Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | BTB/POZ domain containing protein | 0.0002 | 0.0003 | 0.0007 |
Onchocerca volvulus | 0.0002 | 0 | 0.5 | |
Echinococcus granulosus | kelch ECH associated protein 1 | 0.0678 | 0.9972 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0002 | 0.0003 | 0.0003 |
Entamoeba histolytica | hypothetical protein | 0.0258 | 0.3781 | 0.5 |
Echinococcus granulosus | kelch protein 12 | 0.0002 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0002 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0002 | 0.0003 | 0.0003 |
Echinococcus granulosus | kelch protein 3 | 0.0002 | 0.0003 | 0.0003 |
Echinococcus multilocularis | ectoderm neural cortex protein 1 | 0.0002 | 0.0003 | 0.0003 |
Onchocerca volvulus | 0.0002 | 0 | 0.5 | |
Loa Loa (eye worm) | ring canal kelch protein | 0.0002 | 0.0003 | 1 |
Echinococcus granulosus | ectoderm neural cortex protein 1 | 0.0002 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.068 | 1 | 1 |
Loa Loa (eye worm) | Klhl5 protein | 0.0002 | 0.0003 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0002 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0258 | 0.3781 | 0.3781 |
Echinococcus multilocularis | kelch ECH associated protein 1 | 0.0678 | 0.9972 | 0.9972 |
Echinococcus multilocularis | kelch protein 18 | 0.0002 | 0.0003 | 0.0003 |
Echinococcus granulosus | kelch protein 18 | 0.0002 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0002 | 0.0003 | 0.0003 |
Brugia malayi | hypothetical protein | 0.0258 | 0.3781 | 1 |
Onchocerca volvulus | 0.0002 | 0 | 0.5 | |
Brugia malayi | Kelch-like protein X | 0.0002 | 0.0003 | 0.0007 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0258 | 0.3781 | 0.3781 |
Echinococcus multilocularis | kelch ECH associated protein 1 | 0.0678 | 0.9972 | 0.9972 |
Entamoeba histolytica | hypothetical protein | 0.0258 | 0.3781 | 0.5 |
Echinococcus granulosus | kelch ECH associated protein 1 like | 0.0678 | 0.9972 | 1 |
Echinococcus granulosus | kelch ECH associated protein 1 like | 0.0678 | 0.9972 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0002 | 0.0003 | 0.0003 |
Onchocerca volvulus | 0.0002 | 0 | 0.5 | |
Echinococcus multilocularis | kelch protein 10 | 0.0002 | 0.0003 | 0.0003 |
Echinococcus multilocularis | kelch protein 3 | 0.0002 | 0.0003 | 0.0003 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0258 | 0.3781 | 0.3792 |
Brugia malayi | Kelch motif family protein | 0.0002 | 0.0003 | 0.0007 |
Echinococcus granulosus | kelch protein 10 | 0.0002 | 0.0003 | 0.0003 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0258 | 0.3781 | 0.3781 |
Echinococcus multilocularis | kelch protein 12 | 0.0002 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | kelch domain-containing protein family protein | 0.0002 | 0.0003 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0002 | 0.0003 | 0.0003 |
Entamoeba histolytica | hypothetical protein | 0.0258 | 0.3781 | 0.5 |
Brugia malayi | Kelch motif family protein | 0.0002 | 0.0003 | 0.0007 |
Entamoeba histolytica | hypothetical protein | 0.0258 | 0.3781 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.