Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | adenosylhomocysteinase | 0.0578 | 0.6106 | 0.6106 |
Echinococcus granulosus | kelch ECH associated protein 1 like | 0.0092 | 0.0796 | 0.0796 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0031 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.306 | 0.306 |
Mycobacterium ulcerans | adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 0.0162 | 0.1558 | 0.1527 |
Loa Loa (eye worm) | hypothetical protein | 0.0247 | 0.2482 | 0.2482 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0046 | 0.0293 | 0.0293 |
Brugia malayi | MH2 domain containing protein | 0.0028 | 0.0091 | 0.0091 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0247 | 0.2482 | 0.2482 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0023 | 0.0033 | 0.0033 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.012 | 0.012 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0333 | 0.3428 | 0.3428 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0228 | 0.2275 | 0.2275 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0333 | 0.3428 | 0.3428 |
Schistosoma mansoni | smad1 5 8 and | 0.0063 | 0.047 | 0.047 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.0467 | 0.0467 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0031 | 0.012 | 0.012 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.012 | 0.012 |
Loa Loa (eye worm) | nuclear factor I | 0.0035 | 0.0164 | 0.0164 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.0934 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.012 | 0.012 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0028 | 0.0091 | 0.0091 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0934 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0574 | 0.0574 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0271 | 0.2753 | 0.2753 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0333 | 0.3428 | 0.3428 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0031 | 0.012 | 0.012 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0574 | 0.0574 |
Leishmania major | hypothetical protein, conserved | 0.0247 | 0.2482 | 0.2482 |
Plasmodium falciparum | adenosylhomocysteinase | 0.0934 | 1 | 1 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0934 | 1 | 1 |
Echinococcus multilocularis | Aminotransferase class III | 0.0023 | 0.0037 | 0.0037 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0028 | 0.0091 | 0.0091 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0934 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0934 | 1 | 1 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0934 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.016 | 0.1532 | 0.1532 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0578 | 0.6106 | 0.6106 |
Schistosoma mansoni | thyroid hormone receptor | 0.016 | 0.1532 | 0.1532 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.012 | 0.012 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.012 | 0.012 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.012 | 0.012 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0919 | 0.9839 | 0.9839 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.3428 | 0.3428 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0031 | 0.012 | 0.012 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0247 | 0.2482 | 0.2455 |
Loa Loa (eye worm) | glutaminase 2 | 0.0551 | 0.5809 | 0.5809 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0467 | 0.0431 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0707 | 0.7522 | 0.7522 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0066 | 0.0508 | 0.0508 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0039 | 0.0211 | 0.0211 |
Mycobacterium ulcerans | hypothetical protein | 0.0162 | 0.1558 | 0.1527 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0937 | 0.0937 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0063 | 0.047 | 0.047 |
Echinococcus multilocularis | Kelch repeat type 1 | 0.0093 | 0.0799 | 0.0799 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.0228 | 0.2275 | 0.2275 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.007 | 0.0545 | 0.0545 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0051 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0919 | 0.9839 | 0.9839 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0031 | 0.012 | 0.012 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0934 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0934 | 1 | 1 |
Brugia malayi | isocitrate dehydrogenase | 0.0051 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0293 | 0.0293 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0031 | 0.012 | 0.012 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0129 | 0.1196 | 0.1196 |
Mycobacterium leprae | PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA | 0.0162 | 0.1558 | 0.1527 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0105 | 0.0937 | 0.0937 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.012 | 0.012 |
Echinococcus multilocularis | geminin | 0.0174 | 0.1688 | 0.1688 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.0934 | 1 | 1 |
Brugia malayi | Isocitrate dehydrogenase | 0.0051 | 0.0343 | 0.0343 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.012 | 0.012 |
Brugia malayi | MH1 domain containing protein | 0.0063 | 0.047 | 0.047 |
Echinococcus multilocularis | ornithine aminotransferase | 0.0023 | 0.0037 | 0.0037 |
Brugia malayi | glutaminase DH11.1 | 0.0551 | 0.5809 | 0.5809 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0574 | 0.0574 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | smad1 5 8 and | 0.0063 | 0.047 | 0.047 |
Brugia malayi | calpain family protein 1 | 0.0066 | 0.0508 | 0.0508 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0028 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0063 | 0.047 | 0.047 |
Schistosoma mansoni | glutaminase | 0.0551 | 0.5809 | 0.5809 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0051 | 0.0343 | 0.0343 |
Brugia malayi | MH2 domain containing protein | 0.0063 | 0.047 | 0.047 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0072 | 0.0574 | 0.0574 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0247 | 0.2482 | 0.2455 |
Mycobacterium tuberculosis | Probable aminotransferase | 0.0162 | 0.1558 | 0.1527 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0028 | 0.0091 | 0.0091 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0105 | 0.0937 | 0.0937 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0363 | 0.0363 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0051 | 0.0343 | 0.0343 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0051 | 0.0343 | 0.0343 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0934 | 1 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0299 | 0.306 | 0.306 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0072 | 0.0574 | 0.0574 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.1688 | 0.1688 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0053 | 0.0363 | 0.0363 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0021 | 0.0014 | 0.0014 |
Echinococcus granulosus | geminin | 0.0174 | 0.1688 | 0.1688 |
Schistosoma mansoni | hypothetical protein | 0.0105 | 0.0937 | 0.0937 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0031 | 0.012 | 0.012 |
Brugia malayi | Muscleblind-like protein | 0.0299 | 0.306 | 0.306 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0031 | 0.012 | 0.012 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.0934 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0031 | 0.012 | 0.012 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0467 | 0.0467 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0031 | 0.012 | 0.012 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0934 | 1 | 1 |
Mycobacterium tuberculosis | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA | 0.0162 | 0.1558 | 0.1527 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | smad | 0.0063 | 0.047 | 0.047 |
Echinococcus granulosus | Aminotransferase class III | 0.0023 | 0.0037 | 0.0037 |
Echinococcus granulosus | GPCR family 2 | 0.0105 | 0.0937 | 0.0937 |
Schistosoma mansoni | hypothetical protein | 0.0105 | 0.0937 | 0.0937 |
Schistosoma mansoni | ornithine--oxo-acid transaminase | 0.0023 | 0.0037 | 0.0037 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.0111 | 0.0995 | 0.0995 |
Echinococcus granulosus | kelch ECH associated protein 1 like | 0.0092 | 0.0796 | 0.0796 |
Brugia malayi | hypothetical protein | 0.0159 | 0.1526 | 0.1526 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0164 | 0.0164 |
Schistosoma mansoni | Smad4 | 0.0028 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.012 | 0.012 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.0366 | 0.3788 | 0.3788 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0049 | 0.0319 | 0.0319 |
Brugia malayi | MH1 domain containing protein | 0.0063 | 0.047 | 0.047 |
Echinococcus granulosus | calpain A | 0.007 | 0.0545 | 0.0545 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0934 | 1 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0467 | 0.0431 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0271 | 0.2753 | 0.2753 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | smad | 0.0028 | 0.0091 | 0.0091 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0066 | 0.0508 | 0.0508 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0105 | 0.0937 | 0.0937 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.0467 | 0.0467 |
Brugia malayi | calpain family protein 1 | 0.0066 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.012 | 0.012 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.016 | 0.1532 | 0.1532 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0028 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.306 | 0.306 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0031 | 0.012 | 0.012 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0031 | 0.012 | 0.012 |
Brugia malayi | MH2 domain containing protein | 0.0063 | 0.047 | 0.047 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.1688 | 0.1688 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0051 | 0.0343 | 0.0343 |
Brugia malayi | RNA binding protein | 0.0271 | 0.2753 | 0.2753 |
Brugia malayi | MH2 domain containing protein | 0.0919 | 0.9839 | 0.9839 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0247 | 0.2482 | 0.2482 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0051 | 0.0343 | 0.0308 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | smad1 5 8 and | 0.0063 | 0.047 | 0.047 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0053 | 0.0363 | 0.0363 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0578 | 0.6106 | 0.6106 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.007 | 0.0545 | 0.0545 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0063 | 0.047 | 0.047 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0111 | 0.0995 | 0.0995 |
Schistosoma mansoni | Smad4 | 0.0063 | 0.047 | 0.047 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.012 | 0.012 |
Echinococcus granulosus | FTZ F1 alpha | 0.0031 | 0.012 | 0.012 |
Onchocerca volvulus | 0.0031 | 0.012 | 0.1453 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0467 | 0.0467 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0051 | 0.0343 | 0.0308 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0293 | 0.2991 | 0.1698 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.012 | 0.012 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0028 | 0.0091 | 0.0091 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.0366 | 0.3788 | 0.3788 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | tar DNA-binding protein | 0.0271 | 0.2753 | 0.2753 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.012 | 0.012 |
Loa Loa (eye worm) | Smad1 | 0.0063 | 0.047 | 0.047 |
Echinococcus granulosus | tar DNA binding protein | 0.0271 | 0.2753 | 0.2753 |
Brugia malayi | nuclear hormone receptor | 0.0031 | 0.012 | 0.012 |
Echinococcus multilocularis | smad | 0.0063 | 0.047 | 0.047 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0031 | 0.012 | 0.1453 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0085 | 0.0712 | 0.0712 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0574 | 0.0574 |
Brugia malayi | Smad1 | 0.0063 | 0.047 | 0.047 |
Trichomonas vaginalis | glutaminase, putative | 0.0551 | 0.5809 | 0.5036 |
Schistosoma mansoni | tar DNA-binding protein | 0.0271 | 0.2753 | 0.2753 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0837 | 0.8941 | 0.8941 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.012 | 0.012 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0063 | 0.047 | 0.047 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.012 | 0.012 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0063 | 0.047 | 0.047 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0247 | 0.2482 | 0.2482 |
Echinococcus multilocularis | kelch ECH associated protein 1 | 0.0092 | 0.0796 | 0.0796 |
Schistosoma mansoni | coup transcription factor | 0.0031 | 0.012 | 0.012 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0072 | 0.0574 | 0.0574 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0031 | 0.012 | 0.012 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0574 | 0.0574 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0043 | 0.0255 | 0.0255 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0467 | 0.0431 |
Loa Loa (eye worm) | glutamate receptor | 0.0043 | 0.0255 | 0.0255 |
Brugia malayi | steroid hormone receptor | 0.0031 | 0.012 | 0.012 |
Brugia malayi | 4-aminobutyrate aminotransferase, mitochondrial precursor | 0.0023 | 0.0037 | 0.0037 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0036 | 0.0178 | 0.0178 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0051 | 0.0343 | 0.0343 |
Brugia malayi | MH1 domain containing protein | 0.0035 | 0.0164 | 0.0164 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0111 | 0.0995 | 0.0995 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0031 | 0.012 | 0.012 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0574 | 0.0574 |
Schistosoma mansoni | hypothetical protein | 0.0093 | 0.0799 | 0.0799 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0293 | 0.0293 |
Echinococcus granulosus | adenosylhomocysteinase | 0.0934 | 1 | 1 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.0934 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.012 | 0.012 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0063 | 0.047 | 0.047 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0051 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0031 | 0.012 | 0.012 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0247 | 0.2482 | 0.2455 |
Wolbachia endosymbiont of Brugia malayi | acetylornithine transaminase protein | 0.0023 | 0.0037 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.012 | 0.012 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0031 | 0.012 | 0.012 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0031 | 0.012 | 0.012 |
Loa Loa (eye worm) | TAR-binding protein | 0.0271 | 0.2753 | 0.2753 |
Echinococcus multilocularis | tar DNA binding protein | 0.0271 | 0.2753 | 0.2753 |
Schistosoma mansoni | tar DNA-binding protein | 0.0271 | 0.2753 | 0.2753 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0031 | 0.012 | 0.1453 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0707 | 0.7522 | 0.7522 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0105 | 0.0937 | 0.0937 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0046 | 0.0293 | 0.0293 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0051 | 0.0343 | 0.0308 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.0934 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0031 | 0.012 | 0.012 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0028 | 0.0091 | 0.0091 |
Brugia malayi | MH1 domain containing protein | 0.0035 | 0.0164 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0712 | 0.0712 |
Echinococcus multilocularis | calpain A | 0.007 | 0.0545 | 0.0545 |
Schistosoma mansoni | hypothetical protein | 0.0129 | 0.1196 | 0.1196 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0051 | 0.0343 | 0.0343 |
Schistosoma mansoni | tar DNA-binding protein | 0.0271 | 0.2753 | 0.2753 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0467 | 0.0467 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0031 | 0.012 | 0.012 |
Loa Loa (eye worm) | RNA binding protein | 0.0271 | 0.2753 | 0.2753 |
Brugia malayi | ecdysteroid receptor | 0.0031 | 0.012 | 0.012 |
Mycobacterium ulcerans | glutaminase | 0.0551 | 0.5809 | 0.5793 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0063 | 0.047 | 0.047 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.012 | 0.012 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0031 | 0.012 | 0.012 |
Echinococcus multilocularis | Smad4 | 0.0063 | 0.047 | 0.047 |
Chlamydia trachomatis | glutamate-1-semialdehyde-2,1-aminomutase | 0.0023 | 0.0037 | 0.5 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0707 | 0.7522 | 0.7522 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0051 | 0.0343 | 0.0343 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0031 | 0.012 | 0.012 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0036 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0051 | 0.0343 | 0.0343 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0031 | 0.012 | 0.1453 |
Echinococcus multilocularis | GPCR, family 2 | 0.0105 | 0.0937 | 0.0937 |
Schistosoma mansoni | tar DNA-binding protein | 0.0271 | 0.2753 | 0.2753 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0105 | 0.0937 | 0.0937 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0031 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0578 | 0.6106 | 0.6106 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0508 | 0.0508 |
Echinococcus granulosus | ornithine aminotransferase | 0.0023 | 0.0037 | 0.0037 |
Schistosoma mansoni | hypothetical protein | 0.0105 | 0.0937 | 0.0937 |
Echinococcus multilocularis | muscleblind protein | 0.0299 | 0.306 | 0.306 |
Brugia malayi | hypothetical protein | 0.0247 | 0.2482 | 0.2482 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0247 | 0.2482 | 0.2482 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0051 | 0.0343 | 0.0343 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0051 | 0.0343 | 0.0343 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.007 | 0.0545 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.2275 | 0.2275 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.0934 | 1 | 1 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.007 | 0.0545 | 0.0545 |
Brugia malayi | nuclear receptor NHR-88 | 0.0031 | 0.012 | 0.012 |
Echinococcus granulosus | muscleblind protein | 0.0299 | 0.306 | 0.306 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.0366 | 0.3788 | 0.3788 |
Echinococcus granulosus | smad | 0.0063 | 0.047 | 0.047 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0105 | 0.0937 | 0.0937 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0031 | 0.012 | 0.012 |
Echinococcus granulosus | Smad4 | 0.0063 | 0.047 | 0.047 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0051 | 0.0343 | 0.0343 |
Echinococcus multilocularis | kelch ECH associated protein 1 | 0.0092 | 0.0796 | 0.0796 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0031 | 0.012 | 0.012 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0105 | 0.0937 | 0.0937 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | Smad4 | 0.0028 | 0.0091 | 0.0091 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0051 | 0.0343 | 0.0343 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0036 | 0.0178 | 0.0178 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0467 | 0.0431 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0051 | 0.0343 | 0.0308 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.012 | 0.012 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.0467 | 0.0431 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0085 | 0.0712 | 0.0712 |
Loa Loa (eye worm) | glutaminase | 0.0551 | 0.5809 | 0.5809 |
Echinococcus multilocularis | ornithine aminotransferase | 0.0023 | 0.0037 | 0.0037 |
Echinococcus granulosus | kelch ECH associated protein 1 | 0.0092 | 0.0796 | 0.0796 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0129 | 0.1196 | 0.1196 |
Plasmodium vivax | ornithine aminotransferase, putative | 0.0023 | 0.0037 | 0.0037 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0031 | 0.012 | 0.012 |
Onchocerca volvulus | 0.0046 | 0.0293 | 1 | |
Loa Loa (eye worm) | steroid hormone receptor | 0.0031 | 0.012 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.0105 | 0.0937 | 0.0937 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0021 | 0.0014 | 0.0014 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0023 | 0.0033 | 0.0033 |
Brugia malayi | TAR-binding protein | 0.0271 | 0.2753 | 0.2753 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Drug uptake (ADMET) | = 6.39 % ID/g | Drug uptake in ICR mouse bone at 370 kBq/100 ul, iv at 60 mins by gamma-counting analysis | ChEMBL. | 22974116 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.