Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | esterase/lipase LipP | 0.0107 | 0.0355 | 0.2731 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0162 | 0.0578 | 0.0755 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0046 | 0.0109 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0123 | 0.0418 | 0.3245 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0066 | 0.0062 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0123 | 0.0418 | 0.0414 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0057 | 0.0155 | 0.0206 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0069 | 0.0094 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.025 | 0.0931 | 0.1237 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.0242 | 0.0331 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0046 | 0.0109 | 0.0442 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.1174 | 0.1599 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0123 | 0.0418 | 0.3245 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0057 | 0.0155 | 0.0212 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0079 | 0.0242 | 0.0294 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0046 | 0.0109 | 0.2095 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0046 | 0.0109 | 0.0746 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.031 | 0.1174 | 0.1599 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0112 | 0.0376 | 0.8155 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0107 | 0.0355 | 0.1272 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0072 | 0.1269 |
Loa Loa (eye worm) | hypothetical protein | 0.1835 | 0.7324 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0132 | 0.0457 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0355 | 0.0479 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0046 | 0.0109 | 0.2095 |
Brugia malayi | Carboxylesterase family protein | 0.031 | 0.1174 | 0.1571 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0107 | 0.0355 | 0.2493 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0187 | 0.0679 | 0.0675 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0085 | 0.0111 |
Echinococcus granulosus | zinc finger protein | 0.0027 | 0.0034 | 0.0042 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0171 | 0.0612 | 0.0801 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0045 | 0.0104 | 0.01 |
Schistosoma mansoni | cpg binding protein | 0.0154 | 0.0546 | 0.0746 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0187 | 0.0679 | 0.0927 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0249 | 0.0927 | 0.1261 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0046 | 0.0109 | 0.1883 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0046 | 0.0109 | 0.1883 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0046 | 0.0109 | 0.1883 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0069 | 0.0961 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0676 | 0.2651 | 0.2649 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0046 | 0.0109 | 0.2095 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0107 | 0.0355 | 0.1272 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0682 | 0.2676 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0302 | 0.114 | 0.4227 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.0057 | 0.7958 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0046 | 0.0109 | 0.0347 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0355 | 0.0479 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0072 | 0.0093 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0302 | 0.114 | 0.4227 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0033 | 0.0057 | 0.0935 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0302 | 0.114 | 0.4227 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.0072 | 0.0452 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0187 | 0.0679 | 0.0922 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.031 | 0.1174 | 0.1603 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0046 | 0.0109 | 0.2095 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0276 | 0.1035 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.031 | 0.1174 | 0.1171 |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.0109 | 0.2377 |
Brugia malayi | PHD-finger family protein | 0.0033 | 0.0055 | 0.0038 |
Echinococcus multilocularis | zinc finger protein | 0.0027 | 0.0034 | 0.003 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0162 | 0.0578 | 0.0785 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0028 | 0.0608 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0069 | 0.1198 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0355 | 0.0479 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0107 | 0.0355 | 0.0484 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0107 | 0.0355 | 0.7611 |
Loa Loa (eye worm) | carboxylesterase | 0.1835 | 0.7324 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0132 | 0.0457 | 0.0588 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.0242 | 0.0331 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.031 | 0.1174 | 0.1603 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0045 | 0.0104 | 0.0136 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.0072 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0069 | 0.1198 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0123 | 0.0418 | 0.3245 |
Brugia malayi | glutaminase DH11.1 | 0.033 | 0.1255 | 0.1682 |
Brugia malayi | Inositol-1 | 0.0037 | 0.0072 | 0.0061 |
Toxoplasma gondii | ABC1 family protein | 0.0107 | 0.0355 | 0.3321 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0132 | 0.0457 | 0.0619 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0107 | 0.0355 | 0.0351 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0069 | 0.9565 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.0057 | 0.0321 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0069 | 0.0065 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0069 | 0.0112 |
Brugia malayi | Carboxylesterase family protein | 0.031 | 0.1174 | 0.1571 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.0057 | 0.0016 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0133 | 0.0459 | 0.0455 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0046 | 0.0109 | 0.0111 |
Onchocerca volvulus | 0.0107 | 0.0355 | 0.1958 | |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0072 | 0.0139 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0123 | 0.0418 | 0.3946 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0046 | 0.0109 | 0.0746 |
Brugia malayi | follicle stimulating hormone receptor | 0.0231 | 0.0854 | 0.1133 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0302 | 0.114 | 0.8922 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0187 | 0.0679 | 0.0927 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0005 | 0.0007 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0046 | 0.0109 | 0.0105 |
Mycobacterium tuberculosis | Probable reductase | 0.0302 | 0.114 | 0.4227 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0021 | 0.0007 | 0.001 |
Echinococcus granulosus | carboxylesterase 5A | 0.1835 | 0.7324 | 1 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0046 | 0.0109 | 0.0111 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0072 | 0.0068 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0112 | 0.0376 | 0.8105 |
Mycobacterium leprae | Probable lipase LipE | 0.0107 | 0.0355 | 0.2685 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.031 | 0.1174 | 0.1171 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 0.0171 | 0.0229 |
Echinococcus granulosus | cpg binding protein | 0.0154 | 0.0546 | 0.0741 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0676 | 0.2651 | 0.362 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0069 | 0.0089 |
Toxoplasma gondii | thioredoxin reductase | 0.0132 | 0.0457 | 0.4328 |
Loa Loa (eye worm) | beta-lactamase | 0.0107 | 0.0355 | 0.0479 |
Brugia malayi | Carboxylesterase family protein | 0.1835 | 0.7324 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0046 | 0.0109 | 0.1883 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0069 | 0.0057 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1835 | 0.7324 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0107 | 0.0355 | 0.7673 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0107 | 0.0355 | 0.1272 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0034 | 0.006 | 0.0044 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0079 | 0.0242 | 0.0326 |
Onchocerca volvulus | 0.031 | 0.1174 | 1 | |
Loa Loa (eye worm) | glutaminase 2 | 0.033 | 0.1255 | 0.1709 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0123 | 0.0418 | 0.0571 |
Echinococcus granulosus | geminin | 0.0519 | 0.2017 | 0.275 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0107 | 0.0355 | 0.1272 |
Onchocerca volvulus | 0.0082 | 0.0252 | 0.0957 | |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0302 | 0.114 | 0.4227 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0046 | 0.0109 | 0.0143 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0162 | 0.0578 | 0.0785 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0112 | 0.0376 | 0.0513 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0057 | 0.0691 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0171 | 0.0234 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0034 | 0.0061 | 0.0045 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0057 | 0.0155 | 0.0174 |
Schistosoma mansoni | hypothetical protein | 0.0519 | 0.2017 | 0.2754 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.031 | 0.1174 | 0.9327 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0046 | 0.0109 | 0.2095 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0016 | 0.0356 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0069 | 0.0112 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0069 | 0.9565 |
Onchocerca volvulus | 0.031 | 0.1174 | 1 | |
Plasmodium falciparum | glutathione reductase | 0.0132 | 0.0457 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.1649 | 0.6573 | 0.8974 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.01 | 0.0132 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1835 | 0.7324 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.1649 | 0.6573 | 0.6571 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0046 | 0.0109 | 0.0442 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1835 | 0.7324 | 0.7323 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.025 | 0.0931 | 0.1237 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0335 | 0.1276 | 0.4737 |
Loa Loa (eye worm) | hypothetical protein | 0.1835 | 0.7324 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.025 | 0.0931 | 0.1266 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0171 | 0.0234 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.0004 | 0.0005 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0066 | 0.0085 |
Echinococcus granulosus | acetylcholinesterase | 0.1835 | 0.7324 | 1 |
Brugia malayi | hypothetical protein | 0.031 | 0.1174 | 0.1571 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0036 | 0.0068 | 0.0093 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.0487 | 0.0665 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.031 | 0.1174 | 0.1603 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0069 | 0.0112 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0067 | 0.0193 | 0.0189 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0306 | 0.1157 | 0.158 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0107 | 0.0355 | 0.2493 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0107 | 0.0355 | 0.1272 |
Brugia malayi | Carboxylesterase family protein | 0.031 | 0.1174 | 0.1571 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0082 | 0.0252 | 0.0345 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.0242 | 0.0331 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0057 | 0.0155 | 0.1362 |
Echinococcus multilocularis | acetylcholinesterase | 0.1835 | 0.7324 | 0.7323 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.003 | 0.0046 | 0.0063 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0072 | 0.1034 |
Schistosoma mansoni | rotamase | 0.0034 | 0.0061 | 0.0083 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0072 | 0.1269 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.0109 | 0.2377 |
Echinococcus granulosus | GPCR family 2 | 0.0079 | 0.0242 | 0.0326 |
Loa Loa (eye worm) | glutaminase | 0.033 | 0.1255 | 0.1709 |
Schistosoma mansoni | cpg binding protein | 0.0144 | 0.0505 | 0.069 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.1174 | 0.1599 |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 0.0171 | 0.0229 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.031 | 0.1174 | 0.1603 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.025 | 0.0931 | 0.1266 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0072 | 0.0099 |
Mycobacterium tuberculosis | Conserved protein | 0.0107 | 0.0355 | 0.1272 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0046 | 0.0109 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.031 | 0.1174 | 0.1603 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0072 | 0.0093 |
Brugia malayi | TAR-binding protein | 0.0061 | 0.0171 | 0.0197 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0069 | 0.0112 |
Loa Loa (eye worm) | carboxylesterase | 0.031 | 0.1174 | 0.1599 |
Echinococcus multilocularis | cpg binding protein | 0.0154 | 0.0546 | 0.0542 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0249 | 0.0927 | 0.1261 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0072 | 0.1034 |
Mycobacterium ulcerans | glutaminase | 0.033 | 0.1255 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0076 | 0.0098 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0036 | 0.0068 | 0.0064 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.0242 | 0.0331 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0126 | 0.0166 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0107 | 0.0355 | 0.1272 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0187 | 0.0679 | 0.0922 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0072 | 0.0139 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0075 | 0.0065 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0028 | 0.0262 |
Onchocerca volvulus | 0.031 | 0.1174 | 1 | |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0046 | 0.0109 | 0.0907 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0107 | 0.0355 | 0.0484 |
Brugia malayi | Bromodomain containing protein | 0.0082 | 0.0253 | 0.0309 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0107 | 0.0355 | 0.7611 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0355 | 0.0479 |
Onchocerca volvulus | 0.0144 | 0.0505 | 0.3438 | |
Mycobacterium ulcerans | hypothetical protein | 0.0107 | 0.0355 | 0.2731 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0079 | 0.0242 | 0.0326 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0061 | 0.0042 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0079 | 0.0242 | 0.0238 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0123 | 0.0418 | 0.0571 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.0612 | 0.0836 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0107 | 0.0355 | 0.0479 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0057 | 0.0155 | 0.0151 |
Brugia malayi | CXXC zinc finger family protein | 0.0144 | 0.0505 | 0.0655 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0069 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0242 | 0.0326 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0187 | 0.0679 | 0.0922 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.031 | 0.1174 | 0.1171 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.031 | 0.1174 | 0.4354 |
Mycobacterium ulcerans | lipase LipD | 0.0107 | 0.0355 | 0.2731 |
Brugia malayi | beta-lactamase | 0.0107 | 0.0355 | 0.0448 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0132 | 0.0457 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.031 | 0.1174 | 0.4354 |
Echinococcus multilocularis | acetylcholinesterase | 0.1835 | 0.7324 | 0.7323 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0171 | 0.0234 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.031 | 0.1174 | 0.9348 |
Plasmodium vivax | glutathione reductase, putative | 0.0132 | 0.0457 | 1 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0112 | 0.0376 | 0.0372 |
Echinococcus granulosus | BC026374 protein S09 family | 0.031 | 0.1174 | 0.1599 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0079 | 0.0242 | 0.0326 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0069 | 0.0112 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0046 | 0.0109 | 0.2095 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.0109 | 0.1883 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0132 | 0.0457 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0069 | 0.0961 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0335 | 0.1276 | 0.4737 |
Brugia malayi | hypothetical protein | 0.0044 | 0.01 | 0.01 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.031 | 0.1174 | 0.9327 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.0612 | 0.0831 |
Echinococcus granulosus | expressed protein | 0.0034 | 0.0061 | 0.0078 |
Brugia malayi | beta-lactamase family protein | 0.0107 | 0.0355 | 0.0448 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0069 | 0.0112 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0036 | 0.0068 | 0.0088 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0082 | 0.0252 | 0.034 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0046 | 0.0109 | 0.1883 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0107 | 0.0355 | 0.2731 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 0.0171 | 0.0229 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0187 | 0.0679 | 0.0675 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0162 | 0.0578 | 0.0575 |
Onchocerca volvulus | 0.031 | 0.1174 | 1 | |
Trichomonas vaginalis | esterase, putative | 0.0107 | 0.0355 | 0.2493 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.1174 | 0.1599 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0016 | 0.2253 |
Treponema pallidum | NADH oxidase | 0.0046 | 0.0109 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.007 | 0.0207 | 0.0283 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 0.0171 | 0.0197 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0123 | 0.0418 | 0.9117 |
Schistosoma mansoni | glutaminase | 0.033 | 0.1255 | 0.1713 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0079 | 0.0242 | 0.0238 |
Schistosoma mansoni | zinc finger protein | 0.0027 | 0.0034 | 0.0047 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0036 | 0.0068 | 0.0088 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0028 | 0.0262 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.0072 | 0.6056 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0112 | 0.0376 | 0.0477 |
Echinococcus multilocularis | geminin | 0.0519 | 0.2017 | 0.2014 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0072 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0028 | 0.0033 |
Echinococcus multilocularis | neuroligin | 0.031 | 0.1174 | 0.1171 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.1174 | 0.1599 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0069 | 0.0112 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 0.0171 | 0.0229 |
Mycobacterium tuberculosis | Conserved protein | 0.0107 | 0.0355 | 0.1272 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0335 | 0.1276 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0187 | 0.0679 | 0.0927 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.0004 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.1649 | 0.6573 | 0.8974 |
Brugia malayi | beta-lactamase family protein | 0.0107 | 0.0355 | 0.0448 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0033 | 0.0057 | 0.0935 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0082 | 0.0252 | 0.0308 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0046 | 0.0109 | 0.0907 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0171 | 0.0234 |
Leishmania major | trypanothione reductase | 0.0132 | 0.0457 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0249 | 0.0927 | 0.1232 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0107 | 0.0355 | 0.7673 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0123 | 0.0418 | 0.0566 |
Schistosoma mansoni | alpha-glucosidase | 0.014 | 0.0487 | 0.0665 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.031 | 0.1174 | 0.4354 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0005 | 0.0002 |
Trichomonas vaginalis | rotamase, putative | 0.0034 | 0.0061 | 0.0042 |
Echinococcus multilocularis | expressed protein | 0.0034 | 0.0061 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0355 | 0.0479 |
Onchocerca volvulus | 0.0107 | 0.0355 | 0.1958 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.031 | 0.1174 | 0.1603 |
Loa Loa (eye worm) | histone methyltransferase | 0.0045 | 0.0104 | 0.0136 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0171 | 0.0234 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0046 | 0.0109 | 0.2095 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.003 | 0.0046 | 0.0042 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0046 | 0.0109 | 0.0746 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0079 | 0.0242 | 0.0294 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0072 | 0.0099 |
Onchocerca volvulus | 0.031 | 0.1174 | 1 | |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0046 | 0.0109 | 0.0148 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0187 | 0.0679 | 0.0892 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0046 | 0.0109 | 0.2095 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0034 | 0.006 | 0.0044 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0028 | 0.0262 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0162 | 0.0578 | 0.0575 |
Brugia malayi | glutathione reductase | 0.0132 | 0.0457 | 0.0588 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0107 | 0.0355 | 0.1272 |
Echinococcus granulosus | acetylcholinesterase | 0.1835 | 0.7324 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.1835 | 0.7324 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0199 | 0.0267 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.0057 | 0.0152 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0069 | 0.0112 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0036 | 0.0068 | 0.0064 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0107 | 0.0355 | 0.2493 |
Onchocerca volvulus | 0.0094 | 0.0302 | 0.1446 | |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0072 | 0.0549 |
Echinococcus multilocularis | GPCR, family 2 | 0.0079 | 0.0242 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0252 | 0.034 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0107 | 0.0355 | 0.0448 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0057 | 0.0691 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0082 | 0.0252 | 0.0249 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.003 | 0.0046 | 0.0058 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0069 | 0.0518 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0046 | 0.0109 | 0.2095 |
Schistosoma mansoni | hypothetical protein | 0.0519 | 0.2017 | 0.2754 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0112 | 0.0376 | 0.8155 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0123 | 0.0418 | 0.1511 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0046 | 0.0109 | 0.1883 |
Schistosoma mansoni | cpg binding protein | 0.0154 | 0.0546 | 0.0746 |
Echinococcus granulosus | neuroligin | 0.031 | 0.1174 | 0.1599 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0046 | 0.0109 | 0.1883 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0046 | 0.0109 | 0.2377 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0132 | 0.0457 | 0.1658 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0133 | 0.0459 | 0.0622 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0033 | 0.0057 | 0.0404 |
Plasmodium vivax | hypothetical protein, conserved | 0.0107 | 0.0355 | 0.7673 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0203 | 0.0272 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0057 | 0.0155 | 0.0206 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0112 | 0.0376 | 0.8155 |
Trypanosoma brucei | trypanothione reductase | 0.0132 | 0.0457 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0144 | 0.0505 | 0.0685 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0112 | 0.0376 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.1174 | 0.1599 |
Trichomonas vaginalis | glutaminase, putative | 0.033 | 0.1255 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0046 | 0.0109 | 0.2095 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0046 | 0.0109 | 0.2377 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0046 | 0.0109 | 0.1883 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.1174 | 0.1599 |
Loa Loa (eye worm) | carboxylesterase | 0.031 | 0.1174 | 0.1599 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0046 | 0.0109 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0028 | 0.0608 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0069 | 0.0089 |
Schistosoma mansoni | gliotactin | 0.031 | 0.1174 | 0.1603 |
Mycobacterium tuberculosis | Conserved protein | 0.0107 | 0.0355 | 0.1272 |
Loa Loa (eye worm) | glutathione reductase | 0.0132 | 0.0457 | 0.0619 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0231 | 0.0854 | 0.1162 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0112 | 0.0376 | 0.8105 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0107 | 0.0355 | 0.0479 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0067 | 0.0193 | 0.0258 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0046 | 0.0109 | 1 |
Brugia malayi | RNA binding protein | 0.0061 | 0.0171 | 0.0197 |
Mycobacterium leprae | conserved hypothetical protein | 0.0107 | 0.0355 | 0.2685 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0107 | 0.0355 | 0.2493 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0028 | 0.0113 |
Brugia malayi | Carboxylesterase family protein | 0.031 | 0.1174 | 0.1571 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0302 | 0.114 | 0.4227 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0676 | 0.2651 | 0.3617 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.1174 | 0.1599 |
Mycobacterium ulcerans | beta-lactamase | 0.0107 | 0.0355 | 0.2731 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.031 | 0.1174 | 0.1599 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0107 | 0.0355 | 0.2493 |
Onchocerca volvulus | 0.0107 | 0.0355 | 0.1958 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 0.0171 | 0.0167 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0034 | 0.0061 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0355 | 0.0479 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0335 | 0.1276 | 0.4737 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 35.4813 uM | PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.