Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 1 | 1 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0816 | 0.0816 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.726 | 0.5 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0816 | 0.0816 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.4732 | 0.4732 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0678 | 0.0678 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.726 | 0.5 |
Schistosoma mansoni | lamin | 0.0028 | 0.4732 | 0.4732 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.726 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 1 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.4732 | 0.4732 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.726 | 0.5 |
Schistosoma mansoni | lamin | 0.0028 | 0.4732 | 0.4732 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.726 | 0.726 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.4732 | 0.4732 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.726 | 0.726 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0816 | 0.0816 |
Echinococcus multilocularis | lamin | 0.0028 | 0.4732 | 0.4732 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.1218 | 0.1218 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0678 | 0.0678 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.4732 | 0.4732 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.726 | 0.726 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.726 | 0.726 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.4732 | 0.4732 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.4732 | 0.4732 |
Onchocerca volvulus | 0.0028 | 0.4732 | 1 | |
Echinococcus multilocularis | musashi | 0.0028 | 0.4732 | 0.4732 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.1218 | 0.1218 |
Onchocerca volvulus | 0.0028 | 0.4732 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.4732 | 0.4732 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.4732 | 0.4732 |
Echinococcus granulosus | lamin | 0.0028 | 0.4732 | 0.4732 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.4732 | 0.4732 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.4593 | 0.4593 |
Brugia malayi | hypothetical protein | 0.0037 | 0.726 | 0.726 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.