Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.0124 | 0.0981 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0059 | 0.126 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0124 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0629 | 0.0856 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.0124 | 0.5 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0124 | 0.0168 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.6863 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.7349 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0124 | 1 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0059 | 0.126 | 0.1715 |
Echinococcus multilocularis | acetylcholinesterase | 0.0164 | 0.6863 | 0.9339 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0629 | 0.0856 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0059 | 0.126 | 0.1715 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0124 | 0.018 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0059 | 0.126 | 0.1837 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0059 | 0.126 | 0.1715 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0629 | 0.0856 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0124 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0059 | 0.126 | 0.126 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0629 | 0.0916 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0629 | 0.0856 |
Brugia malayi | Carboxylesterase family protein | 0.0164 | 0.6863 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0629 | 0.0856 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0059 | 0.126 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0124 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0124 | 1 |
Echinococcus multilocularis | geminin | 0.0173 | 0.7349 | 1 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0124 | 0.0168 |
Echinococcus granulosus | acetylcholinesterase | 0.0164 | 0.6863 | 0.9339 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0164 | 0.6863 | 0.9339 |
Echinococcus granulosus | carboxylesterase 5A | 0.0164 | 0.6863 | 0.9339 |
Echinococcus granulosus | geminin | 0.0173 | 0.7349 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0124 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0164 | 0.6863 | 0.9339 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0124 | 0.0168 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0059 | 0.126 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0124 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0124 | 0.0981 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.6863 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0164 | 0.6863 | 1 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.0124 | 0.5 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0124 | 0.0168 |
Brugia malayi | Inositol-1 | 0.0037 | 0.0124 | 0.018 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0629 | 0.0856 |
Onchocerca volvulus | 0.0035 | 0 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.0164 | 0.6863 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0629 | 0.0916 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.7349 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0164 | 0.6863 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0164 | 0.6863 | 0.9339 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0055 | 0.1051 | 0.1531 |
Echinococcus multilocularis | acetylcholinesterase | 0.0164 | 0.6863 | 0.9339 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0629 | 0.0856 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.