Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0021 | 0.0861 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.375 | 0.375 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0861 | 0.0861 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.14 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0073 | 0.4963 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0027 | 0.14 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.14 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.14 | 0.14 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.375 | 0.375 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0138 | 1 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0687 | 0.1384 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0027 | 0.14 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.14 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.2332 | 0.4699 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0861 | 0.0861 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0073 | 0.4963 | 0.4963 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.14 | 0.14 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.2332 | 0.2332 |
Onchocerca volvulus | 0.0027 | 0.14 | 0.5 | |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0687 | 0.1384 |
Brugia malayi | TAR-binding protein | 0.0073 | 0.4963 | 0.4963 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0138 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0073 | 0.4963 | 0.4963 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0861 | 0.0861 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.14 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.14 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.4963 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.4963 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0687 | 0.0687 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.14 | 0.14 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.14 | 0.5 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0687 | 0.1384 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.2332 | 0.2332 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.4963 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.14 | 0.14 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0021 | 0.0861 | 0.139 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.14 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0687 | 0.1384 |
Echinococcus granulosus | tar DNA binding protein | 0.0073 | 0.4963 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.14 | 0.14 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0021 | 0.0861 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0687 | 0.1384 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.14 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0861 | 0.0861 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0861 | 0.0861 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.14 | 0.14 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0687 | 0.1384 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0027 | 0.14 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0073 | 0.4963 | 0.4963 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0687 | 0.1384 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.375 | 0.375 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0073 | 0.4963 | 0.4963 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.4963 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.14 | 0.5 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0027 | 0.14 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.14 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.14 | 0.5 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0687 | 0.0687 |
Loa Loa (eye worm) | TAR-binding protein | 0.0073 | 0.4963 | 0.4963 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0027 | 0.14 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0687 | 0.1384 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0687 | 0.0687 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0687 | 0.0687 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0027 | 0.14 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0021 | 0.0861 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.4963 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0027 | 0.14 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.375 | 0.375 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0687 | 0.1384 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0687 | 0.1384 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.