0.0093 0.0122 0.0196
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Loa Loa (eye worm) CYP4Cod1 0.0053 0.0059 0.0095
Schistosoma mansoni nuclear hormone receptor 0.0452 0.0681 0.3231
Leishmania major hypothetical protein, conserved 0.0035 0.0032 0.0593
Onchocerca volvulus Serine\/threonine kinase homolog 0.0077 0.0097 0.0155
Brugia malayi larval opioid receptor 0.0142 0.0198 0.0318
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Echinococcus granulosus serotonin receptor 0.0142 0.0198 0.0198
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0016 0.0001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0015
Schistosoma mansoni ribonucleoside-diphosphate reductase small chain 0.0081 0.0104 0.049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0424 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0014 0.0242
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0029 0.0022 0.055
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0067 0.0316
Onchocerca volvulus Protein ultraspiracle homolog 0.0452 0.0681 0.1096
Echinococcus granulosus rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0035 0.0032 0.0799
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0033 0.0028 0.0497
Echinococcus granulosus hypothetical protein 0.0142 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0001
Trichomonas vaginalis esterase, putative 0.0035 0.0032 0.0728
Brugia malayi hypothetical protein 0.0326 0.0485 0.078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0014 0.0304
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0452 0.0681 0.1096
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0029 0.0022 0.0022
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0326 0.0485 0.0781
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0042 0.0042 0.0068
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0093 0.0122 0.0122
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0093 0.0122 0.0122
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0058 0.0067 0.125
Echinococcus granulosus mitogen activated protein kinase 3 0.0058 0.0067 0.0067
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0004 0.0004
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain 0.0081 0.0104 0.1928
Trypanosoma cruzi hexose transporter 0.0029 0.0022 0.0403
Plasmodium vivax ribonucleoside-diphosphate reductase large chain, putative 0.0258 0.0379 0.6369
Echinococcus granulosus rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.004 0.0188
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0103 0.0138 0.2576
Schistosoma mansoni myosin xvIII 0.0142 0.0198 0.0938
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0016
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (alpha chain) NrdE (ribonucleotide reductase small subunit) (R1F protein) 0.0239 0.0349 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0142 0.0198 0.0318
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0029 0.0022 0.0022
Onchocerca volvulus 0.0473 0.0715 0.115
Schistosoma mansoni kinase 0.004 0.0039 0.0185
Leishmania major ribonucleoside-diphosphate reductase small chain, putative 0.0081 0.0104 0.194
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0035 0.0032 0.0641
Echinococcus granulosus muscleblind protein 0.0147 0.0206 0.0206
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0014 0.0322
Entamoeba histolytica hypothetical protein 0.0079 0.0099 0.2337
Loa Loa (eye worm) hypothetical protein 0.0147 0.0206 0.0331
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0357 0.0533 1
Echinococcus granulosus glutamate receptor subunit protein glur 0.0029 0.0023 0.0023
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0022 0.0344
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0452 0.0681 0.3231
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0103 0.0138 0.0221
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0016 0.0001 0.0004
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0029 0.0023 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0014 0.0242
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0103 0.0138 0.3223
Schistosoma mansoni biogenic amine (5HT) receptor 0.0142 0.0198 0.0938
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0122 0.2854
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.005 0.0932
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0007 0.0007
Loa Loa (eye worm) ctsf protein 0.0024 0.0014 0.0023
Schistosoma mansoni amine GPCR 0.0142 0.0198 0.0938
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0067 0.1555
Leishmania major cathepsin L-like protease 0.0024 0.0014 0.0257
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0058 0.0067 0.1238
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0021 0.0009 0.0151
Schistosoma mansoni sodium/chloride dependent transporter 0.0146 0.0205 0.0972
Echinococcus granulosus ribonucleoside diphosphate reductase large 0.0258 0.0379 0.0379
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0014 0.0242
Loa Loa (eye worm) hypothetical protein 0.0029 0.0022 0.0036
Echinococcus multilocularis snurportin 1 0.0303 0.0449 0.0449
Brugia malayi cytochrome P450 0.0035 0.0032 0.0051
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0021 0.0374
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Schistosoma mansoni polycystin 1-related 0.0019 0.0007 0.0032
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0016 0.0372
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0032 0.0591
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0452 0.0681 0.3231
Leishmania major hypothetical protein, conserved 0.0034 0.0029 0.0544
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0046 0.0049 0.1244
Echinococcus granulosus lysyl tRNA synthetase 0.0021 0.0009 0.0009
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0126 0.0173 0.0278
Echinococcus granulosus somatostatin receptor 0.0142 0.0198 0.0198
Trypanosoma brucei ribonucleoside-diphosphate reductase large chain 0.0258 0.0379 0.7098
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0142 0.0198 0.0319
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0452 0.0681 0.0681
Brugia malayi glutaminase DH11.1 0.0273 0.0402 0.0646
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0045 0.0046 0.0046
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.005 0.11
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0007 0.0007
Trypanosoma brucei glucose transporter, putative 0.0029 0.0022 0.0389
Brugia malayi sulfakinin receptor protein 0.0142 0.0198 0.0318
Brugia malayi hypothetical protein 0.0142 0.0198 0.0318
Brugia malayi hypothetical protein 0.0025 0.0016 0.0024
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0027 0.0483
Onchocerca volvulus 0.0452 0.0681 0.1096
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0029 0.0702
Chlamydia trachomatis glutamine binding protein 0.0076 0.0095 0.2367
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0035 0.0032 0.0641
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0029 0.0023 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0142 0.0198 0.0938
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0081 0.1871
Leishmania major lanosterol synthase, putative 0.0035 0.0031 0.0573
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0032 0.0672
Echinococcus multilocularis rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0013 0.0272
Echinococcus multilocularis G-protein coupled receptor, putative 0.0142 0.0198 0.0198
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0452 0.0681 0.3231
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.002
Onchocerca volvulus 0.0035 0.0032 0.0051
Brugia malayi nuclear hormone receptor 0.0126 0.0173 0.0277
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0042 0.0042 0.1064
Plasmodium falciparum eukaryotic initiation factor 4A 0.0103 0.0138 0.2301
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Echinococcus granulosus orexin receptor type 2 0.0142 0.0198 0.0198
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0045 0.0046 0.0046
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0079 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Echinococcus granulosus sentrin specific protease 1 0.0046 0.0049 0.0049
Plasmodium falciparum hexose transporter 0.0093 0.0122 0.2038
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (beta chain) NrdB (ribonucleotide reductase small chain) 0.0081 0.0104 0.2883
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0142 0.0198 0.0938
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0035 0.0032 0.0799
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0025 0.0016 0.0016
Echinococcus multilocularis Niemann Pick C1 protein 0.0279 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0081 0.1871
Loa Loa (eye worm) hypothetical protein 0.0103 0.0138 0.0221
Echinococcus granulosus cathepsin l1 0.0024 0.0014 0.0014
Loa Loa (eye worm) Smad1 0.0017 0.0004 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Leishmania major hypothetical protein, conserved 0.0029 0.0022 0.0397
Plasmodium vivax importin-beta 2, putative 0.0028 0.0021 0.0335
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.005 0.117
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0028 0.002 0.0465
Onchocerca volvulus 0.0024 0.0014 0.0022
Onchocerca volvulus 0.0025 0.0016 0.0024
Schistosoma mansoni glutamate receptor AMPA 0.0029 0.0023 0.0106
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0028 0.0045
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0022 0.0344
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0068 0.0082 0.0132
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0014 0.0242
Brugia malayi vesicular acetylcholine transporter unc-17 0.0865 0.1324 0.2132
Schistosoma mansoni biogenic amine (5HT) receptor 0.0142 0.0198 0.0938
Onchocerca volvulus 0.0142 0.0198 0.0318
Onchocerca volvulus 0.0024 0.0014 0.0022
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0032 0.0802
Echinococcus granulosus dro:myosuppressin receptor 0.0142 0.0198 0.0198
Schistosoma mansoni hypothetical protein 0.0068 0.0082 0.0388
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0029 0.0023 0.0023
Brugia malayi nuclear hormone receptor 0.0452 0.0681 0.1096
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Echinococcus multilocularis neuropeptide s receptor 0.0583 0.0885 0.0885
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Brugia malayi hypothetical protein 0.0142 0.0198 0.0318
Leishmania major ribonucleoside-diphosphate reductase large chain, putative 0.0258 0.0379 0.7103
Schistosoma mansoni biogenic amine receptor 0.0142 0.0198 0.0938
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0142 0.0198 0.0938
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0033 0.0028 0.0511
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0027 0.0497
Echinococcus multilocularis neuropeptide FF receptor 2 0.0142 0.0198 0.0198
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0452 0.0681 0.0681
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Echinococcus multilocularis lysyl tRNA synthetase 0.0021 0.0009 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0424 1
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0077 0.0097 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Echinococcus granulosus survival motor neuron protein 1 0.0502 0.0759 0.0759
Brugia malayi hypothetical protein 0.0126 0.0173 0.0277
Brugia malayi Nuclear hormone receptor E75 0.0126 0.0173 0.0277
Echinococcus granulosus Niemann Pick C1 protein 0.0195 0.0281 0.0281
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0016 0.0372
Brugia malayi Nuclear hormone receptor E75 0.0126 0.0173 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0452 0.0681 0.1096
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0022 0.0403
Entamoeba histolytica protein kinase, putative 0.0029 0.0022 0.052
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0103 0.0138 0.0651
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0076 0.0095 0.2227
Giardia lamblia Kinase, CMGC MAPK 0.0058 0.0067 0.1555
Schistosoma mansoni adenoreceptor 0.0142 0.0198 0.0938
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0424 1
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0067 0.1555
Echinococcus granulosus g protein coupled receptor 0.0142 0.0198 0.0198
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0032 0.0802
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0142 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0047 0.005 0.0081
Brugia malayi Melatonin receptor type 1A 0.0142 0.0198 0.0318
Trypanosoma brucei glucose transporter, putative 0.0029 0.0022 0.0389
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0093 0.0122 0.0122
Echinococcus multilocularis allatostatin A receptor 0.0142 0.0198 0.0198
Treponema pallidum sodium- and chloride- dependent transporter 0.0146 0.0205 0.335
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.643 1 1
Brugia malayi G protein-coupled receptor 0.0142 0.0198 0.0318
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0103 0.0138 0.3223
Echinococcus granulosus cathepsin l cysteine peptidase 0.0024 0.0014 0.0014
Trypanosoma cruzi polo-like protein kinase, putative 0.0077 0.0097 0.1807
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0142 0.0198 0.0938
Echinococcus granulosus tumor protein p63 0.0337 0.0502 0.0502
Entamoeba histolytica hypothetical protein 0.0079 0.0099 0.2337
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0326 0.0485 0.0781
Echinococcus granulosus rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.004 0.004 0.0917
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0035 0.0032 0.0591
Echinococcus multilocularis 0.0035 0.0032 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0001 0.0015
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0452 0.0681 0.0681
Chlamydia trachomatis ribonucleoside-diphosphate reductase subunit alpha 0.0258 0.0379 1
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0045 0.0046 0.0046
Onchocerca volvulus 0.0142 0.0198 0.0318
Echinococcus granulosus geminin 0.0873 0.1337 0.1337
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0035 0.0032 0.0641
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0042 0.0042 0.0972
Loa Loa (eye worm) hypothetical protein 0.0452 0.0681 0.1096
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0059 0.1103
Treponema pallidum ribonucleotide-diphosphate reductase subunit alpha 0.0258 0.0379 0.8614
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0007
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0028 0.002 0.002
Brugia malayi hypothetical protein 0.0126 0.0173 0.0277
Schistosoma mansoni ribonucleoside-diphosphate reductase alpha subunit 0.0258 0.0379 0.1796
Brugia malayi Steroid receptor seven-up type 2 0.0452 0.0681 0.1096
Loa Loa (eye worm) hypothetical protein 0.0147 0.0206 0.0331
Onchocerca volvulus 0.0024 0.0014 0.0022
Schistosoma mansoni microtubule-associated protein tau 0.1366 0.2106 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0452 0.0681 0.0681
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0047 0.0076
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0007 0.0099
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0151 0.0212 0.3565
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0059 0.1103
Schistosoma mansoni vesicular acetylcholine transporter 0.0865 0.1324 0.6287
Schistosoma mansoni glutamate receptor NMDA 0.0029 0.0023 0.0106
Schistosoma mansoni opsin-like receptor 0.0142 0.0198 0.0938
Brugia malayi Niemann-Pick C1 protein precursor 0.0195 0.0281 0.0451
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0016 0.0016
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0035 0.0032 0.0641
Loa Loa (eye worm) cysteine protease 0.0024 0.0014 0.0023
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.0329 0.9422
Schistosoma mansoni zinc finger protein 0.0126 0.0173 0.0818
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Schistosoma mansoni nuclear hormone receptor 0.0126 0.0173 0.0818
Mycobacterium leprae RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (ALPHA CHAIN) NRDE (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R1F PROTEIN) 0.0239 0.0349 1
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (beta chain) NrdF1 (ribonucleotide reductase small subunit) (R2F protein) 0.0081 0.0104 0.2883
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0016 0.0001 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0142 0.0198 0.0198
Brugia malayi hypothetical protein 0.0142 0.0198 0.0318
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0035 0.0032 0.0799
Schistosoma mansoni thyroid hormone receptor 0.0452 0.0681 0.3231
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.0449 0.0722
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0074 0.0119
Echinococcus granulosus peptide allatostatin:somatostatin 0.0142 0.0198 0.0198
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0009 0.019
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0033 0.0028 0.0511
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0028 0.002 0.0095
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0028 0.002 0.002
Chlamydia trachomatis ribonucleoside-diphosphate reductase subunit beta 0.0081 0.0104 0.2612
Brugia malayi MH1 domain containing protein 0.0017 0.0004 0.0005
Echinococcus granulosus biogenic amine 5HT receptor 0.0142 0.0198 0.0198
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0029 0.0022 0.0359
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0142 0.0198 0.0938
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0093 0.0122 0.0122
Echinococcus multilocularis nuclear receptor nhr 48 0.0126 0.0173 0.0173
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0452 0.0681 0.0681
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0452 0.0681 0.1096
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0142 0.0198 0.0938
Onchocerca volvulus 0.0019 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0052
Plasmodium falciparum ribonucleoside-diphosphate reductase small chain, putative 0.0028 0.002 0.0315
Loa Loa (eye worm) hypothetical protein 0.0452 0.0681 0.1096
Brugia malayi AMP-binding enzyme family protein 0.0047 0.005 0.008
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.004 0.004
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0142 0.0198 0.0938
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0452 0.0681 0.0681
Echinococcus granulosus rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Brugia malayi Dopamine receptor protein 2 0.0142 0.0198 0.0318
Schistosoma mansoni lipoxygenase 0.0081 0.0103 0.0488
Plasmodium vivax sentrin-specific protease 1, putative 0.0046 0.0049 0.0812
Brugia malayi ORL1-like opioid receptor 0.0142 0.0198 0.0318
Echinococcus multilocularis neuropeptide receptor 0.0142 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Treponema pallidum ribonucleotide-diphosphate reductase subunit beta 0.0081 0.0104 0.0276
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0032 0.0593
Brugia malayi Augmenter of liver regeneration 0.0034 0.0029 0.0047
Loa Loa (eye worm) hypothetical protein 0.0028 0.0021 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0014 0.0242
Plasmodium falciparum ribonucleoside-diphosphate reductase large subunit, putative 0.0258 0.0379 0.6369
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0025 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0452 0.0681 0.1096
Echinococcus granulosus GPCR family 2 0.0068 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Trypanosoma brucei THT1 - hexose transporter, putative 0.0029 0.0022 0.0389
Onchocerca volvulus 0.0025 0.0016 0.0024
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Echinococcus granulosus biogenic amine 5HT receptor 0.0142 0.0198 0.0198
Brugia malayi MH2 domain containing protein 0.0017 0.0004 0.0005
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0142 0.0198 0.0938
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0424 1
Trypanosoma brucei polo-like protein kinase 0.0077 0.0097 0.1794
Schistosoma mansoni transcription factor LCR-F1 0.0079 0.0099 0.047
Schistosoma mansoni protein kinase 0.0029 0.0022 0.0105
Echinococcus granulosus vesicular acetylcholine transporter 0.0865 0.1324 0.1324
Onchocerca volvulus 0.0142 0.0198 0.0318
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0016 0.0001 0.0001
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0142 0.0198 0.0938
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0029 0.0029
Schistosoma mansoni sodium/chloride dependent transporter 0.0025 0.0016 0.0072
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0016 0.0025
Brugia malayi hypothetical protein 0.0079 0.0099 0.0159
Echinococcus multilocularis General substrate transporter 0.008 0.0102 0.0102
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0029 0.0022 0.055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0014 0.0304
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0142 0.0198 0.0938
Schistosoma mansoni hypothetical protein 0.0142 0.0198 0.0938
Trypanosoma cruzi cysteine peptidase, putative 0.0024 0.0014 0.0257
Trichomonas vaginalis ran, putative 0.0021 0.0009 0.0194
Echinococcus granulosus smad 0.0017 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0452 0.0681 0.1096
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0016 0.0001 0.0004
Loa Loa (eye worm) serotonin transporter b 0.0146 0.0205 0.033
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0016 0.0001 0.0019
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0032 0.0591
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0102 0.0135 0.0641
Brugia malayi hypothetical protein 0.0019 0.0007 0.0011
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0079 0.0099 0.0099
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0035 0.0032 0.0799
Loa Loa (eye worm) cytochrome P450 family protein 0.0111 0.0151 0.0242
Echinococcus granulosus eukaryotic initiation factor 4A 0.0103 0.0138 0.0138
Echinococcus granulosus expressed conserved protein 0.0183 0.0262 0.0262
Schistosoma mansoni Smad4 0.0017 0.0004 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0024 0.0014 0.0304
Onchocerca volvulus 0.0146 0.0205 0.0329
Trypanosoma cruzi protein farnesyltransferase, putative 0.0042 0.0042 0.0787
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Echinococcus multilocularis protein patched 0.0084 0.0107 0.0107
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0074 0.0349
Brugia malayi TAR-binding protein 0.0062 0.0074 0.0118
Echinococcus granulosus alpha 1A adrenergic receptor 0.0142 0.0198 0.0198
Onchocerca volvulus 0.0142 0.0198 0.0318
Giardia lamblia Prolyl-tRNA synthetase 0.0028 0.002 0.0454
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0025
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0326 0.0485 0.0485
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0014
Schistosoma mansoni protein kinase 0.0029 0.0022 0.0105
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0035 0.0032 0.0641
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0033
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0029 0.053
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.005 0.1325
Mycobacterium ulcerans hypothetical protein 0.0035 0.0032 0.0644
Plasmodium vivax RNA helicase-1, putative 0.0103 0.0138 0.2301
Schistosoma mansoni hypothetical protein 0.0068 0.0082 0.0388
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.004 0.004
Schistosoma mansoni glucose transport protein 0.0093 0.0122 0.0577
Loa Loa (eye worm) hypothetical protein 0.0146 0.0204 0.0329
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0126 0.0173 0.0173
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0452 0.0681 0.0681
Schistosoma mansoni glutamate receptor kainate 0.0029 0.0023 0.0106
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0142 0.0198 0.0198
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0035 0.0032 0.0641
Schistosoma mansoni hypothetical protein 0.0142 0.0198 0.0938
Onchocerca volvulus 0.0047 0.005 0.008
Echinococcus granulosus neuropeptides capa receptor 0.0142 0.0198 0.0198
Onchocerca volvulus 0.0035 0.0032 0.0051
Mycobacterium tuberculosis Conserved protein 0.0035 0.0032 0.0802
Loa Loa (eye worm) hypothetical protein 0.0326 0.0485 0.0781
Loa Loa (eye worm) fibroinase 0.0024 0.0014 0.0023
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0103 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Trypanosoma brucei glucose transporter, putative 0.0029 0.0022 0.0389
Schistosoma mansoni sodium-dependent amino acid transporter 0.0025 0.0016 0.0072
Brugia malayi nuclear receptor NHR-88 0.0452 0.0681 0.1096
Brugia malayi G protein-coupled receptor F59B2.13 0.0142 0.0198 0.0318
Echinococcus multilocularis NMDA receptor 0.0029 0.0023 0.0023
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0046 0.0049 0.0232
Brugia malayi nuclear hormone receptor family member nhr-6 0.0126 0.0173 0.0277
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0014 0.0242
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0029 0.0022 0.0022
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0103 0.0138 0.0138
Schistosoma mansoni amine GPCR 0.0142 0.0198 0.0938
Trypanosoma brucei protein kinase, putative 0.0058 0.0067 0.1238
Trypanosoma brucei glucose transporter, putative 0.0029 0.0022 0.0389
Plasmodium vivax ribonucleotide reductase small subunit, putative 0.0028 0.002 0.0315
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0042 0.0042 0.0989
Brugia malayi hypothetical protein 0.0142 0.0198 0.0318
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0035 0.0032 0.0799
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0014 0.0304
Loa Loa (eye worm) hypothetical protein 0.004 0.004 0.0064
Entamoeba histolytica hypothetical protein 0.0079 0.0099 0.2337
Trichomonas vaginalis CAMK family protein kinase 0.0077 0.0097 0.2255
Schistosoma mansoni amine GPCR 0.0142 0.0198 0.0938
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0142 0.0198 0.0198
Brugia malayi CXXC zinc finger family protein 0.0048 0.0052 0.0082
Echinococcus granulosus 7tm_1 domain containing protein 0.0142 0.0198 0.0198
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0142 0.0198 0.0319
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0027 0.0663
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0059 0.0095
Wolbachia endosymbiont of Brugia malayi ribonucleotide-diphosphate reductase subunit alpha 0.0239 0.0349 1
Brugia malayi Smad1 0.0017 0.0004 0.0005
Trypanosoma cruzi polo-like protein kinase, putative 0.0077 0.0097 0.1807
Onchocerca volvulus 0.0024 0.0014 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0452 0.0681 0.1096
Echinococcus multilocularis fmrfamide receptor 0.0142 0.0198 0.0198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0014
Toxoplasma gondii ribonucleoside-diphosphate reductase large chain 0.0258 0.0379 0.9759
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0022 0.0105
Echinococcus multilocularis rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Schistosoma mansoni hypothetical protein 0.0029 0.0023 0.0106
Toxoplasma gondii ABC1 family protein 0.0035 0.0032 0.0796
Leishmania major C-8 sterol isomerase-like protein 0.0357 0.0533 1
Brugia malayi Latrophilin receptor protein 2 0.0068 0.0082 0.0132
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0042 0.0042 0.0972
Echinococcus multilocularis rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Brugia malayi Cathepsin L-like cysteine proteinase 0.0016 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0035 0.0032 0.0799
Entamoeba histolytica cysteine protease, putative 0.0024 0.0014 0.0322
Loa Loa (eye worm) hypothetical protein 0.0146 0.0205 0.033
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0865 0.1324 0.2132
Trichomonas vaginalis glutaminase, putative 0.0273 0.0402 0.9471
Echinococcus multilocularis cathepsin L cysteine protease 0.0024 0.0014 0.0014
Onchocerca volvulus 0.0142 0.0198 0.0318
Brugia malayi Cytochrome P450 family protein 0.0053 0.0059 0.0095
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0035 0.0032 0.0641
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0028 0.0635
Loa Loa (eye worm) hypothetical protein 0.0146 0.0205 0.033
Echinococcus granulosus RUN 0.0019 0.0007 0.0007
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0013 0.0272
Giardia lamblia Kinase, PLK 0.0077 0.0097 0.2255
Brugia malayi Muscleblind-like protein 0.0147 0.0206 0.033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0142 0.0198 0.0938
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0142 0.0198 0.0938
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0022 0.0488
Schistosoma mansoni hypothetical protein 0.0068 0.0082 0.0388
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.005 0.11
Echinococcus granulosus glutamate receptor 2 0.0045 0.0046 0.0046
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0032 0.0728
Echinococcus multilocularis protein dispatched 1 0.0095 0.0126 0.0126
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.004 0.073
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0103 0.0138 0.0138
Schistosoma mansoni hypothetical protein 0.0873 0.1337 0.6347
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0046 0.0049 0.1287
Echinococcus multilocularis fmrfamide receptor 0.0142 0.0198 0.0198
Chlamydia trachomatis lysine--tRNA ligase 0.0021 0.0009 0.0073
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0016
Echinococcus multilocularis orexin receptor type 2 0.0142 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0126 0.0173 0.0278
Loa Loa (eye worm) hypothetical protein 0.0452 0.0681 0.1096
Schistosoma mansoni neuropeptide receptor 0.0142 0.0198 0.0938
Echinococcus granulosus snurportin 1 0.0303 0.0449 0.0449
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0028 0.002 0.0095
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0213 0.031 0.0498
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0009 0.0138
Brugia malayi lysyl-tRNA synthetase 0.0021 0.0009 0.0014
Brugia malayi beta-lactamase family protein 0.0035 0.0032 0.0051
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0142 0.0198 0.0318
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0051
Toxoplasma gondii histone lysine methyltransferase SET1 0.0091 0.0118 0.3033
Brugia malayi Sugar transporter family protein 0.0093 0.0122 0.0196
Trypanosoma brucei C-8 sterol isomerase, putative 0.0357 0.0533 1
Brugia malayi G-protein coupled receptor 0.0142 0.0198 0.0318
Schistosoma mansoni hypothetical protein 0.0081 0.0103 0.0485
Loa Loa (eye worm) hypothetical protein 0.0049 0.0054 0.0087
Loa Loa (eye worm) hypothetical protein 0.0452 0.0681 0.1096
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0142 0.0198 0.0938
Echinococcus multilocularis g protein coupled receptor 0.0142 0.0198 0.0198
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0032 0.0512
Schistosoma mansoni hypothetical protein 0.0093 0.0122 0.0577
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0016 0.0001 0.0015
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0016 0.0016
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.004 0.0743
Loa Loa (eye worm) steroid hormone receptor 0.0452 0.0681 0.1096
Leishmania major importin beta-1 subunit, putative 0.0023 0.0013 0.0231
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0022 0.0488
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Mycobacterium ulcerans beta-lactamase 0.0035 0.0032 0.0644
Echinococcus multilocularis mitogen activated protein kinase 3 0.0058 0.0067 0.0067
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0142 0.0198 0.0198
Trypanosoma brucei ribonucleoside-diphosphate reductase small chain 0.0081 0.0104 0.1928
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0116 0.0157 0.0157
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0016 0.0024
Brugia malayi ecdysteroid receptor 0.4 0.6212 1
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0025 0.0016 0.0244
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0047 0.0047
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0146 0.0205 0.0972
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0029 0.0729
Onchocerca volvulus 0.0126 0.0173 0.0277
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0074 0.0118
Loa Loa (eye worm) hypothetical protein 0.0326 0.0485 0.0781
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0024 0.0014 0.0014
Echinococcus multilocularis neuropeptide Y receptor 0.0142 0.0198 0.0198
Schistosoma mansoni histamine h1 receptor 0.0142 0.0198 0.0938
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0029 0.0544
Echinococcus granulosus ecdysone induced protein 78C 0.0452 0.0681 0.0681
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0126 0.0173 0.0173
Trichomonas vaginalis rotamase, putative 0.0033 0.0028 0.0635
Entamoeba histolytica Ran family GTPase 0.0021 0.0009 0.0212
Trypanosoma brucei cytochrome P450, putative 0.0053 0.0059 0.109
Loa Loa (eye worm) hypothetical protein 0.0142 0.0198 0.0319
Schistosoma mansoni loxhd1 0.0019 0.0007 0.0032
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0103 0.0138 0.3223
Loa Loa (eye worm) hypothetical protein 0.0047 0.005 0.0081
Echinococcus granulosus g protein coupled receptor 0.0142 0.0198 0.0198
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0009 0.0169
Echinococcus multilocularis rhodopsin orphan GPCR 0.0142 0.0198 0.0198
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0142 0.0198 0.0318
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0029 0.0023 0.0023

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 11 uM Inhibition of Herpes simplex virus type 1 ribonucleotide reductase ChEMBL. 8411018

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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